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PISA Interface List.

Session Map (id=522-H2-O3G)

Interfaces in PDB 4v0g crystal.
Space symmetry group: P 21 21 21. Resolution: 3.00 Å

JAK3 IN COMPLEX WITH A COVALENT EGFR INHIBITOR

Interfaces

##			Structure 1				×	Structure 2						interface area, Å²	ΔⁱG kcal/mol	ΔⁱG P-value	N_HB	N_SB	N_DS	CSS
Id	NN	«»	Range	ⁱN_at	ⁱN_res	Surface Å²	×	Range	Symmetry op-n	Sym.ID	ⁱN_at	ⁱN_res	Surface Å²	interface area, Å²	ΔⁱG kcal/mol	ΔⁱG P-value	N_HB	N_SB	N_DS	CSS
1	`1`		B	`85`	`24`	`14051`	`◊`	A	-x+1/2,-y,z-1/2	`2_554`	`86`	`24`	`13518`	`858.6`	`0.7`	`0.799`	`15`	`4`	`0`	`0.000`
2	`2`		B	`74`	`23`	`14051`	`◊`	A	x,y,z	`1_555`	`74`	`19`	`13518`	`698.5`	`-9.1`	`0.183`	`3`	`3`	`0`	`0.000`
	`3`		B	`74`	`19`	`14051`	`◊`	A	x-1,y,z	`1_455`	`75`	`23`	`13518`	`675.5`	`-8.6`	`0.204`	`2`	`2`	`0`	`0.000`
	*Average:*													`687.0`	`-8.9`	`0.194`	`3`	`3`	`0`	`0.000`
3	`4`		B	`68`	`17`	`14051`	`x`	B	x-1/2,-y-1/2,-z	`4_445`	`51`	`17`	`14051`	`563.6`	`0.3`	`0.692`	`7`	`2`	`0`	`0.000`
4	`5`		[G9B]A:2099	`36`	`1`	`783`	`cf`	A	x,y,z	`1_555`	`54`	`22`	`13518`	`485.8`	`-1.8`	`0.487`	`1`	`0`	`0`	`0.100`
	`6`		[G9B]B:2099	`35`	`1`	`772`	`cf`	B	x,y,z	`1_555`	`50`	`22`	`14051`	`460.0`	`-1.6`	`0.427`	`1`	`0`	`0`	`0.100`
	*Average:*													`472.9`	`-1.7`	`0.457`	`1`	`0`	`0`	`0.100`
5	`7`		A	`18`	`7`	`13518`	`x`	A	x-1/2,-y+1/2,-z	`4_455`	`16`	`5`	`13518`	`158.3`	`-0.8`	`0.553`	`1`	`0`	`0`	`0.000`
6	`8`		B	`14`	`6`	`14051`	`◊`	A	-x,y-1/2,-z+1/2	`3_545`	`18`	`6`	`13518`	`133.1`	`-1.0`	`0.490`	`2`	`0`	`0`	`0.000`
7	`9`		B	`8`	`4`	`14051`	`x`	B	-x-1/2,-y,z-1/2	`2_454`	`6`	`3`	`14051`	`46.9`	`-0.9`	`0.188`	`1`	`0`	`0`	`0.000`
	`10`		A	`5`	`3`	`13518`	`x`	A	-x+1/2,-y,z-1/2	`2_554`	`6`	`4`	`13518`	`32.0`	`-1.1`	`0.232`	`0`	`0`	`0`	`0.000`
	*Average:*													`39.4`	`-1.0`	`0.210`	`1`	`0`	`0`	`0.000`
8	`11`		[G9B]B:2099	`2`	`1`	`772`	`◊`	[G9B]A:2099	-x+1/2,-y,z-1/2	`2_554`	`2`	`1`	`783`	`37.9`	`-1.2`	`0.236`	`0`	`0`	`0`	`0.000`
9	`12`		B	`1`	`1`	`14051`	`◊`	A	x-1/2,-y+1/2,-z	`4_455`	`1`	`1`	`13518`	`5.1`	`-0.0`	`0.513`	`0`	`0`	`0`	`0.000`

PDBe PISA v1.52 [20/10/2014]