› 7f68

X-ray diffraction
1.24Å resolution

Crystal structure of N-ras S89D

Released:
DOI: 10.2210/pdb7f68/pdb
PDB entry 7f68 coloured by chain, front view.
PDB entry 7f68 coloured by chain, side view.
PDB entry 7f68 coloured by chain, top view.
Source organism: Homo sapiens
Entry authors: Li Y, Sun Q

Function and Biology Details

Reaction catalysed: 
GTP + H(2)O = GDP + phosphate
Biochemical function:
Biological process:
Cellular component:
Sequence domains:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-133953 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
GTPase NRas Chain: A
Molecule details ›
Chain: A
Length: 169 amino acids
Theoretical weight: 19.27 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: P01111 (Residues: 1-169; Coverage: 89%)
Gene names: HRAS1, NRAS
Sequence domains: Ras family

Ligands and Environments

3 bound ligands:
Ligand GTP 1 x GTP
Ligand MG 1 x MG
Ligand SO4 1 x SO4
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: SSRF BEAMLINE BL18U1
Spacegroup: P3221
Unit cell:
a: 67.963Å b: 67.963Å c: 78.374Å
α: 90° β: 90° γ: 120°
R-values:
R R work R free
0.124 0.123 0.144
Expression system: Escherichia coli

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