PDBsum entry 6u13

Hydrolase

PDB id: 6u13

Contents

Protein chain

266 a.a.

Ligands

MX1

EDO ×3

Metals

_ZN ×2

Waters ×291

PDB id:

6u13

Name:

Hydrolase

Title:

Crystal structure of the metallo-beta-lactamase l1 from stenotrophomonas maltophilia in the complex with the hydrolyzed antibiotic moxalactam

Structure:

Putative metallo-beta-lactamase l1 (beta-lactamase type ii) (ec 3.5.2.6) (penicillinase). Chain: a. Engineered: yes

Source:

Stenotrophomonas maltophilia (strain k279a). Organism_taxid: 522373. Strain: k279a. Gene: smlt2667. Expressed in: escherichia coli bl21(de3). Expression_system_taxid: 469008. Expression_system_variant: gold.

Resolution:

1.52Å R-factor: 0.129 R-free: 0.160

Authors:

Y.Kim,N.Maltseva,M.Endres,A.Joachimiak,Center For Structural Genomics Of Infectious Diseases (Csgid)

Key ref:

Y.Kim et al. Crystal structure of the metallo-Beta-Lactamase l1 fr stenotrophomonas maltophilia in the complex with the hydrolyzed antibiotic moxalactam.. To be published, .

Date:

15-Aug-19 Release date: 11-Sep-19

Protein chain

B2FTM1  (B2FTM1_STRMK) -  Metallo-beta-lactamase l1 (Beta-lactamase type ii) (Ec 3.5.2.6) (Penicillinase) from Stenotrophomonas maltophilia (strain K279a)

Seq: 290 a.a.

Struc: 266 a.a.

Enzyme reactions

• Enzyme class: E.C.3.5.2.6 - beta-lactamase.
• Pathway: Penicillin Biosynthesis and Metabolism
• Reaction: a beta-lactam + H2O = a substituted beta-amino acid
• Cofactor: Zn(2+)