› 5k7v

X-ray diffraction
3.16Å resolution

Computational Design of Self-Assembling Cyclic Protein Homooligomers

Released:
DOI: 10.2210/pdb5k7v/pdb
PDB entry 5k7v coloured by chain, front view.
PDB entry 5k7v coloured by chain, side view.
PDB entry 5k7v coloured by chain, top view.
Source organism: synthetic construct
Primary publication:
Computational design of self-assembling cyclic protein homo-oligomers.
Fallas JA, Ueda G, Sheffler W, Nguyen V, McNamara DE, Sankaran B, Pereira JH, Parmeggiani F, Brunette TJ, Cascio D, Yeates TR, Zwart P, Baker D
Nat Chem 9 353-360 (2017)
PMID: 28338692

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domains:

Structure analysis Details

Assembly composition:
homo trimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-165881 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Designed protein HR00C3 Chains: A, B, C
Molecule details ›
Chains: A, B, C
Length: 288 amino acids
Theoretical weight: 31.44 KDa
Source organism: synthetic construct
Expression system: Escherichia coli

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: ALS BEAMLINE 8.2.2
Spacegroup: P321
Unit cell:
a: 159.005Å b: 159.005Å c: 94.982Å
α: 90° β: 90° γ: 120°
R-values:
R R work R free
0.213 0.201 0.223
Expression system: Escherichia coli

Quick links

Citations

10 review citations

Evolving SAXS versatility: solution X-ray scattering for macromolecular architecture, functional landscapes, and integrative structural biology.
Brosey et al. (2019)
9 more

6 mentions without citation

Unwinding the twister ribozyme: from structure to mechanism.
Gebetsberger et al. (2017)
5 more