PDBsum entry 1v0z

Hydrolase

PDB id: 1v0z

Contents

Protein chains

389 a.a. *

Ligands

NAG-NAG ×2

NAG-BMA-MAN-MAN

NAG-NAG-BMA-MAN-MAN-MAN

NAG-BMA-MAN

BMA-MAN

GOL ×4

NAG ×12

MAN ×7

PEG

Metals

_CA ×4

Waters ×1798

* Residue conservation analysis

PDB id:

1v0z

Name:

Hydrolase

Title:

Structure of neuraminidase from english duck subtype n6

Structure:

Neuraminidase. Chain: a, b, c, d. Engineered: yes

Source:

Influenza a virus. Organism_taxid: 11320. Expressed in: gallus gallus. Expression_system_taxid: 9031

Resolution:

1.84Å R-factor: 0.151 R-free: 0.190

Authors:

E.Rudino-Pinera,P.Tunnah,S.J.Crennell,R.G.Webster,W.G.Laver, E.F.Garman

Key ref:

E.Rudino-Pinera et al. The crystal structure of influenza type a virus neuraminidase of the n6 subtype at 1.85 a resolution. To be published, .

Date:

02-Apr-04 Release date: 25-Jan-06

Protein chains

Q6XV27  (NRAM_I56A2) -  Neuraminidase from Influenza A virus (strain A/Duck/England/1/1956 H11N6)

Seq: 470 a.a.

Struc: 389 a.a.

Enzyme reactions

• Enzyme class: E.C.3.2.1.18 - exo-alpha-sialidase.
• Reaction: Hydrolysis of alpha-(2->3)-, alpha-(2->6)-, alpha-(2->8)-glycosidic linkages of terminal sialic residues in oligosaccharides, glycoproteins, glycolipids, colominic acid and synthetic substrates.