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PISA Interface List.

Session Map (id=845-H8-534)

Interfaces in PDB 4b1c crystal.
Space symmetry group: P 21 21 21. Resolution: 1.95 Å

NEW AMINOIMIDAZOLES AS BACE-1 INHIBITORS: FROM RATIONAL DESIGN TO AB-LOWERING IN BRAIN

Interfaces

##		Structure 1				×	Structure 2						interface area, Å²	ΔⁱG kcal/mol	ΔⁱG P-value	N_HB	N_SB	N_DS	CSS
NN	«»	Range	ⁱN_at	ⁱN_res	Surface Å²	×	Range	Symmetry op-n	Sym.ID	ⁱN_at	ⁱN_res	Surface Å²	interface area, Å²	ΔⁱG kcal/mol	ΔⁱG P-value	N_HB	N_SB	N_DS	CSS
`1`		A	`46`	`15`	`16453`	`x`	A	-x,y-1/2,-z-1/2	`3_544`	`49`	`19`	`16453`	`387.6`	`0.1`	`0.662`	`7`	`5`	`0`	`0.000`
`2`		[1B1]A:1504	`24`	`1`	`576`	`f`	A	x,y,z	`1_555`	`50`	`20`	`16453`	`348.6`	`3.7`	`0.495`	`2`	`0`	`0`	`0.000`
`3`		A	`27`	`8`	`16453`	`x`	A	x-1/2,-y+1/2,-z	`4_455`	`36`	`9`	`16453`	`345.7`	`-3.5`	`0.181`	`5`	`0`	`0`	`0.000`
`4`		A	`22`	`8`	`16453`	`x`	A	-x-1/2,-y,z-1/2	`2_454`	`29`	`13`	`16453`	`251.0`	`0.4`	`0.470`	`2`	`0`	`0`	`0.000`
`5`		A	`30`	`8`	`16453`	`x`	A	x-1/2,-y-1/2,-z	`4_445`	`28`	`11`	`16453`	`246.2`	`-1.8`	`0.372`	`2`	`0`	`0`	`0.000`
`6`		A	`35`	`13`	`16453`	`x`	A	-x+1/2,-y,z-1/2	`2_554`	`29`	`8`	`16453`	`229.3`	`0.2`	`0.644`	`1`	`1`	`0`	`0.000`
`7`		[DMS]A:1503	`4`	`1`	`214`	`f`	A	x,y,z	`1_555`	`15`	`7`	`16453`	`89.5`	`1.9`	`0.427`	`1`	`0`	`0`	`0.000`
`8`		[1B1]A:1504	`15`	`1`	`576`	`f`	[DMS]A:1503	x,y,z	`1_555`	`4`	`1`	`214`	`69.5`	`1.2`	`0.198`	`0`	`0`	`0`	`0.000`
`9`		A	`2`	`2`	`16453`	`x`	A	x-1,y,z	`1_455`	`4`	`2`	`16453`	`4.9`	`-0.0`	`0.565`	`0`	`0`	`0`	`0.000`

PDBe PISA v1.52 [20/10/2014]