6y17

X-ray diffraction
1.56Å resolution

Crystal structure of an NCoR1BBD2-BCL6BTB chimera in complex with nebulinSH3-NCoR1BBD1

Released:

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
hetero tetramer (preferred)
PDBe Complex ID:
PDB-CPX-130921 (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
B-cell lymphoma 6 protein; Nuclear receptor corepressor 1 Chains: A, B
Molecule details ›
Chains: A, B
Length: 137 amino acids
Theoretical weight: 15.6 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: O75376 (Residues: 1733-1741; Coverage: 0%)
  • Canonical: P41182 (Residues: 6-129; Coverage: 18%)
Gene names: BCL5, BCL6, KIAA1047, LAZ3, NCOR1, ZBTB27, ZNF51
Sequence domains: BTB/POZ domain
Nebulin; Nuclear receptor corepressor 1 Chains: C, D
Molecule details ›
Chains: C, D
Length: 82 amino acids
Theoretical weight: 8.86 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: O75376 (Residues: 1340-1356; Coverage: 1%)
  • Canonical: P20929 (Residues: 8466-8525; Coverage: 1%)
Gene names: KIAA1047, NCOR1, NEB

Ligands and Environments

1 bound ligand:
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: DIAMOND BEAMLINE I24
Spacegroup: P1
Unit cell:
a: 39.46Å b: 47.303Å c: 59.781Å
α: 95.865° β: 95.6° γ: 94.205°
R-values:
R R work R free
0.178 0.177 0.201
Expression system: Escherichia coli