PDBsum entry 1vko

Isomerase

PDB id: 1vko

Contents

Protein chain

511 a.a. *

Ligands

NAD

POP

Metals

__K

_CL ×2

IOD ×2

Waters ×149

* Residue conservation analysis

PDB id:

1vko

Name:

Isomerase

Title:

Crystal structure of inositol-3-phosphate synthase (ce21227) from caenorhabditis elegans at 2.30 a resolution

Structure:

Inositol-3-phosphate synthase. Chain: a. Engineered: yes

Source:

Caenorhabditis elegans. Organism_taxid: 6239. Gene: ce21227. Expressed in: escherichia coli. Expression_system_taxid: 562.

Biol. unit:

Tetramer (from PDB file)

Resolution:

2.30Å R-factor: 0.204 R-free: 0.265

Authors:

Joint Center For Structural Genomics (Jcsg)

Key ref:

Joint center for structural genomics (jcsg) Crystal structure of inositol-3-Phosphate synthase (ce21227) from caenorhabditis elegans at 2.30 a resolution. To be published, .

Date:

11-Jun-04 Release date: 17-Aug-04

Protein chain

Q18664  (Q18664_CAEEL) -

Enzyme reactions

• Enzyme class: E.C.5.5.1.4 - inositol-3-phosphate synthase.
• Pathway: myo-Inositol Biosynthesis
• Reaction: D-glucose 6-phosphate = 1D-myo-inositol 3-phosphate
• Cofactor: NAD(+)

NAD(+) (Bound ligand (Het Group name = NAD) corresponds exactly)

Molecule diagrams generated from .mol files obtained from the KEGG ftp site