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PDBsum entry 4zqb
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Oxidoreductase
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PDB id
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4zqb
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PDB id:
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| Name: |
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Oxidoreductase
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Title:
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Crystal structure of NADP-dependent dehydrogenase from rhodobactersphaeroides in complex with NADP and sulfate
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Structure:
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NADP-dependent dehydrogenase. Chain: a, b. Engineered: yes
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Source:
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Rhodobacter sphaeroides (strain atcc 17023 / 2.4.1 / ncib 8253 / dsm 158). Organism_taxid: 272943. Strain: atcc 17023 / 2.4.1 / ncib 8253 / dsm 158. Gene: rsp_3442. Expressed in: escherichia coli. Expression_system_taxid: 469008.
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Resolution:
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1.85Å
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R-factor:
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0.167
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R-free:
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0.200
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Authors:
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M.Kowiel,O.A.Gasiorowska,I.G.Shabalin,K.B.Handing,P.J.Porebski, J.Bonanno,S.C.Almo,W.Minor,New York Structural Genomics Research Consortium (Nysgrc)
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Key ref:
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M.Kowiel
et al.
Crystal structure of NADP-Dependent dehydrogenase fro rhodobactersphaeroides in complex with NADP and sulfa.
To be published,
.
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Date:
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08-May-15
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Release date:
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20-May-15
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PROCHECK
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Headers
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References
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Q3IWN8
(Q3IWN8_RHOS4) -
2-hydroxyacid dehydrogenase from Cereibacter sphaeroides (strain ATCC 17023 / DSM 158 / JCM 6121 / CCUG 31486 / LMG 2827 / NBRC 12203 / NCIMB 8253 / ATH 2.4.1.)
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Seq:
Struc:
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313 a.a.
313 a.a.
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Key: |
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Secondary structure |
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CATH domain |
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Enzyme class 1:
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E.C.1.1.1.79
- glyoxylate reductase (NADP(+)).
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Reaction:
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glycolate + NADP+ = glyoxylate + NADPH + H+
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glycolate
Bound ligand (Het Group name = )
matches with 57.14% similarity
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+
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NADP(+)
Bound ligand (Het Group name = )
corresponds exactly
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=
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glyoxylate
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NADPH
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+
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H(+)
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Enzyme class 2:
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E.C.1.1.1.81
- hydroxypyruvate reductase.
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Reaction:
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1.
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(R)-glycerate + NAD+ = 3-hydroxypyruvate + NADH + H+
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2.
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(R)-glycerate + NADP+ = 3-hydroxypyruvate + NADPH + H+
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(R)-glycerate
Bound ligand (Het Group name = )
matches with 85.71% similarity
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+
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NAD(+)
Bound ligand (Het Group name = )
matches with 91.67% similarity
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=
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3-hydroxypyruvate
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+
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NADH
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+
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H(+)
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(R)-glycerate
Bound ligand (Het Group name = )
matches with 85.71% similarity
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+
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NADP(+)
Bound ligand (Het Group name = )
corresponds exactly
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=
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3-hydroxypyruvate
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+
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NADPH
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+
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H(+)
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Note, where more than one E.C. class is given (as above), each may
correspond to a different protein domain or, in the case of polyprotein
precursors, to a different mature protein.
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Molecule diagrams generated from .mol files obtained from the
KEGG ftp site
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Links
