 |
|
PDB code
|
|
Protein
|
|
|
|
|
|
Structural basis for the specificity of ubiquitin c-terminal hydrolases
|
|
|
Source: Synthetic: yes. Other_details: the protein was chemically synthesized. The sequence of this protein is naturally found in the cytoplasm of plasmid p- 1a2/trpyuh1-1 of saccharomyces cerevisiae (baker's yeast). The expression system was escherichia coli, strain mm294, plasmid p- 1a2/trpyuh1-1.. 1a2/trpyuh1-1.
|
|
|
Chains:
A, C
(214 residues)
CATH domain:
|
|
|
|
|
|
Solution structure of the cap-gly domain from human cylindromatosis tomour-suppressor cyld
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: fh04363. Other_details: cell-free protein synthesis
|
|
|
Chain:
A
(104 residues)
CATH domain:
|
|
|
|
|
|
Structure of coronavirus main proteinase reveals combination of a chymotrypsin fold with an extra alpha-helical domain
|
|
|
Source: Transmissible gastroenteritis virus. Organism_taxid: 11149. Gene: orf1a. Expressed in: escherichia coli. Expression_system_taxid: 562.
|
|
|
Chains:
A, B, C, D, E, F
(299 residues)
CATH domains:
|
|
|
|
|
|
Nsp4 proteinase from equine arteritis virus
|
|
|
Source: Equine arteritis virus. Organism_taxid: 11047. Gene: nsp4. Expressed in: escherichia coli. Expression_system_taxid: 562.
|
|
|
Chains:
A, B, C, D
(198 residues)
CATH domains:
|
|
|
|
|
|
Structure of the catalytic domain of usp7 (hausp)
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: usp7. Expressed in: escherichia coli. Expression_system_taxid: 562.
|
|
|
Chains:
A, B
(332 residues)
CATH domains:
Unassigned
|
|
|
|
|
|
Crystal structure of a ubp-family deubiquitinating enzyme in isolation and in complex with ubiquitin aldehyde
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: usp7. Expressed in: escherichia coli. Expression_system_taxid: 562. Gene: uba52. Expression_system_taxid: 562
|
|
|
Chains:
A, B, E
(347 residues)
CATH domains:
Unassigned
|
|
|
|
|
|
Coronavirus main proteinase (3clpro) structure: basis for design of anti-sars drugs
|
|
|
Source: Human coronavirus. Organism_taxid: 11137. Strain: 229e. Gene: orf1a. Expressed in: escherichia coli. Expression_system_taxid: 562.
|
|
|
Chains:
A, B
(300 residues)
CATH domains:
|
|
|
|
|
|
Coronavirus main proteinase (3clpro) structure: basis for design of anti-sars drugs
|
|
|
Source: Transmissible gastroenteritis virus. Organism_taxid: 11149. Gene: orf1a. Expressed in: escherichia coli. Expression_system_taxid: 562. Synthetic: yes. Other_details: substrate-analog
|
|
|
Chains:
A, B, C, D, E, F
(299 residues)
CATH domains:
|
|
|
|
|
|
X-ray crystal structure of the sars coronavirus main protease
|
|
|
Source: Severe acute respiratory syndrome-related coronavirus. Sars-cov. Organism_taxid: 694009. Gene: 1a. Expressed in: escherichia coli. Expression_system_taxid: 562.
|
|
|
Chains:
A, B
(295 residues)
CATH domains:
|
|
|
|
|
|
Crystal structure of sars coronavirus nsp9
|
|
|
Source: Sars coronavirus. Organism_taxid: 227859. Strain: frankfurt 1. Gene: nsp9. Expressed in: escherichia coli. Expression_system_taxid: 562.
|
|
|
Chains:
A, B
(111 residues)
CATH domain:
|
|
|
|
|
|
Structure of otubain-2
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: otub2, otb2, otu2, c14orf137. Expressed in: escherichia coli bl21(de3). Expression_system_taxid: 469008.
|
|
|
Chain:
A
(221 residues)
CATH domains:
|
|
|
|
|
|
Deubiquitinating enzyme uch-l3 (human) at 1.8 angstrom resolution
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Cell_line: b834 (de3). Tissue: hematopoetic. Cellular_location: cytoplasm. Expressed in: escherichia coli. Expression_system_taxid: 562. Expression_system_variant: gal-met- auxotroph.
|
|
|
Chain:
A
(206 residues)
CATH domain:
|
|
|
|
|
|
Crystal structure of sars coronavirus main proteinase (3clpro)
|
|
|
Source: Sars coronavirus. Organism_taxid: 227859. Strain: sars. Expressed in: escherichia coli bl21(de3). Expression_system_taxid: 469008.
|
|
|
Chains:
A, B
(301 residues)
CATH domains:
|
|
|
|
|
|
Crystal structure of sars coronavirus main proteinase (3clpro) at ph8.0
|
|
|
Source: Sars coronavirus. Organism_taxid: 227859. Strain: sars. Expressed in: escherichia coli bl21(de3). Expression_system_taxid: 469008.
|
|
|
Chains:
A, B
(302 residues)
CATH domains:
|
|
|
|
|
|
Crystal structure of sars coronavirus main proteinase (3clpro) at ph7.6
|
|
|
Source: Sars coronavirus. Organism_taxid: 227859. Strain: sars. Expressed in: escherichia coli bl21(de3). Expression_system_taxid: 469008.
|
|
|
Chains:
A, B
(301 residues)
CATH domains:
|
|
|
|
|
|
Crystal structure of sars coronavirus main proteinase (3clpro) complexed with an inhibitor
|
|
|
Source: Sars coronavirus. Organism_taxid: 227859. Strain: sars. Gene: rep. Expressed in: escherichia coli bl21(de3). Expression_system_taxid: 469008. Synthetic: yes. Synthetic construct. Organism_taxid: 32630.
|
|
|
Chains:
A, B
(301 residues)
CATH domains:
|
|
|
|
|
|
Nsp9 protein from sars-coronavirus.
|
|
|
Source: Sars coronavirus hku-39849. Organism_taxid: 228404. Cell_line: vero e6. Expressed in: escherichia coli. Expression_system_taxid: 562.
|
|
|
Chain:
A
(122 residues)
CATH domain:
|
|
|
|
|
|
Solution structure of rsgi ruh-013, a uba domain in mouse cdna
|
|
|
Source: Mus musculus. House mouse. Organism_taxid: 10090. Gene: riken cdna 2610101o11. Other_details: cell-free protein synthesis (e.Coli)
|
|
|
Chain:
A
(80 residues)
CATH domain:
|
|
|
|
|
|
Solution structure of rsgi ruh-011, a uba domain from arabidopsis cdna
|
|
|
Source: Arabidopsis thaliana. Thale cress. Organism_taxid: 3702. Gene: arabidopsis thaliana genomic DNA, chromosome 3, tac clone: k10d20. Other_details: cell-free protein synthesis system
|
|
|
Chain:
A
(84 residues)
CATH domain:
|
|
|
|
|
|
Crystal structure of ubiquitin carboxyl-terminal hydrolase 6 (yfr010w) from saccharomyces cerevisiae at 1.74 a resolution
|
|
|
Source: Saccharomyces cerevisiae. Baker's yeast. Organism_taxid: 4932. Gene: ubp6, yfr010w. Expressed in: escherichia coli. Expression_system_taxid: 562.
|
|
|
Chain:
A
(367 residues)
CATH domains:
|
|
|
|
|
|
Solution structure of the dusp domain of husp15
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Expressed in: escherichia coli. Expression_system_taxid: 469008. Other_details: self made cdna library of multiple human carcinoma cell lines
|
|
|
Chain:
A
(120 residues)
CATH domain:
|
|
|
|
|
|
Solution structure of the n-terminal ubiquitin-like domain of mouse ubiquitin specific protease 14 (usp14)
|
|
|
Source: Mus musculus. House mouse. Organism_taxid: 10090. Gene: rekin cdna 2610005k12. Other_details: cell-free protein synthesis
|
|
|
Chain:
A
(96 residues)
CATH domain:
|
|
|
|
|
|
Solution structure of the cs domain of human usp19
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: kazusa cdna hk08201. Other_details: cell-free protein synthesis
|
|
|
Chain:
A
(134 residues)
CATH domain:
|
|
|
|
|
|
Solution structure of the rhodanese-like domain in human ubiquitin specific protease 8 (ubp8)
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: kazusa cdna ha01049. Other_details: cell-free protein synthesis
|
|
|
Chain:
A
(157 residues)
CATH domain:
|
|
|
|
|
|
Solution structure of the 1st cap-gly domain in human cylindromatosis tumor suppressor cyld
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: kazusa cdna fh04363. Other_details: cell-free protein synthesis
|
|
|
Chain:
A
(95 residues)
CATH domain:
|
|
|
|
|
|
Solution structure of the 2nd cap-gly domain in human cylindromatosis tumor suppressor cyld
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: kazusa cdna fh04363. Other_details: cell-free protein synthesis
|
|
|
Chain:
A
(92 residues)
CATH domain:
|
|
|
|
|
|
Solution structure of rsgi ruh-023, a uba domain from arabidopsis cdna
|
|
|
Source: Arabidopsis thaliana. Thale cress. Organism_taxid: 3702. Gene: k10d20. Other_details: cell-free protein synthesis system
|
|
|
Chain:
A
(73 residues)
CATH domain:
|
|
|
|
|
|
Crystal structure of sars-cov mpro in complex with an inhibitor n1
|
|
|
Source: Sars coronavirus. Organism_taxid: 227859. Strain: bj01. Expressed in: escherichia coli bl21(de3). Expression_system_taxid: 469008.
|
|
|
Chains:
A, B
(309 residues)
CATH domains:
|
|
|
|
|
|
Crystal structure of uchl3-ubvme complex
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Expressed in: escherichia coli bl21(de3). Expression_system_taxid: 469008.
|
|
|
Chains:
A, C
(229 residues)
CATH domain:
|
|
|
|
|
|
Nmr structure of the nonstructural protein 7 (nsp7) from the sars coronavirus
|
|
|
Source: Sars coronavirus. Organism_taxid: 227859. Expressed in: escherichia coli. Expression_system_taxid: 562.
|
|
|
Chain:
A
(85 residues)
CATH domain:
|
|
|
|
|
|
The crystal structure of the n-terminal domain of hausp/usp7 complexed with an ebna1 peptide
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: usp7, hausp. Expressed in: escherichia coli bl21. Expression_system_taxid: 511693. Synthetic: yes. Other_details: the sequence of the peptide can be found naturally in epstein-barr virus
|
|
|
Chain:
A
(137 residues)
CATH domain:
|
|
|
|
|
|
Solution structure of the josephin domain of ataxin-3
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Expressed in: escherichia coli bl21(de3). Expression_system_taxid: 469008.
|
|
|
Chain:
A
(182 residues)
CATH domains:
|
|
|
|
|
|
Crystal structure of the n-terminal domain of usp7/hausp.
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: usp7, hausp. Expressed in: escherichia coli bl21(de3). Expression_system_taxid: 469008.
|
|
|
Chains:
A, B, C
(101 residues)
CATH domain:
|
|
|
|
|
|
Crystal structure of native sars clpro
|
|
|
Source: Sars coronavirus. Organism_taxid: 227859
|
|
|
Chain:
A
(301 residues)
CATH domains:
|
|
|
|
|
|
Crystal structure of sars 3clpro c145a mutant
|
|
|
Source: Sars coronavirus. Organism_taxid: 227859
|
|
|
Chains:
A, B
(306 residues)
CATH domains:
|
|
|
|
|
|
Crystal structure of unbound sars coronavirus main peptidase in the space group c2
|
|
|
Source: Sars coronavirus. Organism_taxid: 227859. Strain: sars. Expressed in: escherichia coli. Expression_system_taxid: 562.
|
|
|
Chain:
A
(306 residues)
CATH domains:
|
|
|
|
|
|
Crystal structures of sars coronavirus main peptidase inhibited by an aza-peptide epoxide in the space group c2
|
|
|
Source: Sars coronavirus. Organism_taxid: 227859. Strain: sars. Expressed in: escherichia coli. Expression_system_taxid: 562.
|
|
|
Chain:
A
(306 residues)
CATH domains:
|
|
|
|
|
|
Crystal structures of sars coronavirus main peptidase inhibited by an aza-peptide epoxide in space group p212121
|
|
|
Source: Sars coronavirus. Organism_taxid: 227859. Strain: sars. Expressed in: escherichia coli. Expression_system_taxid: 562.
|
|
|
Chains:
A, B
(304 residues)
CATH domains:
|
|
|
|
|
|
Structure of the n-terminal domain of human ubiquitin carboxyl- terminal hydrolase 8 (usp8)
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: usp8, kiaa0055, ubpy. Expressed in: escherichia coli bl21(de3). Expression_system_taxid: 469008.
|
|
|
Chains:
A, B
(134 residues)
CATH domain:
|
|
|
|
|
|
Nmr structure of sars-cov non-structural protein nsp3a (sars1) from sars coronavirus
|
|
|
Source: Sars coronavirus tor2. Organism_taxid: 227984. Strain: tor-2. Expressed in: escherichia coli. Expression_system_taxid: 562
|
|
|
Chains:
A, B, C, D
(172 residues)
CATH domain:
|
|
|
|
|
|
De-ubiquitinating function of ataxin-3: insights from the solution structure of the josephin domain
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: atxn3, atx3, mjd, mjd1, sca3. Expressed in: escherichia coli bl21(de3). Expression_system_taxid: 469008.
|
|
|
Chain:
A
(190 residues)
CATH domains:
|
|
|
|
|
|
Crystal structure of sars-cov super complex of non-structural proteins: the hexadecamer
|
|
|
Source: Sars coronavirus. Organism_taxid: 227859. Expressed in: escherichia coli bl21(de3). Expression_system_taxid: 469008.
|
|
|
Chains:
A, B, C, D, E, F, G, H
(77 residues)
CATH domain:
|
|
|
|
|
|
X-ray structural analysis of sars coronavirus 3cl proteinase in complex with designed anti-viral inhibitors
|
|
|
Source: Sars coronavirus. Organism_taxid: 227859. Strain: sars. Expressed in: escherichia coli bl21(de3). Expression_system_taxid: 469008.
|
|
|
Chain:
A
(302 residues)
CATH domains:
|
|
|
|
|
|
Crystal structure of sars_cov mpro in complex with an inhibitor n9
|
|
|
Source: Sars coronavirus. Organism_taxid: 227859. Expressed in: escherichia coli bl21(de3). Expression_system_taxid: 469008.
|
|
|
Chains:
A, B
(309 residues)
CATH domains:
|
|
|
|
|
|
Crystal structure of porcine transmissible gastroenteritis virus mpro in complex with an inhibitor n1
|
|
|
Source: Transmissible gastroenteritis virus. Organism_taxid: 11149. Expressed in: escherichia coli bl21(de3). Expression_system_taxid: 469008.
|
|
|
Chains:
A, B
(299 residues)
CATH domains:
|
|
|
|
|
|
Crystal structure of sars_cov mpro in complex with an inhibitor n3
|
|
|
Source: Sars coronavirus. Organism_taxid: 227859. Expressed in: escherichia coli bl21(de3). Expression_system_taxid: 469008. Synthetic: yes. Synthetic construct. Organism_taxid: 32630
|
|
|
Chains:
A, B
(303 residues)
CATH domains:
|
|
|
|
|
|
Structure of usp14, a proteasome-associated deubiquitinating enzyme
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: usp14, tgt. Expressed in: escherichia coli bl21(de3). Expression_system_taxid: 469008.
|
|
|
Chains:
A, B, C
(337 residues)
CATH domain:
|
|
|
|
|
|
Structure of usp14 bound to ubquitin aldehyde
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: usp14, tgt. Expressed in: escherichia coli bl21(de3). Expression_system_taxid: 469008.
|
|
|
Chain:
A
(355 residues)
CATH domain:
|
|
|
|
|
|
Crystal structure of sars coronavirus main proteinase (p43212)
|
|
|
Source: Sars coronavirus sin2774. Organism_taxid: 235410. Gene: 1a. Expressed in: escherichia coli. Expression_system_taxid: 562.
|
|
|
Chain:
A
(300 residues)
CATH domains:
|
|
|
|
|
|
Crystal structure of sars coronavirus main proteinase (p21212)
|
|
|
Source: Sars coronavirus sin2774. Organism_taxid: 235410. Gene: 1a. Expressed in: escherichia coli. Expression_system_taxid: 562.
|
|
|
Chain:
A
(298 residues)
CATH domains:
|
|
|
|
|
|
Structure of sars cov main proteinase at 1.9 a (ph6.5)
|
|
|
Source: Sars coronavirus. Organism_taxid: 227859. Strain: sin2774. Expressed in: escherichia coli. Expression_system_taxid: 469008.
|
|
|
Chain:
A
(302 residues)
CATH domains:
|
|
|
|
|
|
Crystal structure of sars-cov mpro in complex with an inhibitor i2
|
|
|
Source: Sars coronavirus. Organism_taxid: 227859. Expressed in: escherichia coli bl21(de3). Expression_system_taxid: 469008.
|
|
|
Chains:
A, B
(301 residues)
CATH domains:
|
|
|
|
|
|
Solution structure of the first uba domain in the human ubiquitin specific protease 5 (isopeptidase 5)
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: usp5. Expressed in: cell free synthesis. Other_details: cell-free protein synthesis
|
|
|
Chain:
A
(74 residues)
CATH domain:
|
|
|
|
|
|
Solution structure of the second uba domain in the human ubiquitin specific protease 5 (isopeptidase 5)
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: usp5. Expressed in: cell free synthesis. Other_details: cell-free protein synthesis
|
|
|
Chain:
A
(63 residues)
CATH domain:
|
|
|
|
|
|
Structural basis for the recognition of lys48-linked polyubiquitin chain by the josephin domain of ataxin-3, a putative deubiquitinating enzyme
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Expressed in: escherichia coli bl21(de3). Expression_system_taxid: 469008.
|
|
|
Chain:
A
(171 residues)
CATH domains:
|
|
|
|
|
|
Crystal structure of sars coronavirus main proteinase(3clpro)
|
|
|
Source: Sars coronavirus. Organism_taxid: 227859. Other_details: cell-free protein synthesis
|
|
|
Chains:
A, B
(306 residues)
CATH domains:
|
|
|
|
|
|
Solution structure of the fourth a20-type zinc finger domain from human tumor necrosis factor, alpha-induced protein3
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: tnfaip3. Other_details: cell-free protein synthesis
|
|
|
Chain:
A
(48 residues)
|
|
|
|
|
|
Solution structure of the 7th a20-type zinc finger domain from human tumor necrosis factor, alpha-induced protein3
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: tnfaip3. Other_details: cell-free protein synthesis
|
|
|
Chain:
A
(46 residues)
|
|
|
|
|
|
Solution structure of the first a20-type zinc finger domain from human tumor necrosis factor, alpha-induced protein3
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: tnfaip3. Other_details: cell-free protein synthesis
|
|
|
Chain:
A
(49 residues)
CATH domain:
|
|
|
|
|
|
Crystal structure of ubiquitin carboxy-terminal hydrolase l1 (uch-l1)
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: uchl1. Expressed in: escherichia coli. Expression_system_taxid: 562.
|
|
|
Chains:
A, B
(223 residues)
CATH domain:
|
|
|
|
|
|
Crystal structure of the traf-like domain of hausp/usp7
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: usp7, hausp. Expressed in: escherichia coli bl21(de3). Expression_system_taxid: 469008.
|
|
|
Chain:
A
(144 residues)
CATH domain:
|
|
|
|
|
|
Crystal structure of the traf-like domain of hausp/usp7 bound to a p53 peptide
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Expressed in: escherichia coli bl21(de3). Expression_system_taxid: 469008.
|
|
|
Chains:
A, B
(137 residues)
CATH domain:
|
|
|
|
|
|
Crystal structure of the traf-like domain of hausp/usp7 bound to a mdm2 peptide
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Expressed in: escherichia coli bl21(de3). Expression_system_taxid: 469008.
|
|
|
Chain:
A
(136 residues)
CATH domain:
|
|
|
|
|
|
Crystal structure of hausp
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: usp7, hausp. Expressed in: escherichia coli bl21(de3). Expression_system_taxid: 469008.
|
|
|
Chains:
A, B
(470 residues)
CATH domains:
Unassigned
|
|
|
|
|
|
Crystal structure of sars macro domain in complex with adp-ribose at 1.8 a resolution
|
|
|
Source: Sars coronavirus. Organism_taxid: 227859. Strain: frankfurt 1. Gene: nsp3. Expressed in: escherichia coli. Expression_system_taxid: 562.
|
|
|
Chains:
A, B, C
(172 residues)
CATH domain:
|
|
|
|
|
|
Sars coronavirus papain-like protease: structure of a viral deubiquitinating enzyme
|
|
|
Source: Sars coronavirus. Organism_taxid: 227859. Strain: sars. Expressed in: escherichia coli bl21. Expression_system_taxid: 511693.
|
|
|
Chains:
A, B, C
(315 residues)
CATH domains:
|
|
|
|
|
|
The crystal structure of the n-terminal domain of hausp/usp7 complexed with p53 peptide 364-367
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: usp7, hausp. Expressed in: escherichia coli bl21(de3). Expression_system_taxid: 469008. Synthetic: yes
|
|
|
Chain:
A
(137 residues)
CATH domain:
|
|
|
|
|
|
The crystal structure of the n-terminal domain of hausp/usp7 complexed with p53 peptide 359-362
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: hausp, usp7. Expressed in: escherichia coli bl21(de3). Expression_system_taxid: 469008. Synthetic: yes
|
|
|
Chain:
A
(137 residues)
CATH domain:
|
|
|
|
|
|
The crystal structure of the n-terminal domain of hausp/usp7 complexed with mdm2 peptide 147-150
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: hausp, usp7. Expressed in: escherichia coli bl21(de3). Expression_system_taxid: 469008. Synthetic: yes
|
|
|
Chain:
A
(137 residues)
CATH domain:
|
|
|
|
|
|
Crystal structure of nsp10 from sars coronavirus
|
|
|
Source: Sars coronavirus. Organism_taxid: 227859. Strain: tor-2. Gene: orf1ab. Expressed in: escherichia coli. Expression_system_taxid: 562.
|
|
|
Chain:
A
(128 residues)
|
|
|
|
|
|
Structure of the znf ubp domain from deubiquitinating enzyme isopeptidase t (isot)
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: usp5, isot. Expressed in: escherichia coli. Expression_system_taxid: 562.
|
|
|
Chains:
A, B
(117 residues)
CATH domain:
|
|
|
|
|
|
Co-crystal structure of znf ubp domain from the deubiquitinating enzyme isopeptidase t (isot) in complex with ubiquitin
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: usp5, isot. Expressed in: escherichia coli. Expression_system_taxid: 562. Expression_system_taxid: 562
|
|
|
Chains:
A, D
(117 residues)
CATH domain:
|
|
|
|
|
|
Crystal structure of the sars coronavirus nsp10 at 2.1a
|
|
|
Source: Severe acute respiratory syndrome-related coronavirus. Organism_taxid: 694009. Expressed in: escherichia coli. Expression_system_taxid: 562.
|
|
|
Chains:
A, B, C, D, E, F, G, H, I, J, K, L, M, N, O, P, Q, R, S, T, U, V, W, X
(118 residues)
|
|
|
|
|
|
The crystal structure of sars nsp10 without zinc ion as additive
|
|
|
Source: Sars coronavirus. Organism_taxid: 227859. Expressed in: escherichia coli. Expression_system_taxid: 562.
|
|
|
Chains:
A, B, C, D, E, F, G, H, I, J, K, L, M, N, O, P, Q, R, S, T, U, V, W, X
(118 residues)
|
|
|
|
|
|
Nmr structure of the nonstructural protein 1 (nsp1) from the sars coronavirus
|
|
|
Source: Sars coronavirus. Organism_taxid: 227859. Expressed in: escherichia coli bl21(de3). Expression_system_taxid: 469008.
|
|
|
Chain:
A
(116 residues)
|
|
|
|
|
|
Structure of the catalytic domain of human ubiquitin carboxyl-terminal hydrolase 8
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: usp8, kiaa0055, ubpy. Expressed in: escherichia coli bl21. Expression_system_taxid: 511693.
|
|
|
Chain:
A
(339 residues)
CATH domain:
|
|
|
|
|
|
Nmr structure of the sars-cov non-structural protein nsp3a
|
|
|
Source: Sars coronavirus. Organism_taxid: 227859. Expressed in: escherichia coli. Expression_system_taxid: 562.
|
|
|
Chain:
A
(112 residues)
CATH domain:
|
|
|
|
|
|
Crystal structure of sars coronavirus main peptidase at ph 6.0 in the space group p21
|
|
|
Source: Sars coronavirus. Organism_taxid: 227859. Expressed in: escherichia coli. Expression_system_taxid: 562
|
|
|
Chains:
A, B
(300 residues)
CATH domains:
|
|
|
|
|
|
Crystal structure of sars coronavirus main peptidase (with an additional ala at the n-terminus of each protomer) in the space group p43212
|
|
|
Source: Sars coronavirus. Organism_taxid: 227859. Expressed in: escherichia coli. Expression_system_taxid: 562
|
|
|
Chain:
A
(298 residues)
CATH domains:
|
|
|
|
|
|
Crystal structure of sars coronavirus main peptidase (with an additional ala at the n-terminus of each protomer) inhibited by an aza-peptide epoxide in the space group p43212
|
|
|
Source: Sars coronavirus. Organism_taxid: 227859. Expressed in: escherichia coli. Expression_system_taxid: 562
|
|
|
Chain:
A
(299 residues)
CATH domains:
|
|
|
|
|
|
Crystal structure of the wildtype mhv coronavirus non-structural protein nsp15
|
|
|
Source: Murine hepatitis virus. Organism_taxid: 11142. Strain: a59. Expressed in: escherichia coli bl21(de3). Expression_system_taxid: 469008.
|
|
|
Chain:
A
(348 residues)
CATH domains:
|
|
|
|
|
|
Mutation of mhv coronavirus non-structural protein nsp15 (f307l)
|
|
|
Source: Murine hepatitis virus. Organism_taxid: 11142. Strain: a59. Expressed in: escherichia coli. Expression_system_taxid: 562.
|
|
|
Chain:
A
(348 residues)
CATH domains:
|
|
|
|
|
|
Structure of a usp8-nrdp1 complex
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: usp8, kiaa0055, ubpy. Expressed in: escherichia coli bl21. Expression_system_taxid: 511693. Gene: rnf41.
|
|
|
Chains:
A, C, E
(136 residues)
CATH domain:
|
|
|
|
|
|
Crystal structure of sars coronavirus 3cl protease inhibitor complex
|
|
|
Source: Sars coronavirus. Organism_taxid: 227859. Expressed in: escherichia coli bl21(de3). Expression_system_taxid: 469008.
|
|
|
Chain:
A
(306 residues)
CATH domains:
|
|
|
|
|
|
Structure-based drug design and structural biology study of novel nonpeptide inhibitors of sars-cov main protease
|
|
|
Source: Sars coronavirus. Organism_taxid: 227859. Strain: sars. Expressed in: escherichia coli bl21. Expression_system_taxid: 511693.
|
|
|
Chain:
A
(306 residues)
CATH domains:
|
|
|
|
|
|
Structure-based drug design and structural biology study of novel nonpeptide inhibitors of sars-cov main protease
|
|
|
Source: Sars coronavirus. Organism_taxid: 227859. Strain: sars. Expressed in: escherichia coli bl21. Expression_system_taxid: 511693.
|
|
|
Chain:
A
(306 residues)
CATH domains:
|
|
|
|
|
|
Structure-based drug design and structural biology study of novel nonpeptide inhibitors of sars-cov main protease
|
|
|
Source: Sars coronavirus. Organism_taxid: 227859. Strain: sars. Expressed in: escherichia coli bl21. Expression_system_taxid: 511693.
|
|
|
Chain:
A
(306 residues)
CATH domains:
|
|
|
|
|
|
Crystal structure of sars-cov main protease with authentic n and c- termini
|
|
|
Source: Sars coronavirus. Organism_taxid: 227859. Expressed in: escherichia coli. Expression_system_taxid: 562
|
|
|
Chain:
A
(306 residues)
CATH domains:
|
|
|
|
|
|
Crystal structure of nsp 15 from sars
|
|
|
Source: Sars coronavirus. Organism_taxid: 227859. Strain: frankfurt-1. Gene: nsp15. Expressed in: escherichia coli. Expression_system_taxid: 562.
|
|
|
Chain:
A
(347 residues)
CATH domains:
|
|
|
|
|
|
Usp2 in complex with ubiquitin
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: usp2, ubp41. Expressed in: escherichia coli. Expression_system_taxid: 562. Bos taurus. Cattle. Organism_taxid: 9913
|
|
|
Chain:
A
(315 residues)
CATH domain:
|
|
|
|
|
|
Crystal structure of sars-cov main protease with authentic n and c- termini in complex with a michael acceptor n3
|
|
|
Source: Sars coronavirus. Organism_taxid: 227859. Expressed in: escherichia coli. Expression_system_taxid: 562. Synthetic: yes. Synthetic construct. Organism_taxid: 32630
|
|
|
Chain:
A
(306 residues)
CATH domains:
|
|
|
|
|
|
Nmr structure of the nonstructural protein 1 (nsp1) from the sars coronavirus
|
|
|
Source: Sars coronavirus. Organism_taxid: 227859. Expressed in: escherichia coli bl21(de3). Expression_system_taxid: 469008.
|
|
|
Chain:
A
(116 residues)
|
|
|
|
|
|
Solution structure of ubp-m znf-ubp domain
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: usp16. Expressed in: escherichia coli bl21(de3). Expression_system_taxid: 469008.
|
|
|
Chain:
A
(122 residues)
CATH domain:
|
|
|
|
|
|
Covalent ubiquitin-usp2 complex
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: usp2, ubp41. Expressed in: escherichia coli bl21(de3). Expression_system_taxid: 469008. Gene: rps27a, uba52, ubb, ubc.
|
|
|
Chain:
A
(335 residues)
CATH domain:
|
|
|
|
|
|
Nmr structure of the sars-cov non-structural protein nsp3a
|
|
|
Source: Sars coronavirus. Organism_taxid: 227859. Expressed in: escherichia coli. Expression_system_taxid: 562.
|
|
|
Chain:
A
(112 residues)
CATH domain:
|
|
|
|
|
|
Human coronavirus 229e non structural protein 9 (nsp9)
|
|
|
Source: Human coronavirus 229e. Hcov 229e. Organism_taxid: 11137. Expressed in: escherichia coli. Expression_system_taxid: 562
|
|
|
Chain:
A
(98 residues)
CATH domain:
|
|
|
|
|
|
Human coronavirus 229e non structural protein 9 cys69ala mutant (nsp9)
|
|
|
Source: Human coronavirus 229e. Hcov 229e. Organism_taxid: 11137. Expressed in: escherichia coli. Expression_system_taxid: 562. Expression_system_taxid: 562
|
|
|
Chains:
A, B
(106 residues)
CATH domain:
|
|
|
|
|
|
Solution structure of the josephin domain of ataxin-3 in complex with ubiquitin molecule.
|
|
|
Source: Homo sapiens. Human. Gene: atxn3, atx3, mjd, mjd1, sca3. Expressed in: escherichia coli. Expression_system_variant: de3. Gene: ubc.
|
|
|
Chain:
A
(182 residues)
CATH domains:
|
|
|
|
|
|
Nmr structure of the domain 527-651 of the sars-cov nonstructural protein nsp3
|
|
|
Source: Sars coronavirus. Organism_taxid: 227859. Gene: rep, 1a-1b. Expressed in: escherichia coli bl21(de3). Expression_system_taxid: 469008.
|
|
|
Chain:
A
(129 residues)
CATH domain:
|
|
|
|
|
|
Nmr structure of the domain 527-651 of the sars-cov nonstructural protein nsp3, single conformer closest to the mean coordinates of an ensemble of twenty energy minimized conformers
|
|
|
Source: Sars coronavirus. Organism_taxid: 227859. Gene: rep, 1a-1b. Expressed in: escherichia coli bl21(de3). Expression_system_taxid: 469008.
|
|
|
Chain:
A
(129 residues)
CATH domain:
|
|
|
|
|
|
Nmr conformer closest to the mean coordinates of the domain 513-651 of the sars-cov nonstructural protein nsp3
|
|
|
Source: Sars coronavirus. Organism_taxid: 227859. Gene: rep, 1a-1b. Expressed in: escherichia coli bl21(de3). Expression_system_taxid: 469008.
|
|
|
Chain:
A
(143 residues)
CATH domain:
|
|
|
|
|
|
Solution structure of c-terminal domain of sars-cov main protease
|
|
|
Source: Sars coronavirus. Organism_taxid: 255730. Expressed in: escherichia coli. Expression_system_taxid: 562.
|
|
|
Chain:
A
(120 residues)
CATH domain:
|
|
|
|
|
|
Nmr structure of a putative RNA binding protein (sars1) from sars coronavirus
|
|
|
Source: Sars coronavirus. Sars-cov. Organism_taxid: 227859. Gene: 1a. Expressed in: escherichia coli. Expression_system_taxid: 562.
|
|
|
Chain:
A
(116 residues)
CATH domain:
|
|
|
|
|
|
Solution structure of the sars-unique domain-c from the nonstructural protein 3 (nsp3) of the severe acute respiratory syndrome coronavirus
|
|
|
Source: Sars coronavirus. Sars-cov. Organism_taxid: 227859. Gene: 1a. Expressed in: escherichia coli. Expression_system_taxid: 562.
|
|
|
Chain:
A
(67 residues)
CATH domain:
|
|
|
|
|
|
Solution structure of the tandem uim domain of ataxin-3 complexed with ubiquitin
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Expressed in: escherichia coli. Expression_system_taxid: 562.
|
|
|
Chain:
A
(46 residues)
|
|
|
|
|
|
Sars coronavirus-unique domain (sud): three-domain molecular architecture in solution and RNA binding. I: structure of the sud-m domain of sud-mc
|
|
|
Source: Sars coronavirus. Organism_taxid: 227859. Strain: tor2. Gene: 1a. Expressed in: escherichia coli. Expression_system_taxid: 562.
|
|
|
Chain:
A
(129 residues)
CATH domain:
|
|
|
|
|
|
Sars coronavirus-unique domain (sud): three-domain molecular architecture in solution and RNA binding. Ii: structure of the sud-c domain of sud-mc
|
|
|
Source: Sars coronavirus. Organism_taxid: 227859. Strain: tor2. Gene: 1a. Expressed in: escherichia coli. Expression_system_taxid: 562.
|
|
|
Chain:
A
(67 residues)
CATH domain:
|
|
|
|
|
|
Solution nmr structure of human ubiquitin specific protease usp7 ubl domain (residues 537-664). Nesg target hr4395c/ sgc-toronto
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: usp7, hausp. Expressed in: escherichia coli. Expression_system_taxid: 562.
|
|
|
Chain:
A
(128 residues)
|
|
|
|
|
|
Nmr structure of the sars coronavirus nonstructural protein nsp7 in solution at ph 6.5
|
|
|
Source: Sars coronavirus. Organism_taxid: 227859. Strain: tor2. Gene: 1a. Expressed in: escherichia coli. Expression_system_taxid: 469008.
|
|
|
Chain:
A
(85 residues)
|
|
|
|
|
|
Solution nmr structure of ubiquitin thioesterase otu1 (ec 3.1.2.-) From mus musculus, northeast structural genomics consortium target mmt2a
|
|
|
Source: Mus musculus. Mouse. Organism_taxid: 10090. Gene: yod1. Expressed in: escherichia coli. Expression_system_taxid: 469008.
|
|
|
Chain:
A
(86 residues)
CATH domain:
|
|
|
|
|
|
Solution nmr structure of human uba-like domain of otud7a_11_83, nesg target ht6304a/ocsp target otud7a_11_83/sgc-toronto
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: otud7a, c15orf16, cezanne2, otud7. Expressed in: escherichia coli. Expression_system_taxid: 562.
|
|
|
Chain:
A
(73 residues)
CATH domain:
|
|
|
|
|
|
Solution structure of the zinc finger domain of usp13
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: usp13. Expressed in: escherichia coli. Expression_system_taxid: 469008.
|
|
|
Chain:
A
(114 residues)
CATH domain:
|
|
|
|
|
|
Nmr structure of the arterivirus nonstructural protein 7 alpha (nsp7 alpha)
|
|
|
Source: Equine arteritis virus. Eav. Organism_taxid: 299386. Strain: bucyrus. Gene: rep, 1a-1b. Expressed in: escherichia coli. Expression_system_taxid: 562.
|
|
|
Chain:
A
(123 residues)
CATH domain:
|
|
|
|
|
|
Solution structure of tandem uba of usp13
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: usp13, isot3. Expressed in: escherichia coli. Expression_system_taxid: 562.
|
|
|
Chain:
A
(126 residues)
CATH domains:
|
|
|
|
|
|
Solution structure of uchl1 s18y variant
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: uchl1. Expressed in: escherichia coli. Expression_system_taxid: 562.
|
|
|
Chain:
A
(231 residues)
CATH domain:
|
|
|
|
|
|
Nmr solution structure of c-terminal domain of sars-cov main protease in 2.5m urea
|
|
|
Source: Sars coronavirus. Sars-cov. Organism_taxid: 227859. Gene: 1a. Expressed in: escherichia coli. Expression_system_taxid: 562.
|
|
|
Chain:
A
(120 residues)
CATH domain:
|
|
|
|
|
|
Nmr solution structure of the n-terminal domain of human usp28, northeast structural genomics consortium target ht8470a
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: usp28, kiaa1515. Expressed in: escherichia coli. Expression_system_taxid: 562.
