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PDBsum entry 1pvc
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279 a.a.
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266 a.a.
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235 a.a.
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62 a.a.
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* Residue conservation analysis
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PDB id:
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Virus
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Title:
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Refinement of the sabin strain of type 3 poliovirus at 2.4 angstroms and the crystal structures of its variants at 2.9 angstroms resolution
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Structure:
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Poliovirus type 3, sabin strain. Chain: 0. Other_details: p3/sabin p3/leon/12a(1)b. Poliovirus type 3, sabin strain. Chain: 1. Other_details: p3/sabin p3/leon/12a(1)b. Poliovirus type 3, sabin strain. Chain: 2. Other_details: p3/sabin p3/leon/12a(1)b.
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Source:
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Poliovirus type 3 (strains p3/leon/37 and p3/leon 12a[1]b). Organism_taxid: 12088. Strain: derived from laboratory strain p3/leon/12a(1)b placque 411. Other_details: seed stock obtained from p.D.Minor (national institute of biological standards and control, london). Institute of biological standards and control, london)
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Resolution:
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Authors:
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R.Syed,D.J.Filman,J.M.Hogle
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Key ref:
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R.Syed
et al.
Refinement of the sabin strain of type 3 poliovirus at 2.4 angstroms and the crystal structures of its variants at 2.9 angstroms resolution.
To be published,
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Date:
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30-Mar-95
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Release date:
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15-Sep-95
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PROCHECK
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Headers
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References
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P03302
(POLG_POL3L) -
Genome polyprotein from Poliovirus type 3 (strains P3/Leon/37 and P3/Leon 12A[1]B)
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Seq:
Struc:
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2206 a.a.
279 a.a.*
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P03302
(POLG_POL3L) -
Genome polyprotein from Poliovirus type 3 (strains P3/Leon/37 and P3/Leon 12A[1]B)
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Seq:
Struc:
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2206 a.a.
266 a.a.
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Enzyme class 2:
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Chains 1, 2, 3, 4:
E.C.2.7.7.48
- RNA-directed Rna polymerase.
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Reaction:
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RNA(n) + a ribonucleoside 5'-triphosphate = RNA(n+1) + diphosphate
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RNA(n)
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+
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ribonucleoside 5'-triphosphate
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=
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RNA(n+1)
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+
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diphosphate
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Enzyme class 3:
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Chains 1, 2, 3, 4:
E.C.3.4.22.28
- picornain 3C.
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Reaction:
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Selective cleavage of Gln-|-Gly bond in the poliovirus polyprotein. In other picornavirus reactions Glu may be substituted for Gln, and Ser or Thr for Gly.
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Enzyme class 4:
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Chains 1, 2, 3, 4:
E.C.3.4.22.29
- picornain 2A.
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Reaction:
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Selective cleavage of Tyr-|-Gly bond in the picornavirus polyprotein. In other picornavirus reactions Glu may be substituted for Gln, and Ser or Thr for Gly.
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Enzyme class 5:
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Chains 1, 2, 3, 4:
E.C.3.6.1.15
- nucleoside-triphosphate phosphatase.
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Reaction:
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a ribonucleoside 5'-triphosphate + H2O = a ribonucleoside 5'-diphosphate + phosphate + H+
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ribonucleoside 5'-triphosphate
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+
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H2O
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=
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ribonucleoside 5'-diphosphate
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+
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phosphate
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+
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H(+)
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Note, where more than one E.C. class is given (as above), each may
correspond to a different protein domain or, in the case of polyprotein
precursors, to a different mature protein.
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Molecule diagrams generated from .mol files obtained from the
KEGG ftp site
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Links
