PDBe < PISA < EMBL-EBI

PISA Interface List.

Session Map (id=396-9J-H2K)

Interfaces in PDB 2w1h crystal.
Space symmetry group: P 21 21 21. Resolution: 2.15 Å

FRAGMENT-BASED DISCOVERY OF THE PYRAZOL-4-YL UREA (AT9283), A MULTI-TARGETED KINASE INHIBITOR WITH POTENT AURORA KINASE ACTIVITY

Interfaces

##		Structure 1				×	Structure 2						interface area, Å²	ΔⁱG kcal/mol	ΔⁱG P-value	N_HB	N_SB	N_DS	CSS
NN	«»	Range	ⁱN_at	ⁱN_res	Surface Å²	×	Range	Symmetry op-n	Sym.ID	ⁱN_at	ⁱN_res	Surface Å²	interface area, Å²	ΔⁱG kcal/mol	ΔⁱG P-value	N_HB	N_SB	N_DS	CSS
`1`		A	`83`	`26`	`13848`	`x`	A	-x+3/2,-y,z-1/2	`2_654`	`72`	`20`	`13848`	`720.9`	`-0.2`	`0.695`	`11`	`8`	`0`	`0.000`
`2`		A	`60`	`18`	`13848`	`x`	A	-x+1/2,-y,z-1/2	`2_554`	`61`	`21`	`13848`	`546.9`	`-4.0`	`0.399`	`3`	`0`	`0`	`0.000`
`3`		A	`51`	`16`	`13848`	`x`	A	x-1/2,-y+1/2,-z+1	`4_456`	`52`	`14`	`13848`	`518.6`	`-1.9`	`0.488`	`9`	`2`	`0`	`0.000`
`4`		[L0F]A:1299	`23`	`1`	`496`	`f`	A	x,y,z	`1_555`	`55`	`22`	`13848`	`364.6`	`1.6`	`0.420`	`3`	`0`	`0`	`0.000`
`5`		A	`11`	`4`	`13848`	`x`	A	-x+1,y-1/2,-z+3/2	`3_646`	`11`	`6`	`13848`	`84.7`	`2.0`	`0.882`	`0`	`3`	`0`	`0.000`
`6`		A	`8`	`2`	`13848`	`x`	A	x-1,y,z	`1_455`	`5`	`2`	`13848`	`49.0`	`-0.7`	`0.343`	`0`	`0`	`0`	`0.000`

PDBe PISA v1.52 [20/10/2014]

Protein Data Bank
in Europe