|
|
|
Chain:
A
(111 residues)
CATH domains:
|
|
|
|
|
|
Solution structure of mhv nsp3a
|
|
|
Source: Murine hepatitis virus. Organism_taxid: 11142. Strain: a59. Gene: 1a. Expressed in: escherichia coli. Expression_system_taxid: 562.
|
|
|
Chain:
A
(114 residues)
CATH domain:
|
|
|
|
|
|
The proteolytic activity of ubiquitin-specific protease 28 is modulated by the n-terminal domain
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: usp28, kiaa1515. Expressed in: escherichia coli. Expression_system_taxid: 562.
|
|
|
Chain:
A
(120 residues)
|
|
|
|
|
|
Sumo2 non-covalently interacts with usp25 and downregulates its activity
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: usp25, usp21. Expressed in: escherichia coli. Expression_system_taxid: 562.
|
|
|
Chain:
A
(146 residues)
|
|
|
|
|
|
Ubx-l domain of vcip135
|
|
|
Source: Rattus norvegicus. Norway rat. Organism_taxid: 10116. Gene: vcpip1, vcip135. Expressed in: escherichia coli. Expression_system_taxid: 562.
|
|
|
Chain:
A
(81 residues)
CATH domain:
|
|
|
|
|
|
Substrate specificity profiling and identification of a new class of inhibitor for the major protease of the sars coronavirus
|
|
|
Source: Sars coronavirus. Organism_taxid: 227859. Strain: tor2. Gene: 3clpro. Expressed in: escherichia coli bl21(de3). Expression_system_taxid: 469008.
|
|
|
Chains:
A, B
(302 residues)
CATH domains:
|
|
|
|
|
|
Structure of an n-terminal truncated form of nendou (nsp15) from sars- coronavirus
|
|
|
Source: Sars coronavirus. Organism_taxid: 227859. Strain: tor-2. Expressed in: escherichia coli. Expression_system_taxid: 562.
|
|
|
Chains:
A, B, C, D
(306 residues)
CATH domains:
Unassigned
|
|
|
|
|
|
Crystal structure of g11a mutant of sars-cov 3c-like protease
|
|
|
Source: Sars coronavirus. Organism_taxid: 228407. Strain: bj01. Gene: rep. Expressed in: escherichia coli bl21. Expression_system_taxid: 511693.
|
|
|
Chain:
A
(289 residues)
CATH domains:
|
|
|
|
|
|
Crystal structure of infectious bronchitis virus (ibv) main protease
|
|
|
Source: Infectious bronchitis virus. Organism_taxid: 11120. Strain: m41. Gene: m41 3c-like protease gene. Expressed in: escherichia coli bl21. Expression_system_taxid: 511693.
|
|
|
Chains:
A, B, C
(296 residues)
CATH domains:
|
|
|
|
|
|
Crystal structure of infectious bronchitis virus (ibv) main protease in complex with a michael acceptor inhibitor n3
|
|
|
Source: Infectious bronchitis virus. Organism_taxid: 11120. Strain: m41. Gene: m41 3c-like protease gene. Expressed in: escherichia coli bl21. Expression_system_taxid: 511693. Synthetic: yes. Synthetic construct. Organism_taxid: 32630
|
|
|
Chains:
A, B
(294 residues)
CATH domains:
|
|
|
|
|
|
Crystal structure of sars-cov main protease h41a mutant in complex with an n-terminal substrate
|
|
|
Source: Sars coronavirus. Organism_taxid: 228407. Strain: bj01. Gene: rep. Expressed in: escherichia coli bl21. Expression_system_taxid: 511693. Synthetic: yes. Other_details: chemically synthesized.
|
|
|
Chains:
A, B, C
(305 residues)
CATH domains:
|
|
|
|
|
|
Crystal structure of severe acute respiratory syndrome (sars) 3c-like protease asn214ala mutant
|
|
|
Source: Sars coronavirus. Virus. Gene: rep. Expressed in: escherichia coli.
|
|
|
Chains:
A, B
(305 residues)
CATH domains:
|
|
|
|
|
|
Crystal structure of a monomeric form of severe acute respiratory syndrome (sars) 3c-like protease mutant
|
|
|
Source: Sars coronavirus. Organism_taxid: 227859. Gene: rep. Expressed in: escherichia coli bl21(de3). Expression_system_taxid: 469008.
|
|
|
Chain:
A
(306 residues)
CATH domains:
|
|
|
|
|
|
Structure-based design and synthesis and biological evaluation of peptidomimetic sars-3clpro inhibitors
|
|
|
Source: Sars coronavirus. Organism_taxid: 227859. Gene: rep. Expressed in: escherichia coli. Expression_system_taxid: 562
|
|
|
Chain:
A
(301 residues)
CATH domains:
|
|
|
|
|
|
Yeast deubiquitinase ubp3 and bre5 cofactor complex
|
|
|
Source: Saccharomyces cerevisiae. Baker's yeast. Organism_taxid: 4932. Gene: bre5. Expressed in: escherichia coli bl21(de3). Expression_system_taxid: 469008. Gene: ubp3.
|
|
|
Chains:
C, D
(25 residues)
|
|
|
|
|
|
Crystal structure of nsp15-h234a mutant- hexamer in asymmetric unit
|
|
|
Source: Sars coronavirus. Organism_taxid: 227859. Strain: urbani isolate of sars-cov. Gene: nsp15. Expressed in: escherichia coli. Expression_system_taxid: 562. Expression_system_cell_line: bl21 star.
|
|
|
Chains:
A, B, C, D, E, F
(345 residues)
CATH domains:
|
|
|
|
|
|
Nmr structure of the domain 513-651 of the sars-cov nonstructural protein nsp3
|
|
|
Source: Sars coronavirus. Organism_taxid: 227859. Gene: rep, 1a-1b. Expressed in: escherichia coli bl21(de3). Expression_system_taxid: 469008.
|
|
|
Chain:
A
(143 residues)
CATH domain:
|
|
|
|
|
|
Zf-ubp domain of vdu1
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Expressed in: escherichia coli bl21(de3). Expression_system_taxid: 469008. Expression_system_variant: c41.
|
|
|
Chain:
A
(95 residues)
CATH domain:
|
|
|
|
|
|
Crystal structures of the sars-coronavirus main proteinase inactivated by benzotriazole compounds
|
|
|
Source: Human sars coronavirus. Sars-cov. Organism_taxid: 227859. Expressed in: escherichia coli. Expression_system_taxid: 469008.
|
|
|
Chain:
A
(306 residues)
CATH domains:
|
|
|
|
|
|
Structure of the a20 ovarian tumour (otu) domain
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Expressed in: escherichia coli. Expression_system_taxid: 469008.
|
|
|
Chains:
A, B, C, D
(330 residues)
|
|
|
|
|
|
Structure of the cyld usp domain
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Expressed in: spodoptera frugiperda. Expression_system_taxid: 7108. Expression_system_cell_line: sf9.
|
|
|
Chains:
A, B
(341 residues)
CATH domain:
|
|
|
|
|
|
A structural view of the inactivation of the sars-coronavirus main proteinase by benzotriazole esters
|
|
|
Source: Human sars coronavirus. Organism_taxid: 227859. Expressed in: escherichia coli. Expression_system_taxid: 562
|
|
|
Chains:
A, B
(300 residues)
CATH domains:
|
|
|
|
|
|
Structure of the nsp3 x-domain of human coronavirus nl63
|
|
|
Source: Human coronavirus nl63. Hcov-nl63. Organism_taxid: 277944. Expressed in: escherichia coli. Expression_system_taxid: 469008.
|
|
|
Chain:
A
(173 residues)
CATH domain:
|
|
|
|
|
|
Human sars coronavirus unique domain
|
|
|
Source: Sars coronavirus. Organism_taxid: 227859. Expressed in: escherichia coli. Expression_system_taxid: 562
|
|
|
Chains:
A, B
(257 residues)
CATH domains:
|
|
|
|
|
|
Human sars coronavirus unique domain (triclinic form)
|
|
|
Source: Sars coronavirus. Organism_taxid: 227859. Strain: sars-cov. Expressed in: escherichia coli. Expression_system_taxid: 562.
|
|
|
Chains:
A, B, C, D
(257 residues)
CATH domains:
|
|
|
|
|
|
Crystal structure of plasmodium falciparum uchl3 in complex with the suicide inhibitor ubvme
|
|
|
Source: Plasmodium falciparum. Malaria parasite. Organism_taxid: 5833. Strain: clone 3d7. Expressed in: escherichia coli. Expression_system_taxid: 469008. Homo sapiens. Human. Organism_taxid: 9606.
|
|
|
Chains:
A, C
(204 residues)
CATH domains:
|
|
|
|
|
|
Crystal structure of plasmodium falciparum ubiquitin carboxyl- terminal hydrolase 3 (uchl3)
|
|
|
Source: Plasmodium falciparum. Malaria parasite. Organism_taxid: 5833. Strain: clone 3d7. Expressed in: escherichia coli. Expression_system_taxid: 469008.
|
|
|
Chains:
A, B
(208 residues)
CATH domains:
|
|
|
|
|
|
Structure of the virf4-hausp traf domain complex
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Expressed in: escherichia coli. Expression_system_taxid: 562. Human herpesvirus 8. Organism_taxid: 37296. Expression_system_taxid: 562
|
|
|
Chain:
A
(143 residues)
CATH domain:
|
|
|
|
|
|
Crystal structure of the nsp16 nsp10 sars coronavirus complex
|
|
|
Source: Sars coronavirus. Organism_taxid: 227859. Expressed in: escherichia coli bl21(de3). Expression_system_taxid: 469008. Expression_system_variant: c41. Expression_system_variant: c41
|
|
|
Chains:
A, B
(287 residues)
CATH domain:
|
|
|
|
|
|
Crystal structure of the nsp16 nsp10 sars coronavirus complex
|
|
|
Source: Sars coronavirus. Organism_taxid: 227859. Expressed in: escherichia coli bl21(de3). Expression_system_taxid: 469008. Expression_system_variant: c41. Expression_system_variant: c41
|
|
|
Chains:
A, B
(286 residues)
CATH domain:
|
|
|
|
|
|
Crystal structure of the nsp16 nsp10 sars coronavirus complex
|
|
|
Source: Sars coronavirus. Organism_taxid: 227859. Expressed in: escherichia coli bl21(de3). Expression_system_taxid: 469008. Expression_system_variant: c41. Expression_system_variant: c41
|
|
|
Chains:
A, B
(285 residues)
CATH domain:
|
|
|
|
|
|
Structure of usp21 in complex with linear diubiquitin-aldehyde
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Expressed in: escherichia coli. Expression_system_taxid: 562.
|
|
|
Chains:
A, E
(315 residues)
CATH domain:
|
|
|
|
|
|
Structure of the d1d2 domain of usp4, the conserved catalytic domain
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Expressed in: escherichia coli. Expression_system_taxid: 562.
|
|
|
Chains:
A, B, C, D, E, F
(337 residues)
CATH domain:
|
|
|
|
|
|
Mechanism of usp7 (hausp) activation by its c-terminal ubiquitin-like domain (hubl) and allosteric regulation by gmp-synthetase.
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Expressed in: escherichia coli. Expression_system_taxid: 469008.
|
|
|
Chain:
A
(529 residues)
CATH domains:
Unassigned
|
|
|
|
|
|
Crystal structure of the main protease of coronavirus hku4
|
|
|
Source: Tylonycteris bat coronavirus hku4. Organism_taxid: 694007. Strain: hku4-1l. Expressed in: escherichia coli. Expression_system_taxid: 469008. Expression_system_variant: gold
|
|
|
Chains:
A, B
(306 residues)
CATH domains:
|
|
|
|
|
|
Crystal structure of the main protease of coronavirus hku4 in complex with a michael acceptor sg85
|
|
|
Source: Tylonycteris bat coronavirus hku4. Organism_taxid: 694007. Strain: hku4-1. Expressed in: escherichia coli. Expression_system_taxid: 469008. Expression_system_variant: gold
|
|
|
Chains:
A, B
(306 residues)
CATH domains:
|
|
|
|
|
|
A mechanistic view of enzyme inhibition and peptide hydrolysis in the active site of the sars-cov 3c-like peptidase
|
|
|
Source: Sars coronavirus. Organism_taxid: 227859. Gene: rep. Expressed in: escherichia coli. Expression_system_taxid: 562. Synthetic: yes. Synthetic construct. Organism_taxid: 32630
|
|
|
Chain:
A
(306 residues)
CATH domains:
|
|
|
|
|
|
A mechanistic view of enzyme inhibition and peptide hydrolysis in the active site of the sars-cov 3c-like peptidase
|
|
|
Source: Sars coronavirus. Sars-cov. Organism_taxid: 227859. Gene: rep. Expressed in: escherichia coli. Expression_system_taxid: 562. Synthetic: yes. Other_details: the peptide was chemically synthesized.
|
|
|
Chain:
A
(306 residues)
CATH domains:
|
|
|
|
|
|
A mechanistic view of enzyme inhibition and peptide hydrolysis in the active site of the sars-cov 3c-like peptidase
|
|
|
Source: Sars coronavirus. Organism_taxid: 227859. Gene: rep. Expressed in: escherichia coli. Expression_system_taxid: 562. Synthetic: yes. Other_details: the peptide was chemically synthesized.
|
|
|
Chain:
A
(306 residues)
CATH domains:
|
|
|
|
|
|
Complex structure of sars-cov 3c-like protease with tdt
|
|
|
Source: Sars coronavirus. Organism_taxid: 227859. Expressed in: escherichia coli. Expression_system_taxid: 562.
|
|
|
Chain:
A
(306 residues)
CATH domains:
|
|
|
|
|
|
Complex structure of sars-cov 3c-like protease with pma
|
|
|
Source: Sars coronavirus. Organism_taxid: 227859. Expressed in: escherichia coli. Expression_system_taxid: 562
|
|
|
Chain:
A
(306 residues)
CATH domains:
|
|
|
|
|
|
Complex structure of sars-cov 3c-like protease with epdtc
|
|
|
Source: Sars coronavirus. Organism_taxid: 227859. Expressed in: escherichia coli. Expression_system_taxid: 562
|
|
|
Chains:
A, B
(302 residues)
CATH domains:
|
|
|
|
|
|
Complex structure of sars-cov 3c-like protease with jmf1600
|
|
|
Source: Sars coronavirus. Organism_taxid: 227859. Expressed in: escherichia coli. Expression_system_taxid: 562
|
|
|
Chains:
A, B
(305 residues)
CATH domains:
|
|
|
|
|
|
Complex structure of sars-cov 3c-like protease with jmf1586
|
|
|
Source: Sars coronavirus. Organism_taxid: 227859. Expressed in: escherichia coli. Expression_system_taxid: 562
|
|
|
Chains:
A, B
(300 residues)
CATH domains:
|
|
|
|
|
|
Crystal structure of human otubain 1
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: otub1, otb1, otu1. Expressed in: escherichia coli bl21(de3). Expression_system_taxid: 469008.
|
|
|
Chain:
A
(226 residues)
CATH domains:
|
|
|
|
|
|
Complex structure of cov 229e 3cl protease with epdtc
|
|
|
Source: Human coronavirus. Hcov-229e. Organism_taxid: 11137. Strain: 229e. Expressed in: escherichia coli. Expression_system_taxid: 562.
|
|
|
Chains:
A, B
(300 residues)
CATH domains:
|
|
|
|
|
|
Complex structure of sars-cov 3cl protease with tg-0204998
|
|
|
Source: Sars coronavirus. Sars-cov. Organism_taxid: 227859. Expressed in: escherichia coli. Expression_system_taxid: 562.
|
|
|
Chain:
A
(306 residues)
CATH domains:
|
|
|
|
|
|
Complex structure of sars-cov 3cl protease with tg-0205486
|
|
|
Source: Sars coronavirus. Sars-cov. Organism_taxid: 227859. Expressed in: escherichia coli. Expression_system_taxid: 562.
|
|
|
Chain:
A
(306 residues)
CATH domains:
|
|
|
|
|
|
Catalytic domain of uch37
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: uch37. Expressed in: escherichia coli. Expression_system_taxid: 562.
|
|
|
Chain:
A
(204 residues)
CATH domain:
|
|
|
|
|
|
Structure-based design, synthesis, evaluation of peptide-mimetic sars 3cl protease inhibitors
|
|
|
Source: Sars coronavirus. Sars-cov. Organism_taxid: 227859. Gene: 1a. Expressed in: escherichia coli. Expression_system_taxid: 562. Synthetic: yes. Other_details: the peptide was designed and chemically synthesized.
|
|
|
Chains:
A, B
(300 residues)
CATH domains:
|
|
|
|
|
|
Structure of sars 3cl protease with peptidic aldehyde inhibitor containing cyclohexyl side chain
|
|
|
Source: Sars coronavirus. Sars-cov. Organism_taxid: 227859. Gene: 1a. Expressed in: escherichia coli. Expression_system_taxid: 562. Synthetic: yes. Other_details: the peptide was chemically synthesized.
|
|
|
Chain:
A
(300 residues)
CATH domains:
|
|
|
|
|
|
Structure of sars 3cl protease with peptidic aldehyde inhibitor
|
|
|
Source: Sars coronavirus. Sars-cov. Organism_taxid: 227859. Gene: 1a. Expressed in: escherichia coli. Expression_system_taxid: 562. Synthetic: yes. Other_details: the peptide was chemically synthesized.
|
|
|
Chain:
A
(306 residues)
CATH domains:
|
|
|
|
|
|
Structure of sars 3cl protease auto-proteolysis resistant mutant in the absent of inhibitor
|
|
|
Source: Sars coronavirus. Sars-cov. Organism_taxid: 227859. Gene: 1a. Expressed in: escherichia coli. Expression_system_taxid: 562.
|
|
|
Chains:
A, B
(301 residues)
CATH domains:
|
|
|
|
|
|
Structure of ovarian tumor (otu) domain in complex with ubiquitin
|
|
|
Source: Saccharomyces cerevisiae. Baker's yeast. Organism_taxid: 4932. Gene: otu1. Expressed in: escherichia coli bl21(de3). Expression_system_taxid: 469008. Homo sapiens. Human. Organism_taxid: 9606.
|
|
|
Chain:
A
(172 residues)
CATH domain:
|
|
|
|
|
|
Structure of ovarian tumor (otu) domain in complex with ubiquitin
|
|
|
Source: Saccharomyces cerevisiae. Baker's yeast. Organism_taxid: 4932. Gene: otu1. Expressed in: escherichia coli bl21(de3). Expression_system_taxid: 469008. Homo sapiens. Human. Organism_taxid: 9606.
|
|
|
Chains:
A, C
(175 residues)
CATH domain:
|
|
|
|
|
|
Structure of seneca valley virus-001
|
|
|
Source: Seneca valley virus. Organism_taxid: 390157. Organism_taxid: 390157
|
|
|
Chains:
A, B, C, D
(258 residues)
CATH domain:
|
|
|
|
|
|
Main protease of hcov-hku1
|
|
|
Source: Human coronavirus. Hcov-hku1. Organism_taxid: 443239. Strain: hku1. Gene: rep. Expressed in: escherichia coli. Expression_system_taxid: 562. Synthetic: yes. Synthetic construct.
|
|
|
Chains:
B, A, C, D
(301 residues)
CATH domains:
|
|
|
|
|
|
Development of broad-spectrum halomethyl ketone inhibitors against coronavirus main protease 3clpro
|
|
|
Source: Sars coronavirus. Organism_taxid: 227859. Gene: rep. Expressed in: escherichia coli. Expression_system_taxid: 562.
|
|
|
Chain:
A
(299 residues)
CATH domains:
|
|
|
|
|
|
Crystal structure of a20, 2.5 angstrom
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: tnfaip3. Expressed in: escherichia coli.
|
|
|
Chains:
A, B, C, D, E, F
(352 residues)
|
|
|
|
|
|
Crystal structure of sars-cov mpro mutant in p21 at ph6.9
|
|
|
Source: Sars coronavirus. Sars-cov. Organism_taxid: 227859. Expressed in: escherichia coli bl21. Expression_system_taxid: 511693.
|
|
|
Chains:
A, B
(305 residues)
CATH domains:
|
|
|
|
|
|
A new class of papain-like protease/deubiquitinase inhibitors blocks sars virus replication
|
|
|
Source: Sars coronavirus. Sars-cov. Organism_taxid: 227859. Gene: 1a. Expressed in: escherichia coli. Expression_system_taxid: 562
|
|
|
Chain:
A
(317 residues)
CATH domains:
|
|
|
|
|
|
Crystal structure of sars-cov main protease triple mutant sti/a in space group p21
|
|
|
Source: Sars coronavirus. Sars-cov. Organism_taxid: 227859. Expressed in: escherichia coli. Expression_system_taxid: 562.
|
|
|
Chains:
A, B
(305 residues)
CATH domains:
|
|
|
|
|
|
Crystal structure of sars-cov main protease triple mutant sti/a in space group c2
|
|
|
Source: Sars coronavirus. Sars-cov. Organism_taxid: 227859. Expressed in: escherichia coli. Expression_system_taxid: 562.
|
|
|
Chain:
A
(306 residues)
CATH domains:
|
|
|
|
|
|
Crystal structure of sars-cov main protease quadruple mutant stif/a with one molecule in one asymmetric unit
|
|
|
Source: Sars coronavirus. Sars-cov. Organism_taxid: 227859. Expressed in: escherichia coli. Expression_system_taxid: 562.
|
|
|
Chain:
A
(301 residues)
CATH domains:
|
|
|
|
|
|
Crystal structure of sars-cov main protease quadruple mutant stif/a with two molecules in one asymmetric unit
|
|
|
Source: Sars coronavirus. Sars-cov. Organism_taxid: 227859. Expressed in: escherichia coli. Expression_system_taxid: 562.
|
|
|
Chains:
A, B
(302 residues)
CATH domains:
|
|
|
|
|
|
A special dimerization of sars-cov main proteasE C-terminal domain due to domain-swapping
|
|
|
Source: Sars coronavirus. Sars-cov. Organism_taxid: 227859. Gene: rep, 1a-1b. Expressed in: escherichia coli. Expression_system_taxid: 562.
|
|
|
Chains:
A, B, C, D
(100 residues)
CATH domain:
|
|
|
|
|
|
Crystal structure of sars-cov nsp9 g104e
|
|
|
Source: Sars coronavirus. Sars-cov. Organism_taxid: 227859. Strain: urbani. Gene: 1a. Expressed in: escherichia coli. Expression_system_taxid: 562.
|
|
|
Chains:
A, B, C, D
(106 residues)
CATH domain:
|
|
|
|
|
|
Crystal structure of ibv x-domain at ph 8.5
|
|
|
Source: Avian infectious bronchitis virus (strain beaudette). Ibv. Organism_taxid: 11120. Gene: 1a. Expressed in: escherichia coli. Expression_system_taxid: 562.
|
|
|
Chain:
A
(166 residues)
CATH domain:
|
|
|
|
|
|
Crystal structure of hcov-229e x-domain
|
|
|
Source: Human coronavirus 229e. Hcov-229e. Organism_taxid: 11137. Gene: 1a. Expressed in: escherichia coli. Expression_system_taxid: 562.
|
|
|
Chain:
A
(165 residues)
CATH domain:
|
|
|
|
|
|
Crystal structure of ibv x-domain at ph 5.6
|
|
|
Source: Avian infectious bronchitis virus (strain beaudette). Ibv. Organism_taxid: 11122. Gene: rep, 1a-1b. Expressed in: escherichia coli. Expression_system_taxid: 562.
|
|
|
Chain:
A
(171 residues)
CATH domain:
|
|
|
|
|
|
Structure of a cubic crystal form of x (adrp) domain from fcov
|
|
|
Source: Feline infectious peritonitis virus. Fcov. Organism_taxid: 33734. Strain: fipv wsu-79/1146. Expressed in: escherichia coli. Expression_system_taxid: 562.
|
|
|
Chains:
A, B, C, D, E, F, G, H
(168 residues)
CATH domain:
|
|
|
|
|
|
Structure of the tetragonal crystal form of x (adrp) domain from fcov
|
|
|
Source: Feline infectious peritonitis virus. Fcov. Organism_taxid: 33734. Strain: fipv wsu-79/1146. Expressed in: escherichia coli. Expression_system_taxid: 562
|
|
|
Chains:
A, B, C
(168 residues)
CATH domain:
|
|
|
|
|
|
Ibv nsp3 adrp domain
|
|
|
Source: Avian infectious bronchitis virus. Ibv. Gene: 1a. Expressed in: escherichia coli. Expression_system_taxid: 562.
|
|
|
Chains:
A, B
(177 residues)
CATH domain:
|
|
|
|
|
|
Complex of substrate adp-ribose with ibv nsp3 adrp domain
|
|
|
Source: Avian infectious bronchitis virus. Ibv. Gene: 1a. Expressed in: escherichia coli. Expression_system_taxid: 562.
|
|
|
Chains:
A, B
(177 residues)
CATH domain:
|
|
|
|
|
|
Hcov-229e nsp3 adrp domain
|
|
|
Source: Human coronavirus 229e. Hcov-229e. Organism_taxid: 11137. Gene: 1a. Expressed in: escherichia coli. Expression_system_taxid: 562.
|
|
|
Chain:
A
(167 residues)
CATH domain:
|
|
|
|
|
|
Complex of substrate adp-ribose with hcov-229e nsp3 adrp domain
|
|
|
Source: Human coronavirus 229e. Hcov-229e. Organism_taxid: 11137. Expressed in: escherichia coli. Expression_system_taxid: 562.
|
|
|
Chain:
A
(167 residues)
CATH domain:
|
|
|
|
|
|
Crystal structure of the s139a mutant of sars-coronovirus 3c-like protease
|
|
|
Source: Sars coronavirus. Sars-cov. Organism_taxid: 227859. Strain: bj01. Gene: 1a. Expressed in: escherichia coli. Expression_system_taxid: 562.
|
|
|
Chain:
A
(297 residues)
CATH domains:
|
|
|
|
|
|
Crystal structure of the f140a mutant of sars-coronovirus 3c-like protease at ph 6.0
|
|
|
Source: Sars coronavirus. Sars-cov. Organism_taxid: 227859. Strain: bj01. Gene: 1a. Expressed in: escherichia coli. Expression_system_taxid: 562.
|
|
|
Chains:
A, B
(299 residues)
CATH domains:
|
|
|
|
|
|
Crystal structure of the f140a mutant of sars-coronovirus 3c-like protease at ph 6.5
|
|
|
Source: Sars coronavirus. Sars-cov. Organism_taxid: 227859. Strain: bj01. Gene: 1a. Expressed in: escherichia coli. Expression_system_taxid: 562.
|
|
|
Chains:
A, B
(297 residues)
CATH domains:
|
|
|
|
|
|
Crystal structure of the f140a mutant of sars-coronovirus 3c-like protease at ph 7.6
|
|
|
Source: Sars coronavirus. Sars-cov. Organism_taxid: 227859. Strain: bj01. Gene: 1a. Expressed in: escherichia coli. Expression_system_taxid: 562.
|
|
|
Chains:
A, B
(299 residues)
CATH domains:
|
|
|
|
|
|
Crystal structure of chymotrypsin-like protease/proteinase (3clsp/nsp4) of porcine reproductive and respiratory syndrome virus (prrsv)
|
|
|
Source: Porcine respiratory and reproductive syndrome virus. Prrsv. Organism_taxid: 28344. Strain: jxa1. Gene: nsp4, orf1a. Expressed in: escherichia coli. Expression_system_taxid: 562.
|
|
|
Chain:
A
(192 residues)
CATH domains:
|
|
|
|
Bound ligand:
|
Het Group PO4
corresponds to
enzyme product phosphate
|
|
|
|
|
|
|
Crystal structure of s118a mutant 3clsp of prrsv
|
|
|
Source: Porcine respiratory and reproductive syndrome virus. Prrsv. Organism_taxid: 28344. Strain: jxa1. Gene: nsp4, orf1a. Expressed in: escherichia coli. Expression_system_taxid: 562.
|
|
|
Chain:
A
(192 residues)
CATH domains:
|
|
|
|
Bound ligand:
|
Het Group PO4
corresponds to
enzyme product phosphate
|
|
|
|
|
|
|
Mutation of asn28 disrupts the enzymatic activity and dimerization of sars 3clpro
|
|
|
Source: Sars coronavirus. Virus. Organism_taxid: 227859. Strain: tor2. Gene: 1a, sars 3cl protease. Expressed in: escherichia coli. Expression_system_taxid: 562.
|
|
|
Chain:
A
(296 residues)
CATH domains:
|
|
|
|
|
|
Structure of thE C-terminal domain of nsp4 from feline coronavirus
|
|
|
Source: Feline coronavirus. Organism_taxid: 12663. Strain: fipv wsu-79. Expressed in: escherichia coli bl21(de3). Expression_system_taxid: 469008.
|
|
|
Chains:
A, B, C, D, E
(96 residues)
CATH domain:
|
|
|
|
|
|
Crystal structure of covalent ubiquitin-usp21 complex
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: pp1490, usp21, usp23. Expressed in: escherichia coli. Expression_system_taxid: 562. Gene: rps27a, uba52, uba80, ubb, ubc, ubcep1, ubcep2, ubq.
|
|
|
Chains:
A, C, E, G
(303 residues)
CATH domain:
|
|
|
|
|
|
The crystal structure of porcine reproductive and respiratory syndrome virus (prrsv) leader protease nsp1
|
|
|
Source: Porcine reproductive and respiratory syndrome virus. Prrsv. Organism_taxid: 28344. Gene: orf1a. Expressed in: escherichia coli bl21(de3). Expression_system_taxid: 469008.
|
|
|
Chain:
A
(175 residues)
CATH domains:
|
|
|
|
|
|
Crystal structure of the s18y variant of ubiquitin carboxy terminal hydrolase l1 bound to ubiquitin vinylmethylester.
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: pgp9.5, uchl1. Expressed in: escherichia coli. Expression_system_taxid: 562. Gene: rps27a, uba52, uba80, ubb, ubc, ubcep1, ubcep2, ubiq_human.
|
|
|
Chain:
A
(223 residues)
CATH domain:
|
|
|
|
|
|
Covalent ubiquitin-usp5 complex
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: isot, usp5. Expressed in: escherichia coli. Expression_system_taxid: 562. Gene: rps27a, uba52, uba80, ubb, ubc, ubcep1, ubcep2.
|
|
|
Chains:
A, B
(673 residues)
CATH domains:
|
|
|
|
|
|
Crystal structure of uch37
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: ad-019, cgi-70, uch37, uchl5. Expressed in: escherichia coli. Expression_system_taxid: 562.
|
|
|
Chain:
A
(282 residues)
CATH domains:
|
|
|
|
|
|
Crystal structure of the i93m mutant of ubiquitin carboxy-terminal hydrolase l1
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: pgp9.5, uchl1. Expressed in: escherichia coli. Expression_system_taxid: 562.
|
|
|
Chains:
A, B
(223 residues)
CATH domain:
|
|
|
|
|
|
The octameric sars-cov main protease
|
|
|
Source: Sars coronavirus. Sars-cov. Organism_taxid: 227859. Expressed in: escherichia coli. Expression_system_taxid: 562. Synthetic: yes. Synthetic construct. Organism_taxid: 32630
|
|
|
Chains:
A, B, C, D
(301 residues)
CATH domains:
|
|
|
|
|
|
Formation of an intricate helical bundle dictates the assembly of the 26s proteasome lid
|
|
|
Source: Saccharomyces cerevisiae. Baker's yeast. Organism_taxid: 559292. Strain: atcc 204508 / s288c. Strain: atcc 204508 / s288c
|
|
|
Chain:
V
(63 residues)
|
|
|
|
|
|
Model of the human eif3 pci-mpn octamer docked into the 43s-hcv ires em map
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Organism_taxid: 9606
|
|
|
Chain:
F
(232 residues)
|
|
|
|
|
|
Model of the human eif3 pci-mpn octamer docked into the 43s em map
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Organism_taxid: 9606
|
|
|
Chain:
F
(232 residues)
|
|
|
|
|
|
Structure of the yeast 26s proteasome lid sub-complex
|
|
|
Source: Saccharomyces cerevisiae s288c. Baker's yeast. Organism_taxid: 559292. Strain: atcc 204508 / s288c. Cellular_location: cytoplasm. Gene: rpn3, sun2, yer021w. Expressed in: escherichia coli bl21(de3). Expression_system_taxid: 469008. Gene: rpn5, nas5, ydl147w, d1572.
|
|
|
Chain:
G
(257 residues)
|
|
|
|
|
|
3d structure determination of the human U4/u6.U5 Tri-snrnp complex
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Organism_taxid: 9606
|
|
|
Chain:
V
(431 residues)
|
|
|
|
|
|
Crystal structure of the n-terminal domains of the ubiquitin specific peptidase 4 (usp4)
|
|
|
Source: Mus musculus. Mouse. Organism_taxid: 10090. Gene: usp4. Expressed in: escherichia coli. Expression_system_taxid: 562
|
|
|
Chains:
A, B
(220 residues)
CATH domains:
|
|
|
|
|
|
Structure of a cubic crystal form of x (adrp) domain from fcov with adp-ribose
|
|
|
Source: Feline coronavirus. Fcov. Organism_taxid: 33734. Strain: fipv wsu-79/1146. Gene: rep, 1a-1b. Expressed in: escherichia coli. Expression_system_taxid: 469008.
|
|
|
Chains:
A, B, C, D, E, F, G, H
(168 residues)
CATH domain:
|
|
|
|
|
|
Crystal structure of the i93m mutant of ubiquitin carboxy terminal hydrolase l1 bound to ubiquitin vinylmethylester
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: pgp9.5, uchl1. Expressed in: escherichia coli. Expression_system_taxid: 562. Gene: rps27a, uba52, uba80, ubb, ubc, ubcep1, ubcep2, ubiq_human.
|
|
|
Chain:
A
(223 residues)
CATH domain:
|
|
|
|
|
|
Crystal structure of ubiquitin carboxy terminal hydrolase l1 bound to ubiquitin vinylmethylester
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: pgp9.5, uchl1. Expressed in: escherichia coli. Expression_system_taxid: 562. Gene: rps27a, uba52, uba80, ubb, ubc, ubcep1, ubcep2, ubiq_human.
|
|
|
Chain:
A
(223 residues)
CATH domain:
|
|
|
|
|
|
Crystal structure of ibv nsp2a
|
|
|
Source: Avian infectious bronchitis virus (strain m41). Ibv. Organism_taxid: 11127. Strain: m41. Gene: 1a, 1ab. Expressed in: escherichia coli. Expression_system_taxid: 562.
|
|
|
Chain:
A
(359 residues)
|
|
|
|
|
|
Oligomeric structure of the dusp domain of human usp15
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: kiaa0529, usp15. Expressed in: escherichia coli. Expression_system_taxid: 469008.
|
|
|
Chains:
A, B
(132 residues)
CATH domain:
|
|
|
|
|
|
Crystal structure of sars-cov main protease asn214ala mutant with authorize n-terminus
|
|
|
Source: Sars coronavirus. Sars-cov. Organism_taxid: 227859. Gene: main protease. Expressed in: escherichia coli. Expression_system_taxid: 562.
|
|
|
Chains:
A, B
(306 residues)
CATH domains:
|
|
|
|
|
|
Sars-cov main protease monomeric arg298ala mutant with n-terminal additional residues (gly-ser)
|
|
|
Source: Sars coronavirus. Sars-cov. Organism_taxid: 227859. Expressed in: escherichia coli. Expression_system_taxid: 562.
|
|
|
Chain:
A
(307 residues)
CATH domains:
|
|
|
|
|
|
Sars-cov main protease triple mutant sti/a with two n-terminal additional residue (gly-ser)
|
|
|
Source: Sars coronavirus. Sars-cov. Organism_taxid: 227859. Expressed in: escherichia coli. Expression_system_taxid: 562.
|
|
|
Chains:
A, B
(306 residues)
CATH domains:
|
|
|
|
|
|
Structure of the ubp8-sgf11-sgf73-sus1 saga dub module
|
|
|
Source: Saccharomyces cerevisiae. Brewer's yeast,lager beer yeast,yeast. Organism_taxid: 4932. Gene: ubp8, ym9959.05, ymr223w. Expressed in: escherichia coli. Expression_system_taxid: 562. Yeast. Gene: sgf11, ypl047w. Gene: sus1, ybr111w-a.
|
|
|
Chain:
A
(422 residues)
CATH domains:
|
|
|
|
|
|
Structure of the saga ubp8/sgf11/sus1/sgf73 dub module
|
|
|
Source: Saccharomyces cerevisiae. Brewer's yeast,lager beer yeast,yeast. Organism_taxid: 4932. Gene: ubp8, ymr223w, ym9959.05. Expressed in: escherichia coli. Expression_system_taxid: 562. Gene: sus1, ybr111w-a. Gene: sgf11, ypl047w. Gene: sgf73, ygl066w.
|
|
|
Chain:
A
(433 residues)
CATH domains:
|
|
|
|
|
|
Structure of the saga ubp8/sgf11/sus1/sgf73 dub module bound to ubiquitin aldehyde
|
|
|
Source: Saccharomyces cerevisiae. Brewer's yeast,lager beer yeast,yeast. Organism_taxid: 4932. Gene: ubp8, ymr223w, ym9959.05. Expressed in: escherichia coli. Expression_system_taxid: 562. Gene: sus1, ybr111w-a. Gene: sgf11, ypl047w. Homo sapiens.
|
|
|
Chain:
A
(455 residues)
CATH domains:
|
|
|
|
|
|
Severe acute respiratory syndrome-coronavirus papain-like protease inhibitors: design, synthesis, protein-ligand x-ray structure and biological evaluation
|
|
|
Source: Sars coronavirus. Sars-cov. Organism_taxid: 227859. Strain: urbani. Gene: 1a, orf1 (nsp3) residues 1544-1855. Expressed in: escherichia coli. Expression_system_taxid: 562.
