› 2m18

Solution NMR

Structure of stacked G-quadruplex formed by human TERRA sequence in potassium solution

Released:
DOI: 10.2210/pdb2m18/pdb
PDB entry 2m18 coloured by chain, ensemble of 10 models, front view.
PDB entry 2m18 coloured by chain, ensemble of 10 models, side view.
PDB entry 2m18 coloured by chain, ensemble of 10 models, top view.
Source organism: Synthetic construct
Primary publication:
Structure of human telomeric RNA (TERRA): stacking of two G-quadruplex blocks in K(+) solution.
Martadinata H, Phan AT
Biochemistry 52 2176-83 (2013)
PMID: 23445442

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
homo tetramer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-196483 (preferred)
Entry contents:
1 distinct RNA molecule
Macromolecule:
RNA (5'-R(*GP*GP*GP*UP*UP*AP*GP*GP*GP*U)-3') Chains: A, B, C, D
Molecule details ›
Chains: A, B, C, D
Length: 10 nucleotides
Theoretical weight: 3.27 KDa
Source organism: Synthetic construct
Expression system: Not provided

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
Chemical shift assignment: 29%
Refinement method: DGSA-distance geometry simulated annealing, molecular dynamics
Expression system: Not provided

Quick links

Citations

14 review citations

Metal Cations in G-Quadruplex Folding and Stability.
Bhattacharyya et al. (2016)
13 more

5 mentions without citation

Structural dynamics of propeller loop: towards folding of RNA G-quadruplex.
Havrila et al. (2018)
4 more