PDBsum entry 3oqh

Ligase

PDB id

3oqh

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Contents

			Protein chains

					215 a.a. *

			Ligands

					GOL

			Waters ×475

* Residue conservation analysis

PDB id:

3oqh

Links

Name:

Ligase

Title:

Crystal structure of b. Licheniformis cdps yvmc-blic

Structure:

Putative uncharacterized protein yvmc. Chain: a, b. Synonym: yvmc. Engineered: yes

Source:

Bacillus licheniformis. Organism_taxid: 279010. Strain: atcc 14580. Gene: bl00817, bli03566, yvmc. Expressed in: escherichia coli. Expression_system_taxid: 562.

Resolution:

1.90Å

R-factor:

0.181

R-free:

0.205

Authors:

L.Bonnefond,T.Arai,T.Suzuki,R.Ishitani,O.Nureki

Key ref:

L.Bonnefond et al. (2011). Structural basis for nonribosomal peptide synthesis by an aminoacyl-tRNA synthetase paralog. Proc Natl Acad Sci U S A, 108, 3912-3917. PubMed id: 21325056

Date:

03-Sep-10

Release date:

23-Feb-11

PROCHECK

	Headers

	References

Protein chains

Q65EX3 (CDLS_BACLD) - Cyclo(L-leucyl-L-leucyl) synthase from Bacillus licheniformis (strain ATCC 14580 / DSM 13 / JCM 2505 / CCUG 7422 / NBRC 12200 / NCIMB 9375 / NCTC 10341 / NRRL NRS-1264 / Gibson 46)

Seq: Struc:					249 a.a. 215 a.a.

Key:

PfamA domain

Secondary structure

CATH domain



		Enzyme reactions

Enzyme class:

E.C.2.3.2.22 - cyclo(L-leucyl-L-leucyl) synthase.

[IntEnz] [ExPASy] [KEGG] [BRENDA]

Reaction:

2 L-leucyl-tRNA(Leu) = cyclo(L-leucyl-L-leucyl) + 2 tRNA(Leu) + 2 H(+)

2 × L-leucyl-tRNA(Leu)	=	cyclo(L-leucyl-L-leucyl)	+	2 × tRNA(Leu)	+	2 × H(+)

Molecule diagrams generated from .mol files obtained from the KEGG ftp site

Added reference

	Proc Natl Acad Sci U S A 108:3912-3917 (2011)
PubMed id: 21325056

Structural basis for nonribosomal peptide synthesis by an aminoacyl-tRNA synthetase paralog.
L.Bonnefond, T.Arai, Y.Sakaguchi, T.Suzuki, R.Ishitani, O.Nureki.

ABSTRACT

No abstract given.