Function and Biology

Crystal structure of pentalenene synthase complexed with Mg2+ ions

Source organism: Streptomyces sp.
Biochemical function: pentalenene synthase activity
Biological process: antibiotic biosynthetic process
Cellular component: not assigned

EC 4.2.3.7: Pentalenene synthase

Reaction catalysed:
(2E,6E)-farnesyl diphosphate = pentalenene + diphosphate
Systematic name:
(2E,6E)-farnesyl-diphosphate diphosphate-lyase (cyclizing, pentalenene-forming)
Alternative Name(s):
  • Pentalenene synthetase

GO terms

Biochemical function:
Biological process:
Cellular component:
  • not assigned

Sequence family

Pfam Protein family (Pfam)
PF19086
Domain description: Terpene synthase family 2, C-terminal metal binding
Occurring in:
  1. Pentalenene synthase
The deposited structure of PDB entry 6wkc contains 2 copies of Pfam domain PF19086 (Terpene synthase family 2, C-terminal metal binding) in Pentalenene synthase. Showing 1 copy in chain A.

InterPro InterPro annotations
IPR008949
Domain description: Isoprenoid synthase domain superfamily
Occurring in:
  1. Pentalenene synthase
IPR034686
Domain description: Terpene cyclase-like 2
Occurring in:
  1. Pentalenene synthase