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PISA Interface List.

Session Map (id=668-IA-4G8)

Interfaces in PDB 5tq4 crystal.
Space symmetry group: C 2 2 21. Resolution: 2.30 Å

DESIGN AND SYNTHESIS OF A PAN-JAK KINASE INHIBITOR CLINICAL CANDIDATE (PF-06263276) SUITABLE FOR INHALED AND TOPICAL DELIVERY FOR THE TREATMENT OF INFLAMMATORY DISEASES OF THE LUNGS AND SKIN

Interfaces

##		Structure 1				×	Structure 2						interface area, Å²	ΔⁱG kcal/mol	ΔⁱG P-value	N_HB	N_SB	N_DS	CSS
NN	«»	Range	ⁱN_at	ⁱN_res	Surface Å²	×	Range	Symmetry op-n	Sym.ID	ⁱN_at	ⁱN_res	Surface Å²	interface area, Å²	ΔⁱG kcal/mol	ΔⁱG P-value	N_HB	N_SB	N_DS	CSS
`1`		A	`81`	`21`	`16255`	`◊`	A	x,-y,-z	`4_555`	`81`	`21`	`16255`	`588.3`	`1.7`	`0.762`	`8`	`4`	`0`	`0.000`
`2`		A	`64`	`19`	`16255`	`x`	A	x-1,y,z	`1_455`	`49`	`21`	`16255`	`472.6`	`-2.5`	`0.410`	`3`	`1`	`0`	`0.000`
`3`		A	`51`	`12`	`16255`	`◊`	A	-x+1,y,-z+1/2	`3_655`	`51`	`12`	`16255`	`468.3`	`1.1`	`0.717`	`2`	`2`	`0`	`0.000`
`4`		[7GY]A:4000	`21`	`1`	`474`	`f`	A	x,y,z	`1_555`	`46`	`19`	`16255`	`338.0`	`0.8`	`0.242`	`5`	`0`	`0`	`0.100`
`5`		A	`17`	`7`	`16255`	`x`	A	x-1/2,y+1/2,z	`5_455`	`31`	`8`	`16255`	`210.9`	`0.5`	`0.654`	`5`	`0`	`0`	`0.000`
`6`		A	`12`	`6`	`16255`	`x`	A	x-1/2,y-1/2,z	`5_445`	`12`	`5`	`16255`	`99.6`	`1.0`	`0.757`	`1`	`0`	`0`	`0.000`
`7`		A	`1`	`1`	`16255`	`◊`	A	-x,y,-z+1/2	`3_555`	`1`	`1`	`16255`	`2.3`	`0.1`	`0.718`	`0`	`0`	`0`	`0.000`
`8`		A	`1`	`1`	`16255`	`x`	A	x-1,-y,-z	`4_455`	`1`	`1`	`16255`	`0.8`	`0.0`	`0.704`	`0`	`0`	`0`	`0.000`

PDBe PISA v1.52 [20/10/2014]

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PDBePISA

Protein Data Bank in Europe

Bringing Structure to Biology

PDBePISA

Protein Data Bank
in Europe