X-ray diffraction
2.2Å resolution

Crystal structure of wild type FimH lectin domain in complex with heptyl alpha-D-mannopyrannoside


Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
Cellular component:

Structure analysis Details

Assembly composition:
monomeric (preferred)
PDBe Complex ID:
PDB-CPX-106845 (preferred)
Entry contents:
1 distinct polypeptide molecule
FimH mannose-binding domain-containing protein Chains: A, B
Molecule details ›
Chains: A, B
Length: 158 amino acids
Theoretical weight: 16.92 KDa
Source organism: Escherichia coli UTI89
Expression system: Escherichia coli BL21(DE3)
  • Canonical: A2IC68 (Residues: 10-167; Coverage: 70%)
Gene name: fimH
Sequence domains: FimH, mannose binding
Structure domains: Fimbrial-type adhesion domain

Ligands and Environments

1 bound ligand:
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: BESSY BEAMLINE 14.2
Spacegroup: P212121
Unit cell:
a: 60.305Å b: 68.07Å c: 95.607Å
α: 90° β: 90° γ: 90°
R R work R free
0.205 0.202 0.256
Expression system: Escherichia coli BL21(DE3)