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Crystal structure of abscisic acid bound PYL2 in complex with type 2C protein phosphatase ABI2

Source organism: Arabidopsis thaliana
Biochemical function: cation binding
Biological process: protein dephosphorylation
Cellular component: protein phosphatase inhibitor complex

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EC 3.1.3.16: Protein-serine/threonine phosphatase

Reaction catalysed:
[a protein]-serine/threonine phosphate + H(2)O = [a protein]-serine/threonine + phosphate
Systematic name:
Phosphoprotein phosphohydrolase
Alternative Name(s):
  • 3-hydroxy 3-methylglutaryl coenzymeA reductase phosphatase
  • Aspergillus awamori acid protein phosphatase
  • BCKDH phosphatase
  • Branched-chain alpha-keto acid dehydrogenase phosphatase
  • Calcineurin
  • Casein phosphatase
  • HMG-CoA reductase phosphatase
  • Phosphatase 2A
  • Phosphatase 2B
  • Phosphatase C-II
  • Phosphatase H-II
  • Phosphatase I
  • Phosphatase IB
  • Phosphatase II
  • Phosphatase III
  • Phosphatase IV
  • Phosphatase SP
  • Phosphoprotein phosphatase
  • Phosphopyruvate dehydrogenase phosphatase
  • Phosphospectrin phosphatase
  • Polycation modulated (PCM-) phosphatase
  • Protein D phosphatase
  • Protein phosphatase
  • Protein phosphatase-1
  • Protein phosphatase-2A
  • Protein phosphatase-2B
  • Protein phosphatase-2C
  • Serine/threonine specific protein phosphatase

GO terms

Sequence families

Pfam Protein families (Pfam)
PF00481
Domain description: Protein phosphatase 2C
Occurring in:
  1. Protein phosphatase 2C 77
The deposited structure of PDB entry 3ujl contains 1 copy of Pfam domain PF00481 (Protein phosphatase 2C) in Protein phosphatase 2C 77. Showing 1 copy in chain B.

PF10604
Domain description: Polyketide cyclase / dehydrase and lipid transport
Occurring in:
  1. Abscisic acid receptor PYL2
The deposited structure of PDB entry 3ujl contains 1 copy of Pfam domain PF10604 (Polyketide cyclase / dehydrase and lipid transport) in Abscisic acid receptor PYL2. Showing 1 copy in chain A.

InterPro InterPro annotations
IPR001932
Domain description: PPM-type phosphatase-like domain
Occurring in:
  1. Protein phosphatase 2C 77
IPR036457
Domain description: PPM-type phosphatase-like domain superfamily
Occurring in:
  1. Protein phosphatase 2C 77
IPR000222
Domain description: PPM-type phosphatase, divalent cation binding
Occurring in:
  1. Protein phosphatase 2C 77
IPR015655
Domain description: Protein phosphatase 2C
Occurring in:
  1. Protein phosphatase 2C 77
IPR019587
Domain description: Polyketide cyclase/dehydrase
Occurring in:
  1. Abscisic acid receptor PYL2
IPR023393
Domain description: START-like domain superfamily
Occurring in:
  1. Abscisic acid receptor PYL2

Structure domains

CATH CATH domains
3.60.40.10
Class: Alpha Beta
Architecture: 4-Layer Sandwich
Topology: Phosphatase 2c; domain 1
Homology: PPM-type phosphatase domain
Occurring in:
  1. Protein phosphatase 2C 77
The deposited structure of PDB entry 3ujl contains 1 copy of CATH domain 3.60.40.10 (Phosphatase 2c; domain 1) in Protein phosphatase 2C 77. Showing 1 copy in chain B.
3.30.530.20
Class: Alpha Beta
Architecture: 2-Layer Sandwich
Topology: Alpha-D-Glucose-1,6-Bisphosphate; Chain A, domain 4
Homology: Alpha-D-Glucose-1,6-Bisphosphate; Chain A, domain 4
Occurring in:
  1. Abscisic acid receptor PYL2
The deposited structure of PDB entry 3ujl contains 1 copy of CATH domain 3.30.530.20 (Alpha-D-Glucose-1,6-Bisphosphate; Chain A, domain 4) in Abscisic acid receptor PYL2. Showing 1 copy in chain A.

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