PDBsum entry 1k4f

Hydrolase

PDB id: 1k4f

Contents

Protein chains

244 a.a. *

Ligands

SO4 ×4

Waters ×626

* Residue conservation analysis

PDB id:

1k4f

Name:

Hydrolase

Title:

Crystal structure of the class d beta-lactamase oxa-10 at 1.6 a resolution

Structure:

Beta-lactamase pse-2. Chain: a, b. Synonym: beta lactamase oxa-10. Engineered: yes

Source:

Pseudomonas aeruginosa. Organism_taxid: 287. Gene: plasmid pmon234. Expressed in: escherichia coli bl21(de3). Expression_system_taxid: 469008.

Biol. unit:

Dimer (from PQS)

Resolution:

1.60Å R-factor: 0.189 R-free: 0.228

Authors:

F.Kerff,E.Fonze,F.Bouillene,J.M.Frere,P.Charlier

Key ref:

F.Kerff et al. Structure of the class d beta-Lactamase oxa-2. To be published, .

Date:

08-Oct-01 Release date: 31-Oct-01

Protein chains

P14489  (BLO10_PSEAI) -  Beta-lactamase OXA-10 from Pseudomonas aeruginosa

Seq: 266 a.a.

Struc: 244 a.a.*

* PDB and UniProt seqs differ at 1 residue position (black cross)

Enzyme reactions

• Enzyme class: E.C.3.5.2.6 - beta-lactamase.
• Pathway: Penicillin Biosynthesis and Metabolism
• Reaction: a beta-lactam + H2O = a substituted beta-amino acid
• Cofactor: Zn(2+)