› 5fq6

X-ray diffraction
2.8Å resolution

Crystal structure of the SusCD complex BT2261-2264 from Bacteroides thetaiotaomicron

Released:
DOI: 10.2210/pdb5fq6/pdb
PDB entry 5fq6 coloured by chain, front view.
PDB entry 5fq6 coloured by chain, side view.
PDB entry 5fq6 coloured by chain, top view.
Source organism: Bacteroides thetaiotaomicron
Primary publication:
Structural basis for nutrient acquisition by dominant members of the human gut microbiota.
Glenwright AJ, Pothula KR, Bhamidimarri SP, Chorev DS, Baslé A, Firbank SJ, Zheng H, Robinson CV, Winterhalter M, Kleinekathöfer U, Bolam DN, van den Berg B
Nature 541 407-411 (2017)
PMID: 28077872

Function and Biology Details

Biochemical function:
Biological process:
  • not assigned
Cellular component:
Sequence domains:

Structure analysis Details

Assembly composition:
hetero octamer (preferred)
PDBe Complex ID:
PDB-CPX-165662 (preferred)
Entry contents:
4 distinct polypeptide molecules
Macromolecules (4 distinct):
Lipoprotein Chains: A, C, H, L
Molecule details ›
Chains: A, C, H, L
Length: 480 amino acids
Theoretical weight: 53.15 KDa
Source organism: Bacteroides thetaiotaomicron
UniProt:
  • Canonical: Q8A5H6 (Residues: 19-498; Coverage: 100%)
Gene name: BT_2263
Sequence domains: Starch-binding associating with outer membrane
Structure domains: Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat
TonB-dependent receptor plug domain-containing protein Chains: B, D, I, M
Molecule details ›
Chains: B, D, I, M
Length: 984 amino acids
Theoretical weight: 108.95 KDa
Source organism: Bacteroides thetaiotaomicron
UniProt:
  • Canonical: Q8A5H5 (Residues: 1-984; Coverage: 100%)
Gene name: BT_2264
Sequence domains: TonB-dependent Receptor Plug Domain
Lipid-binding hydrolase Chains: E, F, J, N
Molecule details ›
Chains: E, F, J, N
Length: 148 amino acids
Theoretical weight: 16.43 KDa
Source organism: Bacteroides thetaiotaomicron
UniProt:
  • Canonical: Q8A5H8 (Residues: 19-166; Coverage: 100%)
Gene name: BT_2261
Sequence domains: Lipid-binding putative hydrolase
Structure domains: Lipocalin
BT_2261 Chains: G, K, O, P
Molecule details ›
Chains: G, K, O, P
Length: 10 amino acids
Theoretical weight: 589 Da
Source organism: Bacteroides thetaiotaomicron

Ligands and Environments

3 bound ligands:
Ligand KR0 4 x KR0
Ligand NA 4 x NA
Ligand CA 4 x CA
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: DIAMOND BEAMLINE I03
Spacegroup: P21
Unit cell:
a: 222.027Å b: 91.941Å c: 261.219Å
α: 90° β: 98.23° γ: 90°
R-values:
R R work R free
0.2 0.198 0.255

Quick links

Citations

20 review citations

Introduction to the human gut microbiota.
Thursby et al. (2017)
19 more

2 mentions without citation

Structural basis for nutrient acquisition by dominant members of the human gut microbiota.
Glenwright et al. (2017)
1 more