› › Function and Biology

REGULATOR FROM ESCHERICHIA COLI

Source organism: Escherichia coli
Biochemical function: metal ion binding
Biological process: negative regulation of DNA-templated transcription initiation
Cellular component: ModE complex

Quick links

GO terms

Sequence family

Pfam Protein family (Pfam)
PF03459
Domain description: TOBE domain
Occurring in:
  1. DNA-binding transcriptional dual regulator ModE
The deposited structure of PDB entry 1b9n contains 4 copies of Pfam domain PF03459 (TOBE domain) in DNA-binding transcriptional dual regulator ModE. Showing 2 copies in chain A.

InterPro InterPro annotations
IPR004606
Domain description: Molybdenum-pterin binding domain
Occurring in:
  1. DNA-binding transcriptional dual regulator ModE
IPR005116
Domain description: Transport-associated OB, type 1
Occurring in:
  1. DNA-binding transcriptional dual regulator ModE
IPR008995
Domain description: Molybdate/tungstate binding, C-terminal
Occurring in:
  1. DNA-binding transcriptional dual regulator ModE
IPR000847
Domain description: Transcription regulator HTH, LysR
Occurring in:
  1. DNA-binding transcriptional dual regulator ModE
IPR003725
Domain description: Molybdenum-binding protein ModE, N-terminal
Occurring in:
  1. DNA-binding transcriptional dual regulator ModE
IPR036390
Domain description: Winged helix DNA-binding domain superfamily
Occurring in:
  1. DNA-binding transcriptional dual regulator ModE
IPR016462
Domain description: Molybdate-dependent transcriptional regulator ModE
Occurring in:
  1. DNA-binding transcriptional dual regulator ModE
IPR036388
Domain description: Winged helix-like DNA-binding domain superfamily
Occurring in:
  1. DNA-binding transcriptional dual regulator ModE

Structure domains

CATH CATH domains
2.40.50.100
Class: Mainly Beta
Architecture: Beta Barrel
Topology: OB fold (Dihydrolipoamide Acetyltransferase, E2P)
Homology: OB fold (Dihydrolipoamide Acetyltransferase, E2P)
Occurring in:
  1. DNA-binding transcriptional dual regulator ModE
The deposited structure of PDB entry 1b9n contains 4 copies of CATH domain 2.40.50.100 (OB fold (Dihydrolipoamide Acetyltransferase, E2P)) in DNA-binding transcriptional dual regulator ModE. Showing 2 copies in chain A.
1.10.10.10
Class: Mainly Alpha
Architecture: Orthogonal Bundle
Topology: Arc Repressor Mutant, subunit A
Homology: Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain
Occurring in:
  1. DNA-binding transcriptional dual regulator ModE
The deposited structure of PDB entry 1b9n contains 2 copies of CATH domain 1.10.10.10 (Arc Repressor Mutant, subunit A) in DNA-binding transcriptional dual regulator ModE. Showing 1 copy in chain A.
SCOP SCOP annotations
50335
Class: All beta proteins
Fold: OB-fold
Superfamily: MOP-like
Occurring in:
  1. DNA-binding transcriptional dual regulator ModE
The deposited structure of PDB entry 1b9n contains 4 copies of SCOP domain 50335 (BiMOP, duplicated molybdate-binding domain) in DNA-binding transcriptional dual regulator ModE. Showing 2 copies in chain A.
46810
Class: All alpha proteins
Fold: DNA/RNA-binding 3-helical bundle
Superfamily: "Winged helix" DNA-binding domain
Occurring in:
  1. DNA-binding transcriptional dual regulator ModE
The deposited structure of PDB entry 1b9n contains 2 copies of SCOP domain 46810 (N-terminal domain of molybdate-dependent transcriptional regulator ModE) in DNA-binding transcriptional dual regulator ModE. Showing 1 copy in chain A.

Quick links