PDBe < PISA < EMBL-EBI

PISA Interface List.

Interfaces in PDB 5o83 crystal.
Space symmetry group: C 1 2 1. Resolution: 2.90 Å

DISCOVERY OF CDZ173 (LENIOLISIB), REPRESENTING A STRUCTURALLY NOVEL CLASS OF PI3K DELTA-SELECTIVE INHIBITORS

Interfaces

##		Structure 1				×	Structure 2						interface area, Å²	ΔⁱG kcal/mol	ΔⁱG P-value	N_HB	N_SB	N_DS	CSS
NN	«»	Range	ⁱN_at	ⁱN_res	Surface Å²	×	Range	Symmetry op-n	Sym.ID	ⁱN_at	ⁱN_res	Surface Å²	interface area, Å²	ΔⁱG kcal/mol	ΔⁱG P-value	N_HB	N_SB	N_DS	CSS
`1`		[9NQ]A:1101	`32`	`1`	`678`	`f`	A	x,y,z	`1_555`	`68`	`26`	`34504`	`472.8`	`1.6`	`0.364`	`1`	`0`	`0`	`0.000`
`2`		A	`30`	`13`	`34504`	`◊`	A	-x,y,-z	`2_555`	`30`	`13`	`34504`	`351.2`	`-9.7`	`0.028`	`2`	`0`	`0`	`0.000`
`3`		A	`39`	`10`	`34504`	`x`	A	x,y-1,z	`1_545`	`34`	`12`	`34504`	`300.2`	`-1.6`	`0.769`	`6`	`0`	`0`	`0.000`
`4`		A	`31`	`8`	`34504`	`◊`	A	-x,y,-z-1	`2_554`	`30`	`8`	`34504`	`246.6`	`-1.9`	`0.702`	`1`	`0`	`0`	`0.000`
`5`		A	`14`	`8`	`34504`	`x`	A	x-1/2,y-1/2,z	`3_445`	`9`	`7`	`34504`	`82.9`	`-0.4`	`0.690`	`0`	`0`	`0`	`0.000`
`6`		A	`4`	`1`	`34504`	`x`	A	x-1/2,y+1/2,z	`3_455`	`7`	`2`	`34504`	`46.3`	`-0.4`	`0.425`	`0`	`0`	`0`	`0.000`
`7`		A	`7`	`2`	`34504`	`x`	A	-x+1/2,y-1/2,-z	`4_545`	`5`	`2`	`34504`	`30.4`	`-0.4`	`0.529`	`0`	`0`	`0`	`0.000`

PDBe PISA v1.52 [20/10/2014]

Protein Data Bank
in Europe