PDBe < PISA < EMBL-EBI

PISA Interface List.

Session Map (id=173-03-00A)

Interfaces in PDB 1c6z crystal.
Space symmetry group: P 21 21 21. Resolution: 2.50 Å

ALTERNATE BINDING SITE FOR THE P1-P3 GROUP OF A CLASS OF POTENT HIV-1 PROTEASE INHIBITORS AS A RESULT OF CONCERTED STRUCTURAL CHANGE IN 80'S LOOP.

Interfaces

##			Structure 1				×	Structure 2						interface area, Å²	ΔⁱG kcal/mol	ΔⁱG P-value	N_HB	N_SB	N_DS	CSS
Id	NN	«»	Range	ⁱN_at	ⁱN_res	Surface Å²	×	Range	Symmetry op-n	Sym.ID	ⁱN_at	ⁱN_res	Surface Å²	interface area, Å²	ΔⁱG kcal/mol	ΔⁱG P-value	N_HB	N_SB	N_DS	CSS
1	`1`		B	`175`	`43`	`6711`	`◊`	A	x,y,z	`1_555`	`170`	`42`	`6753`	`1774.2`	`-24.0`	`0.225`	`27`	`9`	`0`	`0.791`
2	`2`		[ROC]B:505	`36`	`1`	`901`	`◊`	B	x,y,z	`1_555`	`48`	`18`	`6711`	`421.9`	`-1.7`	`0.496`	`7`	`0`	`0`	`0.102`
3	`3`		[ROC]B:505	`32`	`1`	`901`	`f`	A	x,y,z	`1_555`	`44`	`17`	`6753`	`386.3`	`-4.6`	`0.258`	`1`	`0`	`0`	`0.107`
4	`4`		B	`33`	`7`	`6711`	`◊`	A	x-1/2,-y+1/2,-z+1	`4_456`	`34`	`11`	`6753`	`316.3`	`2.5`	`0.913`	`6`	`0`	`0`	`0.000`
	`5`		B	`36`	`13`	`6711`	`◊`	A	-x+1,y-1/2,-z+3/2	`3_646`	`29`	`7`	`6753`	`308.7`	`1.7`	`0.898`	`6`	`0`	`0`	`0.000`
	*Average:*													`312.5`	`2.1`	`0.905`	`6`	`0`	`0`	`0.000`
5	`6`		B	`22`	`6`	`6711`	`◊`	A	x,y,z-1	`1_554`	`19`	`6`	`6753`	`177.4`	`-2.2`	`0.496`	`1`	`0`	`0`	`0.000`
6	`7`		A	`10`	`2`	`6753`	`x`	A	-x+1,y-1/2,-z+3/2	`3_646`	`13`	`5`	`6753`	`102.2`	`-1.4`	`0.360`	`0`	`0`	`0`	`0.000`
	`8`		B	`12`	`4`	`6711`	`x`	B	x-1/2,-y+1/2,-z+1	`4_456`	`9`	`1`	`6711`	`82.3`	`-1.8`	`0.354`	`0`	`0`	`0`	`0.000`
	*Average:*													`92.3`	`-1.6`	`0.357`	`0`	`0`	`0`	`0.000`

PDBe PISA v1.52 [20/10/2014]

Protein Data Bank
in Europe