PDBsum entry 7a3c

Protein binding

PDB id: 7a3c

Contents

Protein chains

61 a.a.

Ligands

GOL ×4

SO4 ×2

Waters ×125

PDB id:

7a3c

Name:

Protein binding

Title:

Crystal structure of thE C-src sh3 domain mutant l100i at ph 3.0

Structure:

Proto-oncogene tyrosine-protein kinase src. Chain: a, b, c, d. Synonym: proto-oncogenE C-src,pp60c-src,p60-src. Engineered: yes. Mutation: yes

Source:

Gallus gallus. Chicken. Organism_taxid: 9031. Gene: src. Expressed in: escherichia coli bl21(de3). Expression_system_taxid: 469008.

Resolution:

1.80Å R-factor: 0.192 R-free: 0.228

Authors:

A.Camara-Artigas,M.Plaza-Garrido,M.C.Salinas-Garcia

Key ref:

A.Camara-Artigas et al. Crystal structure of the c-Src sh3 domain mutant l100 3.0. To be published, .

Date:

18-Aug-20 Release date: 25-Aug-21

Protein chains

P00523  (SRC_CHICK) -  Proto-oncogene tyrosine-protein kinase Src from Gallus gallus

Seq: 533 a.a.

Struc: 61 a.a.*

* PDB and UniProt seqs differ at 1 residue position (black cross)

Enzyme reactions

• Enzyme class: E.C.2.7.10.2 - non-specific protein-tyrosine kinase.
• Reaction: L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H⁺

Molecule diagrams generated from .mol files obtained from the KEGG ftp site