PDBe < PISA < EMBL-EBI

PISA Interface List.

Session Map (id=225-HI-KL3)

Interfaces in PDB 4e4x crystal.
Space symmetry group: P 41 21 2. Resolution: 3.60 Å

CRYSTAL STRUCTURE OF B-RAF KINASE DOMAIN IN COMPLEX WITH A DIHYDROPYRIDO[2,3-D]PYRIMIDINONE-BASED INHIBITOR

Interfaces

##			Structure 1				×	Structure 2						interface area, Å²	ΔⁱG kcal/mol	ΔⁱG P-value	N_HB	N_SB	N_DS	CSS
Id	NN	«»	Range	ⁱN_at	ⁱN_res	Surface Å²	×	Range	Symmetry op-n	Sym.ID	ⁱN_at	ⁱN_res	Surface Å²	interface area, Å²	ΔⁱG kcal/mol	ΔⁱG P-value	N_HB	N_SB	N_DS	CSS
1	`1`		B	`113`	`32`	`13768`	`◊`	A	x,y,z	`1_555`	`116`	`33`	`13694`	`1100.9`	`-3.5`	`0.491`	`14`	`5`	`0`	`0.000`
2	`2`		B	`96`	`29`	`13768`	`◊`	B	y+1,x-1,-z	`7_645`	`95`	`29`	`13768`	`920.2`	`-7.6`	`0.221`	`2`	`0`	`0`	`0.000`
3	`3`		B	`66`	`19`	`13768`	`◊`	A	-y+1/2,x-1/2,z+1/4	`3_545`	`67`	`19`	`13694`	`666.4`	`-2.6`	`0.457`	`16`	`0`	`0`	`0.000`
4	`4`		[T1Q]B:801	`31`	`1`	`676`	`f`	B	x,y,z	`1_555`	`72`	`25`	`13768`	`464.6`	`0.2`	`0.331`	`7`	`0`	`0`	`0.100`
	`5`		[T1Q]A:801	`31`	`1`	`671`	`f`	A	x,y,z	`1_555`	`72`	`27`	`13694`	`462.7`	`-0.5`	`0.319`	`6`	`0`	`0`	`0.100`
	*Average:*													`463.6`	`-0.2`	`0.325`	`7`	`0`	`0`	`0.100`
5	`6`		A	`35`	`9`	`13694`	`◊`	B	x-1/2,-y-1/2,-z-1/4	`6_444`	`27`	`9`	`13768`	`289.7`	`-0.7`	`0.516`	`1`	`1`	`0`	`0.000`
6	`7`		A	`7`	`3`	`13694`	`◊`	B	-y-1/2,x-1/2,z+1/4	`3_445`	`8`	`3`	`13768`	`38.6`	`-0.9`	`0.348`	`0`	`0`	`0`	`0.000`
7	`8`		A	`1`	`1`	`13694`	`◊`	[T1Q]B:801	x-1/2,-y-1/2,-z-1/4	`6_444`	`1`	`1`	`676`	`10.8`	`0.3`	`0.527`	`0`	`0`	`0`	`0.000`

PDBe PISA v1.52 [20/10/2014]

Protein Data Bank
in Europe