PDBe < PISA < EMBL-EBI

PISA Interface List.

Session Map (id=871-0H-3BF)

Interfaces in PDB 3tl5 crystal.
Space symmetry group: C 1 2 1. Resolution: 2.79 Å

DISCOVERY OF GDC-0980: A POTENT, SELECTIVE, AND ORALLY AVAILABLE CLASS I PHOSPHATIDYLINOSITOL 3-KINASE (PI3K)/MAMMALIAN TARGET OF RAPAMYCIN (MTOR) KINASE INHIBITOR FOR THE TREATMENT OF CANCER

Interfaces

##		Structure 1				×	Structure 2						interface area, Å²	ΔⁱG kcal/mol	ΔⁱG P-value	N_HB	N_SB	N_DS	CSS
NN	«»	Range	ⁱN_at	ⁱN_res	Surface Å²	×	Range	Symmetry op-n	Sym.ID	ⁱN_at	ⁱN_res	Surface Å²	interface area, Å²	ΔⁱG kcal/mol	ΔⁱG P-value	N_HB	N_SB	N_DS	CSS
`1`		A	`69`	`21`	`37631`	`x`	A	-x+1/2,y-1/2,-z	`4_545`	`49`	`18`	`37631`	`518.1`	`-3.5`	`0.295`	`2`	`0`	`0`	`0.000`
`2`		A	`45`	`15`	`37631`	`◊`	A	-x+1,y,-z+1	`2_656`	`45`	`15`	`37631`	`498.1`	`-4.0`	`0.288`	`8`	`0`	`0`	`0.000`
`3`		[980]A:1	`35`	`1`	`734`	`f`	A	x,y,z	`1_555`	`60`	`25`	`37631`	`476.4`	`-10.2`	`0.365`	`4`	`0`	`0`	`0.100`
`4`		A	`42`	`15`	`37631`	`x`	A	x,y-1,z	`1_545`	`37`	`11`	`37631`	`394.3`	`-6.8`	`0.047`	`2`	`0`	`0`	`0.000`
`5`		A	`45`	`17`	`37631`	`x`	A	-x+1/2,y-1/2,-z+1	`4_546`	`37`	`11`	`37631`	`340.1`	`-2.3`	`0.401`	`2`	`1`	`0`	`0.000`
`6`		A	`35`	`14`	`37631`	`x`	A	x-1/2,y+1/2,z	`3_455`	`37`	`15`	`37631`	`322.3`	`3.7`	`0.915`	`3`	`3`	`0`	`0.000`
`7`		A	`26`	`9`	`37631`	`◊`	A	-x+1,y,-z	`2_655`	`26`	`9`	`37631`	`267.3`	`-2.2`	`0.358`	`2`	`2`	`0`	`0.000`

PDBe PISA v1.52 [20/10/2014]

Protein Data Bank
in Europe

Bringing Structure to Biology

PDBePISA

Protein Data Bank in Europe

Bringing Structure to Biology

PDBePISA

Protein Data Bank
in Europe