› 8w84

X-ray diffraction
2.1Å resolution

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
Cellular component:

Structure analysis Details

Assembly composition:
hetero tetramer (preferred)
PDBe Complex ID:
PDB-CPX-234987 (preferred)
Entry contents:
4 distinct polypeptide molecules
Macromolecules (4 distinct):
DQN0344AE02 Fab heavy chain Chain: A
Molecule details ›
Chain: A
Length: 228 amino acids
Theoretical weight: 24.57 KDa
Source organism: Homo sapiens
Expression system: Homo sapiens
DQN0344AE02 Fab light chain Chain: B
Molecule details ›
Chain: B
Length: 215 amino acids
Theoretical weight: 23.48 KDa
Source organism: Homo sapiens
Expression system: Homo sapiens
HLA class II histocompatibility antigen, DQ alpha 1 chain Chain: C
Molecule details ›
Chain: C
Length: 189 amino acids
Theoretical weight: 21.4 KDa
Source organism: Homo sapiens
Expression system: Homo sapiens
UniProt:
  • Canonical: P01909 (Residues: 24-206; Coverage: 79%)
Gene name: HLA-DQA1
Sequence domains:
Ig-like domain-containing protein Chain: D
Molecule details ›
Chain: D
Length: 226 amino acids
Theoretical weight: 25.84 KDa
Source organism: Homo sapiens
Expression system: Homo sapiens
UniProt:
  • Canonical: O19712 (Residues: 1-190; Coverage: 83%)
Gene name: HLA-DQB1
Sequence domains:

Ligands and Environments

1 bound ligand:
Ligand NAG 2 x NAG
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: SPRING-8 BEAMLINE BL45XU
Spacegroup: I212121
Unit cell:
a: 82.86Å b: 138.707Å c: 201.928Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.263 0.26 0.325
Expression system: Homo sapiens

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