|
|
|
Chains:
A, B
(312 residues)
CATH domains:
|
|
|
|
|
|
Crystal structure of transmissible gastroenteritis virus papain-like protease 1
|
|
|
Source: Porcine transmissible gastroenteritis coronavirus. Tgev. Organism_taxid: 11151. Strain: purdue. Gene: 1a. Expressed in: escherichia coli. Expression_system_taxid: 562.
|
|
|
Chain:
A
(211 residues)
|
|
|
|
|
|
Crystal structure of the usp7:hdmx(ahss) complex
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Strain: human. Gene: hausp, usp7. Expressed in: escherichia coli. Expression_system_taxid: 469008. Synthetic: yes. Organism_taxid: 9606
|
|
|
Chain:
A
(137 residues)
CATH domain:
|
|
|
|
|
|
Crystal structure of the usp7:hdm2(psts) complex
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: hausp, usp7. Expressed in: escherichia coli. Expression_system_taxid: 469008. Synthetic: yes. Organism_taxid: 9606
|
|
|
Chain:
C
(137 residues)
CATH domain:
|
|
|
|
|
|
Usp21 in complex with a ubiquitin-based, usp21-specific inhibitor
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: pp1490, usp21, usp23. Expressed in: escherichia coli. Expression_system_taxid: 511693. Gene: rps27a, uba52, uba80, ubb, ubc, ubcep1, ubcep2, ubq.
|
|
|
Chains:
A, C
(316 residues)
CATH domain:
|
|
|
|
|
|
The crystal structure of the prrsv nonstructural protein nsp1
|
|
|
Source: Porcine reproductive and respiratory syndrome virus. Prrsv. Organism_taxid: 28344. Expressed in: escherichia coli. Expression_system_taxid: 469008.
|
|
|
Chain:
A
(203 residues)
CATH domains:
|
|
|
|
|
|
The catalytic domain of usp8 in complex with a usp8 specific inhibitor
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: kiaa0055, ubpy, usp8. Expressed in: escherichia coli. Expression_system_taxid: 562. Gene: rps27a, uba52, uba80, ubb, ubc, ubcep1, ubcep2, ubq.
|
|
|
Chain:
A
(355 residues)
CATH domain:
|
|
|
|
|
|
High resolution structure (1.26a) of usp2a in complex with ubiquitin
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: ubp41, usp2. Expressed in: escherichia coli. Expression_system_taxid: 469008. Gene: rps27a, uba52, ubb, ubc.
|
|
|
Chain:
A
(338 residues)
CATH domain:
|
|
|
|
|
|
Crystal structure of a josephin-ubiquitin complex: evolutionary restraints on ataxin-3 deubiquitinating activity
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: atx3l, atxn3l, mjdl. Expressed in: escherichia coli. Expression_system_taxid: 562. Gene: ubb.
|
|
|
Chains:
A, C, E, G
(181 residues)
CATH domains:
|
|
|
|
|
|
Crystal structure of the a20 znf4 and ubiquitin complex
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: ubb. Expressed in: escherichia coli. Expression_system_taxid: 469008. Gene: tnfaip3, otud7c.
|
|
|
Chains:
I, J, K, L, M, N, O, P
(33 residues)
|
|
|
|
|
|
Crystal structure of the a20 znf4, ubiquitin and ubch5a complex
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: ube2d1, sft, ubc5a, ubch5, ubch5a. Expressed in: escherichia coli. Expression_system_taxid: 469008. Gene: ubb. Gene: tnfaip3, otud7c.
|
|
|
Chains:
C, F
(31 residues)
|
|
|
|
|
|
The catalytic domain of human otud5
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: otud5. Expressed in: escherichia coli. Expression_system_taxid: 469008.
|
|
|
Chain:
A
(129 residues)
CATH domains:
|
|
|
|
|
|
Otu domain of crimean congo hemorrhagic fever virus
|
|
|
Source: Crimean-congo hemorrhagic fever virus strain ibar10200. Cchfv. Organism_taxid: 652961. Strain: nigeria/ibar10200/1970. Gene: l. Expressed in: escherichia coli. Expression_system_taxid: 562
|
|
|
Chains:
A, B
(184 residues)
CATH domains:
|
|
|
|
|
|
Otu domain of crimean congo hemorrhagic fever virus in complex with ubiquitin
|
|
|
Source: Crimean-congo hemorrhagic fever virus strain ibar10200. Cchfv. Organism_taxid: 652961. Strain: nigeria/ibar10200/1970. Gene: l. Expressed in: escherichia coli. Expression_system_taxid: 562. Homo sapiens.
|
|
|
Chains:
A, C, E, G
(156 residues)
CATH domain:
|
|
|
|
|
|
Otu domain of crimean congo hemorrhagic fever virus in complex with isg15
|
|
|
Source: Crimean-congo hemorrhagic fever virus. Cchfv. Organism_taxid: 652961. Strain: nigeria/ibar10200/1970. Gene: l. Expressed in: escherichia coli. Expression_system_taxid: 562. Homo sapiens. Human.
|
|
|
Chain:
A
(162 residues)
CATH domain:
|
|
|
|
|
|
Structure of the dusp-ubl domains of usp15
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: kiaa0529, usp15. Expressed in: escherichia coli. Expression_system_taxid: 469008.
|
|
|
Chain:
A
(209 residues)
CATH domains:
|
|
|
|
|
|
Structural analysis of a viral otu domain protease from the crimean- congo hemorrhagic fever virus in complex with human ubiquitin
|
|
|
Source: Crimean-congo hemorrhagic fever virus. Organism_taxid: 11593. Strain: ibar10200. Expressed in: escherichia coli. Expression_system_taxid: 469008. Homo sapiens. Human. Organism_taxid: 9606. Gene: ubb.
|
|
|
Chains:
A, C
(161 residues)
CATH domain:
|
|
|
|
|
|
Structural analysis of a viral otu domain protease from the crimean- congo hemorrhagic fever virus in complex with human ubiquitin
|
|
|
Source: Crimean-congo hemorrhagic fever virus. Organism_taxid: 11593. Strain: ibar10200. Expressed in: escherichia coli. Expression_system_taxid: 469008. Homo sapiens. Human. Organism_taxid: 9606. Gene: ubb.
|
|
|
Chains:
A, C
(161 residues)
CATH domain:
|
|
|
|
|
|
Structure of a viral otu domain protease bound to interferon- stimulated gene 15 (isg15)
|
|
|
Source: Crimean-congo hemorrhagic fever virus. Organism_taxid: 11593. Expressed in: escherichia coli. Expression_system_taxid: 562. Homo sapiens. Human. Organism_taxid: 9606. Gene: isg15, g1p2, ucrp. Expression_system_taxid: 562
|
|
|
Chain:
A
(164 residues)
CATH domain:
|
|
|
|
|
|
Structure of a viral otu domain protease bound to ubiquitin
|
|
|
Source: Crimean-congo hemorrhagic fever virus. Organism_taxid: 11593. Expressed in: escherichia coli. Expression_system_taxid: 469008. Other_details: n-terminal glutathione-s-transferase fusion. Homo sapiens. Human. Organism_taxid: 9606. Gene: ubb.
|
|
|
Chain:
A
(164 residues)
CATH domain:
|
|
|
|
|
|
Crystal structure of the usp15 dusp-ubl domains
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: usp15, kiaa0529. Expressed in: escherichia coli. Expression_system_taxid: 562.
|
|
|
Chains:
A, B
(215 residues)
CATH domains:
|
|
|
|
|
|
Crystal structure of nsp10/nsp16 complex of sars coronavirus
|
|
|
Source: Sars coronavirus. Sars-cov. Organism_taxid: 227859. Gene: rep, 1a-1b. Expressed in: escherichia coli. Expression_system_taxid: 469008. Gene: 1a.
|
|
|
Chains:
A, B
(292 residues)
CATH domain:
|
|
|
|
|
|
Crystal structure of the catalytic domain of uchl5, a proteasome- associated human deubiquitinating enzyme, reveals an unproductive form of the enzyme
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: ad-019, cgi-70, uch37, uchl5. Expressed in: escherichia coli. Expression_system_taxid: 469008.
|
|
|
Chains:
A, B
(212 residues)
CATH domain:
|
|
|
|
|
|
Crystal structure of the catalytic domain of uchl5, a proteasome- associated human deubiquitinating enzyme, reveals an unproductive form of the enzyme
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: ad-019, cgi-70, uch37, uchl5. Expressed in: escherichia coli. Expression_system_taxid: 469008.
|
|
|
Chains:
A, B, C, D
(227 residues)
CATH domain:
|
|
|
|
|
|
Crystal structure of sars coronavirus main protease complexed with cm- ff-h (soaking)
|
|
|
Source: Sars coronavirus. Sars-cov. Organism_taxid: 227859. Expressed in: escherichia coli. Expression_system_taxid: 562
|
|
|
Chain:
A
(306 residues)
CATH domains:
|
|
|
|
|
|
Crystal structure of sars coronavirus main protease complexed with ac- nsfsq-h (soaking)
|
|
|
Source: Sars coronavirus. Sars-cov. Organism_taxid: 227859. Expressed in: escherichia coli. Expression_system_taxid: 562. Synthetic: yes
|
|
|
Chain:
A
(301 residues)
CATH domains:
|
|
|
|
|
|
Crystal structure of sars coronavirus main protease complexed with ac- dsfdq-h (soaking)
|
|
|
Source: Sars coronavirus. Sars-cov. Organism_taxid: 227859. Expressed in: escherichia coli. Expression_system_taxid: 562. Synthetic: yes
|
|
|
Chain:
A
(306 residues)
CATH domains:
|
|
|
|
|
|
Crystal structure of sars coronavirus main protease complexed with ac- nstsq-h (soaking)
|
|
|
Source: Sars coronavirus. Sars-cov. Organism_taxid: 227859. Expressed in: escherichia coli. Expression_system_taxid: 562. Synthetic: yes
|
|
|
Chain:
A
(306 residues)
CATH domains:
|
|
|
|
|
|
Crystal structure of sars coronavirus main protease complexed with ac- estlq-h (cocrystallization)
|
|
|
Source: Sars coronavirus. Sars-cov. Organism_taxid: 227859. Expressed in: escherichia coli. Expression_system_taxid: 562. Synthetic: yes
|
|
|
Chains:
A, B
(306 residues)
CATH domains:
|
|
|
|
|
|
Crystal structure of sars coronavirus main protease complexed with ac- estlq-h (soaking)
|
|
|
Source: Sars coronavirus. Sars-cov. Organism_taxid: 227859. Expressed in: escherichia coli. Expression_system_taxid: 562. Synthetic: yes
|
|
|
Chain:
A
(306 residues)
CATH domains:
|
|
|
|
|
|
Crystal structure of sars coronavirus main protease complexed with an alpha, beta-unsaturated ethyl ester sg75
|
|
|
Source: Sars coronavirus. Sars-cov. Organism_taxid: 227859. Expressed in: escherichia coli. Expression_system_taxid: 562
|
|
|
Chain:
A
(306 residues)
CATH domains:
|
|
|
|
|
|
Structure of n-terminal dusp-ubl domains of human usp15
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: kiaa0529, usp15, usp15 (1-222). Expressed in: escherichia coli. Expression_system_taxid: 469008.
|
|
|
Chain:
A
(222 residues)
CATH domains:
|
|
|
|
|
|
Crystal structure of the uch domain of uch-l5 with 6 residues deleted
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: ad-019, cgi-70, uch-l5, uch37, uchl5. Expressed in: escherichia coli. Expression_system_taxid: 562
|
|
|
Chains:
A, B
(204 residues)
CATH domain:
|
|
|
|
|
|
Crystal structure of sars coronavirus main protease complexed with an alpha, beta-unsaturated ethyl ester sg81
|
|
|
Source: Sars coronavirus. Sars-cov. Organism_taxid: 227859. Expressed in: escherichia coli. Expression_system_taxid: 562
|
|
|
Chain:
A
(306 residues)
CATH domains:
|
|
|
|
|
|
Crystal structure of sars coronavirus main protease complexed with an alpha,beta-unsaturated ethyl ester inhibitor sg82
|
|
|
Source: Sars coronavirus. Sars-cov. Organism_taxid: 227859. Expressed in: escherichia coli. Expression_system_taxid: 562
|
|
|
Chain:
A
(306 residues)
CATH domains:
|
|
|
|
|
|
Crystal structure of hcov-nl63 3c-like protease
|
|
|
Source: Human coronavirus. Hcov-nl63. Organism_taxid: 277944. Strain: nl63. Gene: 1a. Expressed in: escherichia coli. Expression_system_taxid: 562
|
|
|
Chains:
A, B
(302 residues)
CATH domains:
|
|
|
|
|
|
The catalytic domain of human deubiquitinase duba
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: duba, otud5. Expressed in: escherichia coli. Expression_system_taxid: 469008.
|
|
|
Chain:
A
(141 residues)
CATH domains:
|
|
|
|
|
|
The catalytic domain of human deubiquitinase duba in complex with ubiquitin aldehyde
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: duba, otud5. Expressed in: escherichia coli. Expression_system_taxid: 469008. Gene: ubc, ubiquitin aldehyde. Expression_system_taxid: 562
|
|
|
Chains:
A, C, E, G
(166 residues)
CATH domain:
|
|
|
|
|
|
Crystal structure of sars coronavirus main protease complexed with an alpha, beta-unsaturated ethyl ester inhibitor sg83
|
|
|
Source: Sars coronavirus. Sars-cov. Organism_taxid: 227859. Expressed in: escherichia coli. Expression_system_taxid: 562
|
|
|
Chain:
A
(306 residues)
CATH domains:
|
|
|
|
|
|
Crystal structure of sars coronavirus main protease complexed with an alpha, beta-unsaturated ethyl ester inhibitor sg85
|
|
|
Source: Sars coronavirus. Sars-cov. Organism_taxid: 227859. Expressed in: escherichia coli. Expression_system_taxid: 562
|
|
|
Chain:
A
(306 residues)
CATH domains:
|
|
|
|
|
|
The pleckstrin homology (ph) domain of usp37
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: usp37. Expressed in: escherichia coli. Expression_system_taxid: 469008.
|
|
|
Chains:
A, B
(104 residues)
CATH domain:
|
|
|
|
|
|
Crystal structure of the nonstructural protein 7 and 8 complex of feline coronavirus
|
|
|
Source: Feline infectious peritonitis virus. Fcov. Organism_taxid: 33734. Strain: fipv wsu-79/1146. Gene: rep, 1a-1b. Expressed in: escherichia coli. Expression_system_taxid: 562. Expression_system_taxid: 562
|
|
|
Chains:
A, B, C, D, E, F
(190 residues)
CATH domains:
Unassigned
Unassigned
|
|
|
|
|
|
Severe acute respiratory syndrome coronavirus (sars-cov) 3cl protease in complex with n-[(1r)-2-(tert-butylamino)-2-oxo-1-(pyridin-3-yl) ethyl]-n-(4-tert-butylphenyl)furan-2-carboxamide inhibitor.
|
|
|
Source: Sars coronavirus. Sars-cov. Organism_taxid: 227859. Gene: 1a. Expressed in: homo sapiens. Expression_system_taxid: 9606
|
|
|
Chain:
A
(306 residues)
CATH domains:
|
|
|
|
|
|
Crystal structure of usp2 in complex with mutated ubiquitin
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: ubp41, usp02.258.605, usp2. Expressed in: escherichia coli. Expression_system_taxid: 469008. Gene: ubc.
|
|
|
Chain:
A
(327 residues)
CATH domain:
|
|
|
|
|
|
Crystal structure of usp2 and a mutant form of ubiquitin
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: ubp41, usp02.258.605, usp2. Expressed in: escherichia coli. Expression_system_taxid: 469008. Gene: ubc.
|
|
|
Chain:
A
(328 residues)
CATH domain:
|
|
|
|
|
|
Crystal structure of sars-cov 3c-like protease in apo form
|
|
|
Source: Sars coronavirus. Sars-cov. Organism_taxid: 227859. Gene: 1a. Expressed in: escherichia coli. Expression_system_taxid: 562.
|
|
|
Chains:
A, B
(301 residues)
CATH domains:
|
|
|
|
|
|
Crystal structure of sars-cov 3c-like protease with b4z
|
|
|
Source: Sars coronavirus. Sars-cov. Organism_taxid: 227859. Gene: 1a. Expressed in: escherichia coli. Expression_system_taxid: 562. Synthetic: yes. Other_details: synthetic inhibitor
|
|
|
Chains:
A, B
(301 residues)
CATH domains:
|
|
|
|
|
|
Crystal structure of sars-cov 3c-like protease with c4z
|
|
|
Source: Sars coronavirus. Sars-cov. Organism_taxid: 227859. Gene: 1a. Expressed in: escherichia coli. Expression_system_taxid: 562. Synthetic: yes. Other_details: synthetic inhibitor
|
|
|
Chains:
A, B
(301 residues)
CATH domains:
|
|
|
|
|
|
Crystal structure of sars-cov 3c-like protease with c6z
|
|
|
Source: Sars coronavirus. Sars-cov. Organism_taxid: 227859. Gene: 1a. Expressed in: escherichia coli. Expression_system_taxid: 562. Synthetic: yes. Other_details: synthetic inhibitor
|
|
|
Chains:
A, B
(301 residues)
CATH domains:
|
|
|
|
|
|
Crystal structure of sars-cov 3c-like protease with m4z
|
|
|
Source: Sars coronavirus. Sars-cov. Organism_taxid: 227859. Gene: 1a. Expressed in: escherichia coli. Expression_system_taxid: 562. Synthetic: yes. Other_details: synthetic inhibitor
|
|
|
Chains:
A, B
(301 residues)
CATH domains:
|
|
|
|
|
|
Crystal structure of thE C-terminal cytoplasmic domain of non- structural protein 4 from mouse hepatitis virus a59
|
|
|
Source: Murine hepatitis virus. Organism_taxid: 591071. Strain: a59. Gene: murine hepatitis virus strain a59 orf1ab, orf1a. Expressed in: escherichia coli. Expression_system_taxid: 469008.
|
|
|
Chains:
A, B
(81 residues)
CATH domain:
|
|
|
|
|
|
C425s mutant of thE C-terminal cytoplasmic domain of non-structural protein 4 from mouse hepatitis virus a59
|
|
|
Source: Murine hepatitis virus. Organism_taxid: 591071. Strain: a59. Gene: murine hepatitis virus strain a59 orf1ab, orf1a. Expressed in: escherichia coli. Expression_system_taxid: 469008.
|
|
|
Chains:
A, B
(89 residues)
CATH domain:
|
|
|
|
|
|
Crystalstructure of the ubiquitin protease
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: hspc263, otb1, otu1, otub1. Expressed in: escherichia coli. Expression_system_taxid: 562. Gene: mms2, ube2v2, uev2. Gene: blu, ubc13, ube2n.
|
|
|
Chains:
A, H, O, V, c, j
(210 residues)
CATH domains:
|
|
|
|
|
|
Crystal structure of a20 zf7 in complex with linear ubiquitin, form i
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: ubc. Expressed in: escherichia coli. Expression_system_taxid: 562. Gene: tnfaip3.
|
|
|
Chains:
E, F, G
(31 residues)
|
|
|
|
|
|
Crystal structure of a20 zf7 in complex with linear ubiquitin, form ii
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: ubc. Expressed in: escherichia coli. Expression_system_taxid: 562. Gene: tnfaip3.
|
|
|
Chains:
E, F, G
(33 residues)
|
|
|
|
|
|
Crystal structure of a20 zf7 in complex with linear tetraubiquitin
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: ubc. Expressed in: escherichia coli. Expression_system_taxid: 562. Gene: tnfaip3.
|
|
|
Chains:
D, F, E
(33 residues)
|
|
|
|
|
|
Crystal structure of cyld usp domain (c596s) in complex with met1- linked diubiquitin
|
|
|
Source: Danio rerio. Zebra fish. Organism_taxid: 7955. Gene: cyld, cylda. Expressed in: escherichia coli. Expression_system_taxid: 562. Homo sapiens. Human. Organism_taxid: 9606.
|
|
|
Chain:
A
(301 residues)
CATH domain:
|
|
|
|
|
|
Crystal structure of cyld usp domain (c596s e674q) in complex with met1-linked diubiquitin
|
|
|
Source: Danio rerio. Zebra fish. Organism_taxid: 7955. Gene: cyld, cylda. Expressed in: escherichia coli. Expression_system_taxid: 562. Homo sapiens. Human. Organism_taxid: 9606.
|
|
|
Chains:
A, C
(299 residues)
CATH domain:
|
|
|
|
|
|
Crystal structure of cyld usp domain (c596a) in complex with lys63- linked diubiquitin
|
|
|
Source: Danio rerio. Zebra fish. Organism_taxid: 7955. Gene: cyld, cylda. Expressed in: escherichia coli. Expression_system_taxid: 562. Mus musculus. Mouse. Organism_taxid: 10090.
|
|
|
Chains:
A, D
(300 residues)
CATH domain:
|
|
|
|
|
|
Structure of tgev nsp1
|
|
|
Source: Porcine transmissible gastroenteritis coronavirus. Organism_taxid: 11151. Strain: purdue. Expressed in: escherichia coli. Expression_system_taxid: 511693.
|
|
|
Chains:
A, B
(110 residues)
CATH domain:
|
|
|
|
|
|
A20 otu domain in reduced, active state at 1.87 a resolution
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Expressed in: escherichia coli. Expression_system_taxid: 511693.
|
|
|
Chains:
A, B
(325 residues)
|
|
|
|
|
|
A20 otu domain in reversibly oxidised (soh) state
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Expressed in: escherichia coli. Expression_system_taxid: 511693.
|
|
|
Chains:
A, B
(329 residues)
|
|
|
|
|
|
A20 otu domain with irreversibly oxidised cys103 from 270 min h2o2 soak.
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Expressed in: escherichia coli. Expression_system_taxid: 511693.
|
|
|
Chains:
A, B
(323 residues)
|
|
|
|
|
|
A20 otu domain with irreversibly oxidised cys103 from 60 min h2o2 soak.
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Expressed in: escherichia coli. Expression_system_taxid: 511693.
|
|
|
Chains:
A, B
(327 residues)
|
|
|
|
|
|
Crimean congo hemorrhagic fever virus otu domain in complex with ubiquitin-propargyl.
|
|
|
Source: Crimean-congo hemorrhagic fever virus. Organism_taxid: 652961. Strain: ibar10200. Expressed in: escherichia coli. Expression_system_taxid: 511693. Expression_system_variant: rosetta2 placi. Other_details: DNA generated by gene synthesis. Synthetic: yes. Homo sapiens.
|
|
|
Chain:
A
(153 residues)
CATH domain:
|
|
|
|
|
|
Crystal structure of the otu domain of otulin at 1.3 angstroms.
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Expressed in: escherichia coli. Expression_system_taxid: 511693. Expression_system_variant: rosetta placi.
|
|
|
Chain:
A
(269 residues)
|
|
|
|
|
|
Crystal structure of the otu domain of otulin d336a mutant
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Expressed in: escherichia coli. Expression_system_taxid: 511693. Expression_system_variant: rosetta placi.
|
|
|
Chain:
A
(260 residues)
|
|
|
|
|
|
Crystal structure of otulin otu domain (c129a) in complex with met1- di ubiquitin
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Expressed in: escherichia coli. Expression_system_taxid: 511693. Expression_system_variant: rosetta placi.
|
|
|
Chain:
A
(266 residues)
|
|
|
|
|
|
Crystal structure of the lys29, lys33-linkage-specific trabid otu deubiquitinase domain reveals an ankyrin-repeat ubiquitin binding domain (ankubd)
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Expressed in: escherichia coli. Expression_system_taxid: 511693. Other_details: arcticexpress competent cells
|
|
|
Chain:
A
(428 residues)
CATH domain:
|
|
|
|
|
|
Crystal structure of the usp15 dusp-ubl monomer
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Expressed in: escherichia coli. Expression_system_taxid: 511693.
|
|
|
Chains:
A, B
(211 residues)
CATH domains:
|
|
|
|
|
|
Structure of usp15 dusp-ubl deletion mutant
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Expressed in: escherichia coli. Expression_system_taxid: 511693.
|
|
|
Chain:
A
(210 residues)
CATH domains:
|
|
|
|
|
|
Turnip yellow mosaic virus proteinase and escherichia coli 30s ribosomal s15
|
|
|
Source: Turnip yellow mosaic virus. Organism_taxid: 12154. Expressed in: escherichia coli. Expression_system_taxid: 469008. Escherichia coli. Organism_taxid: 469008. Strain: bl21(de3)
|
|
|
Chain:
A
(148 residues)
CATH domain:
|
|
|
|
|
|
Structure of otud1 otu domain
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Expressed in: escherichia coli. Expression_system_taxid: 469008. Expression_system_variant: rosetta placi
|
|
|
Chains:
A, B
(149 residues)
CATH domain:
|
|
|
|
|
|
Structure of otud2 otu domain
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Expressed in: escherichia coli. Expression_system_taxid: 469008. Expression_system_variant: rosetta placi
|
|
|
Chain:
A
(175 residues)
CATH domain:
|
|
|
|
|
|
Structure of otud2 otu domain in complex with ubiquitin k11-linked peptide
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Expressed in: escherichia coli. Expression_system_taxid: 469008. Expression_system_variant: rosetta placi.
|
|
|
Chains:
A, B
(164 residues)
CATH domain:
|
|
|
|
|
|
Structure of otud3 otu domain
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Expressed in: escherichia coli. Expression_system_taxid: 469008. Expression_system_variant: rosetta placi.
|
|
|
Chain:
A
(141 residues)
CATH domain:
|
|
|
|
|
|
Structure of otud2 otu domain in complex with k11-linked di ubiquitin
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Expressed in: escherichia coli. Expression_system_taxid: 469008. Expression_system_variant: rosetta placi.
|
|
|
Chains:
A, D
(158 residues)
CATH domain:
|
|
|
|
|
|
Deep classification of a large cryo-em dataset defines the conformational landscape of the 26s proteasome
|
|
|
Source: Saccharomyces cerevisiae. Baker's yeast. Organism_taxid: 4932. Organism_taxid: 4932
|
|
|
Chain:
V
(247 residues)
|
|
|
|
|
|
Deep classification of a large cryo-em dataset defines the conformational landscape of the 26s proteasome
|
|
|
Source: Saccharomyces cerevisiae. Baker's yeast. Organism_taxid: 4932. Organism_taxid: 4932
|
|
|
Chain:
V
(247 residues)
|
|
|
|
|
|
Deep classification of a large cryo-em dataset defines the conformational landscape of the 26s proteasome
|
|
|
Source: Saccharomyces cerevisiae. Baker's yeast. Organism_taxid: 4932. Organism_taxid: 4932
|
|
|
Chain:
V
(247 residues)
|
|
|
|
|
|
Crystal structure of human otub1/ubch5b~ub/ub
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: e2, hspc263, otb1, otu1, otub1, ubc4, ubc5b, ubch4, ubch5b, ube2d2. Expressed in: escherichia coli. Expression_system_taxid: 562. Gene: ubc. Expression_system_taxid: 562
|
|
|
Chains:
A, B, C, J, K, L
(399 residues)
CATH domains:
|
|
|
|
|
|
Crystal structure of human otub1/ubch5b~ub/ub
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: ube2d2, ubc4, ubc5b, ubch4, ubch5b, hspc263, otb1, otu1, otub1. Expressed in: escherichia coli. Expression_system_taxid: 562. Gene: ubc. Expression_system_taxid: 562
|
|
|
Chains:
A, B, C
(399 residues)
CATH domains:
|
|
|
|
|
|
Structure of c. Elegans otub1 bound to human ubc13
|
|
|
Source: Caenorhabditis elegans. Nematode. Organism_taxid: 6239. Gene: otub-1, c25d7.8. Expressed in: escherichia coli. Expression_system_taxid: 562. Homo sapiens. Human. Organism_taxid: 9606.
|
|
|
Chain:
B
(238 residues)
CATH domains:
|
|
|
|
|
|
The structure of a ceotub1 ubiquitin aldehyde ubc13~ub complex
|
|
|
Source: Caenorhabditis elegans. Nematode. Organism_taxid: 6239. Gene: otub-1, c25d7.8. Expressed in: escherichia coli. Expression_system_taxid: 562. Homo sapiens. Human. Organism_taxid: 9606.
|
|
|
Chains:
A, E, I, L
(248 residues)
CATH domains:
|
|
|
|
|
|
The structure of h/ceotub1-ubiquitin aldehyde-ubc13~ub
|
|
|
Source: Homo sapiens, caenorhabditis elegans. Human, nematode. Organism_taxid: 9606, 6239. Gene: otub1, otb1, otu1, hspc263, c25d7.8, otub-1. Expressed in: escherichia coli. Expression_system_taxid: 562. Homo sapiens. Human. Organism_taxid: 9606.
|
|
|
Chain:
A
(256 residues)
CATH domains:
|
|
|
|
|
|
The crystal structure of ubiquitin carboxy-terminal hydrolase l1 (uchl1) bound to a tripeptide fluoromethyl ketone z-vae(ome)-fmk
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: uchl1. Expressed in: escherichia coli. Expression_system_taxid: 562. Synthetic: yes
|
|
|
Chains:
A, B
(223 residues)
CATH domain:
|
|
|
|
|
|
2.25a resolution structure of transmissible gastroenteritis virus protease containing a covalently bound dipeptidyl inhibitor
|
|
|
Source: Porcine transmissible gastroenteritis coronavirus. Tgev. Organism_taxid: 11151. Strain: purdue. Gene: 1a. Expressed in: escherichia coli. Expression_system_taxid: 511693.
|
|
|
Chains:
A, B, C, D
(300 residues)
CATH domains:
|
|
|
|
|
|
Structure of the saga ubp8(s144n)/sgf11(1-72, delta-znf)/sus1/sgf73 dub module
|
|
|
Source: Saccharomyces cerevisiae. Baker's yeast. Organism_taxid: 559292. Strain: atcc 204508 / s288c. Gene: ubp8, ym9959.05, ymr223w. Expressed in: escherichia coli. Expression_system_taxid: 469008. Gene: sus1, ybr111w-a. Gene: sgf11, ypl047w.
|
|
|
Chains:
A, E
(450 residues)
CATH domains:
|
|
|
|
|
|
Structure of the saga ubp8/sgf11(1-72, delta-znf)/sus1/sgf73 dub module
|
|
|
Source: Saccharomyces cerevisiae. Baker's yeast. Organism_taxid: 559292. Strain: atcc 204508 / s288c. Gene: ubp8, ym9959.05, ymr223w. Expressed in: escherichia coli. Expression_system_taxid: 469008. Gene: sus1, ybr111w-a. Gene: sgf11, ypl047w.
|
|
|
Chains:
A, E
(447 residues)
CATH domains:
|
|
|
|
|
|
Crystal structure of human otubain2 and ubiquitin complex
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: otub2, c14orf137, otb2, otu2. Expressed in: escherichia coli. Expression_system_taxid: 562. Gene: ubc. Expression_system_taxid: 562
|
|
|
Chains:
A, C
(231 residues)
CATH domains:
|
|
|
|
|
|
Structure of the saga ubp8(s144n)/sgf11/sus1/sgf73 dub module
|
|
|
Source: Saccharomyces cerevisiae. Baker's yeast. Organism_taxid: 559292. Strain: atcc 204508 / s288c. Gene: ubp8, ym9959.05, ymr223w. Expressed in: escherichia coli. Expression_system_taxid: 469008. Gene: sus1, ybr111w-a. Gene: sgf11, ypl047w.
|
|
|
Chain:
A
(437 residues)
CATH domains:
|
|
|
|
|
|
Crystal structure of dimeric r298a mutant of sars coronavirus main protease
|
|
|
Source: Sars coronavirus. Organism_taxid: 227859. Gene: 1a. Expressed in: escherichia coli. Expression_system_taxid: 469008.
|
|
|
Chains:
A, B
(300 residues)
CATH domains:
|
|
|
|
|
|
Diversity of ubiquitin and isg15 specificity amongst nairoviruses viral ovarian tumor domain proteases
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: ubc. Expressed in: escherichia coli. Expression_system_taxid: 469008. Dugbe virus (isolate ard44313). Dugv. Organism_taxid: 766194.
|
|
|
Chains:
A, B, C, D
(75 residues)
CATH domain:
|
|
|
|
|
|
Crystal structure of otub1 in complex with ubiquitin variant
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: otub1, otb1, otu1, hspc263. Expressed in: escherichia coli. Expression_system_taxid: 562. Gene: ubc. Expression_system_taxid: 562
|
|
|
Chain:
A
(217 residues)
CATH domains:
|
|
|
|
|
|
Equine arteritis virus papain-like protease 2 (plp2) covalently bound to ubiquitin
|
|
|
Source: Equine arteritis virus. Eav. Organism_taxid: 11047. Gene: rep, 1a-1b. Expressed in: escherichia coli. Expression_system_taxid: 562. Homo sapiens. Human. Organism_taxid: 9606.
|
|
|
Chain:
A
(127 residues)
CATH domain:
|
|
|
|
|
|
Crystal structure of usp7-ntd with an e2 enzyme
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: hausp, usp7, usp7/hausp. Expressed in: escherichia coli. Expression_system_taxid: 469008. Synthetic: yes. Other_details: synthesized peptide
|
|
|
Chain:
A
(137 residues)
CATH domain:
|
|
|
|
|
|
Crystal structure of the s18y variant of ubiquitin carboxy-terminal hydrolase l1
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: uchl1. Expressed in: escherichia coli. Expression_system_taxid: 511693.
|
|
|
Chains:
A, B
(223 residues)
CATH domain:
|
|
|
|
|
|
Crystal structure of p97/vcp n in complex with otu1 ubxl
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: vcp. Expressed in: escherichia coli. Expression_system_taxid: 562. Saccharomyces cerevisiae. Baker's yeast. Organism_taxid: 559292.
|
|
|
Chains:
C, D
(65 residues)
CATH domain:
|
|
|
|
|
|
Crystal structure of p97/vcp n in complex with otu1 ubxl
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: vcp. Expressed in: escherichia coli. Expression_system_taxid: 562. Saccharomyces cerevisiae. Baker's yeast. Organism_taxid: 559292.
|
|
|
Chain:
B
(69 residues)
CATH domain:
|
|
|
|
|
|
Crystal structure of usp7-ntd with mcm-bp
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: hausp, usp7. Expressed in: escherichia coli. Expression_system_taxid: 511693. Synthetic: yes. Organism_taxid: 9606
|
|
|
Chain:
A
(138 residues)
CATH domain:
|
|
|
|
|
|
Crystal structure of the otu domain of gumby/fam105b at 1.6 angstrom
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: fam105b. Expressed in: escherichia coli. Expression_system_taxid: 469008.
|
|
|
Chain:
A
(259 residues)
|
|
|
|
|
|
Gumby/fam105b in complex with ubiquitin
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: fam105b. Expressed in: escherichia coli. Expression_system_taxid: 469008. Gene: ubc.
|
|
|
Chains:
A, B
(260 residues)
|
|
|
|
|
|
Gumby/fam105b in complex with linear di-ubiquitin
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: fam105b. Expressed in: escherichia coli. Expression_system_taxid: 469008. Gene: ubc.
|
|
|
Chains:
A, B, E, G, I, K, M, O, Q, S, U, W
(263 residues)
|
|
|
|
|
|
The structure of h/ceotub1-ubiquitin aldehyde-ubch5b~ub
|
|
|
Source: Homo sapiens, caenorhabditis elegans. Human, nematode. Organism_taxid: 9606, 6239. Gene: otub1, otb1, otu1, hspc263, c25d7.8, otub-1. Expressed in: escherichia coli. Expression_system_taxid: 562. Homo sapiens. Human. Organism_taxid: 9606.
|
|
|
Chain:
A
(255 residues)
CATH domains:
|
|
|
|
|
|
Crystal structure of sars-cov papain-like protease c112s mutant in complex with ubiquitin
|
|
|
Source: Sars coronavirus. Sars-cov. Organism_taxid: 227859. Gene: 1a, nsp3. Expressed in: escherichia coli. Expression_system_taxid: 562. Bos taurus. Bovine. Organism_taxid: 9913.
|
|
|
Chain:
A
(317 residues)
CATH domains:
|
|
|
|
|
|
Crystal structure of the usp7/hausp catalytic domain
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: usp7, hausp. Expressed in: escherichia coli. Expression_system_taxid: 562
|
|
|
Chain:
A
(343 residues)
CATH domains:
Unassigned
|
|
|
|
|
|
Crystal structure of the usp7/hausp catalytic domain
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: usp7, hausp. Expressed in: escherichia coli. Expression_system_taxid: 562
|
|
|
Chains:
A, B
(339 residues)
CATH domains:
Unassigned
|
|
|
|
|
|
Discovery of n-(benzo[1,2,3]triazol-1-yl)-n-(benzyl)acetamido)phenyl) carboxamides as severe acute respiratory syndrome coronavirus (sars- cov) 3clpro inhibitors: identification of ml300 and non-covalent nanomolar inhibitors with an induced-fit binding
|
|
|
Source: Sars coronavirus. Sars-cov. Organism_taxid: 227859. Gene: 1a. Expressed in: escherichia coli. Expression_system_taxid: 562
|
|
|
Chain:
A
(303 residues)
CATH domains:
|
|
|
|
|
|
Crystal structure of the human usp11 dusp-ubl domains
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Strain: 9606. Gene: uhx1, usp11. Expressed in: escherichia coli. Expression_system_taxid: 469008.
|
|
|
Chains:
A, B
(213 residues)
CATH domains:
|
|
|
|
|
|
Crystal structure of the rat usp11 dusp-ubl domains
|
|
|
Source: Rattus norvegicus. Brown rat,rat,rats. Organism_taxid: 10116. Strain: 10116. Gene: rcg_42884, usp11. Expressed in: escherichia coli. Expression_system_taxid: 469008.
