PDBe < PISA < EMBL-EBI

PISA Interface List.

Session Map (id=374-09-22C)

Interfaces in PDB 4fa6 crystal.
Space symmetry group: C 1 2 1. Resolution: 2.70 Å

DESIGN AND SYNTHESIS OF A NOVEL PYRROLIDINYL PYRIDO PYRIMIDINONE DERIVATIVE AS A POTENT INHIBITOR OF PI3KA AND MTOR

Interfaces

##		Structure 1				×	Structure 2						interface area, Å²	ΔⁱG kcal/mol	ΔⁱG P-value	N_HB	N_SB	N_DS	CSS
NN	«»	Range	ⁱN_at	ⁱN_res	Surface Å²	×	Range	Symmetry op-n	Sym.ID	ⁱN_at	ⁱN_res	Surface Å²	interface area, Å²	ΔⁱG kcal/mol	ΔⁱG P-value	N_HB	N_SB	N_DS	CSS
`1`		A	`43`	`12`	`36597`	`◊`	A	-x,y,-z	`2_555`	`43`	`12`	`36597`	`446.7`	`-6.0`	`0.135`	`2`	`0`	`0`	`0.000`
`2`		A	`46`	`15`	`36597`	`x`	A	x,y-1,z	`1_545`	`35`	`12`	`36597`	`378.7`	`-7.0`	`0.060`	`0`	`0`	`0`	`0.000`
`3`		[0TA]A:1201	`23`	`1`	`494`	`f`	A	x,y,z	`1_555`	`49`	`21`	`36597`	`345.5`	`-0.5`	`0.182`	`1`	`0`	`0`	`0.100`
`4`		A	`41`	`15`	`36597`	`x`	A	-x+1/2,y-1/2,-z+1	`4_546`	`33`	`13`	`36597`	`297.7`	`-2.7`	`0.343`	`1`	`0`	`0`	`0.000`
`5`		A	`27`	`9`	`36597`	`◊`	A	-x,y,-z+1	`2_556`	`27`	`9`	`36597`	`282.0`	`-4.0`	`0.169`	`2`	`2`	`0`	`0.000`
`6`		A	`31`	`14`	`36597`	`x`	A	-x+1/2,y-1/2,-z	`4_545`	`33`	`11`	`36597`	`221.4`	`1.0`	`0.773`	`2`	`0`	`0`	`0.000`
`7`		A	`17`	`7`	`36597`	`x`	A	x-1/2,y-1/2,z	`3_445`	`15`	`9`	`36597`	`123.4`	`2.0`	`0.778`	`0`	`0`	`0`	`0.000`
`8`		A	`8`	`3`	`36597`	`x`	A	x-1/2,y+1/2,z	`3_455`	`3`	`1`	`36597`	`42.5`	`-0.0`	`0.625`	`0`	`0`	`0`	`0.000`
`9`		A	`1`	`1`	`36597`	`◊`	A	-x+1,y,-z	`2_655`	`1`	`1`	`36597`	`7.9`	`0.6`	`0.923`	`0`	`0`	`0`	`0.000`

PDBe PISA v1.52 [20/10/2014]

Protein Data Bank
in Europe