› 8sv5

X-ray diffraction
2.16Å resolution

Crystal structure of Bacillus anthracis dihydroneopterin aldolase in complex with 6-hydroxymethyl-7,8-dihydropterin

Released:
DOI: 10.2210/pdb8sv5/pdb
PDB entry 8sv5 coloured by chain, front view.
PDB entry 8sv5 coloured by chain, side view.
PDB entry 8sv5 coloured by chain, top view.
Source organism: Bacillus anthracis
Entry authors: Shaw GX, Li Y, Yan H, Ji X

Function and Biology Details

Reaction catalysed: 
7,8-dihydroneopterin = 6-hydroxymethyl-7,8-dihydropterin + glycolaldehyde
Biochemical function:
Biological process:
Cellular component:

Structure analysis Details

Assembly composition:
homo octamer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-105716 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
7,8-dihydroneopterin aldolase Chains: A, B, C, D, E, F, G, H
Molecule details ›
Chains: A, B, C, D, E, F, G, H
Length: 120 amino acids
Theoretical weight: 13.99 KDa
Source organism: Bacillus anthracis
Expression system: Escherichia coli
UniProt:
  • Canonical: A0A6L7HSV1 (Residues: 1-120; Coverage: 100%)
Gene names: GBAA_0072, folB
Sequence domains: Dihydroneopterin aldolase

Ligands and Environments

2 bound ligands:
Ligand PH2 8 x PH2
Ligand EDO 2 x EDO
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: APS BEAMLINE 22-ID
Spacegroup: P21
Unit cell:
a: 63.421Å b: 101.849Å c: 77.204Å
α: 90° β: 101.17° γ: 90°
R-values:
R R work R free
0.183 0.181 0.227
Expression system: Escherichia coli

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