PDBe < PISA < EMBL-EBI

PISA Interface List.

Session Map (id=517-06-DN4)

Interfaces in PDB 4dso crystal.
Space symmetry group: H 3. Resolution: 1.85 Å

SMALL-MOLECULE LIGANDS BIND TO A DISTINCT POCKET IN RAS AND INHIBIT SOS-MEDIATED NUCLEOTIDE EXCHANGE ACTIVITY

Interfaces

##		Structure 1				×	Structure 2						interface area, Å²	ΔⁱG kcal/mol	ΔⁱG P-value	N_HB	N_SB	N_DS	CSS
NN	«»	Range	ⁱN_at	ⁱN_res	Surface Å²	×	Range	Symmetry op-n	Sym.ID	ⁱN_at	ⁱN_res	Surface Å²	interface area, Å²	ΔⁱG kcal/mol	ΔⁱG P-value	N_HB	N_SB	N_DS	CSS
`1`		[GSP]A:201	`31`	`1`	`658`	`f`	A	x,y,z	`1_555`	`64`	`24`	`9048`	`438.0`	`-7.9`	`0.453`	`20`	`0`	`0`	`0.057`
`2`		A	`42`	`14`	`9048`	`x`	A	-y,x-y,z	`2_555`	`38`	`12`	`9048`	`360.0`	`-2.6`	`0.315`	`6`	`0`	`0`	`0.000`
`3`		A	`42`	`14`	`9048`	`x`	A	-x+y+2/3,-x+1/3,z+1/3	`6_555`	`43`	`12`	`9048`	`356.7`	`1.2`	`0.617`	`5`	`2`	`0`	`0.000`
`4`		A	`36`	`13`	`9048`	`x`	A	-y+1,x-y,z	`2_655`	`39`	`10`	`9048`	`327.7`	`-1.5`	`0.406`	`3`	`0`	`0`	`0.000`
`5`		A	`28`	`8`	`9048`	`x`	A	-y+2/3,x-y+1/3,z+1/3	`5_555`	`27`	`7`	`9048`	`235.8`	`2.2`	`0.794`	`2`	`1`	`0`	`0.000`
`6`		[BEN]A:203	`9`	`1`	`278`	`◊`	A	x,y,z	`1_555`	`25`	`11`	`9048`	`157.5`	`4.5`	`0.343`	`1`	`0`	`0`	`0.000`
`7`		[GOL]A:204	`6`	`1`	`216`	`f`	A	x,y,z	`1_555`	`29`	`7`	`9048`	`133.7`	`-0.0`	`0.539`	`3`	`0`	`0`	`0.005`
`8`		[BEN]A:203	`4`	`1`	`278`	`f`	A	-x+y+2/3,-x+1/3,z+1/3	`6_555`	`10`	`5`	`9048`	`50.3`	`0.5`	`0.099`	`3`	`0`	`0`	`0.003`
`9`		[MG]A:202	`1`	`1`	`98`	`f`	A	x,y,z	`1_555`	`14`	`7`	`9048`	`41.4`	`-5.7`	`0.000`	`0`	`0`	`0`	`0.020`
`10`		[MG]A:202	`1`	`1`	`98`	`f`	[GSP]A:201	x,y,z	`1_555`	`3`	`1`	`658`	`34.4`	`-4.6`	`0.000`	`0`	`0`	`0`	`0.016`
`11`		A	`5`	`4`	`9048`	`x`	A	x-1/3,y-2/3,z+1/3	`4_445`	`4`	`4`	`9048`	`22.7`	`0.1`	`0.610`	`0`	`0`	`0`	`0.000`
`12`		A	`2`	`1`	`9048`	`◊`	[GSP]A:201	-y,x-y,z	`2_555`	`2`	`1`	`658`	`15.1`	`0.3`	`0.653`	`0`	`0`	`0`	`0.000`

PDBe PISA v1.52 [20/10/2014]

Protein Data Bank
in Europe