PDBsum entry 7c5c

Ligase

PDB id: 7c5c

Contents

Protein chain

312 a.a.

Ligands

EDO ×2

Waters ×203

PDB id:

7c5c

Name:

Ligase

Title:

Crystal structure of sefrs

Structure:

Tyrosine--tRNA ligase. Chain: a. Synonym: aminoacyl-tRNA synthetase,tyrosyl-tRNA synthetase,tyrrs. Engineered: yes

Source:

Methanocaldococcus jannaschii dsm 2661. Organism_taxid: 243232. Gene: tyrs, mj0389. Expressed in: escherichia coli. Expression_system_taxid: 562

Resolution:

1.72Å R-factor: 0.190 R-free: 0.222

Authors:

J.P.Sun,J.Y.Wang,Z.L.Zhu,Q.T.He

Key ref:

J.P.Sun et al. Crystal structure of sefrs. To be published, .

Date:

19-May-20 Release date: 26-May-21

Protein chain

Q57834  (SYY_METJA) -  Tyrosine--tRNA ligase from Methanocaldococcus jannaschii (strain ATCC 43067 / DSM 2661 / JAL-1 / JCM 10045 / NBRC 100440)

Seq: 306 a.a.

Struc: 312 a.a.*

* PDB and UniProt seqs differ at 8 residue positions (black crosses)

Enzyme reactions

• Enzyme class: E.C.6.1.1.1 - tyrosine--tRNA ligase.
• Reaction: tRNA(Tyr) + L-tyrosine + ATP = L-tyrosyl-tRNA(Tyr) + AMP + diphosphate + H⁺

Molecule diagrams generated from .mol files obtained from the KEGG ftp site