PDBsum entry 2fu6

Hydrolase

PDB id: 2fu6

Contents

Protein chains

266 a.a. *

Ligands

SO4 ×8

GOL ×3

Waters ×527

* Residue conservation analysis

PDB id:

2fu6

Name:

Hydrolase

Title:

Zinc-beta-lactamase l1 from stenotrophomonas maltophilia (apo form)

Structure:

Metallo-beta-lactamase l1. Chain: a, b. Synonym: beta-lactamase type ii, penicillinase. Engineered: yes

Source:

Stenotrophomonas maltophilia. Organism_taxid: 40324. Strain: iid 1275. Cellular_location: periplasm. Gene: l1. Expressed in: escherichia coli. Expression_system_taxid: 562.

Resolution:

2.05Å R-factor: 0.163 R-free: 0.209

Authors:

L.Nauton,G.Garau,R.Kahn,O.Dideberg

Key ref:

L.Nauton et al. Crystal structure of the zinc-Beta-Lactamase l1 from stenotrophomonas maltophilia (apo form). To be published, .

Date:

26-Jan-06 Release date: 30-Jan-07

Protein chains

P52700  (BLA1_STEMA) -  Metallo-beta-lactamase L1 type 3 from Stenotrophomonas maltophilia

Seq: 290 a.a.

Struc: 266 a.a.

Enzyme reactions

• Enzyme class: E.C.3.5.2.6 - beta-lactamase.
• Pathway: Penicillin Biosynthesis and Metabolism
• Reaction: a beta-lactam + H2O = a substituted beta-amino acid
• Cofactor: Zn(2+)