› 6a6p

X-ray diffraction
2.1Å resolution

Crystal Structure of Peroxisome Proliferator-Activated Receptor Delta (PPARd)LBD in Complex with DN003316

Released:
DOI: 10.2210/pdb6a6p/pdb
PDB entry 6a6p coloured by chain, front view.
PDB entry 6a6p coloured by chain, side view.
PDB entry 6a6p coloured by chain, top view.
Source organism: Homo sapiens
Entry authors: Chin JW, Cho SJ, Song JY, Ha JH

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
Sequence domains:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-169863 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Peroxisome proliferator-activated receptor delta Chains: A, B
Molecule details ›
Chains: A, B
Length: 270 amino acids
Theoretical weight: 30.85 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: Q03181 (Residues: 171-440; Coverage: 61%)
Gene names: NR1C2, PPARB, PPARD
Sequence domains: Ligand-binding domain of nuclear hormone receptor

Ligands and Environments

3 bound ligands:
Ligand 9RF 2 x 9RF
Ligand B7G 2 x B7G
Ligand PE3 2 x PE3
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: PAL/PLS BEAMLINE 5C (4A)
Spacegroup: P21
Unit cell:
a: 39.605Å b: 95.749Å c: 96.936Å
α: 90° β: 97.91° γ: 90°
R-values:
R R work R free
0.195 0.194 0.228
Expression system: Escherichia coli

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