› 8oyd

Solution NMR

TrkB transmembrane domain NMR structure in DMPC/DHPC bicelles

Released:
DOI: 10.2210/pdb8oyd/pdb
PDB entry 8oyd coloured by chain, ensemble of 10 models, front view.
PDB entry 8oyd coloured by chain, ensemble of 10 models, side view.
PDB entry 8oyd coloured by chain, ensemble of 10 models, top view.
Source organism: Homo sapiens
Entry authors: Kot EF, Mineev KS, Goncharuk SA

Function and Biology Details

Reaction catalysed: 
ATP + a [protein]-L-tyrosine = ADP + a [protein]-L-tyrosine phosphate
Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
homo dimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-244441 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
BDNF/NT-3 growth factors receptor Chains: A, B
Molecule details ›
Chains: A, B
Length: 45 amino acids
Theoretical weight: 4.98 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: Q16620 (Residues: 422-466; Coverage: 6%)
Gene names: NTRK2, TRKB

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
Chemical shift assignment: 46%
Refinement method: torsion angle dynamics
Expression system: Escherichia coli

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