PDBsum entry 6kpy

Membrane protein

PDB id: 6kpy

Contents

Protein chains

996 a.a.

289 a.a.

32 a.a.

Ligands

NAG-NAG ×4

1AT ×2

F9U ×2

NAG ×2

CLR ×2

Metals

_MG ×4

_NA ×2

Waters ×10

PDB id:

6kpy

Name:

Membrane protein

Title:

Crystal structures of na+,k+-atpase in complex with istaroxime

Structure:

Sodium/potassium-transporting atpase subunit alpha. Chain: a, c. Sodium/potassium-transporting atpase subunit beta-1. Chain: b, d. Synonym: sodium/potassium-dependent atpase subunit beta-1. Fxyd domain-containing ion transport regulator. Chain: g, e. Synonym: na+/k+ atpase gamma subunit transcript variant a

Source:

Sus scrofa. Pig. Organism_taxid: 9823. Organism_taxid: 9823

Resolution:

3.71Å R-factor: 0.182 R-free: 0.229

Authors:

H.Ogawa,K.Motoyama,F.Cornelius,B.Vilsen,C.Toyoshima

Key ref:

H.Ogawa et al. X-Ray crystal structures of na+,K+-Atpase in complex cardiotonic steroids. To be published, .

Date:

16-Aug-19 Release date: 02-Sep-20

Protein chains

A0A5G2QZU7  () -  Sodium/potassium-transporting ATPase subunit alpha from Sus scrofa

Seq: 1021 a.a.

Struc: 996 a.a.*

Protein chains

P05027  (AT1B1_PIG) -  Sodium/potassium-transporting ATPase subunit beta-1 from Sus scrofa

Seq: 303 a.a.

Struc: 289 a.a.

Protein chains

Q58K79  (Q58K79_PIG) -  FXYD domain-containing ion transport regulator from Sus scrofa

Seq: 65 a.a.

Struc: 32 a.a.

* PDB and UniProt seqs differ at 1 residue position (black cross)