› 7q1t

X-ray diffraction
1.68Å resolution

A de novo designed hetero-dimeric antiparallel coiled coil apCC-Di-AB

Released:
DOI: 10.2210/pdb7q1t/pdb
PDB entry 7q1t coloured by chain, front view.
PDB entry 7q1t coloured by chain, side view.
PDB entry 7q1t coloured by chain, top view.
Source organism: synthetic construct
Primary publication:
De novo designed peptides for cellular delivery and subcellular localisation.
Rhys GG, Cross JA, Dawson WM, Thompson HF, Shanmugaratnam S, Savery NJ, Dodding MP, Höcker B, Woolfson DN
Nat Chem Biol (2022)
PMID: 35836017

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
hetero dimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-168649 (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
apCC-Di-A Chain: A
Molecule details ›
Chain: A
Length: 30 amino acids
Theoretical weight: 3.25 KDa
Source organism: synthetic construct
Expression system: Not provided
apCC-Di-B Chain: B
Molecule details ›
Chain: B
Length: 30 amino acids
Theoretical weight: 3.5 KDa
Source organism: synthetic construct
Expression system: Not provided

Ligands and Environments

2 bound ligands:
Ligand POL 2 x POL
Ligand SO4 1 x SO4
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: BESSY BEAMLINE 14.1
Spacegroup: I41
Unit cell:
a: 47.219Å b: 47.219Å c: 70.169Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.19 0.186 0.221
Expression system: Not provided

Quick links

Citations

3 review citations

Understanding a protein fold: The physics, chemistry, and biology of α-helical coiled coils.
Woolfson DN. (2023)
2 more