› 4v15

X-ray diffraction
1.5Å resolution

Crystal structure of D-threonine aldolase from Alcaligenes xylosoxidans

Released:
DOI: 10.2210/pdb4v15/pdb
PDB entry 4v15 coloured by chain, front view.
PDB entry 4v15 coloured by chain, side view.
PDB entry 4v15 coloured by chain, top view.
Source organism: Achromobacter xylosoxidans
Primary publication:
The crystal structure of D-threonine aldolase from Alcaligenes xylosoxidans provides insight into a metal ion assisted PLP-dependent mechanism.
Uhl MK, Oberdorfer G, Steinkellner G, Riegler-Berket L, Mink D, van Assema F, Schürmann M, Gruber K
PLoS One 10 e0124056 (2015)
PMID: 25884707

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
homo dimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-102259 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
D-serine dehydratase-like domain-containing protein Chains: A, B
Molecule details ›
Chains: A, B
Length: 379 amino acids
Theoretical weight: 39.84 KDa
Source organism: Achromobacter xylosoxidans
Expression system: Escherichia coli BL21
UniProt:

Ligands and Environments


Cofactor: Ligand PLP 4 x PLP
2 bound ligands:
Ligand MN 2 x MN
Ligand NA 2 x NA
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: SLS BEAMLINE X06DA
Spacegroup: P21
Unit cell:
a: 62.267Å b: 84.278Å c: 72.852Å
α: 90° β: 111.9° γ: 90°
R-values:
R R work R free
0.15 0.148 0.177
Expression system: Escherichia coli BL21

Quick links

Citations

3 review citations

Current Advances on Structure-Function Relationships of Pyridoxal 5'-Phosphate-Dependent Enzymes.
Liang et al. (2019)
2 more

3 mentions without citation

Threonine aldolases: perspectives in engineering and screening the enzymes with enhanced substrate and stereo specificities.
Fesko K. (2016)
2 more