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PDBsum entry 2qkq

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protein metals Protein-protein interface(s) links
Transferase PDB id
2qkq

 

 

 

 

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JSmol PyMol  
Contents
Protein chain
61 a.a. *
Metals
_CL ×2
Waters ×33
* Residue conservation analysis
PDB id:
2qkq
Name: Transferase
Title: Structure of the sam domain of human ephrin type-b receptor 4
Structure: Ephrin type-b receptor 4. Chain: a, b. Fragment: sam (sterile alpha motif) domain. Synonym: tyrosine-protein kinase receptor htk, tyrosine-protein kinase tyro11. Engineered: yes
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: ephb4, htk, tyro11. Expressed in: escherichia coli bl21(de3). Expression_system_taxid: 469008.
Resolution:
2.10Å     R-factor:   0.221     R-free:   0.244
Authors: J.R.Walker,D.Cuerrier,C.Butler-Cole,J.Weigelt,C.H.Arrowsmith, A.M.Edwards,A.Bochkarev,S.Dhe-Paganon,Structural Genomics Consortium (Sgc)
Key ref: J.R.Walker et al. Sam domain of human ephrin type-B receptor 4 (ephb4). To be published, .
Date:
11-Jul-07     Release date:   24-Jul-07    
PROCHECK
Go to PROCHECK summary
 Headers
 References

Protein chains
Pfam   ArchSchema ?
P54760  (EPHB4_HUMAN) -  Ephrin type-B receptor 4 from Homo sapiens
Seq:
Struc:
 
Seq:
Struc:
987 a.a.
61 a.a.
Key:    PfamA domain  Secondary structure  CATH domain

 Enzyme reactions 
   Enzyme class: E.C.2.7.10.1  - receptor protein-tyrosine kinase.
[IntEnz]   [ExPASy]   [KEGG]   [BRENDA]
      Reaction: L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H+
L-tyrosyl-[protein]
+ ATP
= O-phospho-L-tyrosyl-[protein]
+ ADP
+ H(+)
Molecule diagrams generated from .mol files obtained from the KEGG ftp site

 

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