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Crystal structure of the CCM2 C-terminal Harmonin Homology Domain (HHD)

Source organism: Homo sapiens
Biochemical function: not assigned
Biological process: not assigned
Cellular component: not assigned

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GO terms

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned

Sequence family

Pfam Protein family (Pfam)
PF16545
Domain description: Cerebral cavernous malformation protein, harmonin-homology
Occurring in:
  1. Cerebral cavernous malformations 2 protein
The deposited structure of PDB entry 4fqn contains 4 copies of Pfam domain PF16545 (Cerebral cavernous malformation protein, harmonin-homology ) in Cerebral cavernous malformations 2 protein. Showing 1 copy in chain A.

InterPro InterPro annotations
IPR032375
Domain description: Cerebral cavernous malformations 2, harmonin-homology domain
Occurring in:
  1. Cerebral cavernous malformations 2 protein
IPR026159
Domain description: Cerebral cavernous malformations 2
Occurring in:
  1. Cerebral cavernous malformations 2 protein

Structure domain

CATH CATH domain
1.20.1160.20
Class: Mainly Alpha
Architecture: Up-down Bundle
Topology: Paired amphipathic helix 2 (pah2 repeat)
Homology: Paired amphipathic helix 2 (pah2 repeat)
Occurring in:
  1. Cerebral cavernous malformations 2 protein
The deposited structure of PDB entry 4fqn contains 4 copies of CATH domain 1.20.1160.20 (Paired amphipathic helix 2 (pah2 repeat)) in Cerebral cavernous malformations 2 protein. Showing 1 copy in chain A.

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