|
|
|
Chains:
A, B
(212 residues)
CATH domains:
|
|
|
|
|
|
Crystal structure of sars-cov papain-like protease plpro in complex with ubiquitin aldehyde
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: ubc. Expressed in: escherichia coli. Expression_system_taxid: 562. Sars coronavirus. Sars-cov. Organism_taxid: 227859.
|
|
|
Chain:
B
(316 residues)
CATH domains:
|
|
|
|
|
|
Crystal structure of arterivirus nonstructural protein 10 (helicase)
|
|
|
Source: Equine arteritis virus. Eav. Organism_taxid: 299386. Strain: equine arteritis virus. Gene: 1a-1b, nsp10, rep. Expressed in: escherichia coli. Expression_system_taxid: 562.
|
|
|
Chain:
A
(401 residues)
|
|
|
|
|
|
Complex structure of arterivirus nonstructural protein 10 (helicase) with DNA
|
|
|
Source: Equine arteritis virus. Eav. Organism_taxid: 299386. Strain: equine arteritis virus. Gene: 1a-1b, nsp10, rep. Expressed in: escherichia coli. Expression_system_taxid: 562. Synthetic: yes
|
|
|
Chains:
A, C, E, G
(395 residues)
|
|
|
|
|
|
Zinc-bound rpn11 in complex with rpn8
|
|
|
Source: Saccharomyces cerevisiae. Baker's yeast. Organism_taxid: 559292. Strain: atcc 204508 / s288c. Gene: rpn8, yor261c, o5360. Expressed in: escherichia coli. Expression_system_taxid: 562. Gene: rpn11, mpr1, yfr004w. Expression_system_taxid: 562
|
|
|
Chain:
B
(166 residues)
CATH domain:
|
|
|
|
|
|
Zinc-free rpn11 in complex with rpn8
|
|
|
Source: Saccharomyces cerevisiae. Baker's yeast. Organism_taxid: 559292. Strain: atcc 204508 / s288c. Gene: rpn8, yor261c, o5360. Expressed in: escherichia coli. Expression_system_taxid: 562. Gene: rpn11, mpr1, yfr004w. Expression_system_taxid: 562
|
|
|
Chain:
B
(166 residues)
CATH domain:
|
|
|
|
|
|
Crystal structure of the rpn8-rpn11 mpn domain heterodimer, crystal form ia
|
|
|
Source: Saccharomyces cerevisiae. Baker's yeast. Organism_taxid: 559292. Strain: atcc 204508 / s288c. Gene: o5360, rpn8, yor261c. Expressed in: escherichia coli. Expression_system_taxid: 469008. Gene: mpr1, rpn11, yfr004w. Lama glama.
|
|
|
Chains:
B, E
(181 residues)
CATH domain:
|
|
|
|
|
|
Crystal structure of the rpn8-rpn11 mpn domain heterodimer, crystal form ib
|
|
|
Source: Saccharomyces cerevisiae. Baker's yeast. Organism_taxid: 559292. Strain: atcc 204508 / s288c. Gene: o5360, rpn8, yor261c. Expressed in: escherichia coli. Expression_system_taxid: 469008. Gene: mpr1, rpn11, yfr004w. Lama glama.
|
|
|
Chains:
B, E
(177 residues)
CATH domain:
|
|
|
|
|
|
Crystal structure of the rpn8-rpn11 mpn domain heterodimer, crystal form ii
|
|
|
Source: Saccharomyces cerevisiae. Baker's yeast. Organism_taxid: 559292. Strain: atcc 204508 / s288c. Gene: o5360, rpn8, yor261c. Expressed in: escherichia coli. Expression_system_taxid: 469008. Gene: mpr1, rpn11, yfr004w. Lama glama.
|
|
|
Chains:
B, E
(165 residues)
CATH domain:
|
|
|
|
|
|
X-ray structural and biological evaluation of a series of potent and highly selective inhibitors of human coronavirus papain-like proteases
|
|
|
Source: Sars coronavirus. Organism_taxid: 228330. Strain: urbani. Expressed in: escherichia coli. Expression_system_taxid: 469008.
|
|
|
Chains:
A, B
(305 residues)
CATH domains:
|
|
|
|
|
|
X-ray structural and biological evaluation of a series of potent and highly selective inhibitors of human coronavirus papain-like proteases
|
|
|
Source: Sars coronavirus. Organism_taxid: 228330. Strain: urbani. Expressed in: escherichia coli. Expression_system_taxid: 469008.
|
|
|
Chains:
A, B
(312 residues)
CATH domains:
|
|
|
|
|
|
Crystal structure of rpn11 in a heterodimer complex with rpn8, representing the active portion of the proteasome lid.
|
|
|
Source: Saccharomyces cerevisiae. Baker's yeast. Organism_taxid: 559292. Strain: atcc 204508 / s288c. Gene: o5360,rpn8,yor261c. Expressed in: escherichia coli. Expression_system_taxid: 562. Gene: mpr1,rpn11,yfr004w.
|
|
|
Chain:
B
(166 residues)
CATH domain:
|
|
|
|
|
|
Structure of hoip pub domain bound to otulin pim
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: rnf31,zibra. Expressed in: escherichia coli. Expression_system_taxid: 469008. Synthetic: yes. Organism_taxid: 9606
|
|
|
Chains:
C, D
(13 residues)
|
|
|
|
|
|
Crystal structure of the papain-like protease of middle-east respiratory syndrome coronavirus
|
|
|
Source: Human betacoronavirus 2c emc/2012. Organism_taxid: 1235996. Gene: orf1ab. Expressed in: e.Coli-k.Pastoris shuttle vector pppb1gap. Expression_system_taxid: 1182033
|
|
|
Chain:
A
(315 residues)
CATH domains:
|
|
|
|
|
|
Crystal structure of plpro from middle east respiratory syndrome (mers) coronavirus
|
|
|
Source: Human betacoronavirus 2c emc/2012. Middle east respiratory syndrome coronavirus, mers- coronavirus. Organism_taxid: 1235996. Gene: orf1ab. Expressed in: escherichia coli. Expression_system_taxid: 511693.
|
|
|
Chain:
A
(321 residues)
CATH domains:
|
|
|
|
|
|
Crystal structure of the first two ubl domains of deubiquitylase usp7
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: usp7, hausp. Expressed in: escherichia coli. Expression_system_taxid: 469008.
|
|
|
Chains:
A, B
(263 residues)
CATH domains:
Unassigned
|
|
|
|
|
|
Crystal structure of mers coronavirus papain like protease
|
|
|
Source: Betacoronavirus england 1. Hcov-emc. Organism_taxid: 1263720. Gene: 1a. Expressed in: escherichia coli bl21(de3). Expression_system_taxid: 469008
|
|
|
Chains:
B, A
(320 residues)
CATH domains:
|
|
|
|
|
|
Crystal structure of the middle-east respiratory syndrome coronavirus papain-like protease
|
|
|
Source: Human betacoronavirus 2c jordan-n3/2012. Organism_taxid: 1306931. Gene: orf1ab. Expressed in: escherichia coli. Expression_system_taxid: 562
|
|
|
Chain:
A
(311 residues)
CATH domains:
|
|
|
|
|
|
Crystal structure of the middle-east respiratory syndrome coronavirus papain-like protease in complex with ubiquitin (space group p6522)
|
|
|
Source: Human betacoronavirus 2c jordan-n3/2012. Organism_taxid: 1306931. Gene: orf1ab. Expressed in: escherichia coli. Expression_system_taxid: 562. Homo sapiens. Human. Organism_taxid: 9606. Gene: uba52, ubcep2.
|
|
|
Chain:
A
(318 residues)
CATH domains:
|
|
|
|
|
|
Crystal structure of the middle-east respiratory syndrome coronavirus papain-like protease in complex with ubiquitin (space group p63)
|
|
|
Source: Human betacoronavirus 2c jordan-n3/2012. Organism_taxid: 1306931. Gene: orf1ab. Expressed in: escherichia coli. Expression_system_taxid: 562. Homo sapiens. Human. Organism_taxid: 9606. Gene: uba52, ubcep2.
|
|
|
Chain:
A
(319 residues)
CATH domains:
|
|
|
|
|
|
Crystal structure of plpro from middle east respiratory syndrome (mers) coronavirus
|
|
|
Source: Human betacoronavirus 2c emc/2012. Organism_taxid: 1235996. Gene: orf1ab. Expressed in: escherichia coli bl21. Expression_system_taxid: 511693.
|
|
|
Chain:
A
(321 residues)
CATH domains:
|
|
|
|
|
|
Crystal structure and mutational analysis of the endoribonuclease from human coronavirus 229e
|
|
|
Source: Human coronavirus 229e. Hcov-229e. Organism_taxid: 11137. Gene: rep, 1a-1b. Expressed in: escherichia coli. Expression_system_taxid: 562
|
|
|
Chains:
A, B, C, D, E, F
(341 residues)
CATH domains:
|
|
|
|
|
|
X-ray structure of mers-cov nsp5 protease bound with a designed inhibitor
|
|
|
Source: Middle east respiratory syndrome coronavirus. Organism_taxid: 1335626. Gene: orf1a. Expressed in: escherichia coli. Expression_system_taxid: 469008. Synthetic: yes. Other_details: the peptide inhibitor was chemically synthesized in the lab.
|
|
|
Chain:
A
(304 residues)
CATH domains:
|
|
|
|
|
|
Crystal structure of the n-terminal domain of human ubiquitin specific protease 38
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: usp38, kiaa1891. Expressed in: escherichia coli. Expression_system_taxid: 469008.
|
|
|
Chain:
A
(426 residues)
|
|
|
|
|
|
Crystal structure of the mutant i26a/n52a of the endoribonuclease from human coronavirus 229e
|
|
|
Source: Human coronavirus 229e. Hcov-229e. Organism_taxid: 11137. Gene: rep, 1a-1b. Expressed in: escherichia coli. Expression_system_taxid: 562
|
|
|
Chains:
A, B, C, D, E, F
(342 residues)
CATH domains:
|
|
|
|
|
|
Crystal structure of trabid nzf1 in complex with k29 linked di- ubiquitin
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: uba52, ubcep2, zranb1. Expressed in: escherichia coli. Expression_system_taxid: 469008. Bos taurus. Bovine,cow,domestic cattle,domestic cow. Organism_taxid: 9913.
|
|
|
Chains:
F, G, H, J, I
(27 residues)
|
|
|
|
|
|
Crystal structure of fragment 1600-1733 of hsv1 ul36 in the presence of 1m potassium iodide
|
|
|
Source: Human herpesvirus 1(type 1 / strain 17). Hhv-1. Organism_taxid: 10299. Expressed in: escherichia coli. Expression_system_taxid: 562
|
|
|
Chains:
A, B
(129 residues)
|
|
|
|
|
|
Crystal structure of fragment 1600-1733 of hsv1 ul36, native
|
|
|
Source: Herpes simplex virus (type 1 / strain 17). Hhv-1. Organism_taxid: 10299. Gene: ul36. Expressed in: escherichia coli. Expression_system_taxid: 562
|
|
|
Chains:
A, B
(124 residues)
|
|
|
|
|
|
Structure of sars-3cl protease complex with a bromobenzoyl (s,r)-n- decalin type inhibitor
|
|
|
Source: Human sars coronavirus. Sars-cov. Organism_taxid: 227859. Expressed in: escherichia coli bl21(de3). Expression_system_taxid: 469008.
|
|
|
Chains:
A, B
(306 residues)
CATH domains:
|
|
|
|
|
|
Structure of sars-3cl protease complex with a phenylbenzoyl (s,r)-n- decalin type inhibitor
|
|
|
Source: Human sars coronavirus. Sars-cov. Organism_taxid: 227859. Gene: rep, 1a-1b. Expressed in: escherichia coli bl21(de3). Expression_system_taxid: 469008.
|
|
|
Chain:
A
(306 residues)
CATH domains:
|
|
|
|
|
|
Uch-l5 in complex with ubiquitin-propargyl bound to the rpn13 deubad domain
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Variant: isoform 3. Expressed in: escherichia coli. Expression_system_taxid: 469008. Expression_system_variant: rosetta 2. Synthetic: yes.
|
|
|
Chain:
A
(302 residues)
CATH domains:
|
|
|
|
|
|
Uch-l5 in complex with the rpn13 deubad domain
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Expressed in: escherichia coli. Expression_system_taxid: 469008. Expression_system_variant: rosetta 2.
|
|
|
Chain:
A
(281 residues)
CATH domains:
|
|
|
|
|
|
Crystal structure of uch-l5 in complex with inhibitory fragment of ino80g
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Expressed in: escherichia coli. Expression_system_taxid: 469008. Expression_system_variant: rosetta 2.
|
|
|
Chain:
A
(293 residues)
|
|
|
|
|
|
Uch-l5 in complex with ubiquitin-propargyl bound to an activating fragment of ino80g
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Expressed in: escherichia coli. Expression_system_taxid: 469008. Expression_system_variant: rosetta 2. Synthetic: yes.
|
|
|
Chains:
A, D, G, J
(292 residues)
|
|
|
|
|
|
Structure of yeast saga dubm with sgf73 y57a mutant at 2.8 angstroms resolution
|
|
|
Source: Saccharomyces cerevisiae. Baker's yeast. Organism_taxid: 889517. Strain: cen.Pk113-7d. Gene: cenpk1137d_262. Expressed in: escherichia coli. Expression_system_taxid: 562. Gene: sus1, cenpk1137d_4659. Gene: sgf11, cenpk1137d_1654.
|
|
|
Chains:
A, D
(438 residues)
CATH domains:
|
|
|
|
|
|
Structure of yeast saga dubm with sgf73 n59d mutant at 2.36 angstroms resolution
|
|
|
Source: Saccharomyces cerevisiae. Baker's yeast. Organism_taxid: 559292. Strain: atcc 204508 / s288c. Gene: ubp8, ymr223w, ym9959.05. Expressed in: escherichia coli. Expression_system_taxid: 562. Gene: sus1, ybr111w-a. Organism_taxid: 307796.
|
|
|
Chains:
A, D
(440 residues)
CATH domains:
|
|
|
|
|
|
Crystal structure of uch37-nfrkb inhibited deubiquitylating complex
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: uchl5, uch37, ad-019, cgi-70. Expressed in: escherichia coli. Expression_system_taxid: 562. Gene: nfrkb, ino80g. Expression_system_taxid: 562
|
|
|
Chain:
A
(296 residues)
|
|
|
|
|
|
Crystal structure of much37-hrpn13 ctd complex
|
|
|
Source: Mus musculus. Mouse. Organism_taxid: 10090. Gene: uchl5, uch37. Expressed in: escherichia coli. Expression_system_taxid: 562. Homo sapiens. Human. Organism_taxid: 9606.
|
|
|
Chain:
A
(292 residues)
|
|
|
|
|
|
Crystal structure of much37-hrpn13 ctd-hub complex
|
|
|
Source: Mus musculus. Mouse. Organism_taxid: 10090. Gene: uchl5, uch37. Expressed in: escherichia coli. Expression_system_taxid: 562. Homo sapiens. Human. Organism_taxid: 9606.
|
|
|
Chain:
A
(296 residues)
|
|
|
|
|
|
Crystal structure of catalytically inactive mers-cov 3cl protease (c148a) in spacegroup c2221
|
|
|
Source: Middle east respiratory syndrome coronavirus. Organism_taxid: 1335626. Expressed in: escherichia coli. Expression_system_taxid: 562.
|
|
|
Chains:
A, B, C
(301 residues)
CATH domains:
|
|
|
|
|
|
Crystal structure of catalytically inactive mers-cov 3cl protease (c148a) in spacegroup c2
|
|
|
Source: Middle east respiratory syndrome coronavirus. Organism_taxid: 1335626. Expressed in: escherichia coli. Expression_system_taxid: 562.
|
|
|
Chains:
A, B, C, D
(306 residues)
CATH domains:
|
|
|
|
|
|
Crystal structure of catalytically inactive mers-cov 3cl protease (c148a) in spacegroup p212121
|
|
|
Source: Middle east respiratory syndrome coronavirus. Organism_taxid: 1335626. Expressed in: escherichia coli. Expression_system_taxid: 562.
|
|
|
Chains:
A, B, C
(304 residues)
CATH domains:
|
|
|
|
|
|
Crystal structure of usp7 ubiquitin-like domains in compact conformation
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: usp7, hausp. Expressed in: escherichia coli. Expression_system_taxid: 469008. Synthetic: yes. Herpes simplex virus (type 1 / strain 17). Organism_taxid: 10299
|
|
|
Chains:
A, B
(337 residues)
|
|
|
|
|
|
Crystal structure of usp7 ubiquitin-like domains in extended conformation
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: usp7, hausp. Expressed in: escherichia coli. Expression_system_taxid: 469008. Synthetic: yes. Herpes simplex virus (type 1 / strain 17). Organism_taxid: 10299
|
|
|
Chains:
A, B
(341 residues)
|
|
|
|
|
|
Ataxin-3 carboxy terminal region - crystal c2 (triclinic)
|
|
|
Source: Escherichia coli, homo sapiens. Human. Organism_taxid: 562, 9606. Gene: male, z5632, ecs5017, atxn3, atx3, mjd, mjd1, sca3. Expressed in: escherichia coli bl21(de3). Expression_system_taxid: 469008
|
|
|
Chains:
A, B
(403 residues)
|
|
|
|
|
|
The crystal structure of the mers-cov papain-like protease (c111s) with human ubiquitin
|
|
|
Source: Human coronavirus emc. Hcov-emc. Organism_taxid: 1263720. Strain: isolate united kingdom/h123990006/2012. Gene: rep, 1a-1b. Expressed in: escherichia coli bl21(de3). Expression_system_taxid: 469008. Expression_system_variant: tuner placi. Homo sapiens.
|
|
|
Chain:
A
(317 residues)
CATH domains:
|
|
|
|
|
|
Structure of sars-3cl protease complex with a phenylbenzoyl (r,s)-n- decalin type inhibitor
|
|
|
Source: Sars coronavirus. Sars-cov. Organism_taxid: 227859. Gene: rep, 1a-1b. Expressed in: escherichia coli. Expression_system_taxid: 469008.
|
|
|
Chain:
A
(306 residues)
CATH domains:
|
|
|
|
|
|
Structural view and substrate specificity of papain-like protease from avian infectious bronchitis virus
|
|
|
Source: Avian infectious bronchitis virus. Ibv. Organism_taxid: 11122. Strain: beaudette. Gene: rep, 1a-1b. Expressed in: escherichia coli. Expression_system_taxid: 562
|
|
|
Chain:
A
(301 residues)
|
|
|
|
|
|
Crystal structure of siah1 sina domain in complex with a usp19 peptide
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: siah1, humsiah. Expressed in: escherichia coli. Expression_system_taxid: 469008. Expression_system_variant: v2r-prare2. Synthetic: yes. Organism_taxid: 9606
|
|
|
Chain:
C
(11 residues)
|
|
|
|
|
|
Crystal structure basis for pedv 3c like protease
|
|
|
Source: Porcine epidemic diarrhea virus. Organism_taxid: 28295. Gene: pol1. Expressed in: escherichia coli. Expression_system_taxid: 511693.
|
|
|
Chains:
A, B
(298 residues)
CATH domains:
|
|
|
|
|
|
X-ray structure of mers-cov nsp5 protease bound with a non-covalent inhibitor
|
|
|
Source: Middle east respiratory syndrome coronavirus. Organism_taxid: 1335626. Gene: orf1ab. Expressed in: escherichia coli. Expression_system_taxid: 469008.
|
|
|
Chains:
A, B, C, D
(304 residues)
CATH domains:
|
|
|
|
|
|
Hku4 3clpro unbound structure
|
|
|
Source: Bat coronavirus hku4. Btcov. Organism_taxid: 694007. Gene: rep, 1a-1b. Expressed in: escherichia coli. Expression_system_taxid: 562
|
|
|
Chains:
A, B
(306 residues)
CATH domains:
|
|
|
|
|
|
Crystal structure of human dnmt1 and usp7/hausp complex
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: dnmt1, aim, cxxc9, dnmt. Expressed in: escherichia coli. Expression_system_taxid: 562. Gene: usp7, hausp. Expression_system_taxid: 562
|
|
|
Chain:
C
(529 residues)
|
|
|
|
|
|
Hku4-3clpro bound to non-covalent inhibitor 3b
|
|
|
Source: Bat coronavirus hku4. Btcov. Organism_taxid: 694007. Gene: rep, 1a-1b. Expressed in: escherichia coli. Expression_system_taxid: 562
|
|
|
Chains:
A, B
(306 residues)
CATH domains:
|
|
|
|
|
|
Structure of hku4 3clpro bound to non-covalent inhibitor 1a
|
|
|
Source: Bat coronavirus hku4. Btcov. Organism_taxid: 694007. Gene: rep, 1a-1b. Expressed in: escherichia coli. Expression_system_taxid: 562
|
|
|
Chains:
A, B
(306 residues)
CATH domains:
|
|
|
|
|
|
Hku4 3clpro bound to non-covalent inhibitor 2a
|
|
|
Source: Bat coronavirus hku4. Btcov. Organism_taxid: 694007. Gene: rep, 1a-1b. Expressed in: escherichia coli. Expression_system_taxid: 562
|
|
|
Chains:
A, B
(306 residues)
CATH domains:
|
|
|
|
|
|
X-ray structural of three tandemly linked domains of nsp3 from murine hepatitis virus at 2.60 angstroms resolution
|
|
|
Source: Murine coronavirus (strain a59). Mhv-a59. Organism_taxid: 11142. Strain: a59. Gene: rep, 1a-1b. Expressed in: escherichia coli. Expression_system_taxid: 562
|
|
|
Chain:
A
(378 residues)
|
|
|
|
|
|
Ataxin-3 carboxy-terminal region - crystal c1 (tetragonal)
|
|
|
Source: Escherichia coli, homo sapiens. Human, human. Organism_taxid: 562, 9606. Gene: male, z5632, ecs5017, atxn3, atx3, mjd, mjd1, sca3. Expressed in: escherichia coli bl21(de3). Expression_system_taxid: 469008
|
|
|
Chain:
B
(384 residues)
|
|
|
|
|
|
Structure of usp7 with a novel viral protein
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: usp7, hausp. Expressed in: escherichia coli. Expression_system_taxid: 562. Synthetic: yes. Human herpesvirus 8. Organism_taxid: 37296
|
|
|
Chain:
A
(138 residues)
CATH domain:
|
|
|
|
|
|
Crystal structure of dnmt1 in complex with usp7
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: usp7, hausp. Expressed in: escherichia coli. Expression_system_taxid: 562. Gene: dnmt1, aim, cxxc9, dnmt. Expression_system_taxid: 562
|
|
|
Chain:
A
(523 residues)
|
|
|
|
|
|
Crystal structure of usp7 in complex with dnmt1(k1115q)
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: usp7, hausp. Expressed in: escherichia coli. Expression_system_taxid: 562. Gene: dnmt1, aim, cxxc9, dnmt. Expression_system_taxid: 562
|
|
|
Chain:
A
(521 residues)
|
|
|
|
|
|
2.1 a x-ray structure of fipv-3clpro bound to covalent inhibitor
|
|
|
Source: Feline coronavirus (strain fipv wsu-79/1146). Fcov. Organism_taxid: 33734. Strain: fipv wsu-79/1146. Gene: rep, 1a-1b. Expressed in: escherichia coli. Expression_system_taxid: 562. Synthetic: yes. Synthetic construct.
|
|
|
Chains:
A, B, C, D
(299 residues)
CATH domains:
|
|
|
|
|
|
Complex structure of pedv 3clpro mutant (c144a) with a peptide substrate.
|
|
|
Source: Porcine epidemic diarrhea virus. Organism_taxid: 28295. Gene: pol1. Expressed in: escherichia coli. Expression_system_taxid: 511693. Synthetic: yes. Synthetic construct. Organism_taxid: 32630
|
|
|
Chains:
A, B
(298 residues)
CATH domains:
|
|
|
|
|
|
Saga dub module ubp8/sgf11/sus1/sgf73 bound to ubiqitinated nucleosome
|
|
|
Source: Xenopus laevis. African clawed frog. Organism_taxid: 8355. Expressed in: escherichia coli. Expression_system_taxid: 562. Synthetic construct. Organism_taxid: 32630. Saccharomyces cerevisiae (strain atcc 204508 / s288c).
|
|
|
Chains:
U, Z, e, j
(447 residues)
CATH domains:
|
|
|
|
|
|
Structure of the 26s proteasome-ubp6 complex
|
|
|
Source: Saccharomyces cerevisiae. Baker's yeast. Organism_taxid: 4932. Strain: yfr010w. Homo sapiens. Human. Organism_taxid: 9606. Organism_taxid: 4932
|
|
|
Chains:
8, V
(368 residues)
|
|
|
|
|
|
Structure of mammalian eif3 in the context of the 43s preinitiation complex
|
|
|
Source: Oryctolagus cuniculus. Rabbit. Organism_taxid: 9986. Cell_line: reticulcytes. Tissue: blood. Tissue: blood
|
|
|
Chain:
F
(272 residues)
|
|
|
|
|
|
Structure of lys33-linked diub bound to trabid nzf1
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Expressed in: escherichia coli. Expression_system_taxid: 469008. Expression_system_variant: rosettaii.
|
|
|
Chains:
F, G, H, I, J
(28 residues)
|
|
|
|
|
|
Crystal structure of ms8104
|
|
|
Source: Human sars coronavirus. Sars-cov. Organism_taxid: 227859. Expressed in: cell-free synthesis
|
|
|
Chains:
A, B
(310 residues)
CATH domains:
|
|
|
|
|
|
Crystal structure of ibv papain-like protease plpro c101s mutant in complex with ubiquitin
|
|
|
Source: Avian infectious bronchitis virus (strain beaudette). Ibv. Organism_taxid: 11122. Strain: beaudette. Gene: rep, 1a-1b. Expressed in: escherichia coli. Expression_system_taxid: 562. Bos taurus.
|
|
|
Chain:
A
(248 residues)
|
|
|
|
|
|
Crystal structure of mers coronavirus main protease in spacegroup c2221
|
|
|
Source: Middle east respiratory syndrome coronavirus. Organism_taxid: 1335626. Gene: orf1ab. Expressed in: escherichia coli bl21(de3). Expression_system_taxid: 469008.
|
|
|
Chains:
A, B
(301 residues)
CATH domains:
|
|
|
|
|
|
Crystal structure of usp7/hausp in complex with icp0
|
|
|
Source: Synthetic: yes. Human herpesvirus 1. Hhv-1. Organism_taxid: 10298. Homo sapiens. Human. Organism_taxid: 9606. Gene: usp7, hausp. Expressed in: escherichia coli.
|
|
|
Chain:
A
(528 residues)
|
|
|
|
|
|
Structure of sars-3cl protease complex with a phenyl-beta-alanyl (r, s)-n-decalin type inhibitor
|
|
|
Source: Human sars coronavirus. Sars-cov. Organism_taxid: 227859. Expressed in: escherichia coli bl21(de3). Expression_system_taxid: 469008.
|
|
|
Chain:
A
(306 residues)
CATH domains:
|
|
|
|
|
|
Structure of sars-3cl protease complex with a phenyl-beta-alanyl (s, r)-n-decalin type inhibitor
|
|
|
Source: Human sars coronavirus. Sars-cov. Organism_taxid: 227859. Expressed in: escherichia coli bl21(de3). Expression_system_taxid: 469008.
|
|
|
Chains:
A, B
(300 residues)
CATH domains:
|
|
|
|
|
|
Crystal structure of usp7 in complex with uhrf1
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: usp7, hausp. Expressed in: escherichia coli. Expression_system_taxid: 562. Gene: uhrf1, icbp90, np95, rnf106. Expression_system_taxid: 562
|
|
|
Chains:
A, B
(311 residues)
|
|
|
|
|
|
Crystal structure of the sars coronavirus nsp14-nsp10 complex with functional ligands sah and gpppa
|
|
|
Source: Human sars coronavirus. Sars-cov. Organism_taxid: 227859. Expressed in: escherichia coli. Expression_system_taxid: 562.
|
|
|
Chains:
A, B, C, D
(133 residues)
|
|
|
|
|
|
Crystal structure of the sars coronavirus nsp14-nsp10 complex with functional ligand sam
|
|
|
Source: Human sars coronavirus. Sars-cov. Organism_taxid: 227859. Expressed in: escherichia coli. Expression_system_taxid: 562.
|
|
|
Chains:
A, B, C, D
(133 residues)
|
|
|
|
|
|
Crystal structure of the sars coronavirus nsp14-nsp10 complex
|
|
|
Source: Human sars coronavirus. Sars-cov. Organism_taxid: 227859. Expressed in: escherichia coli. Expression_system_taxid: 562.
|
|
|
Chains:
A, B, C, D
(133 residues)
|
|
|
|
|
|
Infectious bronchitis virus nsp9
|
|
|
Source: Avian infectious bronchitis virus. Ibv. Organism_taxid: 11127. Strain: m41. Gene: rep, 1a-1b. Expressed in: escherichia coli. Expression_system_taxid: 469008.
|
|
|
Chain:
A
(116 residues)
CATH domain:
|
|
|
|
|
|
Crystal structure of usp18
|
|
|
Source: Mus musculus. Mouse. Organism_taxid: 10090. Gene: usp18, ubp43. Expressed in: spodoptera frugiperda. Expression_system_taxid: 7108. Expression_system_cell_line: sf21.
|
|
|
Chains:
A, B
(308 residues)
CATH domain:
|
|
|
|
|
|
Crystal structure of usp18-isg15 complex
|
|
|
Source: Mus musculus. Mouse. Organism_taxid: 10090. Gene: usp18, ubp43. Expressed in: spodoptera frugiperda. Expression_system_taxid: 7108. Expression_system_cell_line: sf21. Gene: isg15, g1p2, ucrp. Expressed in: escherichia coli.
|
|
|
Chains:
A, B
(304 residues)
CATH domain:
|
|
|
|
|
|
Crystal structure of human sart3 hat-c domain-human usp4 dusp-ubl domain complex
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: sart3, kiaa0156, tip110. Expressed in: escherichia coli. Expression_system_taxid: 562. Gene: usp4, unp, unph. Expression_system_taxid: 562
|
|
|
Chains:
C, D
(206 residues)
CATH domains:
|
|
|
|
|
|
Usp46~ubiquitin bea covalent complex
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: usp46. Expressed in: trichoplusia ni. Expression_system_taxid: 7111. Gene: ubb.
|
|
|
Chain:
A
(308 residues)
CATH domain:
|
|
|
|
|
|
Wdr48 (2-580):usp46~ubiquitin ternary complex
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: wdr48, kiaa1449, uaf1. Expressed in: trichoplusia ni. Expression_system_taxid: 7111. Gene: usp46. Gene: ubb.
|
|
|
Chain:
B
(321 residues)
CATH domain:
|
|
|
|
|
|
Wdr48:usp46~ubiquitin ternary complex
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: wdr48, kiaa1449, uaf1. Expressed in: trichoplusia ni. Expression_system_taxid: 7111. Gene: usp46. Gene: ubb.
|
|
|
Chains:
B, E
(321 residues)
CATH domain:
|
|
|
|
|
|
Mus musculus a20 otu domain
|
|
|
Source: Mus musculus. Mouse. Organism_taxid: 10090. Gene: tnfaip3, tnfip3. Expressed in: escherichia coli. Expression_system_taxid: 562
|
|
|
Chains:
A, B
(336 residues)
|
|
|
|
|
|
Crystal structure of mers-cov macro domain in complex with adp-ribose
|
|
|
Source: Middle east respiratory syndrome coronavirus. Organism_taxid: 1335626. Expressed in: escherichia coli bl21(de3). Expression_system_taxid: 469008.
|
|
|
Chain:
A
(165 residues)
CATH domain:
|
|
|
|
|
|
Structure of sars plpro bound to a lys48-linked di-ubiquitin activity based probe
|
|
|
Source: Human sars coronavirus. Sars-cov. Organism_taxid: 227859. Gene: rep, 1a-1b. Expressed in: escherichia coli. Expression_system_taxid: 562. Synthetic: yes. Homo sapiens. Organism_taxid: 32630.
|
|
|
Chains:
A, D
(317 residues)
CATH domains:
|
|
|
|
|
|
Structure of fipv main protease in complex with dual inhibitors
|
|
|
Source: Feline infectious peritonitis virus. Fipv. Organism_taxid: 11135. Gene: 1b, orf1a. Expressed in: escherichia coli bl21(de3). Expression_system_taxid: 469008. Synthetic: yes. Synthetic construct. Organism_taxid: 32630
|
|
|
Chain:
A
(300 residues)
CATH domains:
|
|
|
|
|
|
Structure of prrsv apo-nsp11 at 2.16a
|
|
|
Source: Prrsv 16244b. Porcine reproductive and respiratory syndrome virus 16244b. Organism_taxid: 300561. Strain: 16244b. Gene: rep, 1a-1b. Expressed in: escherichia coli. Expression_system_taxid: 562
|
|
|
Chains:
A, B
(223 residues)
|
|
|
|
|
|
Structure of eav nsp11 k170a mutant at 3.19a
|
|
|
Source: Equine arteritis virus bucyrus. Eav. Organism_taxid: 299386. Strain: bucyrus. Gene: rep, 1a-1b. Expressed in: escherichia coli. Expression_system_taxid: 562
|
|
|
Chains:
A, B, C, D, E, F
(219 residues)
|
|
|
|
|
|
C-terminal domain of sars-cov nsp8 complex with nsp7
|
|
|
Source: Sars coronavirus. Sars-cov. Organism_taxid: 227859. Gene: 1a. Expressed in: escherichia coli. Expression_system_taxid: 562. Gene: rep, 1a-1b. Expression_system_taxid: 562
|
|
|
Chains:
A, B
(79 residues)
|
|
|
|
|
|
Structure of usp7 catalytic domain and three ubl-domains
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Expressed in: escherichia coli. Expression_system_taxid: 511693.
|
|
|
Chain:
C
(662 residues)
|
|
|
|
|
|
Crystal structure of usp7 with rnf169 peptide
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: usp7, hausp. Expressed in: escherichia coli 'bl21-gold(de3)plyss ag'. Expression_system_taxid: 866768. Synthetic: yes. Organism_taxid: 9606
|
|
|
Chains:
A, B, C, D
(313 residues)
|
|
|
|
|
|
Structure of the human 26s proteasome bound to usp14-ubal
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: usp14, tgt. Expressed in: escherichia coli k-12. Expression_system_taxid: 83333. Gene: ubb. Expressed in: escherichia coli. Expression_system_taxid: 562
|
|
|
Chain:
x
(355 residues)
|
|
|
|
|
|
Structure of main protease from human coronavirus nl63: insights for wide spectrum anti-coronavirus drug design
|
|
|
Source: Human coronavirus nl63. Hcov-nl63. Organism_taxid: 277944. Gene: 1a. Expressed in: escherichia coli. Expression_system_taxid: 562. Synthetic: yes. Synthetic construct. Organism_taxid: 32630
|
|
|
Chains:
A, B
(298 residues)
|
|
|
|
|
|
The structure of porcine epidemic diarrhea virus main protease in complex with an inhibitor
|
|
|
Source: Porcine epidemic diarrhea virus cv777. Pedv. Organism_taxid: 229032. Strain: cv777. Gene: 1a. Expressed in: escherichia coli. Expression_system_taxid: 562. Synthetic: yes. Synthetic construct.
|
|
|
Chains:
B, A
(299 residues)
CATH domains:
|
|
|
|
|
|
Structure of eav nsp11 k170a mutant at 3.10a
|
|
|
Source: Equine arteritis virus bucyrus. Eav. Organism_taxid: 299386. Strain: bucyrus. Gene: rep, 1a-1b. Expressed in: escherichia coli. Expression_system_taxid: 562
|
|
|
Chains:
A, B, C, D, E, F
(219 residues)
|
|
|
|
|
|
Structure of eav nsp11 h141a mutant at 3.10a
|
|
|
Source: Equine arteritis virus bucyrus. Eav. Organism_taxid: 299386. Strain: bucyrus. Gene: rep, 1a-1b. Expressed in: escherichia coli. Expression_system_taxid: 562
|
|
|
Chains:
A, B, C, D
(219 residues)
|
|
|
|
|
|
Crystal structure of the macro domain in middle-east respiratory syndrome coronavirus
|
|
|
Source: Middle east respiratory syndrome coronavirus. Organism_taxid: 1335626. Expressed in: escherichia coli bl21(de3). Expression_system_taxid: 469008. Expression_system_variant: tuner placi.
|
|
|
Chain:
A
(167 residues)
CATH domain:
|
|
|
|
|
|
Crystal structure of pedv nsp9 mutant-c59a
|
|
|
Source: Porcine epidemic diarrhea virus cv777. Pedv. Organism_taxid: 229032. Strain: cv777. Gene: rep, 1a-1b. Expressed in: escherichia coli 'bl21-gold(de3)plyss ag'. Expression_system_taxid: 866768.
|
|
|
Chains:
A, B, C
(95 residues)
CATH domain:
|
|
|
|
|
|
The structure of pedv nsp9
|
|
|
Source: Porcine epidemic diarrhea virus cv777. Pedv. Organism_taxid: 229032. Strain: cv777. Gene: rep, 1a-1b. Expressed in: escherichia coli 'bl21-gold(de3)plyss ag'. Expression_system_taxid: 866768.
|
|
|
Chains:
A, B
(96 residues)
CATH domain:
|
|
|
|
|
|
The crystal structure of the mers-cov macro domain with adp-ribose
|
|
|
Source: Middle east respiratory syndrome coronavirus. Organism_taxid: 1335626. Expressed in: escherichia coli bl21(de3). Expression_system_taxid: 469008. Expression_system_variant: tuner placi.
