PDBsum entry 1vjv

Hydrolase

PDB id: 1vjv

Contents

Protein chain

367 a.a. *

Waters ×241

* Residue conservation analysis

PDB id:

1vjv

Name:

Hydrolase

Title:

Crystal structure of ubiquitin carboxyl-terminal hydrolase 6 (yfr010w) from saccharomyces cerevisiae at 1.74 a resolution

Structure:

Ubiquitin carboxyl-terminal hydrolase 6. Chain: a. Fragment: residues 97-499. Synonym: ubiquitin thiolesterase 6, ubiquitin-specific processing protease 6, deubiquitinating enzyme 6. Engineered: yes

Source:

Saccharomyces cerevisiae. Baker's yeast. Organism_taxid: 4932. Gene: ubp6, yfr010w. Expressed in: escherichia coli. Expression_system_taxid: 562.

Resolution:

1.74Å R-factor: 0.181 R-free: 0.209

Authors:

Joint Center For Structural Genomics (Jcsg)

Key ref:

Joint center for structural genomics (jcsg) Crystal structure of ubiquitin carboxyl-Terminal hydrolase 6 (yfr010w) from saccharomyces cerevisiae at 1.74 a resolution. To be published, .

Date:

29-Mar-04 Release date: 21-Sep-04

Protein chain

P43593  (UBP6_YEAST) -  Ubiquitin carboxyl-terminal hydrolase 6 from Saccharomyces cerevisiae (strain ATCC 204508 / S288c)

Seq: 499 a.a.

Struc: 367 a.a.*

* PDB and UniProt seqs differ at 1 residue position (black cross)

Enzyme reactions

• Enzyme class: E.C.3.4.19.12 - ubiquitinyl hydrolase 1.
• Reaction: Thiol-dependent hydrolysis of ester, thiolester, amide, peptide and isopeptide bonds formed by the C-terminal Gly of ubiquitin (a 76-residue protein attached to proteins as an intracellular targeting signal).