PDBe < PISA < EMBL-EBI

PISA Interface List.

Session Map (id=455-HI-H26)

Interfaces in PDB 4epv crystal.
Space symmetry group: P 21 21 21. Resolution: 1.35 Å

DISCOVERY OF SMALL MOLECULES THAT BIND TO K-RAS AND INHIBIT SOS- MEDIATED ACTIVATION

Interfaces

##		Structure 1				×	Structure 2						interface area, Å²	ΔⁱG kcal/mol	ΔⁱG P-value	N_HB	N_SB	N_DS	CSS
NN	«»	Range	ⁱN_at	ⁱN_res	Surface Å²	×	Range	Symmetry op-n	Sym.ID	ⁱN_at	ⁱN_res	Surface Å²	interface area, Å²	ΔⁱG kcal/mol	ΔⁱG P-value	N_HB	N_SB	N_DS	CSS
`1`		A	`52`	`13`	`8635`	`x`	A	-x+2,y-1/2,-z+1/2	`3_745`	`62`	`16`	`8635`	`561.2`	`0.7`	`0.492`	`14`	`8`	`0`	`0.000`
`2`		A	`58`	`17`	`8635`	`x`	A	x-1/2,-y+3/2,-z	`4_465`	`50`	`12`	`8635`	`442.9`	`0.6`	`0.572`	`4`	`1`	`0`	`0.000`
`3`		[GDP]A:201	`26`	`1`	`566`	`f`	A	x,y,z	`1_555`	`51`	`19`	`8635`	`364.1`	`-7.8`	`0.437`	`12`	`0`	`0`	`0.045`
`4`		A	`35`	`9`	`8635`	`x`	A	x-1,y,z	`1_455`	`34`	`9`	`8635`	`338.4`	`-1.1`	`0.374`	`5`	`1`	`0`	`0.000`
`5`		[0QX]A:203	`19`	`1`	`444`	`f`	A	x,y,z	`1_555`	`39`	`14`	`8635`	`244.4`	`-4.5`	`0.461`	`1`	`0`	`0`	`0.017`
`6`		A	`17`	`5`	`8635`	`x`	A	x-1/2,-y+1/2,-z	`4_455`	`13`	`4`	`8635`	`131.0`	`0.9`	`0.693`	`2`	`0`	`0`	`0.000`
`7`		A	`16`	`7`	`8635`	`x`	A	-x+1,y-1/2,-z+1/2	`3_645`	`16`	`5`	`8635`	`98.7`	`-0.6`	`0.418`	`0`	`0`	`0`	`0.000`
`8`		A	`8`	`3`	`8635`	`x`	A	x,y-1,z	`1_545`	`9`	`5`	`8635`	`64.4`	`0.8`	`0.707`	`0`	`0`	`0`	`0.000`
`9`		[MG]A:202	`1`	`1`	`98`	`f`	A	x,y,z	`1_555`	`17`	`9`	`8635`	`51.0`	`-6.6`	`0.000`	`0`	`0`	`0`	`0.023`
`10`		[MG]A:202	`1`	`1`	`98`	`f`	[GDP]A:201	x,y,z	`1_555`	`4`	`1`	`566`	`30.3`	`-4.6`	`0.000`	`0`	`0`	`0`	`0.016`
`11`		A	`3`	`1`	`8635`	`◊`	[0QX]A:203	x-1,y,z	`1_455`	`6`	`1`	`444`	`24.7`	`-0.7`	`0.403`	`0`	`0`	`0`	`0.000`

PDBe PISA v1.52 [20/10/2014]

Protein Data Bank
in Europe