|
|
|
Chain:
A
(167 residues)
CATH domain:
|
|
|
|
|
|
X-ray structure of unbound porcine epidemic diarrhea virus 3clpro
|
|
|
Source: Porcine epidemic diarrhea virus. Organism_taxid: 28295. Expressed in: escherichia coli. Expression_system_taxid: 562
|
|
|
Chains:
A, B
(301 residues)
CATH domains:
|
|
|
|
|
|
Porcine reproductive and respiratory syndrome virus nonstructural protein 7 alpha (nsp7 alpha)
|
|
|
Source: Porcine reproductive and respiratory syndrome virus. Prrsv. Organism_taxid: 28344. Expressed in: escherichia coli. Expression_system_taxid: 562
|
|
|
Chain:
A
(150 residues)
|
|
|
|
|
|
Molecular understanding of usp7 substrate recognition and c-terminal activation
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: usp7, hausp. Expressed in: escherichia coli. Expression_system_taxid: 562
|
|
|
Chain:
A
(671 residues)
|
|
|
|
|
|
Crystal structure of the hat domain of sart3 in complex with usp15 dusp-ubl domain
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: sart3, kiaa0156, tip110. Expressed in: escherichia coli. Expression_system_taxid: 562. Gene: usp15, kiaa0529.
|
|
|
Chain:
B
(149 residues)
|
|
|
|
|
|
Crystal structure of deubiquitinase mindy-1
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: fam63a, kiaa1390. Expressed in: escherichia coli. Expression_system_taxid: 469008.
|
|
|
Chain:
A
(256 residues)
|
|
|
|
|
|
Crystal structure of deubiquitinase mindy-1 in complex with ubiquitin
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: fam63a, kiaa1390. Expressed in: escherichia coli. Expression_system_taxid: 562. Bos taurus. Bovine. Organism_taxid: 9913.
|
|
|
Chain:
A
(251 residues)
|
|
|
|
|
|
Usp7cd-ctp in complex with ubiquitin
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: usp7, hausp. Expressed in: escherichia coli. Expression_system_taxid: 562. Gene: ubb. Expression_system_taxid: 562
|
|
|
Chain:
A
(356 residues)
|
|
|
|
|
|
Usp7cd-ubl45 in complex with ubiquitin
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: usp7, hausp. Expressed in: escherichia coli. Expression_system_taxid: 562. Gene: ubb. Expression_system_taxid: 562
|
|
|
Chains:
A, C, E, G
(564 residues)
|
|
|
|
|
|
Crystal structure of free ubiquitin-specific protease 12
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: usp12, ubh1, usp12l1. Expressed in: escherichia coli k-12. Expression_system_taxid: 83333
|
|
|
Chains:
A, B
(324 residues)
CATH domain:
|
|
|
|
|
|
Crystal structure of the uaf1-usp12 complex in c2 space group
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: usp12, ubh1, usp12l1. Expressed in: escherichia coli k-12. Expression_system_taxid: 83333. Gene: wdr48, kiaa1449, uaf1. Expression_system_taxid: 83333
|
|
|
Chains:
A, C, E, G
(239 residues)
|
|
|
|
|
|
Crystal structure of the uaf1/usp12 complex in f222 space group
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: wdr48, kiaa1449, uaf1. Expressed in: escherichia coli k-12. Expression_system_taxid: 83333. Gene: usp12, ubh1, usp12l1. Expression_system_taxid: 83333
|
|
|
Chain:
A
(264 residues)
|
|
|
|
|
|
Crystal structure of the uaf1/wdr20/usp12 complex
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: usp12, ubh1, usp12l1. Expressed in: baculovirus expression vector pfastbac1-hm. Expression_system_taxid: 274590. Gene: wdr48, kiaa1449, uaf1. Gene: wdr20. Expressed in: escherichia coli k-12.
|
|
|
Chain:
A
(302 residues)
|
|
|
|
|
|
Structure of a core papain-like protease of mers coronavirus with utility for structure-based drug design
|
|
|
Source: Middle east respiratory syndrome coronavirus. Organism_taxid: 1335626. Expressed in: escherichia coli. Expression_system_taxid: 562
|
|
|
Chain:
A
(257 residues)
CATH domains:
|
|
|
|
|
|
Crystal structure of the apo-form of usp7 catalytic domain [v302k] mutant
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: usp7, hausp. Expressed in: escherichia coli. Expression_system_taxid: 562
|
|
|
Chains:
A, B
(330 residues)
|
|
|
|
|
|
Crystal structure of usp7 catalytic domain [v302k] mutant in complex with ubiquitin (malonate bound)
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: usp7, hausp. Expressed in: escherichia coli. Expression_system_taxid: 562. Gene: ubb. Expression_system_taxid: 562
|
|
|
Chain:
B
(340 residues)
|
|
|
|
|
|
Crystal structure of usp7 catalytic domain [v302k] mutant in complex with ubiquitin
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: ubb. Expressed in: escherichia coli. Expression_system_taxid: 562. Gene: usp7, hausp. Expression_system_taxid: 562
|
|
|
Chain:
A
(341 residues)
|
|
|
|
|
|
Crystal structure of usp7 catalytic domain [h294e] mutant in complex with ubiquitin
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: usp7, hausp. Expressed in: escherichia coli. Expression_system_taxid: 562. Gene: ubb. Expression_system_taxid: 562
|
|
|
Chains:
A, B
(343 residues)
|
|
|
|
|
|
Crystal structure of usp7 catalytic domain [l299a] mutant in complex with ubiquitin
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: usp7, hausp. Expressed in: escherichia coli. Expression_system_taxid: 562. Gene: ubb. Expression_system_taxid: 562
|
|
|
Chain:
B
(340 residues)
|
|
|
|
|
|
Structure of usp46-ubvme
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: usp46. Expressed in: escherichia coli. Expression_system_taxid: 562. Gene: ubb. Expression_system_taxid: 562
|
|
|
Chain:
A
(311 residues)
|
|
|
|
|
|
Structure of usp12-ub-prg/uaf1
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: usp12, ubh1, usp12l1. Expressed in: spodoptera frugiperda. Expression_system_taxid: 7108. Gene: wdr48, kiaa1449, uaf1. Gene: ubb. Expressed in: escherichia coli.
|
|
|
Chain:
A
(319 residues)
|
|
|
|
|
|
Structure of cezanne/otud7b otu domain
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: otud7b, za20d1. Expressed in: escherichia coli. Expression_system_taxid: 562
|
|
|
Chain:
A
(280 residues)
|
|
|
|
|
|
Structure of cezanne/otud7b otu domain bound to lys11-linked diubiquitin
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: otud7b, za20d1. Expressed in: escherichia coli. Expression_system_taxid: 562. Synthetic: yes. Organism_taxid: 9606
|
|
|
Chain:
A
(286 residues)
|
|
|
|
|
|
Structure of cezanne/otud7b otu domain bound to ubiquitin
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: otud7b, za20d1. Expressed in: escherichia coli. Expression_system_taxid: 562. Gene: ubb. Expression_system_taxid: 562
|
|
|
Chains:
A, C
(278 residues)
|
|
|
|
|
|
Structure of a20 otu domain bound to ubiquitin
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: tnfaip3, otud7c. Expressed in: escherichia coli. Expression_system_taxid: 562. Gene: ubb. Expression_system_taxid: 562
|
|
|
Chains:
A, C, E, F
(348 residues)
|
|
|
|
|
|
Turnip yellow mosaic virus protease/deubiquitinase domain, deltac5 mutant
|
|
|
Source: Turnip yellow mosaic virus. Organism_taxid: 12154. Expressed in: escherichia coli. Expression_system_taxid: 562
|
|
|
Chains:
A, B
(145 residues)
|
|
|
|
|
|
Turnip yellow mosaic virus protease/deubiquitinase domain, i847a mutant
|
|
|
Source: Turnip yellow mosaic virus. Organism_taxid: 12154. Expressed in: escherichia coli. Expression_system_taxid: 562
|
|
|
Chains:
A, B
(148 residues)
|
|
|
|
|
|
Crystal structure of mindy-1 tmiu in complex with k48-diub
|
|
|
Source: Bos taurus. Bovine. Organism_taxid: 9913. Homo sapiens. Human. Organism_taxid: 9606. Gene: fam63a, kiaa1390. Expressed in: escherichia coli bl21(de3). Expression_system_taxid: 469008
|
|
|
Chain:
C
(19 residues)
|
|
|
|
|
|
26s proteasome in presence of atp (s1)
|
|
|
Source: Saccharomyces cerevisiae (strain atcc 204508 / s288c). Baker's yeast. Organism_taxid: 559292. Organism_taxid: 559292
|
|
|
Chain:
V
(289 residues)
|
|
|
|
|
|
26s proteasome in presence of atp (s2)
|
|
|
Source: Saccharomyces cerevisiae (strain atcc 204508 / s288c). Organism_taxid: 559292. Organism_taxid: 559292
|
|
|
Chain:
V
(289 residues)
|
|
|
|
|
|
Structure of sars coronavirus main protease in complex with the alpha- ketoamide (s)-n-benzyl-3-((s)-2-cinnamamido-3-phenylpropanamido)-2- oxo-4-((s)-2-oxopyrrolidin-3-yl)butanamide
|
|
|
Source: Human sars coronavirus. Sars-cov. Organism_taxid: 227859. Gene: rep, 1a-1b. Expressed in: escherichia coli. Expression_system_taxid: 562
|
|
|
Chain:
A
(306 residues)
|
|
|
|
|
|
Structure of sars coronavirus main protease in complex with the alpha- ketoamide (s)-n-benzyl-3-((s)-2-cinnamamido-3- cyclopropylpropanamido)-2-oxo-4-((s)-2-oxopyrrolidin-3-yl)butanamide (cinnamoyl-cyclopropylalanine-glnlactam-co-co-nh-benzyl)
|
|
|
Source: Sars coronavirus. Organism_taxid: 227859. Gene: rep, 1a-1b. Expressed in: escherichia coli. Expression_system_taxid: 562
|
|
|
Chain:
A
(306 residues)
|
|
|
|
|
|
Crystal structure of usp7 in complex with a potent, selective and reversible small-molecule inhibitor
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: usp7, hausp. Expressed in: escherichia coli. Expression_system_taxid: 562
|
|
|
Chains:
A, B
(356 residues)
|
|
|
|
|
|
Crystal structure of usp7 in complex with a potent, selective and reversible small-molecule inhibitor
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: usp7, hausp. Expressed in: escherichia coli. Expression_system_taxid: 562
|
|
|
Chains:
A, B
(357 residues)
|
|
|
|
|
|
Sars-cov nsp10/nsp14 dynamic complex
|
|
|
Source: Sars coronavirus frankfurt 1. Organism_taxid: 229992. Expressed in: escherichia coli bl21(de3). Expression_system_taxid: 469008.
|
|
|
Chains:
A, B, C, D, M, N, O, P
(512 residues)
|
|
|
|
|
|
Crystal structure of usp7 in complex with the non-covalent inhibitor, ft671
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: usp7, hausp. Expressed in: escherichia coli. Expression_system_taxid: 562
|
|
|
Chains:
A, B
(337 residues)
|
|
|
|
|
|
Crystal structure of usp7 in complex with the covalent inhibitor, ft827
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: usp7, hausp. Expressed in: escherichia coli. Expression_system_taxid: 562
|
|
|
Chains:
A, B
(332 residues)
|
|
|
|
|
|
Structure of human coronavirus nl63 main protease in complex with the alpha-ketoamide tert-butyl ((s)-4-(benzylamino)-3,4-dioxo-1-((s)-2- oxopyrrolidin-3-yl)b- utan-2-yl)carbamate (tert-butyl -glnlactam-co- co-nh-benzyl)
|
|
|
Source: Human coronavirus nl63. Hcov-nl63. Organism_taxid: 277944. Gene: rep, 1a-1b. Expressed in: escherichia coli. Expression_system_taxid: 562
|
|
|
Chains:
A, B, C
(299 residues)
|
|
|
|
|
|
Crystal structure of human usp25
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: usp25, usp21. Expressed in: escherichia coli. Expression_system_taxid: 562
|
|
|
Chain:
A
(474 residues)
|
|
|
|
|
|
Structure of otulin bound to the met1-linked diubiquitin activity probe
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: otulin, fam105b. Expressed in: escherichia coli. Expression_system_taxid: 562. Synthetic: yes. Organism_taxid: 9606
|
|
|
Chain:
A
(266 residues)
|
|
|
|
|
|
Crystal structure of usp30 in covalent complex with ubiquitin propargylamide (high resolution)
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: usp30. Expressed in: escherichia coli bl21(de3), escherichia coli. Expression_system_taxid: 469008, 562. Expression_system_variant: rosetta 2 placi. Gene: ubb. Expressed in: escherichia coli.
|
|
|
Chain:
A
(304 residues)
|
|
|
|
|
|
Crystal structure of usp30 in covalent complex with ubiquitin propargylamide (low resolution)
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: usp30. Expressed in: escherichia coli bl21(de3). Expression_system_taxid: 469008. Expression_system_variant: rosetta 2 placi. Gene: ubb.
|
|
|
Chains:
A, C
(299 residues)
|
|
|
|
|
|
Crystal structure of usp30 (c77a) in complex with lys6-linked diubiquitin
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: usp30. Expressed in: escherichia coli bl21(de3). Expression_system_taxid: 469008. Expression_system_variant: rosetta 2 placi. Gene: ubb.
|
|
|
Chain:
A
(315 residues)
|
|
|
|
|
|
Ubiquitin specific protease 11 usp11 - peptide f complex
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: usp11, hcg_17279. Expressed in: escherichia coli. Expression_system_taxid: 562. Synthetic: yes. Synthetic construct. Organism_taxid: 32630
|
|
|
Chains:
A, B
(219 residues)
|
|
|
|
|
|
Covalent fragment group deposition -- crystal structure of outb2 in complex with p11
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: otub2, c14orf137, otb2, otu2. Expressed in: escherichia coli. Expression_system_taxid: 562
|
|
|
Chain:
A
(225 residues)
|
|
|
|
|
|
Covalent fragment group deposition -- crystal structure of outb2 in complex with pcm-0102153
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: otub2, c14orf137, otb2, otu2. Expressed in: escherichia coli. Expression_system_taxid: 562
|
|
|
Chain:
A
(223 residues)
|
|
|
|
|
|
Covalent fragment group deposition -- crystal structure of outb2 in complex with pcm-0103050
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: otub2, c14orf137, otb2, otu2. Expressed in: escherichia coli. Expression_system_taxid: 562
|
|
|
Chain:
A
(225 residues)
|
|
|
|
|
|
Covalent fragment group deposition -- crystal structure of outb2 in complex with pcm-0102305
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: otub2, c14orf137, otb2, otu2. Expressed in: escherichia coli. Expression_system_taxid: 562
|
|
|
Chain:
A
(225 residues)
|
|
|
|
|
|
Covalent fragment group deposition -- crystal structure of outb2 in complex with pcm-0102500
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: otub2, c14orf137, otb2, otu2. Expressed in: escherichia coli. Expression_system_taxid: 562
|
|
|
Chain:
A
(225 residues)
|
|
|
|
|
|
Covalent fragment group deposition -- crystal structure of outb2 in complex with pcm-0102821
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: otub2, c14orf137, otb2, otu2. Expressed in: escherichia coli. Expression_system_taxid: 562
|
|
|
Chain:
A
(225 residues)
|
|
|
|
|
|
Covalent fragment group deposition -- crystal structure of outb2 in complex with pcm-0103011
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: otub2, c14orf137, otb2, otu2. Expressed in: escherichia coli. Expression_system_taxid: 562
|
|
|
Chain:
A
(225 residues)
|
|
|
|
|
|
Covalent fragment group deposition -- crystal structure of outb2 in complex with pcm-0102998
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: otub2, c14orf137, otb2, otu2. Expressed in: escherichia coli. Expression_system_taxid: 562
|
|
|
Chain:
A
(225 residues)
|
|
|
|
|
|
Covalent fragment group deposition -- crystal structure of outb2 in complex with pcm-0102660
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: otub2, c14orf137, otb2, otu2. Expressed in: escherichia coli. Expression_system_taxid: 562
|
|
|
Chain:
A
(225 residues)
|
|
|
|
|
|
Covalent fragment group deposition -- crystal structure of outb2 in complex with pcm-0103007
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: otub2, c14orf137, otb2, otu2. Expressed in: escherichia coli. Expression_system_taxid: 562
|
|
|
Chain:
A
(223 residues)
|
|
|
|
|
|
Covalent fragment group deposition -- crystal structure of outb2 in complex with pcm-0102954
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: otub2, c14orf137, otb2, otu2. Expressed in: escherichia coli. Expression_system_taxid: 562
|
|
|
Chain:
A
(225 residues)
|
|
|
|
|
|
Covalent fragment group deposition -- crystal structure of outb2 in complex with pcm-0103080
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: otub2, c14orf137, otb2, otu2. Expressed in: escherichia coli. Expression_system_taxid: 562
|
|
|
Chain:
A
(225 residues)
|
|
|
|
|
|
Crystal structure of sars-cov papain-like protease in complex with thE C-terminal domain of human isg15
|
|
|
Source: Human sars coronavirus. Sars-cov. Organism_taxid: 227859. Gene: rep, 1a-1b. Expressed in: escherichia coli bl21(de3). Expression_system_taxid: 469008. Homo sapiens. Human. Organism_taxid: 9606.
|
|
|
Chains:
B, D
(315 residues)
|
|
|
|
|
|
Crystal structure of sars-cov papain-like protease in complex with c- terminal domain mouse isg15
|
|
|
Source: Mus musculus. Mouse. Organism_taxid: 10090. Gene: isg15, g1p2, ucrp. Expressed in: escherichia coli bl21(de3). Expression_system_taxid: 469008. Sars coronavirus. Sars-cov. Organism_taxid: 227859.
|
|
|
Chains:
B, D
(316 residues)
|
|
|
|
|
|
Crystal structure of usp35 c450s in complex with ubiquitin
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: usp35, kiaa1372, usp34. Expressed in: escherichia coli. Expression_system_taxid: 562. Gene: ubb. Expression_system_taxid: 562
|
|
|
Chain:
A
(317 residues)
|
|
|
|
|
|
Protein-protein complex between 26s proteasome regulatory subunit rpn8, rpn11, and ubiquitin s31
|
|
|
Source: Saccharomyces cerevisiae (strain atcc 204508 / s288c). Baker's yeast. Organism_taxid: 559292. Strain: atcc 204508 / s288c. Gene: rpn8, yor261c, o5360. Expressed in: escherichia coli. Expression_system_taxid: 562. Gene: rpn11, mpr1, yfr004w.
|
|
|
Chain:
B
(159 residues)
|
|
|
|
|
|
Usp7 in complex with gne6640 (4-(2-amino-4-ethyl-5-(1h-indazol-5-yl) pyridin-3-yl)phenol)
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: usp7, hausp. Expressed in: escherichia coli. Expression_system_taxid: 469008.
|
|
|
Chains:
A, B
(329 residues)
|
|
|
|
|
|
Usp7 in complex with gne6776 (6'-amino-4'-ethyl-5'-(4-hydroxyphenyl)- n-methyl-[3,3'-bipyridine]-6-carboxamide)
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: usp7, hausp. Expressed in: escherichia coli. Expression_system_taxid: 469008.
|
|
|
Chains:
A, B
(346 residues)
|
|
|
|
|
|
Sars-unique fold in the rousettus bat coronavirus hku9
|
|
|
Source: Rousettus bat coronavirus hku9. Btcov. Organism_taxid: 694006. Gene: rep, 1a-1b. Expressed in: escherichia coli. Expression_system_taxid: 469008.
|
|
|
Chain:
A
(77 residues)
|
|
|
|
|
|
Human a20 otu domain (wt) with acetamidylated c103
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: tnfaip3, otud7c. Expressed in: escherichia coli. Expression_system_taxid: 469008.
|
|
|
Chains:
A, B, C, D, E, F
(312 residues)
|
|
|
|
|
|
Human a20 otu domain (i325n) with acetamidylated c103
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: tnfaip3, otud7c. Expressed in: escherichia coli. Expression_system_taxid: 469008.
|
|
|
Chains:
A, B, C, D, E, F
(316 residues)
|
|
|
|
|
|
Otu protease of crimean congo hemorrhagic fever virus bound to ubiquitin variant cc.4
|
|
|
Source: Crimean-congo hemorrhagic fever virus (strain nigeria/ibar10200/1970). Cchfv. Organism_taxid: 652961. Strain: nigeria/ibar10200/1970. Expressed in: escherichia coli bl21(de3). Expression_system_taxid: 469008. Synthetic construct. Organism_taxid: 32630.
|
|
|
Chains:
A, C
(165 residues)
|
|
|
|
|
|
Otu protease of crimean congo hemorrhagic fever virus bound to ubiquitin variant cc.2
|
|
|
Source: Crimean-congo hemorrhagic fever virus (strain nigeria/ibar10200/1970). Cchfv. Organism_taxid: 652961. Strain: nigeria/ibar10200/1970. Expressed in: escherichia coli bl21(de3). Expression_system_taxid: 469008. Synthetic construct. Organism_taxid: 32630.
|
|
|
Chain:
A
(163 residues)
|
|
|
|
|
|
Otu protease of crimean congo hemorrhagic fever virus bound to ubiquitin variant cc.1
|
|
|
Source: Crimean-congo hemorrhagic fever virus (strain nigeria/ibar10200/1970). Cchfv. Organism_taxid: 652961. Strain: nigeria/ibar10200/1970. Expressed in: escherichia coli bl21. Expression_system_taxid: 511693. Synthetic construct. Organism_taxid: 32630.
|
|
|
Chains:
A, C
(162 residues)
|
|
|
|
|
|
Crystal structure of the middle east respiratory syndrome coronavirus papain-like protease bound to ubiquitin variant me.4
|
|
|
Source: Human betacoronavirus 2c emc/2012. Organism_taxid: 1235996. Gene: orf1ab. Expressed in: escherichia coli bl21(de3). Expression_system_taxid: 469008. Homo sapiens. Organism_taxid: 9606. Expression_system_taxid: 469008
|
|
|
Chain:
A
(322 residues)
|
|
|
|
|
|
Crystal structure of the middle east respiratory syndrome coronavirus papain-like protease bound to ubiquitin variant me.2
|
|
|
Source: Human betacoronavirus 2c emc/2012. Organism_taxid: 1235996. Gene: orf1ab. Expressed in: escherichia coli bl21(de3). Expression_system_taxid: 469008. Homo sapiens. Organism_taxid: 9606. Expression_system_taxid: 469008
|
|
|
Chain:
A
(320 residues)
|
|
|
|
|
|
Crystal structure of a putative ubl domain of usp9x
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: usp9x, hcg_18381. Expressed in: escherichia coli. Expression_system_taxid: 469008.
|
|
|
Chain:
A
(85 residues)
|
|
|
|
|
|
Structure of dub complex
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: usp7, hausp. Expressed in: escherichia coli. Expression_system_taxid: 469008.
|
|
|
Chains:
A, B
(339 residues)
|
|
|
|
|
|
Structure of dub complex
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: usp7, hausp. Expressed in: escherichia coli. Expression_system_taxid: 469008.
|
|
|
Chains:
A, B
(335 residues)
|
|
|
|
|
|
Structure of dub complex
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: usp7, hausp. Expressed in: escherichia coli. Expression_system_taxid: 469008.
|
|
|
Chains:
A, B
(330 residues)
|
|
|
|
|
|
Rpn8/rpn11 dimer complex
|
|
|
Source: Saccharomyces cerevisiae (strain atcc 204508 / s288c). Baker's yeast. Organism_taxid: 559292. Strain: atcc 204508 / s288c. Gene: rpn8, yor261c, o5360. Expressed in: escherichia coli. Expression_system_taxid: 562. Gene: rpn11, mpr1, yfr004w.
|
|
|
Chain:
B
(158 residues)
|
|
|
|
|
|
Crystal structure of mers-cov papain-like protease in complex with thE C-terminal domain of human isg15
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: isg15, g1p2, ucrp. Expressed in: escherichia coli. Expression_system_taxid: 562. Human betacoronavirus 2c emc/2012. Organism_taxid: 1235996. Gene: orf1ab.
|
|
|
Chains:
A, C
(319 residues)
|
|
|
|
|
|
Crystal structure of mers-cov papain-like protease in complex with thE C-terminal domain of human isg15
|
|
|
Source: Human betacoronavirus 2c emc/2012. Organism_taxid: 1235996. Gene: orf1ab. Expressed in: escherichia coli. Expression_system_taxid: 562. Homo sapiens. Human. Organism_taxid: 9606. Gene: isg15, g1p2, ucrp.
|
|
|
Chains:
A, C
(319 residues)
|
|
|
|
|
|
Crystal structure of the catalytic domain of human usp9x
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: usp9x, dffrx, fam, usp9. Expressed in: escherichia coli. Expression_system_taxid: 511693.
|
|
|
Chains:
A, B, C, D
(350 residues)
|
|
|
|
|
|
X-ray structure of mhv plp2 (cys1716ser) catalytic mutant in complex with free ubiquitin
|
|
|
Source: Murine coronavirus (strain a59). Mhv-a59. Organism_taxid: 11142. Strain: a59. Gene: rep, 1a-1b. Expressed in: escherichia coli. Expression_system_taxid: 562. Homo sapiens. Human.
|
|
|
Chains:
A, B
(301 residues)
|
|
|
|
|
|
Usp7 in complex with cpd2 (4-(3-(1-methylpiperidin-4-yl)-1,2,4- oxadiazol-5-yl)phenol)
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: usp7, hausp. Expressed in: escherichia coli. Expression_system_taxid: 469008.
|
|
|
Chains:
A, B
(338 residues)
|
|
|
|
|
|
2.05 a resolution structure of mers 3cl protease in complex with inhibitor gc376
|
|
|
Source: Middle east respiratory syndrome-related coronavirus. Organism_taxid: 1335626. Gene: orf1a. Expressed in: escherichia coli. Expression_system_taxid: 511693.
|
|
|
Chain:
A
(302 residues)
|
|
|
|
|
|
1.55 a resolution structure of mers 3cl protease in complex with inhibitor gc813
|
|
|
Source: Middle east respiratory syndrome-related coronavirus. Organism_taxid: 1335626. Gene: orf1a. Expressed in: escherichia coli. Expression_system_taxid: 511693.
|
|
|
Chain:
A
(301 residues)
|
|
|
|
|
|
1.85 a resolution structure of mers 3cl protease in complex with piperidine-based peptidomimetic inhibitor 17
|
|
|
Source: Middle east respiratory syndrome-related coronavirus. Organism_taxid: 1335626. Gene: orf1a. Expressed in: escherichia coli. Expression_system_taxid: 511693.
|
|
|
Chain:
A
(303 residues)
|
|
|
|
|
|
2.25 a resolution structure of mers 3cl protease in complex with piperidine-based peptidomimetic inhibitor 21
|
|
|
Source: Middle east respiratory syndrome-related coronavirus. Organism_taxid: 1335626. Gene: orf1a. Expressed in: escherichia coli. Expression_system_taxid: 511693.
|
|
|
Chain:
A
(301 residues)
|
|
|
|
|
|
Crystal structure of middle east respiratory syndrome coronavirus helicase (mers-cov nsp13)
|
|
|
Source: Human betacoronavirus 2c emc/2012. Organism_taxid: 1235996. Gene: orf1ab. Expressed in: trichoplusia ni. Expression_system_taxid: 7111.
|
|
|
Chains:
B, A
(591 residues)
|
|
|
|
|
|
Crystal structure basis for pedv nsp1
|
|
|
Source: Porcine epidemic diarrhea virus. Organism_taxid: 28295. Expressed in: escherichia coli bl21. Expression_system_taxid: 511693.
|
|
|
Chains:
A, B
(117 residues)
|
|
|
|
|
|
Crystal structure of human usp2 in complex with ubiquitin and 6- thioguanine
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: usp2, ubp41. Expressed in: escherichia coli. Expression_system_taxid: 562. Bos taurus. Bovine. Organism_taxid: 9913
|
|
|
Chain:
A
(327 residues)
|
|
|
|
|
|
Crystal structure of human usp2 c276s mutant in complex with ubiquitin
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: usp2, ubp41. Expressed in: escherichia coli. Expression_system_taxid: 562. Bos taurus. Bovine. Organism_taxid: 9913
|
|
|
Chain:
A
(331 residues)
|
|
|
|
|
|
Crystal structure of sars coronavirus papain-like protease in complex with glycerol
|
|
|
Source: Human sars coronavirus. Sars-cov. Organism_taxid: 227859. Gene: 1a. Expressed in: escherichia coli. Expression_system_taxid: 562
|
|
|
Chain:
A
(317 residues)
|
|
|
|
|
|
Crystal structure of sars coronavirus papain-like protease conjugated with beta-mercaptoethanol
|
|
|
Source: Human sars coronavirus. Sars-cov. Organism_taxid: 227859. Gene: 1a. Expressed in: escherichia coli. Expression_system_taxid: 562
|
|
|
Chain:
A
(317 residues)
|
|
|
|
|
|
Prrsv nsp4
|
|
|
Source: Porcine reproductive and respiratory syndrome virus. Prrsv. Organism_taxid: 28344. Gene: orf1a. Expressed in: escherichia coli bl21(de3). Expression_system_taxid: 469008.
|
|
|
Chains:
B, A, C, D
(203 residues)
|
|
|
|
|
|
Crystal structure of porcine delta coronavirus nsp9
|
|
|
Source: Porcine coronavirus hku15. Organism_taxid: 1159905. Gene: orf1ab. Expressed in: escherichia coli bl21(de3). Expression_system_taxid: 469008.
|
|
|
Chains:
A, B, C, D
(97 residues)
|
|
|
|
|
|
Crystal structure of porcine delta coronavirus nsp9-n7
|
|
|
Source: Porcine coronavirus hku15. Organism_taxid: 1159905. Gene: orf1ab. Expressed in: escherichia coli bl21(de3). Expression_system_taxid: 469008.
|
|
|
Chains:
A, B
(90 residues)
|
|
|
|
|
|
Crystal structure of mers-cov nsp10/nsp16 complex
|
|
|
Source: Human betacoronavirus 2c emc/2012. Organism_taxid: 1235996. Gene: orf1ab. Expressed in: escherichia coli bl21(de3). Expression_system_taxid: 469008.
|
|
|
Chains:
A, B
(289 residues)
|
|
|
|
|
|
Crystal structure of mers-cov nsp10/nsp16 complex bound to sam
|
|
|
Source: Human betacoronavirus 2c emc/2012. Organism_taxid: 1235996. Gene: orf1ab. Expressed in: escherichia coli bl21(de3). Expression_system_taxid: 469008.
|
|
|
Chains:
A, B
(283 residues)
|
|
|
|
Bound ligand:
|
Het Group SAM
is 50.00% similar to
enzyme product ADP
|
|
|
|
|
|
|
Crystal structure of mers-cov nsp16/nsp10 complex bound to sah
|
|
|
Source: Human betacoronavirus 2c emc/2012. Organism_taxid: 1235996. Gene: orf1ab. Expressed in: escherichia coli bl21(de3). Expression_system_taxid: 469008.
|
|
|
Chains:
A, B
(281 residues)
|
|
|
|
Bound ligand:
|
Het Group SAH
is 51.43% similar to
enzyme product ADP
|
|
|
|
|
|
|
Crystal structure of mers-cov nsp16/nsp10 complex bound to sinefungin
|
|
|
Source: Human betacoronavirus 2c emc/2012. Organism_taxid: 1235996. Gene: orf1ab. Expressed in: escherichia coli bl21(de3). Expression_system_taxid: 469008.
|
|
|
Chains:
A, B
(291 residues)
|
|
|
|
Bound ligand:
|
Het Group SFG
is 50.00% similar to
enzyme product ADP
|
|
|
|
|
|
|
Crystal structure of mers-cov nsp16/nsp10 complex bound to m7gpppa
|
|
|
Source: Human betacoronavirus 2c emc/2012. Organism_taxid: 1235996. Gene: orf1ab. Expressed in: escherichia coli bl21(de3). Expression_system_taxid: 469008.
|
|
|
Chains:
A, B
(293 residues)
|
|
|
|
Bound ligand:
|
Het Group GTA
is 60.78% similar to
enzyme reactant ATP
|
|
|
|
|
|
|
Crystal structure of mers-cov nsp16/nsp10 complex bound to sam and m7gpppg
|
|
|
Source: Human betacoronavirus 2c emc/2012. Organism_taxid: 1235996. Gene: orf1ab. Expressed in: escherichia coli bl21(de3). Expression_system_taxid: 469008.
|
|
|
Chains:
A, B
(294 residues)
|
|
|
|
Bound ligand:
|
Het Group GTG
is 59.62% similar to
enzyme reactant ATP
|
|
|
|
|
|
|
Crystal structure of mers-cov nsp16/nsp10 complex bound to m7gpppg
|
|
|
Source: Human betacoronavirus 2c emc/2012. Organism_taxid: 1235996. Gene: orf1ab. Expressed in: escherichia coli bl21(de3). Expression_system_taxid: 469008.
|
|
|
Chains:
A, B
(293 residues)
|
|
|
|
Bound ligand:
|
Het Group GTG
is 59.62% similar to
enzyme reactant ATP
|
|
|
|
|
|
|
Crystal structure of mers-cov nsp16/nsp10 complex bound to sam and m7gpppa
|
|
|
Source: Human betacoronavirus 2c emc/2012. Organism_taxid: 1235996. Gene: orf1ab. Expressed in: escherichia coli bl21(de3). Expression_system_taxid: 469008.
|
|
|
Chains:
A, B
(290 residues)
|
|
|
|
Bound ligand:
|
Het Group GTA
is 60.78% similar to
enzyme reactant ATP
|
|
|
|
|
|
|
Crystal structure of mers-cov nsp16/nsp10complex bound to sinefungin and m7gpppg
|
|
|
Source: Human betacoronavirus 2c emc/2012. Organism_taxid: 1235996. Gene: orf1ab. Expressed in: escherichia coli bl21(de3). Expression_system_taxid: 469008.
|
|
|
Chains:
A, B
(295 residues)
|
|
|
|
Bound ligand:
|
Het Group GTG
is 59.62% similar to
enzyme reactant ATP
|
|
|
|
|
|
|
Crystal structure of mers-cov nsp16/nsp10 complex bound to sah and m7gpppa
|
|
|
Source: Human betacoronavirus 2c emc/2012. Organism_taxid: 1235996. Gene: orf1ab. Expressed in: escherichia coli bl21(de3). Expression_system_taxid: 469008.
|
|
|
Chains:
A, B
(291 residues)
|
|
|
|
Bound ligand:
|
Het Group GTA
is 60.78% similar to
enzyme reactant ATP
|
|
|
|
|
|
|
Crystal structure of mers-cov nsp16/nsp10 complex bound to sinefungin and m7gpppa
|
|
|
Source: Human betacoronavirus 2c emc/2012. Organism_taxid: 1235996. Gene: orf1ab. Expressed in: escherichia coli bl21(de3). Expression_system_taxid: 469008.
|
|
|
Chains:
A, B
(294 residues)
|
|
|
|
Bound ligand:
|
Het Group GTA
is 60.78% similar to
enzyme reactant ATP
|
|
|
|
|
|
|
Crystal structure of mers-cov nsp16/nsp10 complex bound to sah and m7gpppg
|
|
|
Source: Human betacoronavirus 2c emc/2012. Organism_taxid: 1235996. Gene: orf1ab. Expressed in: escherichia coli bl21(de3). Expression_system_taxid: 469008.
|
|
|
Chains:
A, B
(291 residues)
|
|
|
|
Bound ligand:
|
Het Group GTG
is 59.62% similar to
enzyme reactant ATP
|
|
|
|
|
|
|
Structural and biochemical characterization of endoribonuclease nsp15 encoded by middle east respiratory syndrome coronavirus
|
|
|
Source: Middle east respiratory syndrome-related coronavirus. Organism_taxid: 1335626. Expressed in: escherichia coli. Expression_system_taxid: 562
|
|
|
Chains:
A, B
(341 residues)
|
|
|
|
|
|
Complex structure of pedv 3clpro mutant (c144a) with nemo-231 peptite substrate
|
|
|
Source: Porcine epidemic diarrhea virus. Organism_taxid: 28295. Expressed in: escherichia coli bl21(de3). Expression_system_taxid: 469008. Synthetic: yes. Sus scrofa. Organism_taxid: 9823
|
|
|
Chains:
A, B
(292 residues)
|
|
|
|
|
|
Crystal structure of mers-cov macro domain in complex with amp
|
|
|
Source: Middle east respiratory syndrome-related coronavirus. Organism_taxid: 1335626. Expressed in: escherichia coli bl21(de3). Expression_system_taxid: 469008
|
|
|
Chain:
A
(165 residues)
|
|
|
|
|
|
Crystal structure of mers-cov macro domain in complex with adp
|
|
|
Source: Middle east respiratory syndrome-related coronavirus. Organism_taxid: 1335626. Expressed in: escherichia coli bl21(de3). Expression_system_taxid: 469008
|
|
|
Chain:
A
(165 residues)
|
|
|
|
|
|
Crystal structure of mers-cov macro domain in complex with atp
|
|
|
Source: Middle east respiratory syndrome-related coronavirus. Organism_taxid: 1335626. Expressed in: escherichia coli bl21(de3). Expression_system_taxid: 469008
|
|
|
Chain:
A
(166 residues)
|
|
|
|
|
|
Crystal structure of mers-cov macro domain in complex with NAD
|
|
|
Source: Middle east respiratory syndrome-related coronavirus. Organism_taxid: 1335626. Expressed in: escherichia coli bl21(de3). Expression_system_taxid: 469008
|
|
|
Chain:
A
(165 residues)
|
|
|
|
|
|
Anthrax toxin receptor 1-bound spent particles of seneca valley virus in acidic conditions
|
|
|
Source: Senecavirus a. Organism_taxid: 390157. Homo sapiens. Human. Organism_taxid: 9606. Gene: antxr1. Expressed in: enterobacteria phage l1. Expression_system_taxid: 268588
|
|
|
Chain:
B
(246 residues)
|
|
|
|
|
|
The cryo-em structure of the precusor of human pre-catalytic spliceosome (pre-b complex)
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Synthetic: yes. Organism_taxid: 9606
|
|
|
Chain:
W
(463 residues)
|
|
|
|
Bound ligand:
|
Het Group GTP
is 96.88% similar to
enzyme reactant ATP
|
|
|
|
|
|
|
Saga dub module ubp8(c146a)/sgf11/sus1/sgf73 bound to monoubiquitin
|
|
|
Source: Saccharomyces cerevisiae s288c. Baker's yeast. Organism_taxid: 559292. Strain: atcc 204508 / s288c. Gene: ubp8, ymr223w, ym9959.05. Expressed in: escherichia coli. Expression_system_taxid: 562. Gene: sus1, ybr111w-a. Gene: sgf11, ypl047w.
