PDBe < PISA < EMBL-EBI

PISA Interface List.

Session Map (id=437-08-ICG)

Interfaces in PDB 4an2 crystal.
Space symmetry group: P 61. Resolution: 2.50 Å

CRYSTAL STRUCTURES OF HUMAN MEK1 WITH CARBOXAMIDE-BASED ALLOSTERIC INHIBITOR XL518 (GDC-0973), OR RELATED ANALOGS.

Interfaces

##		Structure 1				×	Structure 2						interface area, Å²	ΔⁱG kcal/mol	ΔⁱG P-value	N_HB	N_SB	N_DS	CSS
NN	«»	Range	ⁱN_at	ⁱN_res	Surface Å²	×	Range	Symmetry op-n	Sym.ID	ⁱN_at	ⁱN_res	Surface Å²	interface area, Å²	ΔⁱG kcal/mol	ΔⁱG P-value	N_HB	N_SB	N_DS	CSS
`1`		A	`52`	`19`	`13696`	`x`	A	x-y,x,z+1/6	`6_555`	`55`	`17`	`13696`	`530.9`	`-1.2`	`0.398`	`7`	`8`	`0`	`0.000`
`2`		A	`59`	`17`	`13696`	`x`	A	-y,x-y+1,z+1/3	`2_565`	`52`	`15`	`13696`	`492.1`	`-1.2`	`0.610`	`3`	`0`	`0`	`0.000`
`3`		[EUI]A:1382	`29`	`1`	`643`	`f`	A	x,y,z	`1_555`	`73`	`26`	`13696`	`439.9`	`0.6`	`0.376`	`6`	`0`	`0`	`0.012`
`4`		[ACP]A:1383	`31`	`1`	`601`	`f`	A	x,y,z	`1_555`	`63`	`24`	`13696`	`422.6`	`-2.2`	`0.562`	`5`	`0`	`0`	`0.026`
`5`		A	`23`	`6`	`13696`	`x`	A	x-y,x,z-5/6	`6_554`	`22`	`10`	`13696`	`169.4`	`2.0`	`0.842`	`2`	`3`	`0`	`0.000`
`6`		[ACP]A:1383	`6`	`1`	`601`	`f`	[EUI]A:1382	x,y,z	`1_555`	`8`	`1`	`643`	`55.9`	`0.2`	`0.375`	`1`	`0`	`0`	`0.001`
`7`		A	`6`	`2`	`13696`	`x`	A	x,y,z-1	`1_554`	`3`	`1`	`13696`	`46.4`	`0.8`	`0.743`	`1`	`0`	`0`	`0.000`
`8`		[MG]A:1384	`1`	`1`	`98`	`f`	A	x,y,z	`1_555`	`9`	`6`	`13696`	`32.6`	`-3.9`	`0.000`	`0`	`0`	`0`	`0.023`
`9`		[MG]A:1384	`1`	`1`	`98`	`f`	[ACP]A:1383	x,y,z	`1_555`	`5`	`1`	`601`	`32.4`	`-4.9`	`0.000`	`0`	`0`	`0`	`0.029`
`10`		[MG]A:1384	`1`	`1`	`98`	`f`	[EUI]A:1382	x,y,z	`1_555`	`2`	`1`	`643`	`15.3`	`-1.4`	`0.000`	`0`	`0`	`0`	`0.008`

PDBe PISA v1.52 [20/10/2014]

Protein Data Bank
in Europe