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Structure of Mcl-1 in complex with compound 10d

Source organism: Homo sapiens
Biochemical function: catalytic activity
Biological process: regulation of apoptotic process
Cellular component: not assigned

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GO terms

Biochemical function:
Biological process:
Cellular component:
  • not assigned

Sequence family

Pfam Protein family (Pfam)
PF00452
Domain description: Apoptosis regulator proteins, Bcl-2 family
Occurring in:
  1. Induced myeloid leukemia cell differentiation protein Mcl-1
The deposited structure of PDB entry 6qz8 contains 1 copy of Pfam domain PF00452 (Apoptosis regulator proteins, Bcl-2 family) in Induced myeloid leukemia cell differentiation protein Mcl-1. Showing 1 copy in chain A.

InterPro InterPro annotations
IPR026298
Domain description: Bcl-2 family
Occurring in:
  1. Induced myeloid leukemia cell differentiation protein Mcl-1
IPR013281
Domain description: Apoptosis regulator, Mcl-1
Occurring in:
  1. Induced myeloid leukemia cell differentiation protein Mcl-1
IPR036834
Domain description: Bcl-2-like superfamily
Occurring in:
  1. Induced myeloid leukemia cell differentiation protein Mcl-1
IPR020726
Domain description: Apoptosis regulator, Bcl-2, BH2 motif, conserved site
Occurring in:
  1. Induced myeloid leukemia cell differentiation protein Mcl-1
IPR020717
Domain description: Apoptosis regulator, Bcl-2, BH1 motif, conserved site
Occurring in:
  1. Induced myeloid leukemia cell differentiation protein Mcl-1
IPR046371
Domain description: Bcl-2, Bcl-2 homology region 1-3
Occurring in:
  1. Induced myeloid leukemia cell differentiation protein Mcl-1
IPR002475
Domain description: Bcl2-like
Occurring in:
  1. Induced myeloid leukemia cell differentiation protein Mcl-1
IPR020728
Domain description: Apoptosis regulator, Bcl-2, BH3 motif, conserved site
Occurring in:
  1. Induced myeloid leukemia cell differentiation protein Mcl-1
IPR011146
Domain description: HIT-like domain
Occurring in:
  1. Induced myeloid leukemia cell differentiation protein Mcl-1

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