|
|
|
Chain:
A
(442 residues)
|
|
|
|
|
|
X-ray structure of mers coronavirus papain-like protease in complex with human isg15
|
|
|
Source: Human betacoronavirus 2c emc/2012. Organism_taxid: 1235996. Gene: orf1ab. Expressed in: escherichia coli bl21(de3). Expression_system_taxid: 469008. Homo sapiens. Human. Organism_taxid: 9606. Gene: isg15, g1p2, ucrp.
|
|
|
Chains:
A, B
(259 residues)
|
|
|
|
|
|
Structure of the pr-dub complex
|
|
|
Source: Drosophila melanogaster. Fruit fly. Organism_taxid: 7227. Gene: calypso, cg8445. Expressed in: escherichia coli. Expression_system_taxid: 562. Gene: asx, cg8787. Expression_system_taxid: 562
|
|
|
Chains:
A, C
(293 residues)
|
|
|
|
|
|
Structure of the usp15 deubiquitinase domain in complex with a third- generation inhibitory ubv
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: usp15, kiaa0529. Expressed in: escherichia coli. Expression_system_taxid: 562.
|
|
|
Chains:
C, D
(339 residues)
|
|
|
|
|
|
Structure of the usp15 deubiquitinase domain in complex with a high- affinity first-generation ubv
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: usp15, kiaa0529. Expressed in: escherichia coli. Expression_system_taxid: 562. Gene: ubb.
|
|
|
Chains:
A, B, C, D
(343 residues)
|
|
|
|
|
|
Cryo-em structure of seneca valley virus-anthrax toxin receptor 1 complex
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: antxr1, atr, tem8. Expressed in: homo sapiens. Expression_system_taxid: 9606. Senecavirus a. Organism_taxid: 390157. Organism_taxid: 390157
|
|
|
Chains:
A, C, B, D
(258 residues)
|
|
|
|
|
|
Ubiquitin variant bound to usp2
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: usp2, ubp41. Expressed in: escherichia coli. Expression_system_taxid: 562. Gene: ubb. Expression_system_taxid: 562
|
|
|
Chain:
A
(330 residues)
|
|
|
|
|
|
Structure of the usp15 dusp domain in complex with a high-affinity ubiquitin variant (ubv)
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: usp15, kiaa0529. Expressed in: escherichia coli. Expression_system_taxid: 562.
|
|
|
Chains:
A, B, C, D, E, F
(131 residues)
|
|
|
|
|
|
Crystal structure of the viral otu domain protease from taggert virus
|
|
|
Source: Taggert virus. Organism_taxid: 487050. Expressed in: escherichia coli. Expression_system_taxid: 562
|
|
|
Chains:
A, B, C, D
(161 residues)
|
|
|
|
|
|
Structure of usp5 zinc-finger ubiquitin binding domain co-crystallized with 4-(4-tert-butylphenyl)-4-oxobutanoate
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: usp5, isot. Expressed in: escherichia coli. Expression_system_taxid: 562.
|
|
|
Chain:
A
(117 residues)
|
|
|
|
|
|
Structure of usp5 zinc-finger ubiquitin binding domain co-crystallized with 3-(5-phenyl-1,3,4-oxadiazol-2-yl)propanoate
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: usp5, isot. Expressed in: escherichia coli. Expression_system_taxid: 562.
|
|
|
Chains:
A, B
(112 residues)
|
|
|
|
|
|
Yeast 26s proteasome bound to ubiquitinated substrate (4d motor state)
|
|
|
Source: Saccharomyces cerevisiae s288c. Baker's yeast. Organism_taxid: 559292. Strain: atcc 204508 / s288c. Gene: pre3, yjl001w, j1407. Expressed in: saccharomyces cerevisiae w303. Expression_system_taxid: 580240. Gene: pup1, yor157c. Gene: pup3, yer094c.
|
|
|
Chain:
r
(280 residues)
|
|
|
|
|
|
Crystal structure of the covalent complex between deubiquitinase zufsp (zup1) and ubiquitin-pa
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: zufsp, c6orf113. Expressed in: escherichia coli bl21(de3). Expression_system_taxid: 469008. Expression_system_variant: rosetta plyss. Gene: ubb. Expression_system_variant: rosetta plyss
|
|
|
Chain:
A
(335 residues)
|
|
|
|
|
|
Crystal structure of usp7 in complex with a 4-hydroxypiperidine based inhibitor
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: usp7, hausp. Expressed in: escherichia coli. Expression_system_taxid: 562
|
|
|
Chains:
A, B
(350 residues)
|
|
|
|
|
|
Crystal structure of human zufsp/zup1 in complex with ubiquitin
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: zufsp, c6orf113. Expressed in: escherichia coli bl21(de3). Expression_system_taxid: 469008. Gene: ubb. Expression_system_taxid: 469008
|
|
|
Chain:
A
(343 residues)
|
|
|
|
|
|
Caldiarchaeum subterraneum ubiquitin:rpn11-homolog complex
|
|
|
Source: Candidatus caldiarchaeum subterraneum. Organism_taxid: 311458. Gene: csub_c1473, hgmm_f04b03c04, hgmm_f21d07c20, hgmm_f30c12c32. Expressed in: escherichia coli. Expression_system_taxid: 562. Gene: csub_c1474, hgmm_f04b03c03, hgmm_f21d07c21, hgmm_f30c12c33. Expression_system_taxid: 562
|
|
|
Chains:
A, B
(149 residues)
|
|
|
|
|
|
Structure of human coronavirus nl63 main protease in complex with the alpha-ketoamide (s)-n-((s)-4-(benzylamino)-3,4-dioxo-1-((s)-2- oxopyrrolidin-3-yl)butan-2-yl)-2-cinnamamido-4-methylpentanamide (cinnamoyl-leucine-glnlactam-co-co-nh-benzyl)
|
|
|
Source: Human coronavirus nl63. Hcov-nl63. Organism_taxid: 277944. Gene: rep, 1a-1b. Expressed in: escherichia coli. Expression_system_taxid: 562
|
|
|
Chains:
A, B, C
(300 residues)
|
|
|
|
|
|
Structure of human coronavirus nl63 main protease in complex with the alpha-ketoamide (s)-n-benzyl-3-((s)-2-cinnamamido-3- phenylpropanamido)-2-oxo-4-((s)-2-oxopyrrolidin-3-yl)butanamide (cinnamoyl-phenylalanine-glnlactam-co-co-nh-benzyl)
|
|
|
Source: Human coronavirus nl63. Hcov-nl63. Organism_taxid: 277944. Gene: rep, 1a-1b. Expressed in: escherichia coli. Expression_system_taxid: 562
|
|
|
Chains:
A, B, C
(301 residues)
|
|
|
|
|
|
Usp15 catalytic domain in complex with small molecule
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: usp15, kiaa0529. Expressed in: escherichia coli. Expression_system_taxid: 562
|
|
|
Chains:
A, B
(331 residues)
|
|
|
|
|
|
Usp15 catalytic domain structure
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: usp15, kiaa0529. Expressed in: escherichia coli. Expression_system_taxid: 562
|
|
|
Chain:
A
(325 residues)
|
|
|
|
|
|
Usp28 catalytic domain variant e593d in complex with ubpa
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: usp28, kiaa1515. Expressed in: escherichia coli bl21(de3). Expression_system_taxid: 469008. Gene: ubb. Expression_system_taxid: 469008
|
|
|
Chains:
A, B
(458 residues)
|
|
|
|
|
|
Usp28 catalytic domain apo
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: usp28, kiaa1515. Expressed in: escherichia coli bl21(de3). Expression_system_taxid: 469008
|
|
|
Chains:
A, C
(456 residues)
|
|
|
|
|
|
Usp25 catalytic domain
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: usp25, usp21. Expressed in: escherichia coli bl21(de3). Expression_system_taxid: 469008
|
|
|
Chains:
A, B
(488 residues)
|
|
|
|
|
|
Structure of the usp25 c-terminal domain
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: usp25, usp21. Expressed in: escherichia coli bl21(de3). Expression_system_taxid: 469008
|
|
|
Chain:
A
(270 residues)
|
|
|
|
|
|
Structure of the catalytic domain of usp28 (insertion deleted)
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: usp28, kiaa1515. Expressed in: escherichia coli bl21(de3). Expression_system_taxid: 469008. Expression_system_variant: rosetta2 placi
|
|
|
Chain:
A
(339 residues)
|
|
|
|
|
|
Structure of the catalytic domain of usp28 (insertion deleted) bound to ubiquitin-pa
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: usp28, kiaa1515. Expressed in: escherichia coli bl21(de3). Expression_system_taxid: 469008. Expression_system_variant: rosetta2 placi. Gene: ubb. Expressed in: escherichia coli.
|
|
|
Chain:
A
(346 residues)
|
|
|
|
|
|
Structure of human usp28
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: usp28, kiaa1515. Expressed in: escherichia coli bl21(de3). Expression_system_taxid: 469008. Expression_system_variant: rosetta2 placi
|
|
|
Chains:
A, B
(436 residues)
|
|
|
|
|
|
Structure of human usp28 bound to ubiquitin-pa
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: usp28, kiaa1515. Expressed in: escherichia coli bl21(de3). Expression_system_taxid: 469008. Expression_system_variant: rosetta2 placi. Gene: ubb. Expression_system_variant: rosetta2 placi
|
|
|
Chains:
A, C
(453 residues)
|
|
|
|
|
|
Structure of human usp25
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: usp25, usp21. Expressed in: escherichia coli bl21(de3). Expression_system_taxid: 469008. Expression_system_variant: rosetta2 placi
|
|
|
Chains:
A, B
(465 residues)
|
|
|
|
|
|
Structure of thE C-terminal domain of usp25 (748-1048)
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: usp25, usp21. Expressed in: escherichia coli bl21(de3). Expression_system_taxid: 469008. Expression_system_variant: rosetta2 placi
|
|
|
Chain:
A
(300 residues)
|
|
|
|
|
|
Structure of calypso in complex with deubad of asx
|
|
|
Source: Drosophila melanogaster. Fruit fly. Organism_taxid: 7227. Gene: calypso, cg8445. Expressed in: escherichia coli. Expression_system_taxid: 562. Gene: asx, cg8787. Expression_system_taxid: 562
|
|
|
Chains:
A, B
(304 residues)
|
|
|
|
|
|
Structure of the otu domain of otulin g281r mutant
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: otulin, fam105b. Expressed in: escherichia coli. Expression_system_taxid: 562
|
|
|
Chain:
A
(260 residues)
|
|
|
|
|
|
Usp14 catalytic domain with iu1
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: usp14, tgt. Expressed in: escherichia coli-pichia pastoris shuttle vector ppparg4. Expression_system_taxid: 1182032
|
|
|
Chains:
A, B
(335 residues)
|
|
|
|
|
|
Usp14 catalytic domain bind to iu1-47
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: usp14, tgt. Expressed in: escherichia coli bl21(de3). Expression_system_taxid: 469008.
|
|
|
Chains:
A, B
(341 residues)
|
|
|
|
|
|
Usp14 catalytic domain with iu1-206
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: usp14, tgt. Expressed in: escherichia coli bl21(de3). Expression_system_taxid: 469008.
|
|
|
Chains:
A, B
(338 residues)
|
|
|
|
|
|
Usp14 catalytic domain with iu1-248
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: usp14, tgt. Expressed in: escherichia coli bl21(de3). Expression_system_taxid: 469008.
|
|
|
Chains:
A, B
(336 residues)
|
|
|
|
|
|
Crystal structure of lys27-linked di-ubiquitin in complex with its selective interacting protein uchl3
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: uchl3. Expressed in: escherichia coli bl21(de3). Expression_system_taxid: 469008. Gene: ubb.
|
|
|
Chain:
A
(227 residues)
|
|
|
|
|
|
The full length of tgev nsp1
|
|
|
Source: Transmissible gastroenteritis virus. Organism_taxid: 11149. Expressed in: escherichia coli bl21. Expression_system_taxid: 511693.
|
|
|
Chains:
A, B, E, F
(105 residues)
|
|
|
|
|
|
Tgev nsp1 mutant - 91-95sg
|
|
|
Source: Transmissible gastroenteritis virus. Organism_taxid: 11149. Expressed in: escherichia coli bl21. Expression_system_taxid: 511693.
|
|
|
Chains:
A, B
(107 residues)
|
|
|
|
|
|
The crystal structure of main protease from mouse hepatitis virus a59 in complex with an inhibitor
|
|
|
Source: Murine coronavirus (strain a59). Mhv-a59. Organism_taxid: 11142. Strain: a59. Expressed in: escherichia coli. Expression_system_taxid: 562. Synthetic: yes. Synthetic construct. Organism_taxid: 32630
|
|
|
Chains:
B, C, A
(297 residues)
|
|
|
|
|
|
Crystal structure of human usp46-wdr48-wdr20 complex
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: usp46. Expressed in: escherichia coli. Expression_system_taxid: 562. Gene: wdr48. Expressed in: spodoptera frugiperda. Expression_system_taxid: 7108.
|
|
|
Chain:
A
(292 residues)
|
|
|
|
|
|
Delicate structural coordination of the severe acute respiratory syndrome coronavirus nsp13 upon atp hydrolysis
|
|
|
Source: Human sars coronavirus. Sars-cov. Organism_taxid: 694009. Gene: rep, 1a-1b. Expressed in: escherichia coli. Expression_system_taxid: 562
|
|
|
Chains:
A, B
(597 residues)
|
|
|
|
|
|
Solution structure of the cs1 domain of usp19
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: usp19, kiaa0891, zmynd9. Expressed in: eschenbachia. Expression_system_taxid: 1408200
|
|
|
Chain:
A
(92 residues)
|
|
|
|
|
|
Rice_otub_like_catalytic domain
|
|
|
Source: Oryza sativa subsp. Japonica. Rice. Organism_taxid: 39947. Gene: osj_28104. Expressed in: escherichia coli. Expression_system_taxid: 562
|
|
|
Chains:
A, B, C, D
(242 residues)
|
|
|
|
|
|
Structure of deubiquitinase
|
|
|
Source: Oryza sativa subsp. Japonica. Rice. Organism_taxid: 39947. Gene: osj_28104. Expressed in: escherichia coli. Expression_system_taxid: 562. Homo sapiens. Human. Organism_taxid: 9606.
|
|
|
Chain:
B
(241 residues)
|
|
|
|
|
|
Structure of deubiquitinase
|
|
|
Source: Oryza sativa subsp. Japonica. Rice. Organism_taxid: 39947. Gene: osj_28104. Expressed in: escherichia coli. Expression_system_taxid: 562. Homo sapiens. Human. Organism_taxid: 9606.
|
|
|
Chain:
B
(239 residues)
|
|
|
|
|
|
Solution structure of the znf-ubp domain of usp20/vdu2
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: usp20, kiaa1003, lsfr3a, vdu2. Expressed in: escherichia coli. Expression_system_taxid: 562
|
|
|
Chain:
A
(99 residues)
|
|
|
|
|
|
Solution structure of the cs2 domain of usp19
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: usp19, kiaa0891, zmynd9. Expressed in: escherichia coli. Expression_system_taxid: 562
|
|
|
Chain:
A
(114 residues)
|
|
|
|
|
|
Solution structure of the ubl domain of usp19
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: usp19, kiaa0891, zmynd9. Expressed in: escherichia coli. Expression_system_taxid: 562
|
|
|
Chain:
A
(88 residues)
|
|
|
|
|
|
Crystal structure of senecavirus a 3c protease
|
|
|
Source: Senecavirus a. Organism_taxid: 390157. Expressed in: escherichia coli. Expression_system_taxid: 562
|
|
|
Chains:
A, B
(206 residues)
|
|
|
|
|
|
The crystal structure of sads-cov papain like protease
|
|
|
Source: Swine acute diarrhea syndrome coronavirus. Organism_taxid: 2032731. Gene: orf1ab, orf1ab. Expressed in: escherichia coli bl21(de3). Expression_system_taxid: 469008.
|
|
|
Chain:
A
(234 residues)
|
|
|
|
|
|
Complex structure of pedv 3clpro with gc376
|
|
|
Source: Porcine epidemic diarrhea virus. Organism_taxid: 28295. Gene: pol1. Expressed in: escherichia coli k-12. Expression_system_taxid: 83333.
|
|
|
Chains:
A, B
(299 residues)
|
|
|
|
|
|
Crystal structure of three main domains of nonstructural protein 3 from coronavirus
|
|
|
Source: Porcine deltacoronavirus. Organism_taxid: 1586324. Gene: orf1ab. Expressed in: escherichia coli bl21. Expression_system_taxid: 511693
|
|
|
Chain:
A
(425 residues)
|
|
|
|
|
|
The co-crystal structure of sars-cov 3c like protease with aldehyde inhibitor m7
|
|
|
Source: Severe acute respiratory syndrome-related coronavirus. Sarsr-cov. Organism_taxid: 694009. Expressed in: escherichia coli. Expression_system_taxid: 562
|
|
|
Chain:
A
(306 residues)
|
|
|
|
|
|
The co-crystal structure of severe acute respiratory syndrome coronavirus 3c-like protease with aldehyde m15
|
|
|
Source: Human sars coronavirus. Sars-cov. Organism_taxid: 694009. Gene: 1a. Expressed in: escherichia coli. Expression_system_taxid: 562
|
|
|
Chain:
A
(306 residues)
|
|
|
|
|
|
The co-crystal structure of severe acute respiratory syndrome coronavirus 3c like protease with aldehyde m14
|
|
|
Source: Human sars coronavirus. Sars-cov. Organism_taxid: 694009. Gene: 1a. Expressed in: escherichia coli. Expression_system_taxid: 562
|
|
|
Chain:
A
(306 residues)
|
|
|
|
|
|
The protein of cat virus
|
|
|
Source: Feline infectious peritonitis virus. Organism_taxid: 11135. Gene: 1b, orf1a. Expressed in: escherichia coli. Expression_system_taxid: 562
|
|
|
Chains:
B, A, C, D
(104 residues)
|
|
|
|
|
|
The nsp1 protein of a new porcine coronavirus
|
|
|
Source: Swine acute diarrhea syndrome coronavirus. Organism_taxid: 2032731. Gene: orf1ab, orf1ab. Expressed in: escherichia coli. Expression_system_taxid: 562
|
|
|
Chains:
A, B
(101 residues)
|
|
|
|
|
|
Usp14 catalytic domain mutant c114s
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: usp14, tgt. Expressed in: escherichia coli bl21(de3). Expression_system_taxid: 469008
|
|
|
Chains:
A, B, C, D, E, F
(331 residues)
|
|
|
|
|
|
Usp7 in complex with a novel inhibitor
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: usp7, hausp. Expressed in: escherichia coli. Expression_system_taxid: 562
|
|
|
Chains:
A, B
(338 residues)
|
|
|
|
|
|
Structure of hsv2 viron capsid portal vertex
|
|
|
Source: Human herpesvirus 2. Hhv-2. Organism_taxid: 10310. Organism_taxid: 10310
|
|
|
Chains:
n, o
(47 residues)
|
|
|
|
|
|
Structure of hsv2 c-capsid portal vertex
|
|
|
Source: Human herpesvirus 2. Hhv-2. Organism_taxid: 10310. Organism_taxid: 10310
|
|
|
Chains:
P, Q
(47 residues)
|
|
|
|
|
|
Crystal structure of a tylonycteris bat coronavirus hku4 macrodomain in complex with adenosine diphosphate ribose (adp-ribose)
|
|
|
Source: Bat coronavirus hku4. Btcov. Organism_taxid: 694007. Gene: rep, 1a-1b. Expressed in: escherichia coli bl21(de3). Expression_system_taxid: 469008. Expression_system_cell_line: bl21(de3)plyss.
|
|
|
Chains:
A, B
(162 residues)
|
|
|
|
|
|
Crystal structure of tylonycteris bat coronavirus hku4 macrodomain in complex with nicotinamide adenine dinucleotide (NAD+)
|
|
|
Source: Bat coronavirus hku4. Btcov. Organism_taxid: 694007. Gene: rep, 1a-1b. Expressed in: escherichia coli bl21(de3). Expression_system_taxid: 469008. Expression_system_cell_line: bl21(de3)plyss.
|
|
|
Chains:
A, B
(162 residues)
|
|
|
|
|
|
Crystal structure of a tylonycteris bat coronavirus hku4 macrodomain in complex with adenosine diphosphate glucose (adp-glucose)
|
|
|
Source: Bat coronavirus hku4. Btcov. Organism_taxid: 694007. Gene: rep, 1a-1b. Expressed in: escherichia coli bl21(de3). Expression_system_taxid: 469008. Expression_system_cell_line: bl21(de3)plyss.
|
|
|
Chains:
A, B
(162 residues)
|
|
|
|
|
|
Structure of the usp15 deubiquitinase domain in complex with an affinity-matured inhibitory ubv
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: usp15, kiaa0529. Expressed in: escherichia coli. Expression_system_taxid: 562. Gene: ubc. Escherichia coli. Organism_taxid: 562.
|
|
|
Chains:
A, B
(316 residues)
|
|
|
|
|
|
Bat coronavirus hku4 sud-c
|
|
|
Source: Bat coronavirus hku4. Btcov. Organism_taxid: 694007. Gene: rep, 1a-1b. Expressed in: escherichia coli bl21(de3). Expression_system_taxid: 469008.
|
|
|
Chain:
A
(81 residues)
|
|
|
|
|
|
Structure of usp5 zinc-finger ubiquitin binding domain co-crystallized with (4-oxoquinazolin-3(4h)-yl)acetic acid
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: usp5, isot. Expressed in: escherichia coli. Expression_system_taxid: 562
|
|
|
Chains:
A, B
(115 residues)
|
|
|
|
|
|
X-ray structure of pedv papain-like protease 2
|
|
|
Source: Porcine epidemic diarrhea virus. Organism_taxid: 28295. Expressed in: escherichia coli bl21. Expression_system_taxid: 511693
|
|
|
Chain:
A
(248 residues)
|
|
|
|
|
|
Sars-coronavirus nsp12 bound to nsp7 and nsp8 co-factors
|
|
|
Source: Human sars coronavirus. Sars-cov. Organism_taxid: 227859. Gene: rep, 1a-1b. Expressed in: spodoptera frugiperda. Expression_system_taxid: 7108. Expression_system_cell_line: sf21. Gene: 1a. Expressed in: escherichia coli bl21.
|
|
|
Chains:
A, B, C, D
(793 residues)
|
|
|
|
|
|
Sars-coronavirus nsp12 bound to nsp8 co-factor
|
|
|
Source: Human sars coronavirus. Sars-cov. Organism_taxid: 227859. Gene: rep, 1a-1b. Expressed in: spodoptera frugiperda. Expression_system_taxid: 7108. Expression_system_cell_line: sf21. Gene: 1a. Expressed in: escherichia coli bl21.
|
|
|
Chains:
A, B
(715 residues)
|
|
|
|
|
|
Structure of the kupe virus otu bound to thE C-terminal domain of sheep isg15
|
|
|
Source: Kupe virus. Organism_taxid: 498356. Expressed in: escherichia coli. Expression_system_taxid: 562. Ovis aries. Sheep. Organism_taxid: 9940. Gene: isg17. Expression_system_taxid: 562
|
|
|
Chains:
A, C, E, G
(158 residues)
|
|
|
|
|
|
Herpes simplex virus type 1 (hsv-1) portal vertex-adjacent capsid/catc, asymmetric unit
|
|
|
Source: Human herpesvirus 1 strain kos. Hhv-1. Organism_taxid: 10306. Strain: kos. Strain: kos
|
|
|
Chains:
O, B
(48 residues)
|
|
|
|
|
|
Crystal structure of ubl123 with an ezh2 peptide
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: usp7, hausp. Expressed in: escherichia coli bl21(de3). Expression_system_taxid: 469008. Synthetic: yes. Organism_taxid: 9606
|
|
|
Chains:
A, B
(341 residues)
|
|
|
|
|
|
Structure of usp5 zinc-finger ubiquitin binding domain co-crystallized with 2-(4-oxoquinazolin-3(4h)-yl)propanoic acid
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: usp5, isot. Expressed in: escherichia coli bl21. Expression_system_taxid: 511693.
|
|
|
Chain:
A
(117 residues)
|
|
|
|
|
|
Human josephin-2 in complex with ubiquitin
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: josd2, sbbi54. Expressed in: escherichia coli bl21(de3). Expression_system_taxid: 469008. Gene: ubb.
|
|
|
Chain:
A
(152 residues)
|
|
|
|
|
|
Kaposi's sarcoma-associated herpesvirus (kshv), c5 portal vertex structure
|
|
|
Source: Human herpesvirus 8. Hhv-8. Organism_taxid: 868565. Strain: gk18. Strain: gk18
|
|
|
Chains:
n, o
(40 residues)
|
|
|
|
|
|
Kaposi's sarcoma-associated herpesvirus (kshv), c1 penton vertex register, catc-binding structure
|
|
|
Source: Human herpesvirus 8. Hhv-8. Organism_taxid: 868565. Strain: gk18. Strain: gk18
|
|
|
Chains:
n, o
(40 residues)
|
|
|
|
|
|
Uchl3 in complex with synthetic, k27-linked diubiquitin
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: uchl3. Expressed in: escherichia coli bl21(de3). Expression_system_taxid: 469008. Synthetic: yes. Organism_taxid: 9606
|
|
|
Chains:
A, D
(227 residues)
|
|
|
|
|
|
Crystal structure of the sir4 h-brct domain in complex with ubp10 pt123 peptide
|
|
|
Source: Saccharomyces cerevisiae. Baker's yeast. Organism_taxid: 4932. Gene: sir4, asd1, ste9, uth2, ydr227w, yd9934.12. Expressed in: escherichia coli bl21(de3). Expression_system_taxid: 469008. Expression_system_variant: bl21 de3 star. Synthetic: yes. Saccharomyces cerevisiae (strain atcc 204508 /
|
|
|
Chains:
I, L
(11 residues)
|
|
|
|
|
|
Structure of the otulincat c129a - snx27 pdz domain complex.
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: otulin, fam105b. Expressed in: escherichia coli bl21(de3). Expression_system_taxid: 469008. Expression_system_variant: rosetta. Gene: snx27, kiaa0488, my014. Expressed in: escherichia coli.
|
|
|
Chains:
A, B
(274 residues)
|
|
|
|
|
|
Saga dub module bound to a ubiqitinated nucleosome
|
|
|
Source: Xenopus laevis. African clawed frog. Organism_taxid: 8355. Expressed in: escherichia coli. Expression_system_taxid: 562. Gene: hist1h2aj, loc494591. Western clawed frog. Synthetic: yes. Synthetic construct.
|
|
|
Chain:
K
(445 residues)
|
|
|
|
|
|
Structure of saga bound to tbp, including spt8 and dub
|
|
|
Source: Komagataella phaffii (strain gs115 / atcc 20864). Yeast. Organism_taxid: 644223. Gene: spt15. Expressed in: escherichia coli. Expression_system_taxid: 562. Strain: gs115 / atcc 20864. Yeast, pichia pastoris.
|
|
|
Chain:
Q
(482 residues)
|
|
|
|
|
|
Crystal structure of mindy1 in complex with lys48 linked di-ubiquitin
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: mindy1, fam63a, kiaa1390. Expressed in: escherichia coli. Expression_system_taxid: 562. Gene: ubc. Expression_system_taxid: 562
|
|
|
Chain:
A
(262 residues)
|
|
|
|
|
|
Crystal structure of mindy1 mutant (p138a) in complex with lys48 linked di-ubiquitin
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: mindy1, fam63a, kiaa1390. Expressed in: escherichia coli. Expression_system_taxid: 562. Gene: ubc. Expression_system_taxid: 562
|
|
|
Chain:
A
(263 residues)
|
|
|
|
|
|
2.05 a resolution structure of mers 3cl protease in complex with inhibitor 6b
|
|
|
Source: Middle east respiratory syndrome-related coronavirus. Organism_taxid: 1335626. Gene: orf1a. Expressed in: escherichia coli bl21. Expression_system_taxid: 511693.
|
|
|
Chains:
A, B
(297 residues)
|
|
|
|
|
|
2.25 a resolution structure of mers 3cl protease in complex with inhibitor 6d
|
|
|
Source: Middle east respiratory syndrome-related coronavirus. Organism_taxid: 1335626. Gene: orf1a. Expressed in: escherichia coli bl21. Expression_system_taxid: 511693.
|
|
|
Chains:
A, B
(296 residues)
|
|
|
|
|
|
1.95 a resolution structure of mers 3cl protease in complex with inhibitor 6g
|
|
|
Source: Middle east respiratory syndrome-related coronavirus. Organism_taxid: 1335626. Gene: orf1a. Expressed in: escherichia coli bl21. Expression_system_taxid: 511693.
|
|
|
Chains:
A, B
(297 residues)
|
|
|
|
|
|
2.30 a resolution structure of mers 3cl protease in complex with inhibitor 6h
|
|
|
Source: Middle east respiratory syndrome-related coronavirus. Organism_taxid: 1335626. Gene: orf1a. Expressed in: escherichia coli bl21. Expression_system_taxid: 511693.
|
|
|
Chains:
A, B
(298 residues)
|
|
|
|
|
|
2.26 a resolution structure of mers 3cl protease in complex with inhibitor 7i
|
|
|
Source: Middle east respiratory syndrome-related coronavirus. Organism_taxid: 1335626. Gene: orf1a. Expressed in: escherichia coli bl21. Expression_system_taxid: 511693.
|
|
|
Chains:
A, B
(299 residues)
|
|
|
|
|
|
2.20 a resolution structure of mers 3cl protease in complex with inhibitor 7j
|
|
|
Source: Middle east respiratory syndrome-related coronavirus. Organism_taxid: 1335626. Gene: orf1a. Expressed in: escherichia coli bl21. Expression_system_taxid: 511693.
|
|
|
Chains:
A, B
(300 residues)
|
|
|
|
|
|
Usp7 in complex with ligand compound 18
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: usp7, hausp. Expressed in: escherichia coli. Expression_system_taxid: 562
|
|
|
Chains:
A, B
(341 residues)
|
|
|
|
|
|
Usp7 in complex with ligand compound 23
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: usp7, hausp. Expressed in: escherichia coli. Expression_system_taxid: 562
|
|
|
Chains:
A, B
(329 residues)
|
|
|
|
|
|
Usp7 in complex with ligand compound 1
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: usp7, hausp. Expressed in: escherichia coli. Expression_system_taxid: 562
|
|
|
Chains:
A, B
(341 residues)
|
|
|
|
|
|
Usp7 in complex with ligand compound 7
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: usp7, hausp. Expressed in: escherichia coli. Expression_system_taxid: 562
|
|
|
Chains:
A, B
(337 residues)
|
|
|
|
|
|
Usp7 in complex with ligand compound 14
|
|
|
Source: Synthetic: yes. Homo sapiens. Human. Organism_taxid: 9606
|
|
|
Chains:
A, B
(335 residues)
|
|
|
|
|
|
1.65 a resolution structure of sars-cov 3cl protease in complex with inhibitor 7j
|
|
|
Source: Human sars coronavirus. Sars-cov. Organism_taxid: 694009. Gene: 1a. Expressed in: escherichia coli bl21. Expression_system_taxid: 511693.
|
|
|
Chains:
A, B
(302 residues)
|
|
|
|
|
|
Structures of capsid and capsid-associated tegument complex inside the epstein-barr virus
|
|
|
Source: Epstein-barr virus (strain b95-8). Hhv-4. Organism_taxid: 10377. Strain: b95-8. Strain: b95-8
|
|
|
Chains:
y, z
(37 residues)
|
|
|
|
|
|
Structures of capsid and capsid-associated tegument complex inside the epstein-barr virus
|
|
|
Source: Epstein-barr virus (strain b95-8). Hhv-4. Organism_taxid: 10377. Strain: b95-8. Strain: b95-8
|
|
|
Chains:
y, z
(37 residues)
|
|
|
|
|
|
Structure of sars-cov main protease bound to potent broad-spectrum non-covalent inhibitor x77
|
|
|
Source: Sars-cov-2. Organism_taxid: 2697049. Strain: covid-19. Expressed in: escherichia coli bl21(de3). Expression_system_taxid: 469008.
|
|
|
Chain:
A
(306 residues)
|
|
|
|
|
|
Structure of pedv main protease bound to potent broad-spectrum non- covalent inhibitor x77
|
|
|
Source: Porcine epidemic diarrhea virus. Organism_taxid: 28295. Gene: orf1ab. Expressed in: escherichia coli. Expression_system_taxid: 562
|
|
|
Chains:
A, B
(302 residues)
|
|
|
|
|
|
Structure of sars main protease bound to inhibitor x47
|
|
|
Source: Sars coronavirus urbani. Organism_taxid: 228330. Expressed in: escherichia coli bl21(de3). Expression_system_taxid: 469008.
|
|
|
Chain:
A
(306 residues)
|
|
|
|
|
|
Covalent complex of sars-cov main protease with n-[(2s)-1-({(2s,3s)-3, 4-dihydroxy-1-[(3s)-2-oxopyrrolidin-3-yl]butan-2-yl}amino)-4-methyl- 1-oxopentan-2-yl]-4-methoxy-1h-indole-2-carboxamide
|
|
|
Source: Human sars coronavirus. Sars-cov. Organism_taxid: 694009. Gene: 1a. Expressed in: escherichia coli. Expression_system_taxid: 562
|
|
|
Chains:
A, B
(301 residues)
|
|
|
|
|
|
Covalent complex of sars-cov main protease with 4-methoxy-n-[(2s)-4- methyl-1-oxo-1-({(2s)-3-oxo-1-[(3s)-2-oxopyrrolidin-3-yl]butan-2- yl}amino)pentan-2-yl]-1h-indole-2-carboxamide
|
|
|
Source: Human sars coronavirus. Sars-cov. Organism_taxid: 694009. Gene: 1a. Expressed in: escherichia coli. Expression_system_taxid: 562
|
|
|
Chains:
A, B
(301 residues)
|
|
|
|
|
|
Covalent complex of sars-cov main protease with ethyl (4r)-4-({n-[(4- methoxy-1h-indol-2-yl)carbonyl]-l-leucyl}amino)-5-[(3s)-2- oxopyrrolidin-3-yl]pentanoate
|
|
|
Source: Human sars coronavirus. Sars-cov. Organism_taxid: 694009. Gene: 1a. Expressed in: escherichia coli. Expression_system_taxid: 562
|
|
|
Chains:
A, B
(300 residues)
|
|
|
|
|
|
Crystal structure of mindy1 t335d mutant
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: mindy1, fam63a, kiaa1390. Expressed in: escherichia coli. Expression_system_taxid: 562
|
|
|
Chain:
A
(257 residues)
|
|
|
|
|
|
Crystal structure of the complex resulting from the reaction between the sars-cov main protease and tert-butyl (1-((s)-3-cyclohexyl-1-(((s)-4-(cyclopropylamino)-3,4-dioxo-1-((s)-2-oxopyrrolidin-3-yl)butan-2-yl)amino)-1-oxopropan-2-yl)-2-oxo-1,2-dihydropyridin-3-yl)carbamate
|
|
|
Source: Severe acute respiratory syndrome coronavirus
|
|
|
Chain:
A
(306 residues)
|
|
|
|
|
|
Structure of a human 48s translational initiation complex - eif3
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Organism_taxid: 9606
|
|
|
Chain:
4
(257 residues)
|
|
|
|
|
|
Crystal structure of mindy1 mutant-y114f
|
|
|
Source: Homo sapiens. Organism_taxid: 9606. Gene: mindy1, fam63a, kiaa1390. Expressed in: escherichia coli. Expression_system_taxid: 562
|
|
|
Chain:
A
(259 residues)
|
|
|
|
|
|
X-ray structure of turnip yellow mosaic virus pro/dub in complex with ubiquitin
|
|
|
Source: Turnip yellow mosaic virus. Organism_taxid: 12154. Expressed in: escherichia coli. Expression_system_taxid: 562. Homo sapiens. Human. Organism_taxid: 9606. Gene: ubc. Expression_system_taxid: 562
|
|
|
Chains:
A, C
(145 residues)
|
|
|
|
|
|
Crystal structure of sars-cov macrodomain ii in complex with human paip1
|
|
|
Source: Severe acute respiratory syndrome coronavirus. Sars-cov. Organism_taxid: 694009. Gene: 1a. Expressed in: escherichia coli k-12. Expression_system_taxid: 83333. Homo sapiens. Human. Organism_taxid: 9606.
