› 3hhg

X-ray diffraction
3.2Å resolution

Structure of CrgA, a LysR-type transcriptional regulator from Neisseria meningitidis.

Released:
DOI: 10.2210/pdb3hhg/pdb
PDB entry 3hhg coloured by chain, front view.
PDB entry 3hhg coloured by chain, side view.
PDB entry 3hhg coloured by chain, top view.
Source organism: Neisseria meningitidis serogroup B
Primary publication:
The structure of CrgA from Neisseria meningitidis reveals a new octameric assembly state for LysR transcriptional regulators.
Sainsbury S, Lane LA, Ren J, Gilbert RJ, Saunders NJ, Robinson CV, Stuart DI, Owens RJ
OpenAccess logo Nucleic Acids Res 37 4545-58 (2009)
PMID: 19474343

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
  • not assigned
Sequence domains:

Structure analysis Details

Assembly composition:
homo octamer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-191689 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
HTH-type transcriptional regulator CrgA Chains: A, B, C, D, E, F, G, H
Molecule details ›
Chains: A, B, C, D, E, F, G, H
Length: 306 amino acids
Theoretical weight: 34.03 KDa
Source organism: Neisseria meningitidis serogroup B
Expression system: Escherichia coli
UniProt:
  • Canonical: Q9JXW7 (Residues: 1-299; Coverage: 100%)
Gene names: NMB1856, crgA
Sequence domains:
Structure domains:

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: ESRF BEAMLINE ID14-4
Spacegroup: P212121
Unit cell:
a: 104.638Å b: 119.091Å c: 250.204Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.218 0.214 0.286
Expression system: Escherichia coli

Quick links

Citations

2 review citations

Regulation of carbohydrate degradation pathways in Pseudomonas involves a versatile set of transcriptional regulators.
Udaondo et al. (2018)
1 more

8 mentions without citation

Cell-Wall Recycling of the Gram-Negative Bacteria and the Nexus to Antibiotic Resistance.
Dik et al. (2018)
7 more