PDBsum entry 7cx7

Isomerase

PDB id: 7cx7

Contents

Protein chains

(+ 0 more) 495 a.a.

Ligands

MPD ×9

GOL

Metals

_MN ×9

Waters ×400

PDB id:

7cx7

Name:

Isomerase

Title:

Crystal structure of arabinose isomerase from hybrid ai8

Structure:

L-arabinose isomerase. Chain: a, b, c, d, e, f. Engineered: yes. Other_details: chimeric protein

Source:

Geobacillus kaustophilus (strain hta426), alicyclobacillus sp. Tp-7, alicyclobacillus acidocaldarius. Organism_taxid: 235909, 1237889, 1388. Gene: araa, gk1904, araa. Expressed in: escherichia coli bl21. Expression_system_taxid: 511693

Resolution:

2.49Å R-factor: 0.196 R-free: 0.268

Authors:

N.K.Q.Hoang,I.Dhanasingh,T.P.Cao,J.Y.Sung,S.M.Shin,D.W.Lee,S.H.Lee

Key ref:

N.K.Q.Hoang et al. Crystal structure of arabinose isomerase from hyper thermophilic bacterium thermotoga maritima (tmai) wt. To be published, .

Date:

01-Sep-20 Release date: 01-Sep-21

Protein chains

K0IGW6  (K0IGW6_9BACL) -  L-arabinose isomerase from Alicyclobacillus sp. TP7

Seq: 494 a.a.

Struc: 495 a.a.*

Protein chains

Q5KYP7  (ARAA_GEOKA) -  L-arabinose isomerase from Geobacillus kaustophilus (strain HTA426)

Seq: 496 a.a.

Struc: 495 a.a.*

* PDB and UniProt seqs differ at 158 residue positions (black crosses)

Enzyme reactions

• Enzyme class: E.C.5.3.1.4 - L-arabinose isomerase.
• Reaction: beta-L-arabinopyranose = L-ribulose

beta-L-arabinopyranose = L-ribulose (Bound ligand (Het Group name = MPD) matches with 63.64% similarity)

• Cofactor: Divalent cation

Molecule diagrams generated from .mol files obtained from the KEGG ftp site