|
|
|
Chain:
A
(128 residues)
|
|
|
|
|
|
Crystal structure of deubiquitinase mindy2
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: mindy2, fam63b, kiaa1164. Expressed in: escherichia coli. Expression_system_taxid: 562
|
|
|
Chains:
A, B, C, D
(252 residues)
|
|
|
|
|
|
Crystal structure of mindy2 (c266a) in complex with lys48 linked di- ubiquitin (k48-ub2)
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: mindy2, fam63b, kiaa1164. Expressed in: escherichia coli. Expression_system_taxid: 562. Gene: ubc. Expression_system_taxid: 562
|
|
|
Chains:
A, B
(260 residues)
|
|
|
|
|
|
Crystal structure of mindy1 mutant-p138a
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: mindy1, fam63a, kiaa1390. Expressed in: escherichia coli. Expression_system_taxid: 562
|
|
|
Chain:
A
(256 residues)
|
|
|
|
|
|
Crystal structure of truncated usp1-uaf1
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: wdr48, kiaa1449, uaf1. Expressed in: spodoptera frugiperda. Expression_system_taxid: 7108. Expression_system_cell_line: sf21. Gene: usp1. Expression_system_cell_line: sf21
|
|
|
Chains:
B, D
(302 residues)
|
|
|
|
|
|
Cryo-em structure of usp1-uaf1 bound to mono-ubiquitinated fancd2, and fanci
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: fanci, kiaa1794. Expressed in: spodoptera frugiperda. Expression_system_taxid: 7108. Expression_system_cell_line: sf21. Gene: fancd2, facd. Gene: uba52, ubcep2.
|
|
|
Chain:
D
(341 residues)
|
|
|
|
|
|
Crystal structure of truncated usp1-uaf1 reacted with ubiquitin-prg
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: wdr48, kiaa1449, uaf1. Expressed in: spodoptera frugiperda. Expression_system_taxid: 7108. Expression_system_cell_line: sf21. Gene: usp1. Gene: ubb.
|
|
|
Chains:
B, E
(337 residues)
|
|
|
|
|
|
Crystal structure of sars-cov-2 macrodomain in complex with remdesivir metabolite gs-441524
|
|
|
Source: Severe acute respiratory syndrome coronavirus 2. Organism_taxid: 2697049. Gene: rep, 1a-1b. Expressed in: escherichia coli bl21(de3). Expression_system_taxid: 469008. Expression_system_variant: -r3-prare2.
|
|
|
Chains:
( residues)
|
|
|
|
|
|
Epstein-barr virus, c5 portal vertex
|
|
|
Source: Epstein-barr virus (strain b95-8). Hhv-4. Organism_taxid: 10377. Strain: b95-8. Strain: b95-8
|
|
|
Chains:
B, O
(35 residues)
|
|
|
|
|
|
Epstein-barr virus, c1 portal-proximal penton vertex, catc binding
|
|
|
Source: Epstein-barr virus (strain b95-8). Hhv-4. Organism_taxid: 10377. Strain: b95-8. Strain: b95-8
|
|
|
Chains:
B, O
(35 residues)
|
|
|
|
|
|
The crystal structure of human usp7 usp domain from biortus
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: usp7, hausp. Expressed in: escherichia coli. Expression_system_taxid: 562
|
|
|
Chains:
A, B
(337 residues)
|
|
|
|
|
|
The newly emerged sars-like coronavirus hcov-emc also has an "achilles' heel": current effective inhibitor targeting a 3c-like protease
|
|
|
Source: Middle east respiratory syndrome-related coronavirus. Mers-cov. Organism_taxid: 1335626. Expressed in: escherichia coli bl21(de3). Expression_system_taxid: 469008. Synthetic: yes. Synthetic construct. Organism_taxid: 32630
|
|
|
Chains:
B, A
(299 residues)
|
|
|
|
|
|
Crystal structure of sars 3c-like protease in apo form
|
|
|
Source: Human sars coronavirus. Sars-cov. Organism_taxid: 694009. Gene: 1a. Expressed in: escherichia coli bl21(de3). Expression_system_taxid: 469008.
|
|
|
Chains:
A, B
(298 residues)
|
|
|
|
|
|
Crystal structure of mers-cov 3cl protease in spacegroup p212121
|
|
|
Source: Middle east respiratory syndrome-related coronavirus. Mers-cov. Organism_taxid: 1335626. Expressed in: escherichia coli bl21. Expression_system_taxid: 511693.
|
|
|
Chains:
A, B
(295 residues)
|
|
|
|
|
|
Crystal structure of mers-cov 3cl protease (c148a) in spacegroup p212121
|
|
|
Source: Middle east respiratory syndrome-related coronavirus. Mers-cov. Organism_taxid: 1335626. Expressed in: escherichia coli bl21. Expression_system_taxid: 511693.
|
|
|
Chains:
A, B
(279 residues)
|
|
|
|
|
|
Crystal structure of mers-cov 3cl protease (c148a) in spacegroup p212121,ph 9.0
|
|
|
Source: Middle east respiratory syndrome-related coronavirus. Mers-cov. Organism_taxid: 1335626. Expressed in: escherichia coli bl21. Expression_system_taxid: 511693.
|
|
|
Chains:
A, B
(279 residues)
|
|
|
|
|
|
Crystal structure of hcov-nl63 3c-like protease,ph5.0
|
|
|
Source: Human coronavirus nl63. Hcov-nl63. Organism_taxid: 277944. Expressed in: escherichia coli bl21. Expression_system_taxid: 511693.
|
|
|
Chains:
A, B
(299 residues)
|
|
|
|
|
|
Crystal structure of human coronavirus nl63 3c-like protease
|
|
|
Source: Human coronavirus nl63. Hcov-nl63. Organism_taxid: 277944. Expressed in: escherichia coli bl21. Expression_system_taxid: 511693.
|
|
|
Chains:
A, B
(299 residues)
|
|
|
|
|
|
Crystal structure of hcov-nl63 3c-like protease,ph5.2
|
|
|
Source: Human coronavirus nl63. Hcov-nl63. Organism_taxid: 277944. Expressed in: escherichia coli bl21. Expression_system_taxid: 511693.
|
|
|
Chains:
A, B
(299 residues)
|
|
|
|
|
|
Crystal structure of hcov-nl63 3c-like protease,ph5.6
|
|
|
Source: Human coronavirus nl63. Hcov-nl63. Organism_taxid: 277944. Expressed in: escherichia coli bl21. Expression_system_taxid: 511693.
|
|
|
Chains:
A, B
(299 residues)
|
|
|
|
|
|
Multi-state structure determination and dynamics analysis elucidate a new ubiquitin-recognition mechanism of yeast ubiquitin c-terminal hydrolase.
|
|
|
Source: Saccharomyces cerevisiae. Organism_taxid: 4932. Expressed in: escherichia coli bl21(de3). Expression_system_taxid: 469008.
|
|
|
Chain:
A
(236 residues)
|
|
|
|
|
|
Crystal structure of sars-cov 3clpro in complex with the non-covalent inhibitor wu-04
|
|
|
Source: Human sars coronavirus. Sars-cov. Organism_taxid: 694009. Gene: 1a. Expressed in: escherichia coli. Expression_system_taxid: 562
|
|
|
Chain:
A
(306 residues)
|
|
|
|
|
|
Crystal structure of mers-cov 3clpro in complex with the non-covalent inhibitor wu-04
|
|
|
Source: Middle east respiratory syndrome coronavirus. Organism_taxid: 1335626. Gene: orf1ab. Expressed in: escherichia coli. Expression_system_taxid: 562
|
|
|
Chains:
A, B, C, D
(304 residues)
|
|
|
|
|
|
Crystal structure of hcov-nl63 3c-like protease in complex with an inhibitor shikonin
|
|
|
Source: Human coronavirus nl63. Hcov-nl63. Organism_taxid: 277944. Expressed in: escherichia coli bl21. Expression_system_taxid: 511693.
|
|
|
Chains:
A, B
(299 residues)
|
|
|
|
|
|
Crystal structure of sars coronavirus main protease in complex with an inhibitor shikonin
|
|
|
Source: Severe acute respiratory syndrome-related coronavirus. Sars-cov. Organism_taxid: 694009. Expressed in: escherichia coli bl21(de3). Expression_system_taxid: 469008.
|
|
|
Chains:
A, B
(298 residues)
|
|
|
|
|
|
C5 portal vertex in the enveloped virion capsid
|
|
|
Source: Human cytomegalovirus. Hhv-5, human herpesvirus 5. Organism_taxid: 10359. Organism_taxid: 10359
|
|
|
Chains:
H, P
(20 residues)
|
|
|
|
|
|
Porcine epidemic diarrhea virus papain-like protease 2 c44s mutant in complex with mono ubiquitin
|
|
|
Source: Porcine epidemic diarrhea virus. Organism_taxid: 28295. Expressed in: escherichia coli. Expression_system_taxid: 562. Bos taurus. Bovine. Organism_taxid: 9913
|
|
|
Chains:
A, B
(217 residues)
|
|
|
|
|
|
Crystal structure of ibv nsp2
|
|
|
Source: Infectious bronchitis virus. Organism_taxid: 11120. Expressed in: escherichia coli. Expression_system_taxid: 562
|
|
|
Chains:
A, B
(584 residues)
|
|
|
|
|
|
Crystal structure of n-terminus of the non-structural protein 2 from sars coronavirus
|
|
|
Source: Severe acute respiratory syndrome-related coronavirus. Organism_taxid: 694009. Gene: 1a. Expressed in: escherichia coli bl21(de3). Expression_system_taxid: 469008.
|
|
|
Chain:
A
(276 residues)
|
|
|
|
|
|
Crystal structure of c-terminus of the non-structural protein 2 from sars coronavirus
|
|
|
Source: Severe acute respiratory syndrome-related coronavirus. Organism_taxid: 694009. Gene: 1a. Expressed in: escherichia coli bl21(de3). Expression_system_taxid: 469008
|
|
|
Chain:
A
(524 residues)
|
|
|
|
|
|
Structure of the hazara virus otu bound to ubiquitin
|
|
|
Source: Hazara orthonairovirus. Organism_taxid: 1980522. Expressed in: escherichia coli. Expression_system_taxid: 562. Homo sapiens. Human. Organism_taxid: 9606. Gene: ubb. Expression_system_taxid: 562
|
|
|
Chains:
A, C, E, G
(157 residues)
|
|
|
|
|
|
1.85 a resolution structure of sars-cov 3cl protease in complex with deuterated gc376
|
|
|
Source: Human sars coronavirus. Sars-cov. Organism_taxid: 694009. Gene: 1a. Expressed in: escherichia coli bl21. Expression_system_taxid: 511693.
|
|
|
Chain:
A
(296 residues)
|
|
|
|
|
|
1.70 a resolution structure of sars-cov 3cl protease in complex with a deuterated gc376 alpha-ketoamide analog (compound 5)
|
|
|
Source: Human sars coronavirus. Sars-cov. Organism_taxid: 694009. Gene: 1a. Expressed in: escherichia coli bl21. Expression_system_taxid: 511693.
|
|
|
Chains:
A, B
(298 residues)
|
|
|
|
|
|
N-terminal finger stabilizes feline drug gc376 in coronavirus 3cl protease
|
|
|
Source: Severe acute respiratory syndrome coronavirus. Sars-cov. Organism_taxid: 694009. Gene: rep, 1a-1b. Expressed in: escherichia coli o103:h2. Expression_system_taxid: 585395.
|
|
|
Chain:
A
(304 residues)
|
|
|
|
|
|
N-terminal finger stabilizes feline drug gc376 in coronavirus 3cl protease
|
|
|
Source: Severe acute respiratory syndrome coronavirus. Sars-cov. Organism_taxid: 694009. Gene: rep, 1a-1b. Expressed in: escherichia coli o103:h2. Expression_system_taxid: 585395.
|
|
|
Chain:
A
(303 residues)
|
|
|
|
|
|
Crystal structure of the sars cov-1 papain-like protease in complex with peptide inhibitor vir250
|
|
|
Source: Severe acute respiratory syndrome coronavirus. Sars-cov. Organism_taxid: 694009. Gene: 1a. Expressed in: escherichia coli. Expression_system_taxid: 469008. Synthetic: yes. Synthetic construct. Organism_taxid: 32630
|
|
|
Chain:
D
(306 residues)
|
|
|
|
|
|
Crystal structure of the sars cov-1 papain-like protease in complex with peptide inhibitor vir251
|
|
|
Source: Severe acute respiratory syndrome coronavirus. Sars-cov. Organism_taxid: 694009. Gene: 1a. Expressed in: escherichia coli. Expression_system_taxid: 469008. Synthetic: yes. Synthetic construct. Organism_taxid: 32630
|
|
|
Chains:
B, A
(312 residues)
|
|
|
|
|
|
Sars-cov-1 3clpro in complex with n-(4-(1h-imidazol-4-yl)phenyl)-2-(1h-benzo[d][1,2,3]triazol-1-yl)-n-(thiophen-3-ylmethyl)acetamide
|
|
|
Source: Severe acute respiratory syndrome coronavirus
|
|
|
Chain:
A
(306 residues)
|
|
|
|
|
|
Sars-cov-1 3clpro in complex with 2-(1h-benzo[d][1,2,3]triazol-1-yl)-n-(4-(pyridin-3-yl)phenyl)-n-(thiophen-3-ylmethyl)acetamide'
|
|
|
Source: Severe acute respiratory syndrome coronavirus
|
|
|
Chain:
A
(306 residues)
|
|
|
|
|
|
Sars-cov-1 3clpro in complex with n-(4-(1h-pyrazol-4-yl)phenyl)-2-(1h-benzo[d][1,2,3]triazol-1-yl)-n-(thiophen-3-ylmethyl)acetamide'
|
|
|
Source: Severe acute respiratory syndrome coronavirus
|
|
|
Chain:
A
(306 residues)
|
|
|
|
|
|
Sars-cov-1 3clpro in complex with 2-(1h-benzo[d][1,2,3]triazol-1-yl)-n-(3-chlorobenzyl)-n-(4-(2-oxo-1,2-dihydropyridin-3-yl)phenyl)acetamide
|
|
|
Source: Severe acute respiratory syndrome coronavirus
|
|
|
Chain:
A
(306 residues)
|
|
|
|
|
|
X-ray structure of pedv papain-like protease 2 bound to ub-pa
|
|
|
Source: Porcine epidemic diarrhea virus. Organism_taxid: 28295. Gene: orf1ab. Expressed in: escherichia coli 'bl21-gold(de3)plyss ag'. Expression_system_taxid: 866768. Homo sapiens. Human. Organism_taxid: 9606. Gene: ubb.
|
|
|
Chains:
A, C, E, G, I, K, M, O
(233 residues)
|
|
|
|
|
|
Maize rayado fino virus protease
|
|
|
Source: Maize rayado fino virus. Mrfv. Organism_taxid: 59749. Gene: orf1. Expressed in: escherichia coli bl21(de3). Expression_system_taxid: 469008
|
|
|
Chains:
A, B
(146 residues)
|
|
|
|
|
|
Maize rayado fino virus protease in complex with ubiquitin
|
|
|
Source: Maize rayado fino virus. Mrfv. Organism_taxid: 59749. Gene: orf1. Expressed in: escherichia coli bl21(de3). Expression_system_taxid: 469008. Homo sapiens. Human. Organism_taxid: 9606.
|
|
|
Chain:
A
(144 residues)
|
|
|
|
|
|
Structure of usp5 zinc-finger ubiquitin binding domain co-crystallized with 4-(4-(4-(3,4-difluoro-phenyl)-piperidin-1-ylsulfonyl)-phenyl)-4- oxo-butanoic acid
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: usp5, isot. Expressed in: escherichia coli. Expression_system_taxid: 562
|
|
|
Chains:
A, B
(115 residues)
|
|
|
|
|
|
Structure of usp5 zinc-finger ubiquitin binding domain co-crystallized with (2-fluoro-4-((4-phenylpiperidin-1-yl)sulfonyl)benzoyl)glycine
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: usp5, isot. Expressed in: escherichia coli. Expression_system_taxid: 562
|
|
|
Chain:
A
(111 residues)
|
|
|
|
|
|
Structure of usp5 zinc-finger ubiquitin binding domain co-crystallized with (5-((4-(4-chlorophenyl)piperidin-1-yl)sulfonyl)picolinoyl) glycine
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: usp5, isot. Expressed in: escherichia coli. Expression_system_taxid: 562
|
|
|
Chains:
A, B
(113 residues)
|
|
|
|
|
|
Oc43 coronavirus methyltransferase
|
|
|
Source: Human coronavirus oc43. Hcov-oc43. Organism_taxid: 31631. Gene: rep, 1a-1b. Expressed in: escherichia coli bl21(de3). Expression_system_taxid: 469008. Gene: 1a. Expression_system_taxid: 469008
|
|
|
Chains:
A, B
(295 residues)
|
|
|
|
|
|
Crystal structure of mindy2 (c266a) in complex with lys48-linked penta-ubiquitin (k48-ub5)
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: mindy2, fam63b, kiaa1164. Expressed in: escherichia coli bl21. Expression_system_taxid: 511693. Gene: ubc. Expression_system_taxid: 511693
|
|
|
Chains:
A, G, M, S, Y, e, k
(262 residues)
|
|
|
|
|
|
Crystal structure of the zufsp family member mug105
|
|
|
Source: Schizosaccharomyces pombe (strain 972 / atcc 24843). Fission yeast. Organism_taxid: 284812. Strain: 972 / atcc 24843. Gene: mug105, spac25h1.04. Expressed in: escherichia coli. Expression_system_taxid: 562
|
|
|
Chains:
A, B
(244 residues)
|
|
|
|
|
|
Crystal structure of the covalent complex between tribolium castaneum deubiquitinase zup and ubiquitin-pa
|
|
|
Source: Tribolium castaneum. Red flour beetle. Organism_taxid: 7070. Gene: tcasga2_tc005718. Expressed in: escherichia coli. Expression_system_taxid: 562. Homo sapiens. Human. Organism_taxid: 9606.
|
|
|
Chains:
A, C
(365 residues)
|
|
|
|
|
|
Cryoem structure of DNA polymerase alpha - primase bound to sars cov nsp1
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: pola1, pola. Expressed in: spodoptera frugiperda. Expression_system_taxid: 7108. Gene: pola2. Gene: prim1. Gene: prim2, prim2a.
|
|
|
Chain:
E
(105 residues)
|
|
|
|
|
|
Structure of cyld cap-gly3 (467-565) bound to ub; orthorhobic space group
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: uba52, ubcep2. Expressed in: escherichia coli. Expression_system_taxid: 562. Gene: cyld. Expressed in: escherichia coli bl21(de3). Expression_system_taxid: 469008.
|
|
|
Chains:
B, D
(95 residues)
|
|
|
|
|
|
Structure of cyld cap-gly3 (467-552) bound to ub; tetragonal space group
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: cyld, cyld1, kiaa0849, hspc057. Expressed in: escherichia coli bl21(de3). Expression_system_taxid: 469008. Expression_system_variant: rosetta. Gene: ubc. Expression_system_variant: rosetta
|
|
|
Chain:
B
(84 residues)
|
|
|
|
|
|
Structure of the 26s proteasome-ubp6 complex in the si state (core particle and lid)
|
|
|
Source: Saccharomyces cerevisiae. Baker's yeast. Organism_taxid: 4932. Strain: atcc 204508 / s288c. Strain: atcc 204508 / s288c
|
|
|
Chain:
V
(289 residues)
|
|
|
|
|
|
26s proteasome wt-ubp6-ubvs complex in the si state (atpases, rpn1, ubp6, and ubvs)
|
|
|
Source: Saccharomyces cerevisiae. Baker's yeast. Organism_taxid: 4932. Strain: atcc 204508 / s288c. Gene: ubp6, gi527_g0002094. Expressed in: escherichia coli. Expression_system_taxid: 562. Homo sapiens. Human.
|
|
|
Chain:
8
(372 residues)
|
|
|
|
|
|
Usp15 d1d2 in catalytically-competent state bound to mitoxantrone stack (isoform 2)
|
|
|
Source: Homo sapiens. Organism_taxid: 9606. Gene: usp15. Expressed in: escherichia coli bl21(de3). Expression_system_taxid: 469008. Expression_system_variant: t1 resistant.
|
|
|
Chains:
A, B
(346 residues)
|
|
|
|
|
|
The crystal structure of papain-like protease of sars cov-2, c111s mutant, in complex with a lys48-linked di-ubiquitin
|
|
|
Source: Severe acute respiratory syndrome coronavirus 2. 2019-ncov. Organism_taxid: 2697049. Expressed in: escherichia coli bl21(de3). Expression_system_taxid: 469008. Homo sapiens. Human. Organism_taxid: 9606.
|
|
|
Chain:
A
(313 residues)
|
|
|
|
|
|
The crystal structure of papain-like protease of sars cov-2, c111s mutant, in complex with human isg15
|
|
|
Source: Severe acute respiratory syndrome coronavirus 2. 2019-ncov. Organism_taxid: 2697049. Expressed in: escherichia coli bl21(de3). Expression_system_taxid: 469008. Homo sapiens. Human. Organism_taxid: 9606.
|
|
|
Chains:
A, C, E, G, I
(312 residues)
|
|
|
|
|
|
X-ray structure of sars-cov main protease covalently modified by compound grl-0686
|
|
|
Source: Severe acute respiratory syndrome coronavirus. Sars-cov. Organism_taxid: 694009. Gene: 1a. Expressed in: escherichia coli bl21(de3). Expression_system_taxid: 469008
|
|
|
Chain:
A
(306 residues)
|
|
|
|
|
|
Btscov-rf1.2004 papain-like protease bound to the non-covalent inhibitor grl-0617
|
|
|
Source: Bat sars cov rf1/2004. Organism_taxid: 347537. Expressed in: escherichia coli bl21(de3). Expression_system_taxid: 469008
|
|
|
Chains:
A, B
(313 residues)
|
|
|
|
|
|
Btscov-rf1.2004 papain-like protease bound to the non-covalent inhibitor 37
|
|
|
Source: Bat sars cov rf1/2004. Organism_taxid: 347537. Expressed in: escherichia coli bl21(de3). Expression_system_taxid: 469008
|
|
|
Chain:
A
(314 residues)
|
|
|
|
|
|
Crystallization of feline coronavirus mpro with gc376 reveals mechanism of inhibition
|
|
|
Source: Feline coronavirus. Organism_taxid: 12663. Expressed in: escherichia coli. Expression_system_taxid: 562
|
|
|
Chains:
A, B
(299 residues)
|
|
|
|
|
|
Crystallization of feline coronavirus mpro with gc376 reveals mechanism of inhibition
|
|
|
Source: Feline coronavirus. Organism_taxid: 12663. Expressed in: escherichia coli. Expression_system_taxid: 562
|
|
|
Chains:
A, B
(302 residues)
|
|
|
|
|
|
Structure of mers 3cl protease in complex with inhibitor 8c
|
|
|
Source: Middle east respiratory syndrome-related coronavirus (isolate united kingdom/h123990006/2012). Mers-cov,betacoronavirus england 1. Organism_taxid: 1263720. Strain: isolate united kingdom/h123990006/2012. Gene: 1a. Expressed in: escherichia coli bl21. Expression_system_taxid: 511693.
|
|
|
Chains:
A, B
(302 residues)
|
|
|
|
|
|
Structure of mers 3cl protease in complex with inhibitor 9c
|
|
|
Source: Middle east respiratory syndrome-related coronavirus (isolate united kingdom/h123990006/2012). Mers-cov, betacoronavirus england 1. Organism_taxid: 1263720. Strain: isolate united kingdom/h123990006/2012. Gene: 1a. Expressed in: escherichia coli bl21. Expression_system_taxid: 511693.
|
|
|
Chains:
A, B
(306 residues)
|
|
|
|
|
|
Structure of mers 3cl protease in complex with inhibitor 10c
|
|
|
Source: Middle east respiratory syndrome-related coronavirus (isolate united kingdom/h123990006/2012). Mers-cov, betacoronavirus england 1. Organism_taxid: 1263720. Strain: isolate united kingdom/h123990006/2012. Gene: 1a. Expressed in: escherichia coli bl21. Expression_system_taxid: 511693.
|
|
|
Chain:
A
(302 residues)
|
|
|
|
|
|
Structure of mers 3cl protease in complex with inhibitor 14c
|
|
|
Source: Middle east respiratory syndrome-related coronavirus (isolate united kingdom/h123990006/2012). Mers-cov, betacoronavirus england 1. Organism_taxid: 1263720. Strain: isolate united kingdom/h123990006/2012. Gene: 1a. Expressed in: escherichia coli bl21. Expression_system_taxid: 511693.
|
|
|
Chain:
A
(302 residues)
|
|
|
|
|
|
Structure of mers 3cl protease in complex with the cyclopropane based inhibitor 13c
|
|
|
Source: Middle east respiratory syndrome-related coronavirus. Organism_taxid: 1335626. Gene: orf1a. Expressed in: escherichia coli bl21. Expression_system_taxid: 511693.
|
|
|
Chain:
A
(302 residues)
|
|
|
|
|
|
Structure of mers 3cl protease in complex with the cyclopropane based inhibitor 14d
|
|
|
Source: Middle east respiratory syndrome-related coronavirus. Organism_taxid: 1335626. Gene: orf1a. Expressed in: escherichia coli bl21. Expression_system_taxid: 511693.
|
|
|
Chain:
A
(302 residues)
|
|
|
|
|
|
Crystal structure analysis of human usp28 complex with a compound
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: usp28, kiaa1515. Expressed in: escherichia coli bl21(de3). Expression_system_taxid: 469008
|
|
|
Chain:
A
(320 residues)
|
|
|
|
|
|
The crystal structure of papain-like protease of sars cov-2, c111s/d286n mutant, in complex with a lys48-linked di-ubiquitin
|
|
|
Source: Severe acute respiratory syndrome coronavirus 2. Organism_taxid: 2697049. Expressed in: escherichia coli bl21(de3). Expression_system_taxid: 469008. Homo sapiens. Human. Organism_taxid: 9606. Gene: ubc.
|
|
|
Chains:
( residues)
|
|
|
|
|
|
Crystal structure of usp7-hubl domain
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: usp7, hausp. Expressed in: escherichia coli bl21(de3). Expression_system_taxid: 469008
|
|
|
Chain:
A
(529 residues)
|
|
|
|
|
|
Crystal structure of sars coronavirus main protease in complex with pf07321332
|
|
|
Source: Severe acute respiratory syndrome-related coronavirus. Organism_taxid: 694009. Gene: 1a. Expressed in: escherichia coli bl21(de3). Expression_system_taxid: 469008.
|
|
|
Chains:
A, B
(298 residues)
|
|
|
|
|
|
Crystal structure of mers main protease in complex with pf07321332
|
|
|
Source: Middle east respiratory syndrome-related coronavirus. Mers-cov. Organism_taxid: 1335626. Expressed in: escherichia coli bl21. Expression_system_taxid: 511693.
|
|
|
Chains:
A, B
(299 residues)
|
|
|
|
|
|
Usp34 catalytic domain
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: usp34, kiaa0570, kiaa0729. Expressed in: escherichia coli 'bl21-gold(de3)plyss ag'. Expression_system_taxid: 866768
|
|
|
Chains:
A, B
(340 residues)
|
|
|
|
|
|
Usp34 catalytic domain in complex with ubpa
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: usp34, kiaa0570, kiaa0729. Expressed in: escherichia coli 'bl21-gold(de3)plyss ag'. Expression_system_taxid: 866768. Gene: ubb. Expression_system_taxid: 866768
|
|
|
Chains:
A, B, C
(343 residues)
|
|
|
|
|
|
X-ray structure of hku1-plp2(cys109ser) catalytic mutant in complex with free ubiquitin
|
|
|
Source: Human coronavirus hku1. Organism_taxid: 290028. Gene: 1a. Expressed in: escherichia coli bl21(de3). Expression_system_taxid: 469008. Homo sapiens. Human. Organism_taxid: 9606. Gene: trees_t100014679.
|
|
|
Chain:
A
(309 residues)
|
|
|
|
|
|
Structure of pdcov mpro in complex with an inhibitor
|
|
|
Source: Porcine deltacoronavirus. Organism_taxid: 1586324. Gene: orf1ab. Expressed in: escherichia coli. Expression_system_taxid: 562. Synthetic: yes. Synthetic construct. Organism_taxid: 32630
|
|
|
Chains:
A, B, C, D, E, F
(304 residues)
|
|
|
|
|
|
Crystal structure of hcov-nl63 main protease with pf07304814
|
|
|
Source: Human coronavirus nl63. Organism_taxid: 277944. Gene: rep, 1a-1b. Expressed in: escherichia coli bl21. Expression_system_taxid: 511693.
|
|
|
Chains:
A, B
(299 residues)
|
|
|
|
|
|
Crystal structure of sars coronavirus main protease in complex with pf07304814
|
|
|
Source: Severe acute respiratory syndrome-related coronavirus. Organism_taxid: 694009. Gene: 1a. Expressed in: escherichia coli bl21(de3). Expression_system_taxid: 469008
|
|
|
Chains:
A, B
(299 residues)
|
|
|
|
|
|
Crystal structure of mers main protease in complex with pf07304814
|
|
|
Source: Middle east respiratory syndrome-related coronavirus. Organism_taxid: 1335626. Expressed in: escherichia coli bl21. Expression_system_taxid: 511693.
|
|
|
Chains:
A, B
(299 residues)
|
|
|
|
|
|
Crystal structure of sars coronavirus main protease in complex with baicalei
|
|
|
Source: Severe acute respiratory syndrome coronavirus 2. Organism_taxid: 694009. Expressed in: escherichia coli bl21(de3). Expression_system_taxid: 469008.
|
|
|
Chains:
A, B
(298 residues)
|
|
|
|
|
|
Crystal structure of the ntf2l domain of human g3bp1 in complex with the usp10 derived peptide
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: g3bp1, g3bp. Expressed in: escherichia coli. Expression_system_taxid: 562. Expression_system_taxid: 562
|
|
|
Chain:
C
(16 residues)
|
|
|
|
|
|
High-resolution x-ray cocrystal structure of usp7 in complex with x4
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: usp7, hausp. Expressed in: escherichia coli. Expression_system_taxid: 562
|
|
|
Chains:
A, B
(343 residues)
|
|
|
|
|
|
High-resolution x-ray cocrystal structure of usp7 in complex with lx04-46
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: usp7, hausp. Expressed in: escherichia coli. Expression_system_taxid: 562
|
|
|
Chain:
B
(334 residues)
|
|
|
|
|
|
Crystal structure of canine coronavirus main protease in complex with gc376
|
|
|
Source: Canine coronavirus. Organism_taxid: 11153. Expressed in: escherichia coli bl21(de3). Expression_system_taxid: 469008
|
|
|
Chains:
A, B, C, D, E, F, G, H
(299 residues)
|
|
|
|
|
|
Crystal structure of usp7 in complex with its inhibitor
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: usp7, hausp. Expressed in: escherichia coli bl21(de3). Expression_system_taxid: 469008.
|
|
|
Chain:
A
(528 residues)
|
|
|
|
|
|
Crystal structure of mers main protease in complex with inhibitor yh- 53
|
|
|
Source: Middle east respiratory syndrome-related coronavirus. Organism_taxid: 1335626. Gene: orf1ab. Expressed in: escherichia coli bl21. Expression_system_taxid: 511693.
|
|
|
Chains:
A, B
(299 residues)
|
|
|
|
|
|
Crystal structure of sars main protease in complex with inhibitor yh- 53
|
|
|
Source: Severe acute respiratory syndrome-related coronavirus. Organism_taxid: 694009. Gene: 1a. Expressed in: escherichia coli bl21(de3). Expression_system_taxid: 469008.
|
|
|
Chains:
A, B
(298 residues)
|
|
|
|
|
|
Crystal structure of hcov 229e main protease in complex with pf07321332
|
|
|
Source: Human coronavirus 229e. Organism_taxid: 11137. Gene: rep, 1a-1b. Expressed in: escherichia coli bl21(de3). Expression_system_taxid: 469008.
|
|
|
Chains:
A, B
(298 residues)
|
|
|
|
|
|
Crystal structure of human uchl3 in complex with farrerol
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: uchl3. Expressed in: escherichia phage ecszw-2. Expression_system_taxid: 2419741
|
|
|
Chain:
A
(202 residues)
|
|
|
|
|
|
Cryo-em structure of usp9x
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: usp9x, dffrx, fam, usp9. Expressed in: spodoptera frugiperda. Expression_system_taxid: 7108
|
|
|
Chains:
A, B, C
(1754 residues)
|
|
|
|
|
|
Cryo-em structure of usp9x, local refinement of monomer
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: usp9x, dffrx, fam, usp9. Expressed in: spodoptera frugiperda. Expression_system_taxid: 7108
|
|
|
Chain:
A
(1739 residues)
|
|
|
|
|
|
Usp1 bound to ubiquitin conjugated to fancd2 (focused refinement)
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: uba52, ubcep2. Expressed in: escherichia coli bl21(de3). Expression_system_taxid: 469008. Gene: usp1. Expressed in: spodoptera frugiperda. Expression_system_taxid: 7108.
|
|
|
Chain:
D
(330 residues)
|
|
|
|
|
|
Usp1 bound to ml323 and ubiquitin conjugated to fancd2 (focused refinement)
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: uba52, ubcep2. Expressed in: escherichia coli bl21(de3). Expression_system_taxid: 469008. Gene: usp1. Expressed in: spodoptera frugiperda. Expression_system_taxid: 7108.
|
|
|
Chain:
D
(285 residues)
|
|
|
|
|
|
Structure of uchl1 in complex with gk13s inhibitor
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: uchl1. Expressed in: escherichia coli. Expression_system_taxid: 562
|
|
|
Chains:
A, B, C, D, E, F, G, H, I, J
(213 residues)
|
|
|
|
|
|
Structure of the sars-cov-1 main protease in complex with ag7404
|
|
|
Source: Severe acute respiratory syndrome coronavirus. Organism_taxid: 2901879. Gene: 1a. Expressed in: escherichia coli. Expression_system_taxid: 562
|
|
|
Chain:
A
(302 residues)
|
|
|
|
|
|
Cryo-em structure of usp1-uaf1 bound to fanci and mono-ubiquitinated fancd2 without ml323 (consensus reconstruction)
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: fanci, kiaa1794. Expressed in: spodoptera frugiperda. Expression_system_taxid: 7108. Expression_system_cell_line: sf21. Gene: fancd2, facd. Gene: ubc.
|
|
|
Chain:
D
(330 residues)
|
|
|
|
|
|
Cryo-em structure of usp1-uaf1 bound to fanci and mono-ubiquitinated fancd2 with ml323 (consensus reconstruction)
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: fanci, kiaa1794. Expressed in: spodoptera frugiperda. Expression_system_taxid: 7108. Expression_system_cell_line: sf21. Gene: fancd2, facd. Gene: ubc.
|
|
|
Chain:
D
(285 residues)
|
|
|
|
|
|
Structure of usp36 in complex with fubi-pa
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: usp36, kiaa1453. Expressed in: escherichia coli. Expression_system_taxid: 562. Gene: fau. Expression_system_taxid: 562
|
|
|
Chain:
A
(324 residues)
|
|
|
|
|
|
Structure of usp36 in complex with ubiquitin-pa
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: usp36, kiaa1453. Expressed in: escherichia coli. Expression_system_taxid: 562. Gene: ubb. Expression_system_taxid: 562
|
|
|
Chains:
A, C
(324 residues)
|
|
|
|
|
|
Sars-cov nsp16-nsp10 complexed with n7-gtp
|
|
|
Source: Severe acute respiratory syndrome-related coronavirus. Organism_taxid: 694009. Gene: rep, 1a-1b. Expressed in: escherichia coli bl21(de3). Expression_system_taxid: 469008. Expression_system_taxid: 469008
|
|
|
Chains:
A, B
(289 residues)
|
|
|
|
|
|
Structure of usp54 in complex with lys63-linked diubiquitin-pa
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: usp54, c10orf29. Expressed in: escherichia coli. Expression_system_taxid: 562. Gene: ubb. Expression_system_taxid: 562
|
|
|
Chains:
A, D, G, J
(323 residues)
|
|
|
|
|
|
Sars-cov macro domain complexed with 3-(n-morpholino)propanesulfonic acid
|
|
|
Source: Severe acute respiratory syndrome coronavirus. Organism_taxid: 2901879. Gene: rep, 1a-1b. Expressed in: escherichia coli 'bl21-gold(de3)plyss ag'. Expression_system_taxid: 866768
|
|
|
Chains:
A, B, C
(173 residues)
|
|
|
|
|
|
Structure of the sars-cov2 plpro (c111s) in complex with a dimeric ubv that inhibits activity by an unusual allosteric mechanism
|
|
|
Source: Severe acute respiratory syndrome coronavirus 2. 2019-ncov, sars-cov-2. Organism_taxid: 2697049. Expressed in: escherichia coli. Expression_system_taxid: 562. Homo sapiens. Human. Organism_taxid: 9606.
|
|
|
Chains:
( residues)
|
|
|
|
|
|
Structure of mers 3cl protease in complex with the cyclopropane based inhibitor 15d
|
|
|
Source: Middle east respiratory syndrome-related coronavirus. Organism_taxid: 1335626. Gene: orf1a. Expressed in: escherichia coli bl21. Expression_system_taxid: 511693.
|
|
|
Chain:
A
(303 residues)
|
|
|
|
|
|
Structure of mers 3cl protease in complex with the cyclopropane based inhibitor 16d
|
|
|
Source: Middle east respiratory syndrome-related coronavirus. Organism_taxid: 1335626. Gene: orf1a. Expressed in: escherichia coli bl21. Expression_system_taxid: 511693.
|
|
|
Chain:
A
(303 residues)
|
|
|
|
|
|
Structure of mers 3cl protease in complex with the cyclopropane based inhibitor 17d
|
|
|
Source: Middle east respiratory syndrome-related coronavirus. Organism_taxid: 1335626. Gene: orf1a. Expressed in: escherichia coli bl21. Expression_system_taxid: 511693.
|
|
|
Chain:
A
(303 residues)
|
|
|
|
|
|
Crystal structure of human usp30 in complex with a covalent inhibitor 829 and a fab
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: usp30. Expressed in: escherichia coli. Expression_system_taxid: 562. Mus musculus. Organism_taxid: 10090. Expressed in: homo sapiens.
