› 6sdp

X-ray diffraction
1.45Å resolution

Trypanosoma cruzi farnesyl diphosphate synthase in complex with fragment 4np

Released:
DOI: 10.2210/pdb6sdp/pdb
PDB entry 6sdp coloured by chain, front view.
PDB entry 6sdp coloured by chain, side view.
PDB entry 6sdp coloured by chain, top view.
Source organism: Trypanosoma cruzi
Entry authors: Magari F, Heine A, Klebe G

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
  • not assigned
Sequence domains:

Structure analysis Details

Assembly composition:
homo dimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-186689 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Farnesyl diphosphate synthase Chain: A
Molecule details ›
Chain: A
Length: 362 amino acids
Theoretical weight: 41.21 KDa
Source organism: Trypanosoma cruzi
Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: Q8WS26 (Residues: 64-425; Coverage: 85%)
Sequence domains: Polyprenyl synthetase

Ligands and Environments

3 bound ligands:
Ligand SO4 1 x SO4
Ligand ZN 2 x ZN
Ligand NPO 1 x NPO
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: PETRA III, EMBL c/o DESY BEAMLINE P13 (MX1)
Spacegroup: P6122
Unit cell:
a: 57.864Å b: 57.864Å c: 397.732Å
α: 90° β: 90° γ: 120°
R-values:
R R work R free
0.168 0.167 0.188
Expression system: Escherichia coli BL21(DE3)

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