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PDBsum entry 3rj4
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protein ligands metals Protein-protein interface(s) links
Oxidoreductase PDB id
3rj4

 

 

 

 

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Contents
Protein chains
259 a.a.
Ligands
GOL
SO4
Metals
_CL ×2
Waters ×447
PDB id:
3rj4
Name: Oxidoreductase
Title: Crystal structure of 7-cyano-7-deazaguanine reductase, quef from vibrio cholerae
Structure: 7-cyano-7-deazaguanine reductase quef. Chain: a, b. Engineered: yes. Mutation: yes
Source: Vibrio cholerae o1 biovar el tor. Organism_taxid: 243277. Strain: n16961. Gene: quef. Expressed in: escherichia coli. Expression_system_taxid: 511693.
Resolution:
1.75Å     R-factor:   0.163     R-free:   0.191
Authors: Y.Kim,M.Zhou,M.Gu,W.F.Anderson,A.Joachimiak,Center For Structural Genomics Of Infectious Diseases (Csgid)
Key ref: Y.Kim et al. Crystal structure of 7-Cyano-7-Deazaguanine reductase from vibrio cholerae. To be published, .
Date:
15-Apr-11     Release date:   10-Aug-11    
PROCHECK
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 Headers
 References

Protein chains
Q9KTK0  (QUEF_VIBCH) -  NADPH-dependent 7-cyano-7-deazaguanine reductase from Vibrio cholerae serotype O1 (strain ATCC 39315 / El Tor Inaba N16961)
Seq:
Struc: 		281 a.a.
259 a.a.*
Key:    Secondary structure  CATH domain
* PDB and UniProt seqs differ at 1 residue position (black cross)

 Enzyme reactions 
   Enzyme class: E.C.1.7.1.13  - preQ1 synthase.
[IntEnz]   [ExPASy]   [KEGG]   [BRENDA]
      Reaction: 7-aminomethyl-7-carbaguanine + 2 NADP+ = 7-cyano-7-deazaguanine + 2 NADPH + 3 H+
7-aminomethyl-7-carbaguanine
 + 2 × NADP(+)
 = 7-cyano-7-deazaguanine
 + 2 × NADPH
 + 3 × H(+)
Molecule diagrams generated from .mol files obtained from the KEGG ftp site

 

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