|
|
|
Chain:
A
(322 residues)
|
|
|
|
|
|
Crystal structure of human usp30 in complex with a covalent inhibitor 552 and a fab
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: usp30. Expressed in: escherichia coli. Expression_system_taxid: 562. Mus musculus. Organism_taxid: 10090. Expressed in: homo sapiens.
|
|
|
Chain:
A
(330 residues)
|
|
|
|
|
|
Crystal structure of usp7 in complex with allosteric inhibitor fx1- 3763
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: usp7, hausp. Expressed in: escherichia coli. Expression_system_taxid: 562
|
|
|
Chains:
A, B
(335 residues)
|
|
|
|
|
|
Structure of mers 3cl protease in complex with the cyclopropane based inhibitor 16d (high resolution)
|
|
|
Source: Middle east respiratory syndrome-related coronavirus. Organism_taxid: 1335626. Gene: orf1a. Expressed in: escherichia coli bl21. Expression_system_taxid: 511693.
|
|
|
Chain:
A
(302 residues)
|
|
|
|
|
|
Crystal structure of the r178q mutant of ubiquitin carboxy terminal hydrolase l1 (uch-l1)
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: uchl1. Expressed in: escherichia coli. Expression_system_taxid: 562
|
|
|
Chains:
A, B
(216 residues)
|
|
|
|
|
|
Crystal structure of mers 3cl protease in complex with a dimethyl sulfinyl benzene inhibitor
|
|
|
Source: Middle east respiratory syndrome-related coronavirus. Organism_taxid: 1335626. Gene: orf1a. Expressed in: escherichia coli. Expression_system_taxid: 562. Expression_system_cell: bl21(de3).
|
|
|
Chains:
A, B
(306 residues)
|
|
|
|
|
|
Crystal structure of mers 3cl protease in complex with a m- fluorophenyl dimethyl sulfane inhibitor
|
|
|
Source: Middle east respiratory syndrome-related coronavirus. Organism_taxid: 1335626. Gene: orf1a. Expressed in: escherichia coli. Expression_system_taxid: 562. Expression_system_cell: bl21(de3).
|
|
|
Chain:
A
(302 residues)
|
|
|
|
|
|
Crystal structure of mers 3cl protease in complex with a p- fluorophenyl dimethyl sulfane inhibitor
|
|
|
Source: Middle east respiratory syndrome-related coronavirus. Organism_taxid: 1335626. Gene: orf1a. Expressed in: escherichia coli. Expression_system_taxid: 562. Expression_system_cell: bl21(de3).
|
|
|
Chain:
A
(302 residues)
|
|
|
|
|
|
Crystal structure of mers 3cl protease in complex with a phenyl sulfane inhibitor
|
|
|
Source: Middle east respiratory syndrome-related coronavirus. Organism_taxid: 1335626. Gene: orf1a. Expressed in: escherichia coli. Expression_system_taxid: 562. Expression_system_cell: bl21(de3).
|
|
|
Chain:
A
(306 residues)
|
|
|
|
|
|
Crystal structure of porcine deltacoronavirus (hku-15) mpro with pfizer intravenous inhibitor pf-00835231
|
|
|
Source: Porcine deltacoronavirus. Organism_taxid: 1586324. Gene: orf1ab. Expressed in: escherichia coli. Expression_system_taxid: 562
|
|
|
Chains:
A, B
(301 residues)
|
|
|
|
|
|
Crystal structure of beluga whale gammacoronavirus sw1 mpro with gc- 376 captured in two conformational states
|
|
|
Source: Beluga whale coronavirus sw1. Organism_taxid: 694015. Expressed in: escherichia coli. Expression_system_taxid: 562
|
|
|
Chains:
A, B
(299 residues)
|
|
|
|
|
|
Crystal structure of middle east respiratory syndrome coronavirus (mers-cov) 3cl protease inactive mutant c148a
|
|
|
Source: Middle east respiratory syndrome-related coronavirus. Mers-cov. Organism_taxid: 1335626. Expressed in: escherichia coli. Expression_system_taxid: 562
|
|
|
Chains:
A, B, C, D
(306 residues)
|
|
|
|
|
|
Crystal structure of covalent inhibitor 2-chloro-n'-(n-(4- chlorophenyl)-n-methylglycyl)acetohydrazide bound to ubiquitin c- terminal hydrolase-l1
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: uchl1. Expressed in: escherichia coli. Expression_system_taxid: 562.
|
|
|
Chains:
A, B
(219 residues)
|
|
|
|
|
|
Prrsv-1 plp2 domain bound to ubiquitin
|
|
|
Source: Porcine reproductive and respiratory syndrome virus. Prrsv. Organism_taxid: 28344. Expressed in: escherichia coli. Expression_system_taxid: 562. Homo sapiens. Human. Organism_taxid: 9606.
|
|
|
Chains:
A, C, E
(164 residues)
|
|
|
|
|
|
Apo crystal structure of beluga whale gammacoronavirus sw1 mpro
|
|
|
Source: Beluga whale coronavirus sw1. Organism_taxid: 694015. Expressed in: escherichia coli. Expression_system_taxid: 562
|
|
|
Chains:
A, B
(302 residues)
|
|
|
|
|
|
Porcine epidemic diarrhea virus core polymerase complex
|
|
|
Source: Porcine epidemic diarrhea virus. Organism_taxid: 28295. Expressed in: spodoptera frugiperda. Expression_system_taxid: 7108. Gene: orf1a, 1b. Expressed in: escherichia coli bl21(de3). Expression_system_taxid: 469008. Gene: orf1. Synthetic: yes.
|
|
|
Chains:
A, B, C
(899 residues)
|
|
|
|
|
|
Cryo-em structure of bap1-asxl1 bound to chromatosome
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Expressed in: escherichia coli. Expression_system_taxid: 562. Gene: h2ac7, h2afg, hist1h2ad. Gene: hist2h2be, h2bfq. Gene: h1-4, h1f4, hist1h1e. Gene: bap1, kiaa0272, hucep-6.
|
|
|
Chain:
L
(301 residues)
|
|
|
|
|
|
Vismodegib binds to the catalytical domain of human ubiquitin-specific protease 28
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: usp28, kiaa1515. Expressed in: escherichia coli, escherichia. Expression_system_taxid: 562, 561
|
|
|
Chain:
A
(312 residues)
|
|
|
|
|
|
Crystal structure of sars main protease in complex with s217622
|
|
|
Source: Severe acute respiratory syndrome-related coronavirus. Sars-cov. Organism_taxid: 694009. Gene: 1a. Expressed in: escherichia coli bl21(de3). Expression_system_taxid: 469008
|
|
|
Chains:
A, B
(298 residues)
|
|
|
|
|
|
Crystal structure of mers main protease in complex with s217622
|
|
|
Source: Middle east respiratory syndrome-related coronavirus. Mers-cov. Organism_taxid: 1335626. Expressed in: escherichia coli bl21. Expression_system_taxid: 511693
|
|
|
Chains:
A, B
(299 residues)
|
|
|
|
|
|
Crystal structure of hcov-nl63 main protease with s217622
|
|
|
Source: Human coronavirus nl63. Hcov-nl63. Organism_taxid: 277944. Gene: rep, 1a-1b. Expressed in: escherichia coli bl21. Expression_system_taxid: 511693
|
|
|
Chains:
A, B
(296 residues)
|
|
|
|
|
|
Crystal structure of mers main protease in complex with gc376
|
|
|
Source: Middle east respiratory syndrome-related coronavirus. Organism_taxid: 1335626. Expressed in: escherichia coli bl21. Expression_system_taxid: 511693. Expression_system_cell_line: bl21
|
|
|
Chains:
A, B
(301 residues)
|
|
|
|
|
|
Crystal structure of hcov 229e main protease in complex with pf07304814
|
|
|
Source: Human coronavirus 229e. Organism_taxid: 11137. Gene: rep, 1a-1b. Expressed in: escherichia coli bl21(de3). Expression_system_taxid: 469008.
|
|
|
Chains:
A, B
(299 residues)
|
|
|
|
|
|
Crystal structure of usp47apo catalytic domain
|
|
|
Source: Caenorhabditis elegans. Organism_taxid: 6239. Gene: cele_t05h10.1, t05h10.1. Expressed in: escherichia coli. Expression_system_taxid: 562
|
|
|
Chains:
A, B, C
(350 residues)
|
|
|
|
|
|
Crystal structure of usp47 catalytic domain complex with ubiquitin
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: ubb. Expressed in: escherichia coli. Expression_system_taxid: 562. Caenorhabditis elegans. Organism_taxid: 6239. Gene: cele_t05h10.1, t05h10.1.
|
|
|
Chains:
D, B
(341 residues)
|
|
|
|
|
|
Crystal structure of mers main protease in complex with pf00835231
|
|
|
Source: Middle east respiratory syndrome-related coronavirus. Organism_taxid: 1335626. Gene: orf1a. Expressed in: escherichia coli bl21. Expression_system_taxid: 511693.
|
|
|
Chains:
A, B
(299 residues)
|
|
|
|
|
|
Crystal structure of ubiquitin specific protease 11 (usp11) in complex with a substrate mimetic
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: usp11, uhx1, frzs, mxan_4149. Expressed in: escherichia coli bl21(de3). Expression_system_taxid: 469008. Gene: ubb. Expression_system_taxid: 469008
|
|
|
Chains:
A, B
(470 residues)
|
|
|
|
|
|
Usp28 usp domain in complex with vismodegib
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: usp28, kiaa1515. Expressed in: escherichia coli. Expression_system_taxid: 562
|
|
|
Chain:
A
(331 residues)
|
|
|
|
|
|
Usp28 usp domain apo
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: usp28, kiaa1515. Expressed in: escherichia coli. Expression_system_taxid: 562
|
|
|
Chain:
A
(333 residues)
|
|
|
|
|
|
Usp28 in complex with az1
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: usp28, kiaa1515. Expressed in: escherichia coli. Expression_system_taxid: 562
|
|
|
Chains:
A, B
(444 residues)
|
|
|
|
|
|
Usp28 in complex with ft206
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: usp28, kiaa1515. Expressed in: escherichia coli. Expression_system_taxid: 562
|
|
|
Chains:
A, B
(439 residues)
|
|
|
|
|
|
Bat-hp-cov nsp1 and eif1 bound to the human 40s small ribosomal subunit
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: eif1, sui1. Expressed in: escherichia coli. Expression_system_taxid: 562. Cell_line: hek293e. Cell_line: hek293. Bat hp-betacoronavirus/zhejiang2013.
|
|
|
Chain:
j
(174 residues)
|
|
|
|
|
|
Structure of human uchl1 in complex with cg341 inhibitor
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: uchl1. Expressed in: escherichia coli. Expression_system_taxid: 562
|
|
|
Chains:
A, B, C, D, E, F, G, H, I, J
(223 residues)
|
|
|
|
|
|
Ef-hand of mindy3 deubiquitylase in complex with ubl of rad23a
|
|
|
Source: Escherichia coli. Organism_taxid: 562. Gene: mda_glean10008107. Expressed in: escherichia coli. Expression_system_taxid: 562. Gene: rad23a. Expression_system_taxid: 562
|
|
|
Chains:
A, B
(69 residues)
|
|
|
|
|
|
Cryo-em structure of pre-b+5'ss+atpgammas complex (core part)
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Organism_taxid: 9606
|
|
|
Chain:
U
(456 residues)
|
|
|
|
|
|
Cryo-em structure of pre-b complex (core part)
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Organism_taxid: 9606
|
|
|
Chain:
U
(456 residues)
|
|
|
|
|
|
Cryo-em structure of pre-b+amppnp complex (core part)
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Organism_taxid: 9606
|
|
|
Chain:
U
(456 residues)
|
|
|
|
|
|
Cryo-em structure of pre-b+5'sslng complex (core part)
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Organism_taxid: 9606
|
|
|
Chain:
U
(456 residues)
|
|
|
|
|
|
Cryo-em structure of pre-b+atp complex (core part)
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Organism_taxid: 9606
|
|
|
Chain:
U
(456 residues)
|
|
|
|
|
|
Cryo-em structure of pre-b+5'ss complex (core part)
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Organism_taxid: 9606
|
|
|
Chain:
U
(456 residues)
|
|
|
|
|
|
Crystal structure of mers-cov main protease
|
|
|
Source: Middle east respiratory syndrome-related coronavirus. Organism_taxid: 1335626. Gene: 1a. Expressed in: escherichia coli bl21. Expression_system_taxid: 511693
|
|
|
Chains:
A, B
(303 residues)
|
|
|
|
|
|
Structure of human eif3 core from closed 48s translation initiation complex
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Expressed in: escherichia coli. Expression_system_taxid: 562. Organism_taxid: 9606
|
|
|
Chain:
4
(257 residues)
|
|
|
|
|
|
Bap1/asxl1 bound to the h2ak119ub nucleosome
|
|
|
Source: Xenopus laevis. African clawed frog. Organism_taxid: 8355. Expressed in: escherichia coli. Expression_system_taxid: 562. Synthetic: yes. Synthetic construct. Organism_taxid: 32630. Homo sapiens.
|
|
|
Chain:
K
(278 residues)
|
|
|
|
|
|
Mers-cov nsp1 protein bound to the human 40s ribosomal subunit
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Middle east respiratory syndrome-related coronavirus. Organism_taxid: 1335626. Expressed in: escherichia coli. Expression_system_taxid: 562
|
|
|
Chain:
n
(25 residues)
|
|
|
|
|
|
Human cytomegalovirus portal vertex, virion configuration 2 (vc2)
|
|
|
Source: Human herpesvirus 5 strain ad169. Organism_taxid: 10360. Organism_taxid: 10360
|
|
|
Chains:
A, C
(40 residues)
|
|
|
|
|
|
Human cytomegalovirus portal vertex, non-infectious enveloped particle (niep) configuration 1 (nc1)
|
|
|
Source: Human herpesvirus 5 strain ad169. Organism_taxid: 10360. Organism_taxid: 10360
|
|
|
Chains:
A, C
(41 residues)
|
|
|
|
|
|
Human cytomegalovirus portal vertex, non-infectious enveloped particle (niep) configuration 2 - inverted (nc2-inv)
|
|
|
Source: Human herpesvirus 5 strain ad169. Organism_taxid: 10360. Organism_taxid: 10360
|
|
|
Chains:
A, C
(722 residues)
|
|
|
|
|
|
Crystal structure of the g3bp1 ntf2-like domain bound to usp10 peptide
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: g3bp1, g3bp. Expressed in: escherichia coli. Expression_system_taxid: 562. Gene: usp10, kiaa0190. Expression_system_taxid: 562
|
|
|
Chains:
E, F, G, H
(18 residues)
|
|
|
|
|
|
Crystal structure of sars-unique domain (sud) of nsp3 from sars coronavirus
|
|
|
Source: Severe acute respiratory syndrome coronavirus. Organism_taxid: 2901879. Gene: 1a. Expressed in: escherichia coli bl21(de3). Expression_system_taxid: 469008. Expression_system_variant: magic.
|
|
|
Chains:
A, B
(263 residues)
|
|
|
|
|
|
Crystal structure of l516c/y647c mutant of sars-unique domain (sud) from sars-cov-2
|
|
|
Source: Severe acute respiratory syndrome coronavirus 2. Organism_taxid: 2697049. Expressed in: escherichia coli bl21(de3). Expression_system_taxid: 469008. Expression_system_variant: magic.
|
|
|
Chain:
A
(249 residues)
|
|
|
|
|
|
Sara cov-2 3c-like protease in complex with gsk3487016a
|
|
|
Source: Severe acute respiratory syndrome coronavirus. Organism_taxid: 2901879. Gene: 1a. Expressed in: escherichia coli. Expression_system_taxid: 562
|
|
|
Chain:
A
(305 residues)
|
|
|
|
|
|
Porcine epidemic diarrhea virus complete core polymerase complex
|
|
|
Source: Porcine epidemic diarrhea virus. Organism_taxid: 28295. Gene: 1b, orf1a. Expressed in: spodoptera frugiperda. Expression_system_taxid: 7108. Expressed in: escherichia coli bl21(de3). Expression_system_taxid: 469008. Synthetic: yes. Synthetic construct.
|
|
|
Chains:
A, B, C, D
(921 residues)
|
|
|
|
|
|
Cryo-em structure of usp16 bound to h2ak119ub nucleosome
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: usp16, mstp039. Expressed in: escherichia coli. Expression_system_taxid: 562. Gene: h3c1, h3fa, hist1h3a, h3c2, h3fl, hist1h3b, h3c3, h3fc hist1h3c, h3c4, h3fb, hist1h3d, h3c6, h3fd, hist1h3e, h3c7, h3fi, hist1h3f, h3c8, h3fh, hist1h3g, h3c10, h3fk, hist1h3h, h3c11, h3ff,
|
|
|
Chain:
M
(298 residues)
|
|
|
|
|
|
Portal vertex capsomer of the vzv c-capsid
|
|
|
Source: Human alphaherpesvirus 3. Varicella-zoster virus. Organism_taxid: 10335. Gene: mcp, 40. Expressed in: homo sapiens. Expression_system_taxid: 9606. Gene: cvc2, ul25. Gene: ul36. Expression_system_taxid: 9606
|
|
|
Chains:
n, o
(47 residues)
|
|
|
|
|
|
P-hexon capsomer of the vzv c-capsid
|
|
|
Source: Human alphaherpesvirus 3. Varicella-zoster virus. Organism_taxid: 10335. Gene: mcp, 40. Expressed in: homo sapiens. Expression_system_taxid: 9606. Gene: scp. Gene: cvc2, ul25. Gene: ul36.
|
|
|
Chains:
n, o
(47 residues)
|
|
|
|
|
|
Penton capsomer of the vzv c-capsid
|
|
|
Source: Human alphaherpesvirus 3. Varicella-zoster virus. Organism_taxid: 10335. Gene: ul36. Expressed in: homo sapiens. Expression_system_taxid: 9606. Gene: orf40, mcp, orf 40, hhv3_e_svetagp42, hhv3_gp42, hhv3gp42. Gene: cvc1, ul17. Gene: cvc2, ul25.
|
|
|
Chains:
2, y
(47 residues)
|
|
|
|
|
|
The crystal structure of uchl1 from biortus.
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: uchl1. Expressed in: escherichia coli. Expression_system_taxid: 562
|
|
|
Chains:
A, B
(222 residues)
|
|
|
|
|
|
Structure of thE C-terminal domain of nsp4 from pedv
|
|
|
Source: Porcine epidemic diarrhea virus. Organism_taxid: 28295. Expressed in: escherichia coli. Expression_system_taxid: 562
|
|
|
Chain:
A
(90 residues)
|
|
|
|
|
|
The crystal structure of usp8 from biortus.
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: usp8, kiaa0055, ubpy. Expressed in: escherichia coli. Expression_system_taxid: 562
|
|
|
Chains:
A, B, C
(341 residues)
|
|
|
|
|
|
Crystal structure of sars main protease in complex with bofutrelvir
|
|
|
Source: Severe acute respiratory syndrome-related coronavirus. Sars-cov. Organism_taxid: 694009. Gene: 1a. Expressed in: escherichia coli bl21(de3). Expression_system_taxid: 469008
|
|
|
Chains:
A, B
(298 residues)
|
|
|
|
|
|
Crystal structure of hcov 229e main protease in complex with bofutrelvir
|
|
|
Source: Human coronavirus 229e. Hcov-229e. Organism_taxid: 11137. Gene: rep, 1a-1b. Expressed in: escherichia coli bl21(de3). Expression_system_taxid: 469008
|
|
|
Chains:
A, B
(298 residues)
|
|
|
|
|
|
The crystal structure of usp8 from biortus.
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: usp8, kiaa0055, ubpy. Expressed in: escherichia coli. Expression_system_taxid: 562
|
|
|
Chain:
A
(127 residues)
|
|
|
|
|
|
Cryo-em structure of p97-vcpip1 complex
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: vcp, hel-220, hel-s-70. Expressed in: escherichia coli bl21(de3). Expression_system_taxid: 469008. Gene: vcpip1, kiaa1850, vcip135. Expression_system_taxid: 469008
|
|
|
Chains:
2, 3, 1
(569 residues)
|
|
|
|
|
|
Crystal structure of sars main protease in complex with x77
|
|
|
Source: Severe acute respiratory syndrome-related coronavirus. Organism_taxid: 694009. Gene: rep, 1a-1b. Expressed in: escherichia coli bl21(de3). Expression_system_taxid: 469008.
|
|
|
Chain:
A
(298 residues)
|
|
|
|
|
|
Crystal structure of mers main protease in complex with x77
|
|
|
Source: Middle east respiratory syndrome-related coronavirus. Organism_taxid: 1335626. Expressed in: escherichia coli bl21. Expression_system_taxid: 511693.
|
|
|
Chains:
A, B
(299 residues)
|
|
|
|
|
|
Crystal structure of hcov-nl63 main protease with x77
|
|
|
Source: Human coronavirus nl63. Organism_taxid: 277944. Gene: rep, 1a-1b. Expressed in: escherichia coli bl21. Expression_system_taxid: 511693
|
|
|
Chains:
A, B
(298 residues)
|
|
|
|
|
|
Structure of thE C-terminal domain of nsp4 from pdcov
|
|
|
Source: Porcine deltacoronavirus. Organism_taxid: 1586324. Expressed in: escherichia coli. Expression_system_taxid: 562
|
|
|
Chains:
B, A
(81 residues)
|
|
|
|
|
|
Sars-cov-2 papain-like protease (plpro) c111s untagged crystal structure
|
|
|
Source: Severe acute respiratory syndrome coronavirus 2. 2019-ncov, sars-cov-2. Organism_taxid: 2697049. Gene: rep, 1a-1b. Expressed in: escherichia coli. Expression_system_taxid: 562
|
|
|
Chains:
( residues)
|
|
|
|
|
|
Crystal structure of mers-cov nsp5 in complex with pf-07817883
|
|
|
Source: Middle east respiratory syndrome-related coronavirus. Organism_taxid: 1335626. Gene: 1a. Expressed in: escherichia coli bl21(de3). Expression_system_taxid: 469008
|
|
|
Chain:
A
(304 residues)
|
|
|
|
|
|
Yeast 26s proteasome non-substrate-engaged (s1 state)
|
|
|
Source: Saccharomyces cerevisiae. Brewer's yeast. Organism_taxid: 4932. Organism_taxid: 4932
|
|
|
Chain:
V
(288 residues)
|
|
|
|
|
|
Infectious bronchitis virus core polymerase complex
|
|
|
Source: Infectious bronchitis virus. Organism_taxid: 11120. Gene: rep, 1a-1b. Expressed in: escherichia coli bl21. Expression_system_taxid: 511693. Synthetic: yes. Severe acute respiratory syndrome coronavirus 2. Organism_taxid: 2697049.
|
|
|
Chains:
A, B, C, D
(930 residues)
|
|
|
|
|
|
Turnip yellow mosaic virus (tymv) protease (pro) bound to a ubiquitin variant (ubv3)
|
|
|
Source: Turnip yellow mosaic virus. Organism_taxid: 12154. Expressed in: escherichia coli. Expression_system_taxid: 562. Synthetic construct. Organism_taxid: 32630. Expression_system_taxid: 562
|
|
|
Chains:
A, C
(145 residues)
|
|
|
|
|
|
Usp7 in complex with macrocycle inhibitor mc02
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: usp7, hausp. Expressed in: escherichia coli. Expression_system_taxid: 562. Synthetic: yes. Synthetic construct. Organism_taxid: 32630
|
|
|
Chains:
A, B
(333 residues)
|
|
|
|
|
|
Usp7 in complex with macrocycle mc03
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: usp7, hausp. Expressed in: escherichia coli. Expression_system_taxid: 562. Synthetic: yes. Synthetic construct. Organism_taxid: 32630
|
|
|
Chains:
A, B
(331 residues)
|
|
|
|
|
|
Usp7 in complex with macrocycle mc04
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: usp7, hausp. Expressed in: escherichia coli. Expression_system_taxid: 562. Synthetic: yes. Synthetic construct. Organism_taxid: 32630
|
|
|
Chain:
A
(330 residues)
|
|
|
|
|
|
Usp7 in complex with macrocycle mc07
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: usp7, hausp. Expressed in: escherichia coli. Expression_system_taxid: 562. Synthetic: yes. Synthetic construct. Organism_taxid: 32630
|
|
|
Chains:
B, A
(333 residues)
|
|
|
|
|
|
Usp7 in complex with macrocycle inhibitor mc08
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: usp7, hausp. Expressed in: escherichia coli. Expression_system_taxid: 562. Synthetic: yes. Synthetic construct. Organism_taxid: 32630
|
|
|
Chains:
A, B
(335 residues)
|
|
|
|
|
|
Usp7 in complex with macrocycle mc09
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: usp7, hausp. Expressed in: escherichia coli. Expression_system_taxid: 562. Synthetic: yes. Synthetic construct. Organism_taxid: 32630
|
|
|
Chains:
A, B, E
(334 residues)
|
|
|
|
|
|
Cryo-em structure of vcp/p97 in complex with vcpip1 (vcip135)
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: vcp. Expressed in: escherichia coli. Expression_system_taxid: 562. Gene: vcpip1, kiaa1850, vcip135. Expression_system_taxid: 562
|
|
|
Chain:
C
(111 residues)
|
|
|
|
|
|
Crystal structure of the uch37 rpn13 deubad complex bound to an inhibitory nanobody in the canonical ubiquitin binding site
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: uchl5, uch37, ad-019, cgi-70. Expressed in: escherichia coli. Expression_system_taxid: 562. Camelidae mixed library. Organism_taxid: 1579311. Gene: adrm1, gp110.
|
|
|
Chain:
A
(278 residues)
|
|
|
|
|
|
Seneca valley virus altered particle at acidic condition (a- particle[c])
|
|
|
Source: Seneca valley virus usa/ssv-001. Organism_taxid: 686944. Organism_taxid: 686944
|
|
|
Chains:
A, B, C, D
(258 residues)
|
|
|
|
|
|
Seneca valley virus altered particle at physiological condition (a- particle[p])
|
|
|
Source: Seneca valley virus usa/ssv-001. Organism_taxid: 686944. Organism_taxid: 686944
|
|
|
Chains:
A, B, C, D
(255 residues)
|
|
|
|
|
|
Seneca valley virus empty rotated particle at acidic condition (er- particle[c])
|
|
|
Source: Seneca valley virus usa/ssv-001. Organism_taxid: 686944. Organism_taxid: 686944
|
|
|
Chains:
A, B, C
(230 residues)
|
|
|
|
|
|
Seneca valley virus empty rotated particle at physiological condition (er-particle[p])
|
|
|
Source: Seneca valley virus usa/ssv-001. Organism_taxid: 686944. Organism_taxid: 686944
|
|
|
Chains:
A, B, C
(231 residues)
|
|
|
|
|
|
Human usp30 chimera bound to ubiquitin-pa
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: usp30, usp14, tgt, usp35, kiaa1372, usp34. Expressed in: escherichia coli. Expression_system_taxid: 562. Gene: ubb. Expression_system_taxid: 562
|
|
|
Chain:
A
(281 residues)
|
|
|
|
|
|
Usp1 bound to ml323 and ubiquitin conjugated to fancd2 (ordered subset, focused refinement)
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: ubc. Expressed in: escherichia coli bl21(de3). Expression_system_taxid: 469008. Gene: usp1. Expressed in: spodoptera frugiperda. Expression_system_taxid: 7108.
|
|
|
Chain:
D
(312 residues)
|
|
|
|
|
|
Structure-guided discovery of selective usp7 inhibitors with in vivo activity
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: usp7, hausp. Expressed in: escherichia coli o111:nm str. 01-3076. Expression_system_taxid: 1446512. Expression_system_variant: plyss.
|
|
|
Chains:
A, B
(332 residues)
|
|
|
|
|
|
A rare open conformation for ubl2 domain of papain-like protease of sars-cov2
|
|
|
Source: Severe acute respiratory syndrome coronavirus 2. Organism_taxid: 2697049. Expressed in: escherichia coli. Expression_system_taxid: 562.
|
|
|
Chains:
( residues)
|
|
|
|
|
|
A rare open conformation for ubl2 domain of papain-like protease c111s of sars-cov2
|
|
|
Source: Severe acute respiratory syndrome coronavirus 2. Organism_taxid: 2697049. Expressed in: escherichia coli. Expression_system_taxid: 562.
|
|
|
Chains:
( residues)
|
|
|
|
|
|
A rare open conformation for ubl2 domain of papain-like protease without zinc of sars-cov2
|
|
|
Source: Severe acute respiratory syndrome coronavirus 2. Organism_taxid: 2697049. Expressed in: escherichia coli. Expression_system_taxid: 562.
|
|
|
Chains:
( residues)
|
|
|
|
|
|
Usp1-uaf1 bound to lys63-linked diubiquitin
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: usp1. Expressed in: spodoptera frugiperda. Expression_system_taxid: 7108. Gene: wdr48, kiaa1449, uaf1. Synthetic: yes. Organism_taxid: 9606
|
|
|
Chain:
A
(406 residues)
|
|
|
|
|
|
Deubiquitinase dub16 from leishmania donovani
|
|
|
Source: Leishmania donovani. Organism_taxid: 5661. Gene: cgc20_27140, cgc21_8200, ldbpk_250190, ldhu3_25.0250. Expressed in: escherichia coli bl21. Expression_system_taxid: 511693
|
|
|
Chains:
A, B
(219 residues)
|
|
|
|
|
|
Sertraline enhances the deubiquitinase activity of usp7 by binding to its switching loop region
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: usp7, hausp. Expressed in: escherichia coli. Expression_system_taxid: 562. Gene: rps27a, uba80, ubcep1. Expression_system_taxid: 562
|
|
|
Chains:
A, C, E, G
(326 residues)
|
|
|
|
|
|
Sertraline enhances the deubiquitinase activity of usp7 by binding to its switching loop region
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: usp7, hausp. Expressed in: escherichia coli. Expression_system_taxid: 562. Gene: rps27a, uba80, ubcep1. Expression_system_taxid: 562
|
|
|
Chains:
A, C, E, G
(320 residues)
|
|
|
|
|
|
Crystal structure of mers main protease in complex with bofutrelvir
|
|
|
Source: Middle east respiratory syndrome-related coronavirus. Organism_taxid: 1335626. Gene: rep, 1a-1b. Expressed in: escherichia coli bl21. Expression_system_taxid: 511693
|
|
|
Chains:
A, B, C, D
(301 residues)
|
|
|
|
|
|
Crystal structure of mers main protease in complex with carmofur
|
|
|
Source: Middle east respiratory syndrome-related coronavirus. Organism_taxid: 1335626. Expressed in: escherichia coli bl21. Expression_system_taxid: 511693
|
|
|
Chains:
A, B
(300 residues)
|
|
|
|
|
|
Pedv 3clpro mutant (c144a) in complex with nsp9|10 peptidyl substrate
|
|
|
Source: Porcine epidemic diarrhea virus. Organism_taxid: 28295. Expressed in: escherichia coli. Expression_system_taxid: 562. Synthetic: yes. Organism_taxid: 28295
|
|
|
Chains:
A, B
(298 residues)
|
|
|
|
|
|
Cryo-em structure of usp7:dnmt1 complex; closed conformation
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: usp7, hausp. Expressed in: escherichia coli. Expression_system_taxid: 562. Gene: dnmt1, aim, cxxc9, dnmt. Expressed in: spodoptera frugiperda. Expression_system_taxid: 7108
|
|
|
Chain:
A
(524 residues)
|
|
|
|
|
|
Cryo-em structure of usp7:dnmt1 complex; open conformation
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: usp7, hausp. Expressed in: escherichia coli. Expression_system_taxid: 562. Gene: dnmt1, aim, cxxc9, dnmt. Expressed in: spodoptera frugiperda. Expression_system_taxid: 7108
|
|
|
Chain:
A
(524 residues)
|
|
|
|
|
|
Bat mersr-cov neocov nsp1 bound to the human 40s ribosomal subunit- state1
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Expressed in: homo sapiens. Expression_system_taxid: 9606. Gene: rpsa, lambr, lamr1. Gene: rps3a, fte1, mftl. Gene: rps2, rps4. Gene: rps3, ok/sw-cl.26.
|
|
|
Chain:
n
(26 residues)
|
|
|
|
|
|
Bat mersr-cov neocov nsp1 bound to the human 40s ribosomal subunit- state2
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Expressed in: homo sapiens. Expression_system_taxid: 9606. Gene: rpsa, lambr, lamr1. Gene: rps3a, fte1, mftl. Gene: rps2, rps4. Gene: rps3, ok/sw-cl.26.
|
|
|
Chain:
n
(26 residues)
|
|
|
|
|
|
Bat mersr-cov nl140422 nsp1 bound to the human 40s ribosomal subunit- state1
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Expressed in: homo sapiens. Expression_system_taxid: 9606. Gene: rpsa, lambr, lamr1. Gene: rps3a, fte1, mftl. Gene: rps2, rps4. Gene: rps3, ok/sw-cl.26.
|
|
|
Chain:
n
(27 residues)
|
|
|
|
|
|
Bat mersr-cov nl140422 nsp1 bound to the human 40s ribosomal subunit- state2
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Expressed in: homo sapiens. Expression_system_taxid: 9606. Gene: rpsa, lambr, lamr1. Gene: rps3a, fte1, mftl. Gene: rps2, rps4. Gene: rps3, ok/sw-cl.26.
|
|
|
Chain:
n
(27 residues)
|
|
|
|
|
|
Cryo-em structure of three vcpip1 vcpids bound to vcp
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: vcpip1, kiaa1850, vcip135. Expressed in: homo sapiens. Expression_system_taxid: 9606. Expression_system_cell: expi293. Gene: vcp, hel-220, hel-s-70. Expression_system_cell: expi293
|
|
|
Chains:
G, H, I
(65 residues)
|
|
|
|
|
|
Cryo-em structure of vcpip1 vcpid bound to vcp d2 domain dimer (with extra d2 domain)
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: vcpip1, kiaa1850, vcip135. Expressed in: homo sapiens. Expression_system_taxid: 9606. Expression_system_cell: expi293. Gene: vcp, hel-220, hel-s-70. Expression_system_cell: expi293
|
|
|
Chain:
D
(126 residues)
|
|
|
|
|
|
Cryo-em structure of vcpip1 ubx domain bound to vcp n-domain (with d1 domain)
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: vcpip1, kiaa1850, vcip135. Expressed in: homo sapiens. Expression_system_taxid: 9606. Expression_system_cell: expi293. Gene: vcp, hel-220, hel-s-70. Expression_system_cell: expi 293
|
|
|
Chain:
B
(79 residues)
|
|
|
|
|
|
Cryo-em structure of three vcpip1 vcpids bound to vcp
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: vcpip1, kiaa1850, vcip135. Expressed in: homo sapiens. Expression_system_taxid: 9606. Expression_system_cell: expi293. Gene: vcp, hel-220, hel-s-70. Expression_system_cell: expi293
|
|
|
Chains:
G, H, I
(94 residues)
|
|
|
|
|
|
Cryo-em structure of vcp/p97 and vcpip1 (vcip135) in the presence of amppnp
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: vcp. Expressed in: escherichia coli. Expression_system_taxid: 562. Gene: vcpip1, kiaa1850, vcip135. Expression_system_taxid: 562
|
|
|
Chain:
C
(112 residues)
|
|
|
|
|
|
Co-crystal structure of feline coronavirus uu23 main protease with nirmatrelvir
|
|
|
Source: Feline coronavirus uu23. Organism_taxid: 711466. Expressed in: escherichia coli. Expression_system_taxid: 562
|
|
|
Chains:
A, B, C, D
(298 residues)
|
|
|
|
|
|
Co-crystal structure of feline coronavirus uu23 main protease with gc376
|
|
|
Source: Feline coronavirus uu23. Organism_taxid: 711466. Expressed in: escherichia coli. Expression_system_taxid: 562
|
|
|
Chain:
A
(300 residues)
|
|
|
|
|
|
Co-crystal structure of feline coronavirus uu23 main protease with pfizer intravenous compound pf-00835231
|
|
|
Source: Feline alphacoronavirus 1. Organism_taxid: 2421386. Expressed in: escherichia coli. Expression_system_taxid: 562
|
|
|
Chain:
A
(300 residues)
|
|
|
|
|
|
Usp21 bound to h2ak119ub nucleosome
|
|
|
Source: Xenopus laevis. African clawed frog. Organism_taxid: 8355. Expressed in: escherichia coli. Expression_system_taxid: 562. Synthetic construct. Organism_taxid: 32630. Homo sapiens. Human.
|
|
|
Chain:
K
(283 residues)
|
|
|
|
|
|
Crystal structure of ubiquitin carboxy terminal hydrolase l1 q209c mutant covalently crosslinked to ubiquitin genetically encoded with n6-(6-bromohexanoyl)-l-lysine
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: ubc. Expressed in: escherichia coli. Expression_system_taxid: 562. Gene: uchl1. Expression_system_taxid: 562
|
|
|
Chains:
A, B
(216 residues)
|
|
|
|
|
|
Co-crystal structure of feline coronavirus uu23 main protease with ibuzatrelvir
|
|
|
Source: Feline coronavirus uu23. Organism_taxid: 711466. Expressed in: escherichia coli 'bl21-gold(de3)plyss ag'. Expression_system_taxid: 866768
|
|
|
Chains:
A, B, C, D
(302 residues)
|
|
|
|
|
|
Crystal structure of c270s mutant of papain-like protease (plpro) from sars-cov-2
|
|
|
Source: Severe acute respiratory syndrome coronavirus 2. Organism_taxid: 2697049. Gene: rep, 1a-1b. Expressed in: escherichia coli. Expression_system_taxid: 562
|
|
|
Chains:
( residues)
|
|
|
|
|
|
Crystal structure of usp49 znf-ubp domain
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: usp49. Expressed in: escherichia coli bl21. Expression_system_taxid: 511693.
|
|
|
Chain:
A
(105 residues)
|
|
|
[IntEnz]
[ExPASy]
[KEGG]
