› 6d8i

X-ray diffraction
1.65Å resolution

Mycobacterium tuberculosis polyketide synthase 13 N-terminal acyl carrier protein domain

Released:
DOI: 10.2210/pdb6d8i/pdb
PDB entry 6d8i coloured by chain, front view.
PDB entry 6d8i coloured by chain, side view.
PDB entry 6d8i coloured by chain, top view.
Source organism: Mycobacterium tuberculosis H37Rv
Entry authors: Tang S, Sacchettini J

Function and Biology Details

Biochemical function:
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domains:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-125183 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Polyketide synthase Pks13 Chain: A
Molecule details ›
Chain: A
Length: 87 amino acids
Theoretical weight: 9.54 KDa
Source organism: Mycobacterium tuberculosis H37Rv
Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: I6X8D2 (Residues: 10-93; Coverage: 5%)
Gene names: Rv3800c, pks13
Sequence domains: Phosphopantetheine attachment site

Ligands and Environments

3 bound ligands:
Ligand CA 3 x CA
Ligand PGE 1 x PGE
Ligand EDO 3 x EDO
1 modified residue:
Ligand MSE 4 x MSE

Experiments and Validation Details

Entry percentile scores
X-ray source: APS BEAMLINE 23-ID-D
Spacegroup: P43212
Unit cell:
a: 51.646Å b: 51.646Å c: 75.109Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.166 0.164 0.18
Expression system: Escherichia coli BL21(DE3)

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