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PISA Interface List.

Session Map (id=719-04-HCK)

Interfaces in PDB 6cms crystal.
Space symmetry group: P 2 21 21. Resolution: 2.68 Å

CLOSED STRUCTURE OF ACTIVE SHP2 MUTANT E76K BOUND TO SHP099 INHIBITOR

Interfaces

##		Structure 1				×	Structure 2						interface area, Å²	ΔⁱG kcal/mol	ΔⁱG P-value	N_HB	N_SB	N_DS	CSS
NN	«»	Range	ⁱN_at	ⁱN_res	Surface Å²	×	Range	Symmetry op-n	Sym.ID	ⁱN_at	ⁱN_res	Surface Å²	interface area, Å²	ΔⁱG kcal/mol	ΔⁱG P-value	N_HB	N_SB	N_DS	CSS
`1`		A	`109`	`36`	`22329`	`x`	A	x-1,y,z	`1_455`	`104`	`30`	`22329`	`951.6`	`-6.3`	`0.276`	`3`	`5`	`0`	`0.000`
`2`		A	`75`	`20`	`22329`	`◊`	A	x,-y+1,-z+2	`2_567`	`75`	`20`	`22329`	`669.6`	`-11.5`	`0.027`	`2`	`0`	`0`	`0.000`
`3`		A	`62`	`21`	`22329`	`◊`	A	x,-y,-z+2	`2_557`	`62`	`21`	`22329`	`524.4`	`-3.1`	`0.377`	`2`	`0`	`0`	`0.000`
`4`		A	`44`	`14`	`22329`	`x`	A	-x+3,y-1/2,-z+5/2	`3_847`	`42`	`12`	`22329`	`385.1`	`0.5`	`0.611`	`1`	`6`	`0`	`0.000`
`5`		[5OD]A:601	`22`	`1`	`530`	`f`	A	x,y,z	`1_555`	`54`	`18`	`22329`	`371.9`	`-9.7`	`0.364`	`2`	`0`	`0`	`0.100`
`6`		A	`39`	`15`	`22329`	`x`	A	x,y-1,z	`1_545`	`39`	`14`	`22329`	`334.9`	`1.2`	`0.722`	`2`	`1`	`0`	`0.000`
`7`		A	`7`	`4`	`22329`	`x`	A	-x+2,y-1/2,-z+5/2	`3_747`	`10`	`3`	`22329`	`77.0`	`-0.0`	`0.569`	`0`	`0`	`0`	`0.000`
`8`		A	`9`	`3`	`22329`	`x`	A	x-1,y-1,z	`1_445`	`7`	`3`	`22329`	`45.6`	`-0.4`	`0.480`	`0`	`0`	`0`	`0.000`

PDBe PISA v1.52 [20/10/2014]