› 7cj3

X-ray diffraction
2.6Å resolution

Crystal structure of the transmembrane domain of Salpingoeca rosetta rhodopsin phosphodiesterase

Released:
DOI: 10.2210/pdb7cj3/pdb
PDB entry 7cj3 coloured by chain, front view.
PDB entry 7cj3 coloured by chain, side view.
PDB entry 7cj3 coloured by chain, top view.
Source organism: Salpingoeca rosetta
Primary publication:
Structural insights into the mechanism of rhodopsin phosphodiesterase.
Ikuta T, Shihoya W, Sugiura M, Yoshida K, Watari M, Tokano T, Yamashita K, Katayama K, Tsunoda SP, Uchihashi T, Kandori H, Nureki O
Nat Commun 11 5605 (2020)
PMID: 33154353

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
Sequence domain:

Structure analysis Details

Assembly composition:
homo dimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-123407 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Phosphodiesterase Chains: A, B
Molecule details ›
Chains: A, B
Length: 291 amino acids
Theoretical weight: 32.53 KDa
Source organism: Salpingoeca rosetta
Expression system: Homo sapiens
UniProt:
  • Canonical: F2TZN0 (Residues: 33-316; Coverage: 40%)
Gene name: PTSG_02023
Sequence domains: Bacteriorhodopsin-like protein

Ligands and Environments

2 bound ligands:
Ligand RET 2 x RET
Ligand OLC 14 x OLC
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: SPRING-8 BEAMLINE BL32XU
Spacegroup: P212121
Unit cell:
a: 65.55Å b: 74.14Å c: 117.38Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.249 0.246 0.295
Expression system: Homo sapiens

Quick links

Citations

4 review citations

Towards the Idea of Molecular Brains.
Timsit et al. (2021)
3 more

2 mentions without citation

Far-Red Absorbing Rhodopsins, Insights From Heterodimeric Rhodopsin-Cyclases.
Broser M. (2021)
1 more